Clinical trials: Intravascular Volume
Hemorrhage
Comparison of Compensatory Reserve Index to Intravascular Volume Change and Stroke Volume
This study is designed to validate implementation of the CRI algorithm in the CypherOx CRI system. Healthy human subjects will undergo progressive reduction in central blood volume to the point of hemodynamic instability (defined…
- Trial name
- NCT01935427
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Flashback Technologies
Hemorrhage
Comparison of Physiological Variables During Blood Donation
The investigators have developed a system based on a pulse oximeter, a tablet, and an algorithm running on the tablet that analyzes the pulse oximeter waveform.
- Trial name
- NCT02029807
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Hypoxia, Confinement
Intravascular Volumes in Hypoxia During Antarctic Confinement
This study evaluates the effect of hypoxia on blood volumes during Antarctic winter-over confinement. Half of the participants will be evaluated during sea-level winter-over confinement, while the other half will be examined…
- Trial name
- ANTARCV (NCT04106401)
- Testing
- carbon-monoxide rebreathing, venous blood sampling, physical activity monitoring
- Where
- France
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Ecole Nationale des Sports de Montagne
Sepsis
A Simple Clinical Tool to Help Assess Patient Volume (Fluid) Status
Patients may have actual or relative intravascular volume depletion in a number of different disease states, particularly with sepsis syndrome.
- Trial name
- NCT00599794
- Where
- 2 sites in United States
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Healthy Volunteers
Dynamics of Stroke Volume and Cardiac Output During Parabolic Flight, and Its Relationship to Intravascular Volume
To understand the cardiovascular reactions of the human body to changing conditions of gravity is an important aim of space science. In this context, cardiac output (CO) is a key value to estimate the human cardiovascular system.
- Trial name
- DYMCO (NCT02518880)
- Testing
- Parabolic flight, plasma volume measurements
- Where
- France
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University Hospital, Caen
Hemorrhage
Comparison of Compensatory Reserve Index to Changes in Stroke Volume and Intravascular Volume
The purpose of this study is to demonstrate the correlation of the Compensatory Reserve Index (CRI) numeric and graphical trend readings to intravascular volume changes as compared to graded blood loss (removal of 20% of…
- Trial name
- NCT02980471
- Testing
- Pulse Oximeter
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Flashback Technologies
Hypotension, Sepsis
Carotid Doppler Ultrasound for the Measurement of Intravascular Volume Status
Ultrasound represents an attractive non-invasive method to assess hemodynamic status. Understanding dynamic changes in hemodynamics in situations such as hypovolemia, sepsis, and cardiogenic shock can potentially help improve…
- Trial name
- NCT02907931
- Testing
- Point of Care Ultrasound
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Yale University