Clinical trials: Intravenous
Intravenous Access
Ultrasound-Guided Peripheral Venous Access Using AccuCath
While peripheral venous cannulation is among the most common procedures performed in clinical settings, it is estimated that PIV insertion fails for 6 million patients annually.
- Trial name
- AccuCath (NCT02469038)
- Testing
- AccuCath catheter, Control
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Anesthesia, Intravenous Anesthetic Toxicity
Comparison of the Perioperative Effects of Dexmedetomidine and Ketamine Sedation in Septorhinoplasty Operations
This randomized double-blind study aimed to compare the effects of dexmedetomidine and ketamine on hemodynamic parameters, recovery criteria, and opioid consumption and advers effects in septorhinoplasty operations.
- Trial name
- NCT04628559
- Testing
- Dexmedetomidine, Ketamine, Saline
- Where
- Turkey (Türkiye)
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Karadeniz Technical University
Dexmedetomidine, Transurethral Resection of Prostate
Intrathecal Versus Intravenous Dexmeditomedine in Transurethral Resection of the Prostate
This study is to evaluate The analgesic effect of intrathecal versus intravenous dexmeditomedine in transurethral resection of the prostate
- Conditions
- Dexmedetomidine, Transurethral Resection of Prostate, Intravenous, Intrathecal
- Trial name
- NCT04618965
- Testing
- control group, Intrathecal dexmedetomidine, Intravenous dexmedetomidine
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Tanta University
Heroin Dependence, Opioid-Related Disorders
Counseling Conditions for Buprenorphine in a Primary Care Clinic - 1
The purpose of this study is to compare the Standard Medical Management (SMM) vs. SMM enhanced with additional education about addiction and recovery (Enhanced Medical Management, EMM)
- Conditions
- Heroin Dependence, Opioid-Related Disorders, Substance Abuse, Intravenous
- Trial name
- NCT00023283
- Testing
- Buprenorphine
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Yale University
Movement After Intravenous Cannulation
Optimum Time for Intravenous Cannulation After Induction With Sevoflurane in Pediatric Patient
This study aimed to determinate effective dose 95 (ED95) intravenous cannulation in pediatric patient after induction of sevoflurane 8 vol%
- Trial name
- NCT04284579
- Testing
- IV cannula
- Where
- Indonesia
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Intravenous Cannulation
AccuVein AV400 Device Versus Ultrasound-guided Cannulation of the Great Saphenous Vein at the Ankle in Infants
Establishment of venousaccess in the age group ≤12 months can be difficult and associated with repetitive punctures . Numerous techniques to facilitate peripheral venous puncture have been described such as local warming…
- Trial name
- NCT04164862
- Testing
- AccuVein AV400 Device Versus Ultrasound-guided Cannulation
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Anxiety, Depression
The Impact of Anxiety or Depression on the Sedative Concentration of Propofol
120 consecutive female patients, 18-65 years old, American Society of Anesthesiologists (ASA) physical status I to II, scheduled for hysteroscopic surgery under propofol-based intravenous anesthesia will be recruited in this…
- Conditions
- Anxiety, Depression, Propofol, Anesthetics, Intravenous
- Trial name
- NCT03741361
- Testing
- anxiety and depression
- Where
- China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Xuyu Zhang
General Anesthesia, Intravenous Anesthesia
Combination of Magnesium and Lidocaine for the Pretreatment of Pain That is Caused by the Injection of Propofol
Since the introduction of propofol into routine anesthesia practice, the phenomena of pain on injection has plagued anesthesia providers. Propofol, an unstable phenol, triggers the release of bradykinin on injection.
- Trial name
- NCT01342510
- Testing
- Magnesium Sulfate, Lidocaine, Control
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Glaucoma and Ocular Hypertension, Diabetic Macular Edema
Effect of Dexamethasone Implant on Optic Disc
This study evaluates the effect of dexamethasone implant which is an intraocular corticosteroid on the optic nerve fibers. Retinal nerve fiber thicknesses and optic nerve head pitting rates were measured before and 6 months after…
- Conditions
- Glaucoma and Ocular Hypertension, Diabetic Macular Edema, Intravenous Drug Usage, Optic Disk Disorders
- Trial name
- NCT03927118
- Testing
- intravitreal dexamethasone implant application
- Where
- Turkey (Türkiye)
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Bulent Ecevit University
Safety and Pharmacokinetics of Intravenous Baclofen
Dose Escalation Study of Intravenous Baclofen in Healthy Adult Volunteers
The objective of this study is to determine safety and characterize pharmacokinetics of higher doses of intravenous baclofen in healthy subjects.
- Trial name
- NCT01931319
- Testing
- Intravenous baclofen
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Total Intravenous Anesthesia, Desflurane
TIVA Versus Desfluran Anaesthesia in Patients Undergoing Bariatric Surgery
Many factors during laparascopic surgery leads to PONV (postoperative nausea and vomiting), such as C02 insufflations causing peritoneal stretch and irritation and type of anaesthesia given during surgery.
- Conditions
- Total Intravenous Anesthesia, Desflurane, Obesity, Pain, Postoperative
- Trial name
- NCT03727607
- Testing
- Desflurane
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Ostfold Hospital Trust
Elective Surgery, Intravenous Anesthesia
Preoperative Anxiety's Incidence and Related Factors in Surgical Patients
Preoperative anxiety is often described as an uncomfortable, tense unpleasant mood before surgery, an emotional response to a potential challenge or threat to reality.
- Conditions
- Elective Surgery, Intravenous Anesthesia, Preoperative Anxiety
- Trial name
- NCT03162692
- Where
- China
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Xuzhou Medical University
Intravenous Baclofen
Repeated Dose IV Baclofen Safety/Bioequivalence Study
The purpose of this study is to identify a suitable dosing regimen of IV baclofen to serve as a temporary substitute for an oral regimen.
- Trial name
- NCT02760992
- Testing
- IV Baclofen, Oral Baclofen
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Allaysis, LLC
Substance-Related Disorders, Alcohol-Related Disorders
Conflict Between Maternal Autonomy and Child Health in Substance-use
Qualitative project, comprising open-ended semi-structured interviews with healthcare workers, who provide antenatal care to substance-using women.
- Conditions
- Substance-Related Disorders, Alcohol-Related Disorders, Amphetamine-Related Disorders, Inhalant Abuse
- Trial name
- NCT02797990
- Where
- United Kingdom
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- London School of Hygiene and Tropical Medicine
Anesthesia, General, Anesthesia, Intravenous
Evaluation of a Novel Closed-loop Propofol and Remifentanil System Guided by Bispectral Index Compared to a TCI Open-loop System
Closed loop system in intravenous anesthesia is more effective to maintain depth of anesthesia compared with manual system open, it is unclear what driver and variables to achieve this goal be more physiological; in the…
- Trial name
- NCT02492282
- Testing
- Closed-Loop propofol and remifentanil system by Bispectral Index, Open-Loop propofol and remifentanil by Target Controlled Infusion, propofol
- Where
- Colombia
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Universidad de Antioquia
Peripheral Intravenous Catheters
RIGHT IV Pilot Study
The purpose of this pilot study is to collect the necessary information for determining the appropriate sample size of a statistically powered trial comparing the performance of two different blood control peripheral intravenous…
- Trial name
- RIGHT IV (NCT01792778)
- Testing
- ViaValve Safety IV Catheter, Insyte Autoguard BC [Blood Control] Shielded IV Catheter
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Smiths Medical, ASD, Inc.
Safety and Pharmacokinetics of Intravenous Ascorbate
Evaluation of Intravenous Ascorbic Acid
This Phase I study will be conducted in 2 parts to examine safety and pharmacokinetics of escalating doses of intravenous ascorbic acid (AA) first in healthy volunteers followed by evaluation in oncology subjects.
- Trial name
- NCT01833351
- Testing
- IV Vitamin C
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University of Kansas Medical Center
Length of Labor, Second Stage of Labor
Effects of Rate and/or Presence of Dextrose on the Labor Course of Nulliparas
This randomized controlled trial aims to compare three groups of intravenous fluids and their impact on labor: 1) 125 mL/hr of 5% dextrose in normal saline 2) 250 mL/hr of normal saline 3) 250 mL/hr of 5% dextrose in normal saline
- Conditions
- Length of Labor, Second Stage of Labor, Intravenous Hydration of Labor
- Trial name
- NCT01904617
- Testing
- Dextrose, Normal Saline
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- MemorialCare Health System
Intravenous Drug Usage
Correlates and Consequences of Increased Immune Activation in Injection Drug Users
The goal of this study is to learn how injection drug use may affect the immune system.
- Trial name
- NCT01831284
- Testing
- Sigmoidoscopy with biopsy
- Where
- United States
- Volunteers
- 201 people, healthy volunteers welcome
- Sponsor
- Rockefeller University
Abdominal Aortic Aneurysm > 5.5 cm Effect of a Restricted Intravenous Fluid Regime on Complications and Hospital Stay After the Minilaparotomy AAA Repair.
Restrictive Versus Standard Fluid Regime in Elective Minilaparotomy Abdominal Aortic Aneurysm Repair
Elective minilaparatomy abdominal aortic aneurysm (AAA) repair is associated with a significant number of complications involving respiratory, cardiovascular, gastrointestinal and central nervous system, and mortality ranging up…
- Trial name
- NCT01939652
- Testing
- Restrictive VS Standard Fluid Regime, Drag: Crystalloids and Colloids
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University Clinical Center Tuzla