Clinical trials: Intravenous Therapy
Prostate Cancer
Estramustine, Etoposide and Paclitaxel Treatment for Hormonally Responsive Adenocarcinoma of the Prostate
Hormonal therapy is the standard treatment for prostate cancer which has spread to other areas of the body. Despite the high initial response rates to hormonal therapy, the vast majority of men will develop cancer which is no…
- Trial name
- NCT00151060
- Testing
- Estramustine, Etoposide, Paclitaxel
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- University of Michigan Rogel Cancer Center
Lung Transplantation, Donor-specific Anti-human Leukocyte Antigen(HLA) Antibodies
Monitoring of Donor-specific Antibodies After Treatment With Immunoglobulins, Plasmapheresis and Rituximab in Lung Transplantation
Single-arm, prospective observational study
- Trial name
- NCT03798860
- Testing
- blood samples
- Where
- Germany
- Volunteers
- 340 people
- Sponsor
- Hannover Medical School
Heart Failure
IVIg Therapy for Patients With Idiopathic Cardiomyopathy and Endomyocardial Biopsy Proven High PVB19 Viral Load
Rationale: Parvovirus B19 (PVB19) persistence in the heart has been associated with progressive cardiac dysfunction and evolution to dilated cardiomyopathy.
- Trial name
- NCT00659386
- Testing
- Intravenous immunoglobulin therapy
- Where
- Netherlands
- Volunteers
- 40 people
- Sponsor
- Maastricht University Medical Center
Solid Tumors
GLPG0187: Safety, Tolerability and Pharmacokinetics in Patients With Solid Tumors
The purpose of the study is to determine the safety and tolerability of GLPG0187 administered through continuous intravenous infusion and to explore its preliminary clinical efficacy in patients with solid tumors.
- Trial name
- NCT01313598
- Testing
- GLPG0187
- Where
- 2 sites in Netherlands
- Volunteers
- 20 people
- Sponsor
- Lakefront Biotherapeutics NV
Influenza
Peramivir Treatment Response in Adults Hospitalized for Influenza-associated Lower Respiratory Tract Infections
Peramivir is the first intravenous neuraminidase inhibitor (NAI) available for treatment of uncomplicated influenza in adults. Data from placebo-controlled trials in outpatients have shown antiviral efficacy, safety, and…
- Trial name
- NCT02665351
- Testing
- Peramivir
- Where
- China
- Volunteers
- 16 people
- Sponsor
- Chinese University of Hong Kong
Iron Deficiency Anemia in Pregnancy
Comparing Two Intravenous Iron Treatments for Anemia in Kurdish Pregnant Women
The goal of this clinical trial is to compare two types of intravenous (IV) iron-Ferric Carboxymaltose (FCM) and Iron Sucrose (IS)-to learn which one works better to treat iron deficiency anemia in pregnant women who have a clear…
- Trial name
- NCT07721519
- Testing
- Intravenous Ferric Carboxymaltose (FCM), Iron Sucrose (IS) Infusion
- Volunteers
- 400 people
- Sponsor
- Hawler Medical University
Covid19
Study of Allogeneic Adipose-Derived Mesenchymal Stem Cells for Treatment of COVID-19 Acute Respiratory Distress
This is a Phase 2 study to assess COVI-MSC in the setting of current standard of care in hospitalized subjects with RT-PCR confirmed SARS-CoV-2 (COVID-19) infection and acute respiratory distress / acute respiratory distress…
- Trial name
- NCT04905836
- Testing
- COVI-MSC
- Where
- 6 sites in United States
- Volunteers
- 60 people
- Sponsor
- Sorrento Therapeutics, Inc.
Covid19, Pneumonia
Intravenous Immunoglobulin (IVIG, Bioven) Efficacy Assess for COVID-19 / SARS-CoV-2 Severe Pneumonia Complex Treatment
Pneumonia caused by coronavirus infection COVID-19 is characterized by a combination of several dangerous factors that consistently worsen the patient's condition: viral lung damage early in the disease; a sharp increase in…
- Trial name
- NCT04500067
- Testing
- IVIG
- Where
- 9 sites in Ukraine
- Volunteers
- 76 people
- Sponsor
- Biopharma Plasma LLC
Candidiasis, Chronic Mucocutaneous
CAMB/MAT2203 in Patients With Mucocutaneous Candidiasis
This is an open-label, dose-titration trial to study the efficacy, safety, and pharmacokinetics of oral cochleate amphotericin B (CAMB) in the treatment of mucocutaneous candidiasis infections in patients who are refractory or…
- Trial name
- CAMB (NCT02629419)
- Testing
- Amphotericin B
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Matinas BioPharma Nanotechnologies, Inc.
Cerebral Palsy
Safety of Cultured Allogeneic Adult Umbilical Cord or Placental Derived Mesenchymal Stem Cell Intravenous Infusion for CP
This trial will study the safety and efficacy of intravenous infusion of cultured allogeneic adult umbilical cord or placental derived mesenchymal stem cells for the treatment of Cerebral Palsy
- Trial name
- NCT05018819
- Testing
- cultured allogeneic adult umbilical cord or placental derived mesenchymal stem cells
- Where
- 2 sites in United States, Greece
- Volunteers
- 15 people
- Sponsor
- The Foundation for Orthopaedics and Regenerative Medicine
Analgesia, Post Operative Pain
Morphine vs Sufentanil PCA: Same Same or Different?
Patient-controlled intravenous analgesia (PCA) has already proven its quality. However, with new strategies starting to emerge and the current concept of opioid sparing, it is a goal to find the optimal PCA strategy capable of…
- Conditions
- Analgesia, Post Operative Pain, Patient Satisfaction, Chronic Pain
- Trial name
- NCT05259098
- Testing
- Sufentanil Sublingual Tablet System, Intravenous Patient-Controlled Analgesia with morfine
- Where
- Portugal
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Hospital Central do Funchal
Endometrium, Laser
Intravenous Laser Irradiation Effect on Treatment Resistant Thin Endometrium
We will recruit 30 poor ovarian responders and thin endometrium patients, aged 35-45 year old, and treat with intravascular laser irradiation of blood (ILIB) via an intravenous catheter for irradiation of the blood under a period…
- Trial name
- NCT03081130
- Testing
- Intravenous laser irradiation treatment
- Where
- Taiwan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Kaohsiung Veterans General Hospital.
Multiple Sclerosis
Mesenchymal Stem Cells for the Treatment of MS
Although, effective immunotherapies for MS exist which downregulate the anti-myelin reactivity and reduce the rate of relapses of the disease, there is no effective means today to stop the progression of disability and induce…
- Trial name
- NCT00781872
- Testing
- Injection of autologous bone marrow derived mesenchymal stem cells
- Volunteers
- 24 people
- Sponsor
- Hadassah Medical Organization
HIV, Hepatitis C
THISTLE - The HIV-HCV Silibinin Trial
Chronic hepatitis C virus (HCV) is a major cause of morbidity and mortality worldwide with an estimated number of 180 million infected patients.
- Trial name
- THISTLE (NCT01816490)
- Testing
- Intravenous Silibinin (iSIL)
- Where
- Switzerland
- Volunteers
- 20 people
- Sponsor
- University of Zurich
Cytomegalovirus Retinitis, HIV Infections
A Study of Ganciclovir in the Treatment of Cytomegalovirus of the Eyes
To determine whether alternating oral ganciclovir with intravenous ( IV ) ganciclovir can prevent relapse of Cytomegalovirus ( CMV ) retinitis and improve quality of life in AIDS patients.
- Trial name
- NCT00001062
- Testing
- Ganciclovir
- Where
- 6 sites in United States
- Volunteers
- 25 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Acute Stroke
Intravenous Autologous Bone Marrow-derived Stem Cells Therapy for Patients With Acute Ischemic Stroke
A multi-centric initiative to study safety,feasibility and efficacy of using intravenous autologous bone marrow mononuclear cells(BMMC) in patients with acute ischemic stroke.This phase of study is visualised as phase 2 study and…
- Trial name
- NCT01501773
- Testing
- Autologous bone marrow stem cell
- Where
- 5 sites in India
- Volunteers
- 120 people
- Sponsor
- Manipal Acunova Ltd.
Intravenous Immunoglobulin (IVIg) Therapy in a Home Infusion Setting
Gamma Globulin Observations and Outcomes Database for Specific Home Infusion Evidence, Patient Care And Research Data (GOOD-SHEPARD)
Primary: Demonstrate the utility of a new electronic data capture (EDC) system (CareExchange™) using infusion nurse measured physical, quality of life (QOL), respiratory, and disability assessments.
- Trial name
- GOOD-SHEPARD (NCT01774331)
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- BriovaRx Infusion Services
Multiple Sclerosis, Relapsing-Remitting
A Study to Evaluate Efficacy, Safety, and Tolerability of EID of Natalizumab (BG00002) in Participants With RRMS Switching From Treatment With Natalizumab SID in Relation to Continued SID Treatment- Followed by Extension Study Comprising SC and IV Natalizumab Administration
Part 1: The primary objective is to evaluate the efficacy of natalizumab extended interval dosing (EID) (every 6 weeks [Q6W]) in participants who have previously been treated with natalizumab standard interval dosing (SID) (every…
- Trial name
- NCT03689972
- Testing
- Natalizumab
- Where
- 107 sites in United States, Australia and 9 more
- Volunteers
- 585 people
- Sponsor
- Biogen
Migraine Disorders
Efficacy, Safety, Tolerability and Pharmacokinetics of BIBN 4096 BS Versus Placebo in the Treatment of a Single Attack of Acute Migraine Headache
Efficacy, Safety, Tolerability and Pharmacokinetics of BIBN 4096 BS in patients with a single acute migraine attack with or without aura
- Trial name
- NCT02198339
- Testing
- BIBN 4096 BS
- Volunteers
- 126 people
- Sponsor
- Boehringer Ingelheim
Renal Colic
Analgesic Effect of Erector Spinae Plane Block for Renal Colic Pain
Plane blocks have become very popular in recent years with the introduction of ultrasonography into the regional anesthesia and algology practice.
- Trial name
- NCT04209439
- Testing
- 30 ml %0.25 bupivacaine, Dexketoprofen-trometamol
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Ataturk University