Clinical trials: Inulin
Healthy, Constipation
Effect of Consumption of Orafti® Inulin on Bowel Motor Function in Subjects With Constipation
Investigation of the effects of a four week daily consumption of Orafti® Inulin on bowel motor function in subjects with constipation.
- Trial name
- NCT02548247
- Testing
- Orafti® Inulin
- Where
- Germany
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Beneo GmbH
Iron Absorption, Gut Bacteria
Effect of Inulin on Iron Absorption in Humans
Prebiotics are non-digestible food ingredients that beneficially affect the host by selectively stimulating the growth or activity of species in the colon that can improve host health.
- Trial name
- NCT01483092
- Testing
- inulin, maltodextrin
- Where
- Switzerland
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
Irritable Bowel Syndrome
Effect of Pre-dosing With Methylcellulose or Psyllium on Colonic Fermentation of Inulin
The aim for this pilot study is to test the hypothesis that pre-dosing with gel-forming dietary fibres (methylcellulose or psyllium) will alter the colonic fermentation of a model fermentable dietary fibre (Inulin) when delivered…
- Trial name
- COCOA3 (NCT06494137)
- Testing
- inulin
- Where
- United Kingdom
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Infant Development, Healthy
Prebiotic EffecT InfanTs
The study aims to confirm the effectiveness of chicory-derived prebiotic inulin-type fructans on stool consistency in infants.
- Conditions
- Infant Development, Healthy, Diet, Healthy
- Trial name
- PETIT (NCT04791956)
- Testing
- Prebiotic
- Where
- 2 sites in Spain
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Beneo-Institute
Colon, Irritable
Effect of Methylcellulose or Psyllium on Fermentation of inUlin Assessed USing MRI
The challenge is to understand how fibre interacts with whole-gut function to alter colonic fermentation of fermentable oligo-di- and mono-saccharides and polyhydric alcohols (FODMAPs).
- Trial name
- RUFUS (NCT06291272)
- Testing
- Psyllium, Methylcellulose, Inulin
- Where
- United Kingdom
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Diet, Healthy
Chicory Fiber Effect on Satiety and GI Tolerance
The investigators are comparing 2 fiber treatments to a fiber free treatment for acute satiety and GI response.
- Trial name
- NCT04067362
- Testing
- food containing dietary fiber
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Healthy
Effects of a Diet Based on Inulin-rich Vegetables on Gut Health and Nutritional Behaviour in Healthy Humans
Inulin-type fructans (ITF) are fermentable dietary fibres that can confer beneficial health effects through changes in the gut microbiota. However, their effect on gut sensitivity and nutritional behaviour is a matter of debate.
- Trial name
- NCT03540550
- Testing
- Diet based on inulin-rich vegetables
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Pre-Eclampsia
Glomerular Injury of Preeclampsia
Pre-eclampsia complicates 7 - 10% of pregnancies and constitutes a leading cause of fetal growth retardation and premature birth, as well as infant and maternal morbidity and mortality.
- Trial name
- NCT00275158
- Testing
- L-Arginine Supplementation
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Insulin Sensitivity
Insulin Sensitivity and Testosterone Response to Aerobic Exercise Versus Added Sugar Elimination in Polycystic Ovary Syndrome Women
the aim of this study is to investigate the effect of aerobic exercise versus the effect of added sugar elimination on the insulin sensitivity and testosterone levels in females with polycystic ovarian syndrome via measuring the…
- Trial name
- NCT07139275
- Testing
- aerobic exercise, added sugar elimination, aerobic exercise and added sugar elimination
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cairo University
Healthy
Influence of Food Matrix on Prebiotic Efficacy in Inulin Type Fructans
The aim of the study is to investigate whether the food matrix has an influence on the prebiotic efficacy (bifidobacteria growth) of chicory-derived Orafti® inulin in healthy adult volunteers.
- Trial name
- NCT05581615
- Testing
- Inulin
- Where
- United Kingdom
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Beneo-Institute
NAFLD
The Role of Microbiome Reprogramming on Liver Fat Accumulation
The purpose of this study is to investigate whether reprogramming the microbiome via soluble fiber supplementation will decrease liver fat in obese individuals.
- Trial name
- MILE (NCT03914495)
- Testing
- Inulin
- Where
- United States
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- AdventHealth Translational Research Institute
Infectious Disease, Children, Only
Effect of Prebiotic Fructans to Reduce Number of Febrile Infections in Children
The study aims to confirm the effectiveness of chicory-derived prebiotic inulin-type fructans on the reduction of the number of febrile infections diagnosed by the paediatrician in children.
- Conditions
- Infectious Disease, Children, Only, Diet Modification
- Trial name
- NCT03457688
- Testing
- prebiotic inulin-type fructans
- Volunteers
- 850 people, healthy volunteers welcome
- Sponsor
- Beneo-Institute
Metabolic Syndrome
Effect of Functional Foods on Gut Microbiota in Metabolic Syndrome
Aim: To study the effect of a combination of functional foods on gut microbiota in subjects with metabolic syndrome. Subjects that met the metabolic syndrome criteria were enrolled in a double-blind, parallel-arm, placebo-control…
- Trial name
- MetS (NCT03611140)
- Testing
- DP
- Where
- Mexico
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran
Inulin, IBS (Irritable Bowel Syndrome)
The Effect of Inulin Supplementation in Individuals With IBS-C
Background: This study aimed to evaluate the effects of inulin supplementation on nutritional intake, anthropometric parameters, and bowel symptoms in individuals diagnosed with IBS-C.
- Conditions
- Inulin, IBS (Irritable Bowel Syndrome), Nutritional Status, Anthropometric Measurement
- Trial name
- NCT06945302
- Testing
- Intervention Group
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Mardin Artuklu University
Obesity, Pre Diabetes
Inulin and Acetate Production and Human Substrate Metabolism
Based on our hypothesis that orally administered resistant starch and inulin/beta glucan will be fermented into a SCFA pattern high in acetate and that this will lead to beneficial effects on human substrate and energy…
- Trial name
- NCT03711383
- Testing
- Inulin and Resistant Starch, Inulin
- Where
- Netherlands
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Healthy
Satiety Response of Four Dietary Fibers
Studies have found a relationship between dietary fiber consumption and body weight regulation. This relationship may stem from enhanced satiety through fermentation of certain fibers in the large intestine.
- Trial name
- NCT01233024
- Testing
- Control, Soluble corn fiber, Resistant starch
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Irritable Bowel Syndrome
Effect of Chronic Feeding of Inulin And Methylcellulose on Colonic Fermentation
To determine the effect on tolerance and gas production from chronic feeding of fermentable fibre (inulin) incorporated into a gel forming fibre (methylcellulose) compared with placebo (maltodextrin)
- Trial name
- CINNAMON (NCT06551961)
- Testing
- methylcellulose, inulin, maltodextrin
- Where
- 2 sites in United Kingdom
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Gut Microbiota, Adiposity
Effect of a Synbiotic on the Gut Microbiota and Adiposity-related Markers in Healthy Overweight Subjects
The purpose of this study is to investigate the effects of a synbiotic (ProSynbiotic) on the gut microbiota composition, body composition and adiposity-related genes and metabolic markers in healthy overweight adult subjects.
- Trial name
- NCT02151825
- Testing
- Synbiotic
- Where
- United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Texas State University, San Marcos
Exercise, Inulin Propionate Ester
Impact of Exercise Combined With Inulin Propionate Ester on Fat Oxidation
There is evidence to suggest that responsiveness to exercise training programmes can be expected to be influenced by changes in resting fat oxidation, an important factor in the aetiology of obesity.
- Trial name
- IPE (NCT04016350)
- Testing
- Exercise training with Inulin Propionate Ester
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Glasgow
Acne Vulgaris
"A Comparative Clinical Evaluation of the Efficacy of Topical Adapalene, Benzoyl Peroxide Gel, Oral Lactobacillus Rhamnosus, D-chiro-inositol, Inulin Capsule, and Their Fixed Combination in Mild to Moderate Acne Vulgaris Patients."
The study aims to conduct a comparative clinical evaluation of the effectiveness of a fixed topical combination of adapalene with benzoyl peroxide in the form of a gel, a fixed combination of Lactobacillus rhamnosus…
- Trial name
- NCT05855629
- Testing
- Oral Lactobacillus Rhamnosus, D-chiro-inositol, Inulin Capsule, Topical Adapalene, Benzoyl Peroxide Gel
- Where
- Ukraine
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Treatment and Diagnostic Center of Private Enterprise "Asklepiy"