Clinical trials: Investigation Time
Small Bowel Bacterial Overgrowth, Gastrointestinal Diseases
Transit Time and Bacterial Overgrowth Using SmartPill Capsule
The primary purpose of this exploratory study is to measure orocecal transit time using the SmartPill ambulant capsule technology and to compare this with the lactulose hydrogen breath test.
- Conditions
- Small Bowel Bacterial Overgrowth, Gastrointestinal Diseases, Stomach Diseases, Digestive System Diseases
- Trial name
- NCT00577772
- Testing
- Xifaxan, SmartPill, Lactulose hydrogen breath test (H_2BT)
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Congenital Heart Disease
Real-time 3-Dimensional Echocardiography for Assessment of Cardiac Function and Congenital Heart Disease
The propose of this study is to generate normative data of the tree-dimensional echocardiographic(3-DE) measurements for cardiac structure and function in a large cohort of normal infants, children,and adolescents.
- Trial name
- 3DE-CHD (NCT01300221)
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Drexel University
Postural Disorders, Balance Problems
Investigation of the Effect of Screen Time Before Sleep on Posture Disorders and Dynamic Balance
The widespread use of electronic devices such as smartphones, tablets, and laptops has significantly increased screen exposure, especially before sleep.
- Trial name
- NCT07541963
- Testing
- Pre-sleep screen exposure assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Periodontitis
The Effect of Time on the Outcome of Periodontal Treatment.
Re-evaluation after non-surgical periodontal treatment remains an integral part of comprehensive periodontal therapy. This re-evaluation determines if a patient is in need either of surgical periodontal therapy or a personalized…
- Trial name
- NCT05643287
- Testing
- Periodontal treatment
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- 251 Hellenic Air Force & VA General Hospital
Chronic Periodontitis
Methodological Evaluation of Gingival Crevicular Fluid Volume and Elastase Level
The mechanisms underlying the formation and composition of gingival crevicular fluid (GCF) and its flow into and from periodontal pockets are not understood very well.
- Trial name
- NCT02676362
- Testing
- Gingival crevicular fluid collection with filter paper
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Baskent University
Infantile Colic
Evaluation of Safety and Efficacy of New Infant Formula in Infantile Colic
The study is conducted to examine the safety and efficacy of a new infant formula and its effects on the gastrointestinal tolerance in infants suffering from colic.
- Trial name
- Coco (NCT01721850)
- Testing
- control formula, intervention formula 1, intervention formula 2
- Where
- 18 sites in Germany, Italy
- Volunteers
- 169 people, healthy volunteers welcome
- Sponsor
- HiPP GmbH & Co. Vertrieb KG
Semen Exposure
Residence Time of Biomarkers of Semen Exposure
The purpose of this study is to examine the vaginal residence time of certain semen biomarkers.
- Trial name
- NCT00984555
- Where
- 2 sites in United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- CONRAD
Patellofemoral Pain Syndrome, ACL Tear
Kinematic Assessment of Human Peripheral Joints by Dynamic CT
Aim of the research project: The entire research project aims to investigate human peripheral joints (knee, foot \& ankle, elbow, wrist \& hand) by dynamic 4D radiographic imaging acquisition during real-time motion.
- Trial name
- Karma-4D (NCT04732585)
- Testing
- Physiotherapy or Surgery
- Where
- Belgium
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universitair Ziekenhuis Brussel
Antiplatelet Effect
Bleeding Time Study With AZD6482, Clopidogrel and ASA
The primary purpose of this study is to evaluate the effect of AZD6482 and clopidogrel on bleeding time when taken together with low-dose ASA.
- Trial name
- NCT00853450
- Testing
- AZD6482, Clopidogrel, ASA
- Where
- Sweden
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Urge Incontinence, Urgency-frequency Syndrome
Percutaneous Nerve Evaluation Trial Time
Sacral neuromodulation (SNM) was approved by the Food and Drug Administration (FDA) for the treatment of urgency incontinence (UUI) in 1998.
- Conditions
- Urge Incontinence, Urgency-frequency Syndrome, Overactive Bladder
- Trial name
- NCT06226220
- Testing
- Sacral neuromodulation
- Where
- United States
- Volunteers
- 193 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Aerosol Therapy, Asthma
Evaluation of Time-Sensitive Nebulization Mode Converter
This study utilizes a randomized crossover design to evaluate and compare the clinical and technical efficacy of different nebulization modes for aerosol drug delivery.
- Trial name
- NCT07633223
- Testing
- Cross-over Nebulization Modes Comparison System
- Where
- Egypt
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Beni-Suef University
Neoadjuvant Chemoradiotherapy, Rectal Tumor
Outcomes of Resection at Different Times Between the End of Neoadjuvant Treatment and Surgery
Neoadjuvant radio-chemotherapy (NRCT) represents a milestone in the treatment of selected rectal tumours. Ideal time interval between the end of NRCT and surgery is still debated; a 6-8 weeks time interval is considered optimal…
- Conditions
- Neoadjuvant Chemoradiotherapy, Rectal Tumor, Surgery, Surgery--Complications
- Trial name
- NCT04013347
- Testing
- Rectal Resection
- Volunteers
- 167 people, healthy volunteers welcome
- Sponsor
- Campus Bio-Medico University
Instrumentation Time
Comparative Evaluation of Instrumentation Time Using Pediatric Rotary Versus Hand (Flare) File Systems
The study will be conducted to evaluate instrumentation time, obturation quality, and child's behavior using pediatric rotary versus hand flare file systems in treatment of primary molars.
- Trial name
- NCT05665803
- Testing
- Pediatric rotary files, Manual flare files
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Cairo University
Pediatric Obesity
Monitoring Eating Across Locations (MEAL) - Timing, Intake, and Mealtime Evaluation (TIME)
Increased availability of high-energy dense foods has contributed to a pediatric obesity epidemic, with 23% of United States children currently presenting with the disease.
- Trial name
- MEAL-TIME (NCT07095166)
- Testing
- Meal Location
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Penn State University
Healthy
Evaluation of Bacillus Subtilis R0179 in Healthy Young Adults
The purpose of this study is to evaluate the effect of three doses of the probiotic B. subtilis (Bacillus subtilis R0179) delivered in capsules on gastrointestinal and general wellness in healthy young adults, survival through…
- Trial name
- NCT01802151
- Testing
- B. subtilis R0179
- Where
- United States
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- University of Florida
Anticoagulation Reversal
Study of PER977 Administered to Subjects With Steady State Edoxaban Dosing and Re-anticoagulation With Edoxaban
This study will evaluate the establishment of anticoagulation ("re-anticoagulation") of subjects with edoxaban following reversal by PER977 and will identify a dose regimen of PER977 that reverses the effects of edoxaban for up…
- Trial name
- NCT02207257
- Testing
- PER977, Edoxaban
- Where
- United States
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Perosphere Pharmaceuticals Inc, a wholly owned subsidiary of AMAG Pharmaceuticals, Inc.
Ebola Virus Disease, Marburg Virus Disease
Evaluation of Safety, Tolerability and Immune Responses of Ebola-S and Marburg Vaccines in Healthy Adults
Primary Objective: To evaluate the safety and tolerability of cAd3-EBO-S and cAd3 Marburg vaccines when administered Intramuscular (IM) at a dose of 1 x 10^11 particle units (PU) to healthy adults.
- Trial name
- NCT04723602
- Testing
- cAd3-Marburg, cAd3-EBO-S
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Albert B. Sabin Vaccine Institute
Breast Carcinoma, Kidney Carcinoma
Functional Near-Infrared Spectroscopy and Virtual Reality Relaxation Programs for Pain Management in Patients With Cancer
This study aims to develop objective tools for assessing perceived pain severity in cancer patients and survivors, evaluate the sustained effectiveness of non-pharmacological interventions such as virtual reality in reducing pain…
- Conditions
- Breast Carcinoma, Kidney Carcinoma, Carcinoma
- Trial name
- NCT06456411
- Testing
- Functional Near-Infrared Spectroscopy, Questionnaire Administration, Virtual Technology Intervention
- Where
- United States
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- Roswell Park Cancer Institute
Cancer, Aging
Real-time Behavioral Interventions
The goal of this study is to adapt an evidence-based sedentary behavior reduction intervention for men and women living in Alabama and determine its feasibility, acceptance, and limited efficacy.
- Conditions
- Cancer, Aging, Comorbidities and Coexisting Conditions
- Trial name
- NCT04457128
- Testing
- Just-in-Time Adaptive Intervention
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Alabama, Tuscaloosa
Smoking, Low Physical Activity Level
Perfect Fit: Evaluation of a Virtual Coach for Smoking Cessation and Physical Activity
The leading cause of disease burden across the globe is cardiovascular disease (CVD). Important modifiable behavioral CVD risk factors include, amongst others, smoking and low physical activity (PA).
- Trial name
- NCT06095999
- Testing
- Perfect Fit intervention: virtual coaching intervention to quit smoking and increase physical activity
- Where
- Netherlands
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Leiden University Medical Center