Clinical trials: Investigation Time
Inflammatory Bowel Diseases
GSK2983559 First Time in Human Study
This study is the first administration of GSK2983559, a selective receptor interacting protein 2 (RIP2) kinase inhibitor, to humans. This will be randomized, double-blinded (sponsor open) and two part study (A and B).
- Trial name
- NCT03358407
- Testing
- GSK2983559
- Where
- United Kingdom
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Cicatrix, Wound-healing
Investigation Into the Safety and Scar-improvement Efficacy of Intradermal Juvidex Dosed Once or Three Times
The purpose of this study was to investigate the scar-improvement efficacy of three doses of intradermal Juvidex given once only or three times in male and female subjects and to collect further safety and tolerability data for…
- Trial name
- NCT00984516
- Testing
- Juvidex
- Where
- United Kingdom
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Renovo
Cirrhosis, Chronic Liver Disease
Real Time Elastography in Liver Fibrosis
AIM To evaluate the role of real time elastography (ARFI and Hitachi elastography) in noninvasive diagnosis of liver fibrosis in patients with chronic hepatitis
- Trial name
- RT-ELASTO (NCT01948687)
- Where
- 2 sites in Romania
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- University of Medicine and Pharmacy Craiova
Emergencies, Cardiovascular Diseases
Ultrasound Evaluation of the Jugular Venous Pulse (US-JVP)
The jugular venous pulse (JVP) reflects changes in the right atrial pressure and its evaluation can be useful in managing many emergency conditions for guiding the fluid administration as well as in the diagnosis and/or prognosis…
- Conditions
- Emergencies, Cardiovascular Diseases, Neurovascular Disorders
- Trial name
- US-JVP (NCT03917368)
- Testing
- Ultrasound scan of the internal jugular veins
- Where
- Italy
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- S. Anna Hospital
Movement Disorder, Tourette Syndrome
Investigation of Neurofeedback With Real-Time fMRI in Healthy Volunteers and Patients With Hyperkinetic Movement Disorders
Background: Many people can learn to use feedback about brain activity to modify that activity, but is it not known if people with Tourette syndrome can modify their brain activity.
- Conditions
- Movement Disorder, Tourette Syndrome, Healthy Volunteer
- Trial name
- NCT00885040
- Where
- United States
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Screen Time Exposure
Reactions to Social Media Warning Labels Among Teens and Young Adults
The primary objective of this study is to evaluate whether social media warnings are perceived as more effective than control labels among teens and young adults, and to identify the most promising topics for social media…
- Trial name
- NCT07199660
- Testing
- Human-developed negative body image warning, Voluntary warning, Human-developed depression and anxiety warning
- Where
- United States
- Volunteers
- 1,012 people, healthy volunteers welcome
- Sponsor
- Stanford University
Arrhythmogenic Cardiomyopathy
Subcutaneous Implantable Cardioverter-defibrillator (S-ICD) Eligibility Over Time in Arrhythmogenic Cardiomyopathy
The goal of this observational study is to learn whether adults with arrhythmogenic cardiomyopathy, an inherited heart muscle disease that can cause dangerous heart rhythms, remain eligible for a subcutaneous implantable…
- Trial name
- NCT07849764
- Testing
- Subcutaneous ICD ECG screening
- Where
- Brazil
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Cardiopulmonary Resuscitation, Education
Efficacy of Online Real-time CPR Training
The purpose of this study is to evaluate the effectiveness of a new online real-time quality measurement and feedback video-based CPR training program.
- Trial name
- NCT04656405
- Testing
- Online real-time quality measurement and feedback video-based CPR training, Online real-time feedback video-based CPR training without quality measurement, Conventional CPR training
- Where
- South Korea
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Physical Fitness, Musculoskeletal Health
Physical Fitness Assessment in Professional and Amateur E-Sports Players
The aim of this observational cross-sectional study is to compare the physical fitness characteristics of professional and amateur e-sports players and to determine whether differences exist between the two groups in terms of…
- Conditions
- Physical Fitness, Musculoskeletal Health, Sedentary Behavior, E-Athletes
- Trial name
- NCT07453316
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Istinye University
Upper Limb Ischemia, Vascular Disease
Hand Acceleration Time Assessment With Ultrasound Doppler
Chronic upper limb ischemia syndrome is uncommon compared to lower limb ischemia, with several potential causes (e.g., arteriosclerosis, compressive syndromes, arteritis, connective tissue diseases, trauma, and thrombosis).
- Trial name
- HAT (NCT05977725)
- Testing
- Hand Doppler Ultrasound
- Where
- Spain
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Hospital Universitari de Bellvitge
Pain, Inflammatory
First Time in Human Study Evaluating the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics and the Effect of Food of Single Assending Doses of GSK1482160.
This is a first-time-in-human study. The overall purpose of the study is to assess whether the drug is safe and well tolerated after single, increasing doses.
- Trial name
- NCT00849134
- Where
- United Kingdom
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Respiratory Tract Infection, Infections, Bacterial
A Three-Part Study Of GSK580416 In Healthy Subjects
Studies for GSK580416 have been completed in rats and dogs. The main toxic effects seen in animals affected the digestive system and blood cells. Study OPS106400 will be the first administration of GSK580416 in humans.
- Trial name
- NCT00427141
- Testing
- GSK580416
- Where
- Australia
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Obesity
Weight Loss In Obese Subjects Taking Either GW869682 Or Placebo 3 Times Per Day For 12 Weeks
GW869682 causes glucose to be excreted in the urine. The purpose of this study is to see whether enough calories from glucose are excreted in the urine to cause weight loss.
- Trial name
- NCT00297180
- Testing
- GW869682
- Where
- 3 sites in United States
- Volunteers
- 136 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Physician Communication
Effect of AIDET on Physician-Patient Communication
Patient satisfaction is an important aspect of care and is gaining increasing importance as a measure of Healthcare quality. Tools for improving physician-patient communication are available but have not yet been tested in the…
- Trial name
- AIDET (NCT01947400)
- Testing
- Hospitalists
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- University of Florida
Cardiometabolic Health Indicators, Child Health
Non-Invasive Assessment of Early Health Determinants in Children and Adolescents
LONGEVITY-NEXT is a single-center, non-profit observational study designed to assess early non-invasive determinants of cardiometabolic, functional, behavioral, and environmental health in children and adolescents aged 6 to 17…
- Trial name
- LONGEVITY-NEXT (NCT07861516)
- Where
- Italy
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Health Adults, Patients With Traumatic Hand Injury
Ultrasonography-guided Real-time Modular Systems for Hand Therapy
This study aimed to develop an ultrasonography-guided real-time modular system and try to apply it to clinical hand therapy using. This study was divided into two parts. The first part is an observational study design.
- Trial name
- NCT06189235
- Testing
- Biofeedback training
- Where
- Taiwan
- Volunteers
- 149 people, healthy volunteers welcome
- Sponsor
- National Cheng-Kung University Hospital
Oedema, Pulmonary
A First Time in Human Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of GSK2798745 in Healthy Subjects and Stable Heart Failure Patients
This study is the first administration of GSK2798745 in humans. This will be a sponsor un-blinded, placebo-controlled study to investigate the safety, tolerability, pharmacokinetics (PK), and pharmacodynamics (PD) of GSK2798745…
- Trial name
- NCT02119260
- Testing
- GSK2798745 solution, GSK2798745 suspension, GSK2798745 capsule
- Where
- 2 sites in United Kingdom
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Stroke, Psychological Well-Being
Aspirational Rehabilitation Coaching for Holistic Health (ARCH): A Pilot Pre-Post Experimental Study
The ARCH programme is a novel, strength-based, dyadic, multicomponent psychosocial intervention that blends together psychoeducation, psychosocial support and self-compassion practices to aid first-time stroke survivors and their…
- Conditions
- Stroke, Psychological Well-Being, Psychosocial Functioning
- Trial name
- NCT06596551
- Testing
- Pre-Post ARCH Intervention
- Where
- Singapore
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Nanyang Technological University
The Individual Must be 18 Years of Age or Older, The Individual Must be Willing to Participate in the Study
The Relationship Between the ASA Score Determined by Operating Room Nurses and Intubation Duration
The objective of this study is to The objective of this study was to ascertain the extent to which operating room nurses assign ASA scores and to assess the reliability of these scores in predicting significant risk factors…
- Trial name
- NCT07382895
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Zonguldak Bulent Ecevit University
Allergic Conjunctivitis
Evaluation of Efficacy of Ophthalmic Solution in Induced Allergic Conjunctivitis
The purpose of this study is to establish the efficacy of R89674 0.25% ophthalmic solution compared with placebo in alleviating the signs and symptoms of conjunctival allergen challenge-induced allergic conjunctivitis
- Trial name
- NCT00244543
- Testing
- R89674 (generic name not yet established)
- Where
- United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Vistakon Pharmaceuticals