Clinical trials: Investigation Time
Healthy Male Volunteers
First-time-in-man, to Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of BP1.5375
Phase I Single Ascending Dose (Part 1), phase IIa Proof Of Concept (Part 2)
- Trial name
- NCT01965301
- Testing
- BP1.5375 suspension, Diphenhydramine
- Where
- Netherlands
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Bioprojet
Healthy
Evaluation of Correct PEP Use With the Time
Healthy subjects will be trained to used correctly a positive expiratory pressure device. The aim of the study is to evaluate te reproductibility of the correct used of the device after training
- Trial name
- NCT02031926
- Testing
- Positive expiratory pressure
- Where
- Belgium
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
HIV Infections
Evaluation of the Safety, Tolerability and Pharmacokinetics (PK) of GSK3732394 First-Time-in-Human (FTIH) Study
This is a phase 1, 2-part, double-blind (sponsor-unblinded), randomized, placebo-controlled, FTIH study, that includes both single-ascending and multiple-ascending dose phase to assess the safety, tolerability, and…
- Trial name
- NCT03984812
- Testing
- GSK3732394
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- ViiV Healthcare
Thyroid Eye Disease, TED
Multi-modal Medical Images for Extraocular Muscle Fibrosis Assessment
The purpose of this study was to evaluate the elasticity of the extraocular muscles in different stages of thyroid eye disease and to examine the correlation of MRI parameters (native T1 value and ECV) and elasticity for the…
- Trial name
- NCT07056114
- Testing
- The patients with active or inactive TED
- Where
- China
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Tianjin Eye Hospital
Healthy
Evaluation of Vascular Pathology With 3D, Time-Resolved Phase Contrast Magnetic Resonance Imaging (MRI)
Aortic coarctation is a relatively common cardiovascular condition with high associated mortality if not treated. Even with successful repair, however, close follow up is needed as late complications can result in significant…
- Trial name
- NCT00722904
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Pressure Injury, Risk Assessment
Positioning Duration and Pressure Injury Risk
This research aims to investigate the effect of positioning times on the risk of pressure injury in critically ill patients.
- Trial name
- PIP-ICU (NCT07355439)
- Testing
- Position Change - 1 Hour, Position Change - 2 Hours
- Where
- Turkey (Türkiye)
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- SEMA ŞAHİNER
Cystic Fibrosis, Bronchiectasis
Reaction Time and Postural Control in Individuals With Cystic Fibrosis and Bronchiectasis
The aim of this study is to evaluate the reaction time and postural control and to investigate the relationship between reaction time, exercise capacity, muscle oxygenation and balance in children with cystic fibrosis (CF) and…
- Trial name
- NCT03902236
- Testing
- Reaction Time and Postural Control, Muscle oxygenation, Exercise capacity
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Irreversible Pulpitis, Partial Pulpotomy
Evaluation of Hemostasis Time on Partial Pulpotomy in Teeth With Clinical Signs Indicative of Irreversible Pulpitis
The aim of this prospective study is to investigate the influence of time taken to achieve hemostasis on outcome of partial pulpotomy in teeth with clinical signs indicative of irreversible pulpitis. OBJECTIVE:- 1.
- Trial name
- NCT06768567
- Testing
- effect of hemostasis time on outcome of partial pulpotomy in teeth with clinical signs indicative of irreversible pulpitis.
- Where
- India
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Post-induction Hypotension
Evaluation of the Relation Between Patient Fasting Time and the Occurrence of PIH (Post Induction Hypotension)
This monocentre prospective trial aims to evaluate the relationship between fasting time and the occurence of PIH (post-induction hypotension).
- Trial name
- NCT07785635
- Where
- Czechia
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University Hospital Ostrava
Healthy
Study Evaluating the Safety and Ability to Produce Immune Response of Prevenar and Meningitec Given at the Same Time
The purpose of this study is to evaluate the safety and immunogenicity of concomitant Prevenar and Meningitec compared to Prevenar alone and Meningitec alone when used as part of the routine vaccination series in healthy infants
- Trial name
- NCT00581035
- Testing
- Prevenar and Meningitec, Prevenar, Meningitec
- Volunteers
- 712 people, healthy volunteers welcome
- Sponsor
- Wyeth is now a wholly owned subsidiary of Pfizer
Non-carious Cervical Lesions
Evaluation of the Reduced Dentin Etching Time Using Universal Adhesives in the Quality of Cervical Lesions Restorations
The aim of this study will be to evaluate the effect of reduced dentin etching time on the 6- and 12-months clinical performance of two universal adhesive systems used as etch-and-rinse application mode in non-carious cervical…
- Trial name
- NCT06465849
- Testing
- Dentin Etching time for 5 seconds, Scotchbond Universal Plus; 3M, Gluma Universal Bond; Kulzer
- Where
- Chile
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Universidad de los Andes, Chile
Human Papillomavirus Virus
Observational Follow up of Prior HPV Vaccinees
HPV vaccines have been included in the national immunisation schedule since 2008, firstly as the Cervarix vaccine which protects against two HPV types and in 2012 as the Gardasil vaccine which offers protection against a further…
- Trial name
- HPVfollowup (NCT02811068)
- Testing
- venepuncture
- Where
- 2 sites in United Kingdom
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- Public Health England
Gastro-Intestinal Disorder
Evaluation of the Impact of a Forward Viewing Scope at Time of ERCP
This study will be a prospective, tandem-designed study to determine the proportion of clinically significant missed lesions when using a side- or oblique-viewing endoscope as compared to the standard forward-viewing endoscope.
- Trial name
- NCT05627882
- Testing
- Forward viewing endoscope
- Where
- United States
- Volunteers
- 163 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Infantile Colic
Evaluation of Safety and Efficacy of New Infant Formula in Infantile Colic
The study is conducted to examine the safety and efficacy of a new infant formula and its effects on the gastrointestinal tolerance in infants suffering from colic.
- Trial name
- Coco (NCT01721850)
- Testing
- control formula, intervention formula 1, intervention formula 2
- Where
- 18 sites in Germany, Italy
- Volunteers
- 169 people, healthy volunteers welcome
- Sponsor
- HiPP GmbH & Co. Vertrieb KG
The Effect of Local Aplication of Cayanoacrylate Tissue Adhesives on Improving the Healing
Cyanoacrylate Tissue Adhesives Versus Silk Suture at the Palatal Donor Site of Sub Epithelial Connective Tissue Graft
Subepithelial connective tissue grafts (CTG) are considered the gold standard procedure with proven clinical success when it comes to gingival augmentation aims to to improve periodontal health, which can enhance the long-term…
- Trial name
- NCT04780360
- Testing
- Cayanoacrylate tissue adhesives, Silk suture
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cairo University
Healthy Adult
This Study Evaluates Skin Response Following Application of a Collagen-based Material in Healthy Adult Volunteers Using a Standardized Skin Prick Test. Skin Responses Will be Assessed at Multiple Time Points Following Application, and the Study is Intended to Evaluate Dermal Safety.
This study evaluates the allergic (immunogenic) response following application of a collagen-based material in healthy adult volunteers using a standardized skin prick test.
- Trial name
- SPT (NCT07473674)
- Testing
- Collagen Matrix Skin Prick Test Device
- Where
- United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- SerenaGroup, Inc.
Healthy
A Study In Healthy People To Evaluate Safety, Toleration And Time Course Of Plasma Concentration Of Multiple Oral Doses Of PF-04895162
The purpose of this study in healthy people is to investigate safety, toleration and time course of plasma concentration of PF-04895162, following multiple oral doses for 14 days.
- Trial name
- NCT01691274
- Testing
- PF-04895162
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Pfizer
Meibomian Gland Dysfunction, Dry Eye
Evaluating Impact of Systane iLux on Dryness Symptoms and Wearing Time in Contact Lens Users
To evaluate dry eye symptoms and contact lens wearing times after a single iLux treatment by evaluating change from baseline in OSDI scores, subjective CLDEQ8 and CL wearing time questionnaires, and meibomian gland secretion…
- Trial name
- NCT05306561
- Testing
- Systane iLux thermal pulsation treatment
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Periman Eye Institute
Inflammatory Bowel Disease, Ulcerative Colitis
Assessment of Colonic Permeability by Confocal Laser Endomicroscopy
The purpose of this study is to evaluate the efficacy of confocal laser endomicroscopy in assessment of colonic permeability against conventional sugar absorption test.
- Conditions
- Inflammatory Bowel Disease, Ulcerative Colitis, Irritable Bowel Syndrome
- Trial name
- NCT00883077
- Where
- China
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Shandong University
Brain Tumor
Real-time Assessment of Frameless Intrafraction Motion
The purpose of this study is to assess the ability of a modified thermoplastic mask system in keeping an individual head stationary for a predefined amount of time.
- Trial name
- NCT01202539
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Oregon Health and Science University