Clinical trials: Investigation Time
Hypoxia
Evaluation of RDS MultiSense® in Desaturation Analysis in Healthy Volunteers
In this clinical study, the investigators will compare vital parameters measurements obtained using continuous data from reference monitors and continuous wireless MultiSense® monitoring patch in 30 healthy volunteers under…
- Trial name
- HYPO (NCT05044585)
- Testing
- Remote Automated Monitoring System
- Where
- France
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- IHU Strasbourg
Obesity & Overweight, Bariatric Surgery
Time-Restricted Eating After Bariatric Surgery
This study aims to compare the effects of time-restricted eating (TRE, 16/8) in adults with obesity who have and have not undergone bariatric surgery (BS).
- Conditions
- Obesity & Overweight, Bariatric Surgery, Weight Regain, Weight Regain Post Bariatric Surgery
- Trial name
- NCT07672821
- Testing
- Time-Restricted Eating (16:8)
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Medipol University
Diabetes Mellitus, Type 2
Time in Glucose Hospital Target
Inpatient management of glycemia in people with diabetes has been inadequately studied. Previous randomized trials of intensive insulin therapy in the hospital setting resulted in excessive hypoglycemia.
- Trial name
- TIGHT (NCT05135676)
- Testing
- Blinded CGM, real-time CGM
- Where
- 6 sites in United States
- Volunteers
- 166 people
- Sponsor
- Jaeb Center for Health Research
Ileus, Gastro-Intestinal Disorder
A Study to Evaluate LB1148 for Return of Bowel Function in Subjects Undergoing Bowel Resection
The purpose of this study is to evaluate the safety and efficacy of LB1148 in subjects undergoing planned bowel resection.
- Trial name
- INTEGRITY (NCT05470387)
- Testing
- LB1148
- Where
- 23 sites in United States
- Volunteers
- 23 people
- Sponsor
- Palisade Bio
Colitis, Ulcerative
A First Time in Human Study to Evaluate the Safety and Tolerability of GSK4381406 in Healthy Participants
This is a 3-part First Time in Human (FTIH) study to evaluate the safety, tolerability, and pharmacokinetics (PK) profile of GSK4381406 following administration of single ascending doses (Part 1), repeat ascending doses (Part 2)…
- Trial name
- NCT05999708
- Testing
- GSK4381406, Indomethacin
- Where
- United Kingdom
- Volunteers
- healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Brain
Triage Radiology Imaging Assessment for Greater Effectiveness
The aim of the trial is to understand whether a computerised tool designed to quickly spot problems in brain scans (MIDI) can help doctors diagnose cases faster.
- Trial name
- TRIAGE (NCT07671664)
- Testing
- MIDI
- Volunteers
- 100,800 people
- Sponsor
- King's College London
Estrogen Receptor-positive Breast Cancer, Gastrinoma
Pharmacokinetically Guided Everolimus in Patients With Breast Cancer, Pancreatic Neuroendocrine Tumors, or Kidney Cancer
This phase II trial studies how well real-time pharmacokinetic therapeutic drug monitoring works in preventing stomatitis from developing in patients with hormone receptor positive breast cancer, pancreatic neuroendocrine tumors…
- Conditions
- Estrogen Receptor-positive Breast Cancer, Gastrinoma, Glucagonoma, HER2-negative Breast Cancer
- Trial name
- NCT02273752
- Testing
- Everolimus
- Where
- 2 sites in United States
- Volunteers
- 2 people
- Sponsor
- Emory University
Central Abdominal Bulging
Extension Study to Evaluate the Post-Treatment Safety and Duration of Clinical Effect of LIPO-202
LIPO-202-CL-23 is a follow-on study to evaluate the post-treatment safety and duration of clinical effect of LIPO-202 in subjects that completed either the LIPO-202-CL-18 (NCT02397499) or LIPO-202-CL-19 (NCT02398188).
- Trial name
- NCT02483533
- Testing
- LIPO-202
- Volunteers
- 100 people
- Sponsor
- Evofem Inc.
Arrhythmias, Cardiac
RECORD-VP: Real-time Evaluation of Cardiac Outpatient Recording Device With VitalPatch RTM
The primary purpose of this study is to evaluate performance and safety of the VitalConnect Platform when used for mobile cardiac telemetry (MCT) or as an independent diagnostic testing facility (IDTF) system during activities of…
- Trial name
- NCT04556240
- Testing
- VitalConnect Platform
- Where
- United States
- Sponsor
- VitalConnect Inc.
Anaemia
Anemia Studies in Chronic Kidney Disease (CKD): Erythropoiesis Via a Novel Prolyl Hydroxylase Inhibitor (PHI) Daprodustat-Three-times Weekly Dosing in Dialysis (ASCEND-TD)
This Phase 3 study in hemodialysis-dependent subjects with anemia will evaluate the efficacy and safety of daprodustat administered three-times weekly compared to epoetin alfa, the current standard of care.
- Trial name
- NCT03400033
- Testing
- Daprodustat tablets, Epoetin alfa vials, Saline vials or bags
- Where
- 91 sites in United States, Argentina and 11 more
- Volunteers
- 407 people
- Sponsor
- GlaxoSmithKline
Lung Cancer
Assessment of Diagnostic Yield Using a Robotic Navigational Bronchoscopy System With CBCT
The aim of this research study is to evaluate the effectiveness of the ION endoluminal system at reaching and obtaining biopsies from lung nodules when used in combination with 3-dimensional imaging such as CT scans.
- Trial name
- NCT06084208
- Testing
- Biopsy with the Robotic- Ion Endoluminal System with Adjunct Real-time Imaging
- Where
- Netherlands
- Volunteers
- 132 people
- Sponsor
- Intuitive Surgical
Infertility, Infertility, Female
Aftificial Inteligence in Assisted Reproductive Techniques to Assess Oocyte Quality and Embryo Ploidy
The assisted reproduction success rate is affected by several factors including the age of the women, oocyte quality and maturation state, as well as sperm quality.
- Conditions
- Infertility, Infertility, Female, Infertility, Male, Infertility Unexplained
- Trial name
- SMARTAI (NCT06539104)
- Testing
- arteficial inteligence evaluation of oocyte and embryo development
- Where
- 4 sites in Czechia
- Volunteers
- 1,000 people
- Sponsor
- Charles University, Czech Republic
Pharyngitis
APC-231 Once a Day (QD) for 7 Days vs. Penicillin Taken Four Times a Day (QID) in Pediatric Patients With Strep Throat
The purpose of this study is to evaluate the efficacy and safety of APC-231 QD for 7 days in the bacteriological outcome at the Test of Cure Visit.
- Trial name
- NCT00100126
- Testing
- Amoxicillin Pulsatile Release Multiparticluate Sprinkle
- Where
- 2 sites in United States
- Volunteers
- 500 people
- Sponsor
- Advancis Pharmaceutical Corporation
Critical Illness, Malnutrition
Association Between Malnutrition and Clinical Outcomes in the Intensive Care Unit
Previous studies have demonstrated the direct associations between malnutrition and hospital mortality as well as the length of stay in critically ill patients.
- Trial name
- NCT03213899
- Volunteers
- 503 people
- Sponsor
- JurongHealth
Direct Costs Excluding Capital Equipment Purchase, Operator (Surgeon) Completed Questionnaire
Prostate Vaporization Techniques in Canadian Hospital
Kingston General Hospital is committed to upgrading the surgical treatment platform for benign prostate surgery. Vaporization Surgery, either laser-vaporization or electo-vaporization is becoming a "standard" of therapy for…
- Conditions
- Direct Costs Excluding Capital Equipment Purchase, Operator (Surgeon) Completed Questionnaire, Operative Parameters (Time, Bleeding Etc), Complications (Post-op Retention, Bleeding, Re-admission to Hospital, Infection Etc)
- Trial name
- NCT03495258
- Testing
- Clarion Evolve Laser Vaporization System, Olympus TURis Plasma Vaporization
- Where
- Canada
- Volunteers
- 55 people
- Sponsor
- Queen's University
Bone Lesion, Bone Tumor
Augmented Reality Navigation System (Endosight) for the Guidance of Bone Biopsy
The goal of this clinical study is to evaluate the duration of the procedure, the precision (distance between the needle tip and the centre of the target), and the safety of endosight system in the guidance for bone biopsies.
- Conditions
- Bone Lesion, Bone Tumor, Bone Infection
- Trial name
- NCT05732558
- Testing
- 8 Patients who were prescribed a CT-guided percutaneous bone biopsy, performed with the aid of endosight navigation system
- Where
- Italy
- Volunteers
- 16 people
- Sponsor
- R.A.W. - S.R.L.
Ligament; Laxity
Evaluation of Anterior Tibial Translation of the Knee in Healthy Women, at Two Times of the Menstrual Cycle, on Hormonal Contraceptives or Not (FLEX)
Women's participation in sports at all levels has been increasing in recent decades. Many individual and team sports are at risk of anterior cruciate ligament (ACL) injury.
- Trial name
- FLEX (NCT05177549)
- Testing
- Bilateral knee examination with Lachmeter®
- Where
- France
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Nice
Hallux Valgus, Hallux Rigidus
Comparison of Different Tourniquet Release Times in Bunion Surgery
Patients listed for hallux valgus/hallux rigidus correction surgery will be randomised to one of two treatment groups. Group 1 (standard care) will have the calf tourniquet released after wound closure.
- Trial name
- NCT03616847
- Testing
- Standard care, Tourniquet release
- Where
- United Kingdom
- Volunteers
- 80 people
- Sponsor
- Golden Jubilee National Hospital
Intracranial Hypertension, Traumatic Brain Injury
Intracranial PrEssure Time dOse (ImPETO)
The new Integra CereLink ICP monitor integrate the possibility of recording and displaying continuously the AUC (Pressure Time Dose, PTD) and other ICP derived variables and provide the possibility of evaluating the utility of…
- Conditions
- Intracranial Hypertension, Traumatic Brain Injury, Subarachnoid Hemorrhage, Intracranial Hemorrhages
- Trial name
- ImPETO (NCT04459806)
- Testing
- intracranial pressure monitoring
- Where
- Italy
- Volunteers
- 250 people
- Sponsor
- University of Milano Bicocca
Evaluate and Compare Between Excision and Primary Closure Procedure and Rhomboid Flap Technique for the Treatment of Pilonidal Sinus, Duration of Operation,
Rhomboid Flap Versus Primary Closure After Excision of Sacrococcygeal Pilonidal Sinus. (A Prospective Randomized Study)
To evaluate and compare between excision with primary closure of wound and excision with Rhomboid flap reconstruction in the treatment of pilonidal sinus as regard duration of operation, healing time, hospital stay, complications…
- Trial name
- non (NCT01223599)
- Volunteers
- 140 people
- Sponsor
- Mansoura University
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.