Clinical trials: Investigation Time, open to volunteers
Carbapenemase-Producing Enterobacterales (CPE) Colonization
Impact of Implementing a Rapid PCR-based Algorithm for Carbapenemase-producing Enterobacterales (CPE) and Infection Control Bundle in a Tertiary Hospital
Purpose: Carbapenemase-producing Enterobacterales (CPE) are a growing cause of healthcare-associated infections, linked to high morbidity, mortality, and cost.
- Trial name
- NCT07397416
- Testing
- Rapid PCR-based algorithm for CPE detection
- Volunteers
- 800 people
- Sponsor
- Hospital Italiano de Buenos Aires
Abdominal Injuries, Alcohol Intoxication
Alcohol, Psychoactive Drugs, Analgesics and Evaluation in Penetrating Abdominal Trauma
This prospective observational study aims to evaluate whether alcohol consumption, psychoactive drug use, or prior administration of analgesics affects the clinical evaluation and surgical decision-making process in patients with…
- Conditions
- Abdominal Injuries, Alcohol Intoxication, Substance-related Disorders, Penetrating Abdominal Trauma
- Trial name
- DIRECT (NCT07330349)
- Testing
- Alcohol consumption, Psychoactive substance use, Analgesic administration
- Where
- 2 sites in Colombia
- Volunteers
- 363 people
- Sponsor
- Fundacion Clinica Valle del Lili
Mental Health Help-Seeking, Mental Health Difficulties
Changes in Children and Young People's Well-being and Parental Stress While Seeking Help at CAMHS in Denmark. How Does Waiting Affect CYP and Their Parents Before, During and After CAMHS Assessments.
Questionnaire-based longitudinal cohort study. Families on the waiting list for an assessment with Child and Adolescent Mental Health Services (CAMHS) are invited to complete questionnaires including the Parental Stress Scale…
- Conditions
- Mental Health Help-Seeking, Mental Health Difficulties, Help-Seeking Behavior, Waiting Times, Patient Pathways, Effect of Lifestyle-related, Clinical and Demographic Parameters on Outcomes
- Trial name
- NCT07553104
- Where
- Denmark
- Volunteers
- 200 people
- Sponsor
- Aalborg University Hospital
Left Ventricular Systolic Dysfunction, Heart Failure (Pediatric)
A Study to Learn More About How Safe Finerenone is, When it is Taken for a Longer Time With Standard Treatment, in Children and Young Adults With Heart Failure and Left Ventricular Systolic Dysfunction
Researchers are looking for a better way to treat children and young adults who have heart failure with left ventricular systolic dysfunction (LVSD).
- Trial name
- FIORELLO (NCT07192952)
- Testing
- Finerenone (Kerendia, BAY94-8862)
- Where
- 132 sites in United States, Argentina and 21 more
- Volunteers
- 117 people
- Sponsor
- Bayer
Chest Pain, Stroke Acute
Evaluation and Optimization of Telephone Triage Using Artificial Intelligence (AI) Models for the Detection of Demands for Time-dependent Pathology at the Emergency and Urgent Care Coordination Center (CCUE).
Improving Telephone Triage in Emergency Calls with AI The Coordinating Centre for Urgencies and Emergencies in Andalusia (CCUE) handles thousands of calls every day.
- Conditions
- Chest Pain, Stroke Acute, Respiratory Failure, Cardiac Arrest (CA)
- Trial name
- TrIAje Project (NCT07247669)
- Where
- Spain
- Volunteers
- 5,000,000 people
- Sponsor
- Centro de Emergencias Sanitarias 061 Andalucía
Neurodevelopment, Child Growth
Building Opportunities for Nurturing Care to Enhance Child Development in Eastern and Southern Africa
The goal of this randomized controlled trial is to adapt and test a package of interventions to provide nurturing care for children aged 0-2 years in three countries (Botswana, Kenya, Zimbabwe).
- Trial name
- BONDS (NCT07430826)
- Testing
- Friendship Bench, Infant and Young Child Feeding (IYCF) Curriculum, Play-Based Curriculum
- Volunteers
- 1,260 people, healthy volunteers welcome
- Sponsor
- University of Washington
Cardiac Arrest
Recognition of a Cardiac Arrest Within the EMS
This study aims to evaluate the average time taken by the Medical Regulation Assistants (MRA) to detect a cardiac arrest during the call to the EMS as well as the factors influencing this delay.
- Trial name
- ACR90 (NCT05523999)
- Testing
- Time elapsed between the taking in charge of the call and the recognition of a cardiac arrest by the MRA
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Hôpital NOVO
Respiratory Tract Infections (RTI)
Real-Time Mass Spectrometry Breath Analysis for the Investigation of Respiratory Tract Infections
Lower respiratory tract infections (LRTIs) remain a major global health burden, with diagnosis often challenged by clinical heterogeneity, overlapping symptoms, difficulty in obtaining quality biological specimens and limitations…
- Trial name
- Respire (NCT07685275)
- Testing
- Breath analysis
- Where
- 3 sites in France
- Volunteers
- 450 people
- Sponsor
- Hopital Foch
ESCAPE Intervention+NRT, quitSTART Intervention+NRT
Enhancing Smoking Cessation for African American People Everywhere
The present study aims to investigate the efficacy of an mHealth smoking cessation and HIV disease management intervention among a nationally representative sample of African America/Black (hereafter refer to as Black) persons…
- Conditions
- ESCAPE Intervention+NRT, quitSTART Intervention+NRT, CTRL+NRT
- Trial name
- ESCAPE (NCT07024992)
- Testing
- ESCAPE app + NRT, quiSTART app + NRT, Control (CTRL)
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- University of Houston
Rehabilitation, Elderly Person
Evaluation of the Concordance of Five Times Sit To Stand Results Between a Physical Consultation and a Teleconsultation
This study concerns elderly person aged more than 65 years with autonomous mobility. It is a multicentric randomized trial in two arms : Arm one : remote consultation then physical consultation Arm two : physical consultation…
- Conditions
- Rehabilitation, Elderly Person, Teleconsultation
- Trial name
- TELETEST (NCT06365177)
- Testing
- Physical consultation, Teleconsultation
- Where
- 2 sites in France
- Volunteers
- 108 people
- Sponsor
- University Hospital, Brest
Acute Pain, Post Operative Analgesia
Analgesic Efficacy of Combined PECS II and PIP Block Versus Thoracic Paravertebral Block Post-Mastectomy
Postoperative pain management is crucial for patients undergoing mastectomy for breast cancer. Regional analgesia techniques, such as the Thoracic Paravertebral Block (TPVB), are commonly used to reduce pain and opioid…
- Conditions
- Acute Pain, Post Operative Analgesia, Post Operative Pain, Acute, Breast Cancer
- Trial name
- PECS-TPVB (NCT07738770)
- Testing
- Combined PECS II and Superficial PIP Block, Thoracic paravertebral block (TPVB)
- Where
- Indonesia
- Volunteers
- 72 people
- Sponsor
- Dharmais National Cancer Center Hospital
Time of the Crowning of the Fetal Head, Levator Ani Avulsion
The Effect of Crowning Time on Levator Ani Muscle Avulsion
Levator ani muscle is one of the main components of perineal muscles and plays a crucial role in urinary continence and pelvic organ support.
- Conditions
- Time of the Crowning of the Fetal Head, Levator Ani Avulsion, Labor Delivery, Postpartum
- Trial name
- NCT07210788
- Where
- Canada
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Université de Sherbrooke
Monitor Adverse Events
Evaluation of Screen Time and Digital Media on ADHD
1. Assess how different types of digital media influence inattention, impulsivity, and hyperactivity in children with ADHD. 2. Analyze the role of screen time duration, content type, parental supervision, and socioeconomic status…
- Trial name
- ADHD (NCT06934746)
- Testing
- DSM-5 criteria.
- Volunteers
- 130 people
- Sponsor
- Assiut University
Biliary Stricture
Real-Time Cholangioscopy Artificial Intelligence Evaluation of Biliary Strictures
The purpose of this study is to demonstrate the feasibility and validity of a previously developed peroral cholangioscopy (POC) convolutional neural network (CNN) to determine the etiology of biliary strictures when used in…
- Trial name
- NCT05779436
- Where
- 2 sites in United States
- Volunteers
- 100 people
- Sponsor
- Mayo Clinic
Alcohol Misuse, Homeless
Efficacy of a Smartphone-Based JITAI to Reduce Drinking Among Adults Experiencing Homelessness
Approximately 1 out of every 3 adults experiencing homelessness has a current alcohol use disorder (AUD). Alcohol use plays a central role in increased morbidity and mortality in this population, with some studies suggesting it…
- Trial name
- SmartT_A (NCT06821295)
- Testing
- Smart-T Alcohol, Usual Care
- Where
- United States
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma
Percutaneous Coronary Intervention, Dual Antiplatelet Therapy
Efficacy and Safety of Short Duration of DAPT After GENOSS® DES Implantation in Patients with Coronary Artery Disease
The objective of study is to evaluate the efficacy and safety of short duration of DAPT after GENOSS® DES Implantation in patients with coronary artery disease.
- Trial name
- DAPTShort (NCT06075420)
- Where
- South Korea
- Volunteers
- 1,000 people
- Sponsor
- Genoss Co., Ltd.
Spinal Anesthesia Duration
Comparative Analysis of Intraoperative Effect Dexmedetomidine and Fentanyl as an Adjuvant to Heavy Bupivacaine in Spinal Anaesthesia in Lower Limb Orthopedic Surgeries to Evaluate the Hemodynamic Stability and Onset and Duration of Motor Block of Using Intrathecal Dexmedetomidine and Fentanyl
Spinal anesthesia is the most widely employed procedure for lower limb orthopedic operations, as it is very cost-effective and simple to apply.
- Trial name
- NCT07078201
- Testing
- Dexmedetomidine, fentanyl
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Nashwa Ahmed
Spasticity, Stroke
Early Botulinum Toxin for Muscle Stiffness Reduction in First-Time Stroke Patients: Improving Recovery and Independence
This study examines the early use of botulinum toxin in patients recovering from their first stroke to help reduce muscle stiffness and improve mobility.
- Conditions
- Spasticity, Stroke, Neurological Rehabilitation
- Trial name
- EARLY BOT-SPAS (NCT06811142)
- Testing
- Botulinum Toxin Type A (BoNT-A)
- Where
- Mexico
- Volunteers
- 200 people
- Sponsor
- Instituto Mexicano del Seguro Social
Vaginal Odor
Safety Assessment of pH-D New Instant Rinse for One Time Use
Demonstrate the safety characteristics of new formulations of pH-D foam wash and instant rinse
- Trial name
- NCT07802483
- Testing
- Lactic Acid instant odor rinse, Boric Acid instant odor rinse
- Volunteers
- 90 people
- Sponsor
- pH-D Feminine Health LLC
Chronic Constipation, Slow Transit Constipation
MSOT and MRI for Non-invasive Assessment of Intestinal Transit Time in Children With Chronic Bowel Emptying Disorders
The project presented here is a monocentric clinical study conducted by the Pediatric Surgery and Pediatrics departments of the University Hospital Erlangen.
- Conditions
- Chronic Constipation, Slow Transit Constipation, Intestinal Transit Disorder, Hirschsprungs Disease
- Trial name
- NCT06911749
- Testing
- MSOT with ICG, MRI
- Where
- Germany
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Dr. med. Sonja Diez