Clinical trials: Ipsilateral Recurrence
Invasive Breast Cancer, Ipsilateral Recurrence
Sentinel Lymph Node Procedure in Ipsilateral Invasive Breast Cancer Relapse
Sentinel lymph node biopsy (SLNB) has become the standard procedure for staging of patients with clinically node-negative breast cancer.
- Conditions
- Invasive Breast Cancer, Ipsilateral Recurrence, Sentinel Lymph Node Biopsy
- Trial name
- FIGARO (NCT03630653)
- Testing
- Sentinel LN in breast cancer recurrence
- Where
- 9 sites in France
- Volunteers
- 50 people
- Sponsor
- Institut Cancerologie de l'Ouest
Breast Cancer, Tumor, Breast
Repeat Breast Conserving Surgery Followed by Daily Partial Breast Irradiation in Ipsilateral Breast
The standard treatment for participants whose cancer has returned after breast conserving surgery is radiation given twice daily (separated by at least 6 hours) for a total of 30 treatments.
- Trial name
- NCT06129747
- Testing
- Radiation Therapy
- Where
- 2 sites in United States
- Volunteers
- 55 people
- Sponsor
- Case Comprehensive Cancer Center
Deep Vein Thrombosis
Advanced Diagnostic Management of Suspected Recurrent Ipsilateral DVT With MRDTI
The Theia-study is a prospective, multicenter, single-arm management (cohort) study. Consecutive patients with clinically suspected acute, recurrent, ipsilateral, proximal deep vein thrombosis (DVT) of the leg, who fulfil all the…
- Trial name
- Theia (NCT02262052)
- Testing
- MRDTI
- Where
- 12 sites in Canada, Israel and 3 more
- Volunteers
- 305 people
- Sponsor
- Leiden University Medical Center
Mastectomy
Repeat Sentinel Lymph Node Biopsy in Ipsilateral Breast Tumor Recurrence
According to the standard treatment guidelines established until recently, in the case of ipsilateral breast tumor recurrence without systemic metastasis, salvage mastectomy or lumpectomy can be performed when either partial or…
- Trial name
- NCT04741737
- Testing
- reSLNB arm
- Where
- South Korea
- Volunteers
- 532 people
- Sponsor
- Gangnam Severance Hospital
Renal Cell Carcinoma, Robotic Surgical Procedures
Evaluation of the Safety of Reoperation for Ipsilateral Recurrent Tumors After Nephron-sparing Partial Nephrectomy
To evaluate the safety of reoperation in patients with renal tumors who have ipsilateral tumor recurrence after nephron-sparing partial nephrectomy.
- Trial name
- LiangAH (NCT06317207)
- Volunteers
- 15 people
- Sponsor
- The First Affiliated Hospital of Anhui Medical University
Breast Cancer, Unilateral
MIAMI Safe Surgery for Multiple Breast Cancers
Sometimes women have more than one breast cancer in the same breast at the same time. These women are usually offered a mastectomy (removal of that breast) and breast reconstruction.
- Trial name
- MIAMI (NCT03514654)
- Testing
- Mastectomy, Therapeutic Mammoplasty
- Where
- 7 sites in United Kingdom
- Volunteers
- 4 people
- Sponsor
- University College, London
Breast Cancer Recurrent
aPBI Re-irradiation
This study is to determine whether acute treatment-associated adverse events following breast re-irradiation with aPBI are acceptably low and to assess local control following breast re-irradiation with aPBI.
- Trial name
- REPEAT (NCT07612254)
- Testing
- Reirradiation
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Breast Cancer
Radiation OmisSion in PAtients With CLinically Node Negative Breast Cancer Undergoing Lumpectomy
To de-escalate radiation therapy in women with breast cancer.
- Trial name
- ROSALIE (NCT05866458)
- Where
- 27 sites in Australia, Canada
- Volunteers
- 352 people
- Sponsor
- Ontario Clinical Oncology Group (OCOG)
Breast Cancer
A Prospective Cohort Study Evaluating Risk of Local Recurrence Following Breast Conserving Surgery and Endocrine Therapy in Low Risk Luminal A Breast Cancer
This is a multicentre, single-arm prospective cohort study evaluating risk of ipsilateral breast tumour recurrence(IBTR) following breast conserving surgery (BCS) in a group of women postulated to be at low risk for recurrence.
- Trial name
- LUMINA (NCT01791829)
- Where
- 27 sites in Canada
- Volunteers
- 500 people
- Sponsor
- Ontario Clinical Oncology Group (OCOG)
Deep Vein Thrombosis
Ancillary Study of the ULTREC Project
The ULTREC research project is designed to assess the safety of a negative strategy relying on Colour Doppler Ultrasound (CDUS) for excluding the diagnosis of a new thrombosis.
- Trial name
- ULTRECAncillar (NCT05300139)
- Testing
- Color Doppler Ultrasound
- Where
- 12 sites in France
- Volunteers
- 18 people
- Sponsor
- Centre Hospitalier Intercommunal de Toulon La Seyne sur Mer
Recurrent Non-Small Cell Lung Carcinoma, Stage IIA Non-Small Cell Lung Carcinoma
Photodynamic Therapy During Surgery in Treating Patients With Non-small Cell Lung Cancer That Can Be Removed by Surgery
This phase I trial studies the side effects and best dose of photodynamic therapy during surgery in treating patients with non-small cell lung cancer that can be removed by surgery.
- Conditions
- Recurrent Non-Small Cell Lung Carcinoma, Stage IIA Non-Small Cell Lung Carcinoma, Stage IIB Non-Small Cell Lung Carcinoma, Stage IIIA Non-Small Cell Lung Cancer
- Trial name
- NCT01854684
- Testing
- Temoporfin, Therapeutic Conventional Surgery, Photodynamic Therapy
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Roswell Park Cancer Institute
Breast Cancer
Radiation Therapy in Treating Patients With Recurrent Breast Cancer
RATIONALE: Radiation therapy uses high-energy x-rays and other types of radiation to kill tumor cells. It is not yet known whether a single dose of radiation therapy is more effective than implant radiation therapy for 5 days in…
- Trial name
- NCT00945061
- Testing
- intracavitary balloon brachytherapy, intraoperative radiation therapy
- Where
- 3 sites in United States
- Volunteers
- 13 people
- Sponsor
- Case Comprehensive Cancer Center
Recurrent Breast Cancer
Reoperative Sentinel Lymph Node Biopsy in Patients With Recurrent Ipsilateral Breast Cancer
The goal of this observational study is to assess the effectiveness of sentinel lymph node biopsy as a treatment approach for patients with recurrent breast cancer on the same side as previous surgeries.
- Trial name
- RENATA (NCT06329089)
- Testing
- Reoperative Sentinel Lymph Node Biopsy
- Where
- Spain
- Volunteers
- 97 people
- Sponsor
- Hospital Clinic of Barcelona
Recurrent Breast Carcinoma, Ipsilateral Recurrence
Preoperative Partial Breast Reirradiation and Repeat Breast-conserving Surgery in Patients With Recurrent Breast Cancer: the REPEAT Trial
Over the past decades, interest in second breast-conserving therapy (BCT) has increased due to, among others, advancements in radiotherapy techniques.
- Trial name
- REPEAT (NCT06640881)
- Testing
- ablative single-dose PBI
- Where
- Netherlands
- Volunteers
- 25 people
- Sponsor
- Amsterdam UMC, location VUmc