Clinical trials: Irisin
Hypothyroidism
Effect of Exercise on Irisin Levels of Hypothyroid Rats
The aim of study was to evaluate the role of exercise on serum irisin levels in hypothyroid rats.
- Trial name
- NCT06699069
- Testing
- Control or Euthyroid group, Hypothyroid group, Hypothyroid group received exercise
- Where
- Pakistan
- Volunteers
- 30 people
- Sponsor
- Riphah International University
Obesity
NMES Plus Hypocaloric Diet: Body Composition, Cardiometabolic Markers, Irisin and Betatrophin in Women With Obesity
This randomized controlled trial evaluated whether adding localized neuromuscular electrical stimulation (NMES) to an individualized hypocaloric diet changes serum irisin and betatrophin (ANGPTL8) concentrations, body composition…
- Trial name
- NCT07675382
- Testing
- Hypocaloric Diet, Neuromuscular Electrical Stimulation (NMES)
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people
- Sponsor
- Firat University
Myocardial Infarction, Coronary Artery Disease
Serum Irisin in Myocardial Infraction and Following Percutaneous Coronary Intevention
The investigators aim to evaluate circulating irisin levels alterations in patients with acute myocardial infraction and in patients with coronary artery disease subjected to percutaneous coronary intervention.
- Trial name
- IRICARDIO (NCT02498431)
- Testing
- percutaneous coronary intervention, coronary angiography, Stent, Medronic Resolute Integrity
- Where
- Greece
- Volunteers
- 116 people
- Sponsor
- 424 General Military Hospital
Diabetic Patients
Omega 3 Fatty Acids on Serum Irisin and Sirtuin-1 in Type 2 Diabetic Mellitus Patients Treated With Glimepiride
study the effect of omega 3 fatty acids on blood glucose, lipids profile, serum Irisin and sirtuin-1 in type 2 diabetic mellitus patients treated with glimepiride.
- Trial name
- NCT03917940
- Testing
- Omega 3 fatty acids 1000 mg per day + glimepiride 2 mg or 3 mg oral, Glimepiride
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Damanhour University
Neuroinflammatory Diseases, Multiple Sclerosis
FIT-ATOMIC Exercise Feasibility Trial
This multi-center, randomized controlled feasibility trial will assess a 20-week home-based exercise intervention in youth with Multiple Sclerosis (MS).
- Trial name
- FIT-ATOMIC (NCT06870968)
- Testing
- Exercise Training, Mobility and Flexibility Training
- Where
- 4 sites in United States, Canada
- Volunteers
- 40 people
- Sponsor
- The Hospital for Sick Children
Breast Cancer, Colon Cancer
The Effect of Aerobic Exercise on Selective Biomarkers of Patients With Cancer
This study is a single-blinded, prospective, controlled trial aiming to evaluate the effect of supervised aerobic exercise on adipokine and myokine biomarkers in patients with breast or colon cancer during their systemic…
- Conditions
- Breast Cancer, Colon Cancer, Chemotherapy Effect
- Trial name
- NCT07048847
- Testing
- Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people
- Sponsor
- Izmir Bakircay University
Cognitive Function
Resistance Training on Growth Factors
The goal of this clinial trial study is to explore the effect of high or low intensity resistance training (LIRT) under similar training volume on change in serum levels of BDNF, IGF-1, VEGF, irisin, and plasma Hcy in young…
- Trial name
- NCT06114550
- Testing
- High intensity resistance training, Low intensity resistance training
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Air Force Military Medical University, China
Insulin Resistance, Diabetes Mellitus Type 2
Insulin Sensitivity, Irisin and Adipokines as Outcome Parameters in Patients Undergoing Cardiac Surgery
BACKGROUND: Surgical injury and inflammation provoke a stereotypical stress response. Insulin resistance plays an intriguing role in these metabolic alterations and depends on the intensity of injury.
- Conditions
- Insulin Resistance, Diabetes Mellitus Type 2, Other Functional Disturbances Following Cardiac Surgery
- Trial name
- NCT02258698
- Testing
- Cardiac surgery
- Where
- Switzerland
- Volunteers
- 348 people
- Sponsor
- University Hospital, Basel, Switzerland
Cancer Cachexia
Nutrition Education and Quality of Life in Cancer Cachexia
With the project the investigators propose, the investigators aim to find answers to the following questions: Are some cachectic factors and cytokines associated with plasma level irisin in patients with advanced stage cancer…
- Trial name
- NCT05262192
- Testing
- nutrition education
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Ordu University
Cancer
Slimming Myokines, Cancers,Nutritional and Psychology Support
With the project investigators propose, investigators aim to find answers to the following questions: The fact that irisin and atropine are slimming the proteins that cause an increase in weight loss, and the excessive wasting…
- Trial name
- NCT05278078
- Testing
- psychological support, nutritional education, psychological support and nutritional education
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Ordu University
Obesity
Impacts of Resistance Training on Acute Secretion of Irisin in Obese Older and Young Adults
It is established that resistance training improves metabolic health; however, the mechanisms of this process are not fully understood.
- Trial name
- NCT03715088
- Testing
- Resistance Training Intervention
- Where
- Canada
- Volunteers
- 31 people
- Sponsor
- University of New Brunswick
Bone Fracture
Metformin Effect on Fracture Healing in Post-Menopausal Women
study the effect of metformin drug on fracture healing of patients with high risk of delayed fracture healing or non-union and correlating this to serum irisin myokine level.
- Trial name
- NCT03845153
- Testing
- Metformin Retard 850 mg
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Damanhour University
Parkinson Disease, Idiopathic
Strength-Endurance Circuit Training in Parkinson's Disease
The goal of this clinical trial is to determine whether adding strength training to aerobic training has a comparable or greater effect on the clinical status of Parkinson's disease patients than a standalone aerobic training.
- Trial name
- NCT06893055
- Testing
- Strength-Endurance Training, Endurance Training
- Where
- Czechia
- Volunteers
- 90 people
- Sponsor
- General University Hospital, Prague
Osteoporosis, Osteopenia
Serum Myostatin and Irisin Levels in Postmenopausal Women: Association With Bone Mineral Density and Muscle Strength
This study aims to evaluate the relationship between serum myostatin and irisin levels and bone mineral density and muscle strength in postmenopausal women.
- Trial name
- MYOIRISIN (NCT07519551)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Sarcopenia, Obesity
Relationship Between Glycemic Control and Irisin in Type 2 Diabetic Patients With Sarcopenic or Non-sarcopenic Obesity
The goal of this observational study is to compare glycemic control and irisin levels in subjects with diabetes mellitus type 2 with sarcopenic obesity vs non-sarcopenic obesity.
- Conditions
- Sarcopenia, Obesity, Diabetes Mellitus, Type 2
- Trial name
- NCT05908812
- Where
- Italy
- Volunteers
- 120 people
- Sponsor
- Azienda Ospedaliero-Universitaria Consorziale Policlinico di Bari
Obesity
Circulating IL-6, Clusterin and Irisin in Obese Subjects
evaluate the circulating levels of IL-6, clusterin and irisin in obese subjects of both sexes who had different classes of obesity and their sexual dimorphism also identify the association of IL-6, clusterin and irisin with…
- Trial name
- NCT04133896
- Testing
- IL-6, Clusterin, Irisin Level
- Where
- Egypt
- Volunteers
- 176 people
- Sponsor
- Rehab Werida
Knee Osteoarthritis
The Effects of Healthy Lifestyle Management Training and Personalized Physical Activity Counseling: A Randomized Controlled Trial
Knee osteoarthritis is a common condition that causes knee pain, stiffness, and difficulty in daily activities. Physical activity and exercise are recommended as part of the treatment; however, many individuals have difficulty…
- Trial name
- RCT (NCT07333690)
- Testing
- Physiotherapist-Supervised Intervention, Home based self managed, Control
- Volunteers
- 26 people
- Sponsor
- Muhammed ARCA
Muscle Hypotrophy
The Effect of Blood Flow Restriction (Bfr) Exercise on Acute Systemic Myokine Levels in Healthy Trained Men
The aim of the study is to measure and compare acute systemic irisin, myostatin and decorin levels after a single session of blood flow restricted resistance exercise and resistance exercise without blood flow restriction in…
- Trial name
- NCT05573321
- Testing
- BFR-RE, HL-RE
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Ege University
Diabetic Nephropathies
Irisin Hormone as a Novel Diagnostic Marker for Detection and Progression of Diabetic Nephrophathy Patients
Study the relation between irisin level and progression of diabetic nephropathy and its early detection.
- Trial name
- NCT07435480
- Testing
- HBa1c, glucose
- Volunteers
- 200 people
- Sponsor
- Sohag University
Periodontal Diseases, Gingivitis
Asprosin, Adropin, Irisin Levels in Periodontitis
The recently discovered association of the hormones 'asprosin, adropin and irisin' with obesity and metabolic status, as well as the fact that periodontal diseases are affected by obesity and nutrition bilaterally, have led us to…
- Conditions
- Periodontal Diseases, Gingivitis, Obesity
- Trial name
- NCT06250764
- Testing
- Clinical periodontal measuremenets, ELISA test from gingival crevicular fluid (GCF)
- Where
- Turkey (Türkiye)
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- AYSAN LEKTEMUR ALPAN