Clinical trials: Iron Absorption
Iron Deficiency
Mineral Absorption From Fortified Rice Produced With Different Fortification Techniques
The investigators studies will compare iron, respectively iron and zinc bioavailability from fortified rice produced from different fortification techniques using stable isotopic labels.
- Trial name
- NCT02572128
- Testing
- Fortified rice
- Where
- 2 sites in Switzerland
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
Iron Deficiency Anaemia
A Pilot Study to Assess the Influence of Dietary Organic Acids on Iron Absorption.
Iron deficiency is the most common micronutrient deficiency in the world today, affecting more than 60% of the global population (www.who.int/nut/ida.htm).
- Trial name
- NCT01991600
- Testing
- ferrous sulphate, ferric iron oxide-organic acid (Fe-OA)
- Where
- United Kingdom
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- Medical Research Council
Sleep, Inadequate, Energy Deficit
The Effects of Repeated Operational Stress and Limited Recovery on Resilience Capacity
This longitudinal study will examine the effects of repeated bouts of operational stress and limited recovery on integrated MPS, whole-body protein balance, iron absorption, and aerobic performance.
- Conditions
- Sleep, Inadequate, Energy Deficit, Iron Absorption, High Physical Activity
- Trial name
- REP DEF (NCT06784544)
- Testing
- Operational Stressors
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- United States Army Research Institute of Environmental Medicine
Thalassemia, Iron Overload
Inhibitory Effect of a Polyphenol Supplement on Dietary Iron Absorption in Adults with Thalassemia
Genetic disorders, such as thalassemia, can lead to iron overload and severe adverse health outcomes. In iron-loading thalassemia, iron overload is due to increased iron absorption.
- Trial name
- NCT05326503
- Testing
- Meal matrix with polyphenol supplement (PPS), No meal matrix with PPS
- Where
- Thailand
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
Iron Deficiency
Effect of Vitamin C on Iron Absorption
Iron deficiency is a common health problem worldwide. Ferrous fumarate (a form of iron) is often added to foods in an effort to prevent iron deficiency.
- Trial name
- NCT00570895
- Testing
- Vitamin C
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Baylor College of Medicine
Iron-deficiency, Absorption; Iron
Iron Absorption From Iron-enriched Aspergillus Oryzae
Ferrous sulfate is rapidly absorbed and the bolus of iron enters blood rather quickly possibly leading to higher concentrations of non-transferrin bound iron which induces oxidative stress.
- Conditions
- Iron-deficiency, Absorption; Iron, Anemia, Iron Deficiency, Bioavailability
- Trial name
- BIEFS (NCT03156712)
- Testing
- Ferrous sulfate
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Iowa State University
Iron-deficiency, Iron Deficiency Anemia
Effects of Enhancers and Inhibitors on Absorption From Iron Supplements
Iron deficiency (ID) is a major public health problem worldwide and oral iron supplementation can be an effective strategy to treat and prevent ID.
- Trial name
- NCT05414474
- Testing
- Reference, Ascorbic acid (AA) 500 mg, Ascorbic acid (AA) 80 mg
- Where
- Switzerland
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
Iron-deficiency
Iron Absorption From Iron Fortified Extruded Rice Co-fortified With Various Solubilizing Agents
Food fortification is regarded as a safe and cost-effective approach to counteract and prevent iron deficiency. Rice is a staple food for millions of people living in regions where iron-deficiency anaemia is a significant public…
- Trial name
- NCT03703739
- Testing
- Reference meal 1, Reference 2, Test meal A
- Where
- Switzerland
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
Iron-deficiency
Effect of Polyphenols on Iron Absorption From Finger Millet
In India, one of the fast growing countries, 53% of all women have anaemia as per the National Family Health Survey. A recently published study on the burden of disease in India concluded that the burden of Iron deficiency…
- Trial name
- NCT04194567
- Testing
- Black Ragi, White Ragi
- Where
- 2 sites in Switzerland
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
Anemia, Iron Deficiency
Effect of Timing of Micronutrient Powder Consumption on Iron Absorption in Infants
Infants and young children in sub-Saharan Africa have high rates of iron deficiency anemia (IDA), which adversely affects their growth and cognitive development.
- Trial name
- NCT02989311
- Testing
- Fortified maize porridge (MNP and Iron), Fortified Maize porridge (MNP + Iron + GOS)
- Where
- Kenya
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
Pregnancy
Encapsulated Calcium Absorption in Pregnancy
This study will enroll at least 60 pregnant women in a randomized cross-over study in Dhaka, Bangladesh. Each participant will be randomized to one of 3 calcium doses: 500 mg, 1000 mg, 1500 mg elemental Ca per day.
- Trial name
- ENCAP (NCT01678079)
- Testing
- Encapsulated Calcium, Non-capsulated Calcium
- Where
- 4 sites in United States, Bangladesh and 1 more
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- The Hospital for Sick Children
Iron Deficiency, Anemia
Using Stable Iron Isotopic Techniques and Serum Hepcidin Profiles to Optimize Iron Supplementation
Oral iron supplementation (OIS) is a widely-used strategy to treat iron deficiency anemia. However, absorption of OIS is often low and response is variable.
- Conditions
- Iron Deficiency, Anemia, Iron Deficiency Anemia
- Trial name
- NCT01785407
- Testing
- Iron Supplement (Ferrous Sulfate Dried)
- Where
- Switzerland
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
Iron Absorption
Genetic Variants and Iron Absorption
The two specific aims of this study are: 1) to assess the impact of a genetic variant on iron status; 2) to assess the impact of a genetic variant on non-heme absorption among Asian women.
- Trial name
- NCT02197624
- Where
- United States
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Cornell University
Healthy
Study of the Iron Absorption From Capsules Containing Lactobacilli and Iron
The purpose of this study is to study the effect of a probiotic product on iron absorption in healthy females of child-bearing age.
- Trial name
- NCT02131870
- Where
- Sweden
- Volunteers
- healthy volunteers welcome
- Sponsor
- Probi AB
Adiposity, Iron-deficiency
Central and Peripheral Adiposity and Iron Absorption
Adiposity is a state of sub-clinical inflammation, thus hepcidin is increased in adiposity, often leading to iron deficiency in this population group.
- Trial name
- NCT03642223
- Testing
- Stable iron isotopes
- Where
- Lebanon
- Volunteers
- 121 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
Anemia, Iron Deficiency (Without Anemia)
The Immediate and Long-term Effects of a Novel Marine-based Iron Supplement in Adult Females
The goal of this study is to identify how well a fish-based iron supplement is absorbed and to learn how many, if any, digestive related side effects are caused by ingesting the supplement.
- Conditions
- Anemia, Iron Deficiency (Without Anemia), Iron Absorption
- Trial name
- NCT07199244
- Testing
- marine-based heme iron
- Where
- United States
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Nutraceuticals Research Institute
Iron Absorption
Iron Absorption in Vegetarian Children
Few areas are more controversial in pediatric nutrition than the role of a vegetarian diet for children. Advocates make strong health claims whereas others have expressed safety concerns, especially regarding iron nutrition.
- Trial name
- NCT01489007
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Baylor College of Medicine
Iron Metabolism Disorders
The Effect of Genetic Variation in TMPRSS6 Gene (SNP rs855791) on Oral Iron Absorption: an Iron Stable Isotope Study
Iron deficiency is considered the most common nutritional deficiency worldwide and affects children and women in both non-industrialized as well as industrialized countries.
- Trial name
- NCT03317873
- Testing
- Testmeal A, Testmeal B
- Where
- Taiwan
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
Resistance Exercise
Exercise and Galactooligosaccharide Supplementation on Inflammation and Iron Absorption (FexerGOS)
Iron depletion is common in female athletes depending on the sports discipline. Endurance and resistance exercise can induce inflammation thereby reducing dietary iron absorption.
- Trial name
- FexerGOS (NCT06038656)
- Testing
- Galactooligosaccharides (GOS)
- Where
- South Africa
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- North-West University, South Africa
Iron Deficiency
Effect of Coca-Cola on Iron Absorption
The aim of this project is to measure the effect of Coca-Cola and Diet Coke, relative to mineral water, on non-haem iron absorption.
- Trial name
- NCT00474500
- Testing
- Coca, Cola, Diet Coke
- Where
- United Kingdom
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Quadram Institute Bioscience