Clinical trials: Irritable Colon
Irritable Bowel Syndrome
Chronic Gastrointestinal Sequelae of an Acute Outbreak of Bacterial Gastroenteritis in Walkerton Ontario
Acute Bacterial dysentery leads to chronic symptoms of disturbed bowel habit in a minority of individuals. This condition known as post infectious irritable bowel syndrome (PI-IBS) remains poorly understood.
- Trial name
- NCT00235326
- Where
- Canada
- Volunteers
- 4,561 people, healthy volunteers welcome
- Sponsor
- McMaster University
Gastrointestinal Disorder, Functional
PHAGE Study: Bacteriophages as Novel Prebiotics
The PHAGE study is designed to determine if a commercial prebiotic product can change the composition of bacteria in the gut for improved intestinal health.
- Trial name
- NCT03269617
- Testing
- Bacteriophage mixture
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Colorado State University
Functional Bowel Disorder, Irritable Bowel Syndrome
The 5Ad Diet for Functional Bowel Disorders
The goal of this randomised controlled trial (RCT) is to compare the efficacy of the newly developed 5Ad diet against the widely researched low fermentable oligo-, di-, monosaccharide and polyols (FODMAP) diet in reducing…
- Conditions
- Functional Bowel Disorder, Irritable Bowel Syndrome, Food Intolerance, Food Intolerance Syndromes
- Trial name
- NCT06338189
- Testing
- The 5Ad Diet, The Low FODMAP Diet
- Where
- United Kingdom
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- University of Suffolk
IBS - Irritable Bowel Syndrome
The Prevalence of Irritable Bowel Syndrome Using Rome IV Criteria in Medical Student and The Related Factors
A cross-sectional study of 350 medical student Universitas Indonesia from first grade until fifth grade was done during November-December 2016. This study used stratified randomized sampling.
- Trial name
- IBS (NCT03178877)
- Testing
- No intervention
- Where
- Indonesia
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Functional Constipation, Irritable Bowel Syndrome Characterized by Constipation
Mode of Action of Moviprep
The University of Nottingham have been developing new, non-invasive magnetic resonance imaging (MRI) techniques to image the bowel.
- Trial name
- NCT01622972
- Testing
- Polyethyleneglycol
- Where
- United Kingdom
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Irritable Bowel Syndrome
Fructo-oligosaccharides and Irritable Bowel Syndrome
Fructo-oligosaccharides are known as prebiotic ingredients to modulate the composition of the intestinal microbiota and particularly to stimulate the growth of Bifidobacteria.
- Trial name
- NCT00806104
- Testing
- Fructo-oligosaccharides, Maltodextrins
- Where
- 2 sites in France, Spain
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Beghin-Meiji
Irritable Bowel Syndrome
Effect of MethylceIlulose or Psyllium on Fermentation of Inulin Assessed Using a Gas Sensing Capsule
The investigators plan to measure the local (in vivo) production of hydrogen when methylcellulose is ingested, to see if the investigators can show a shift of the site of fermentation to the distal colon.
- Trial name
- REALISTIC (NCT06551948)
- Testing
- psyllium, methylcellulose, maltodextrin
- Where
- United Kingdom
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Irritable Bowel Syndrome
Brain-derived Neurotrophic Factor Participates in Visceral Hyperalgesia in Irritable Bowel Syndrome (IBS) Patients
Brain-derived neurotrophic factor (BDNF), originally known to be a member of the nerve growth factor family, has aroused attention as a modulator in visceral hyperalgesia recently.
- Trial name
- NCT00925223
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Shandong University
IBS - Irritable Bowel Syndrome
Irritable Bowel Syndrome and Control Volunteers: Diet Challenge
The purpose of this study is to study the relationship between the bile acids, short chain fatty acids and bacteria within the intestines.
- Trial name
- NCT03983434
- Testing
- Inulin
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Indiana University
Irritable Bowel Syndrome
the Relationship Between Helicobacter Pylori Infection and Irritable Bowel Syndrome
Evaluating any possible relationship between irritable bowel syndrome occurrence and Helicobacter pylori infection
- Trial name
- NCT04847401
- Testing
- H. pylori stool antigen
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Sohag University
Irritable Bowel Syndrome, Colitis, Ulcerative
Advanced Metagenomic Analysis of Human Colonic Microbiota in Patients With Chronic GI Disorders
This clinical trial hypothesize that Gut Microbiota (bacteria, viruses, fungi)play a major role in the occurrence and progression of many chronic gastrointestinal diseases like Irritable Bowel Syndrome, Inflammatory Bowel…
- Conditions
- Irritable Bowel Syndrome, Colitis, Ulcerative, Crohn Disease, Colonic Neoplasms
- Trial name
- NCT01099111
- Where
- Saudi Arabia
- Volunteers
- 225 people, healthy volunteers welcome
- Sponsor
- King Fahad Medical City
Irritable Bowel Syndrome
Fecal Amino Acids，Gut Taste Receptors and Irritable Bowel Syndromes
Clinical data, fresh feces and intestinal mucosal tissues of patients with diarrheal IBS were collected. High performance liquid chromatography, immunohistochemistry and immunofluorescence were used to study the amino acid levels…
- Trial name
- NCT06489444
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital of Xi'an Jiaotong University
Irritable Bowel Syndrome With Diarrhea
To Study the Efficacy and Safety of L. Plantarum UALp-05TM in Diarrhea- Predominant-irritable Bowel Syndrome
Several probiotic strains have shown beneficial outcomes in IBS patients, particularly among the Lactobacillus and Bifidobacterium genera, Lactobacillus plantarum (recently reclassified as Lactiplantibacillus plantarum) is a…
- Trial name
- NCT04950296
- Testing
- Group I: L. plantarum UALp-05TM,, Group II: L. plantarum UALp-05TM,, Microcrystalline cellulose
- Where
- 12 sites in India
- Volunteers
- 314 people, healthy volunteers welcome
- Sponsor
- Vedic Lifesciences Pvt. Ltd.
Healthy, IBS - Irritable Bowel Syndrome
Microbiome Sampling in GI Disease With a Focus on Small Intestinal Microbial Assessment
GI disorders are influenced by the gut microbiome. To date, sampling of the small intestine in GI disorders has been limited. The investigators plan to sample the small intestinal contents during endoscopy for research purposes.
- Conditions
- Healthy, IBS - Irritable Bowel Syndrome, Inflammatory Bowel Diseases
- Trial name
- NCT06066866
- Testing
- endoscopic sampling of luminal fluid
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Stanford University
Proof of Concept, Irritable Bowel Syndrome
Validation of the Small Intestine Microbiome Aspiration (SIMBA) Capsule
Prospective, open label trial to establish the ability of the SIMBA Capsule to accurately obtain a sample from the small bowel of participants with IBS (10 constipation-predominant (IBS-C) and 10 diarrhea-predominant (IBS-D)) and…
- Trial name
- NCT04094558
- Testing
- Ingestible capsule, Sedated EGD, Lactulose Breath Test
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Irritable Bowel Syndrome
Phase I Clinical Trial of DA-6886 in Healthy Male Subjects
DA-6886_IBS_I is a phase I, dose block-randomized, double-blind, placebo-controlled, single/multiple dosing, dose escalation clinical trial with open-labelled food effect study of single dose to investigate the safety…
- Trial name
- NCT01633723
- Testing
- DA-6886
- Where
- South Korea
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Dong-A ST Co., Ltd.
Irritable Bowel Syndrome, Inflammatory Bowel Diseases
The Ecological Role of Yeasts in the Human Gut
Irritable bowel syndrome (IBS) and inflammatory bowel disease (IBD) (categorised into Crohn's disease (CD) and ulcerative colitis (UC)) are chronic gut disorders with debilitating symptoms that profoundly impact quality of life…
- Conditions
- Irritable Bowel Syndrome, Inflammatory Bowel Diseases, Gastrointestinal Disease
- Trial name
- YIG (NCT04138225)
- Where
- United Kingdom
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Grace Ward
Functional Gastrointestinal Disorders, Irritable Bowel Syndrome
Fructose Breath-testing in Irritable Bowel Syndrome (IBS)
Background: Breath testing for food intolerances is becoming routine in patients with functional gastrointestinal disorders (FGID).
- Trial name
- NCT02614313
- Testing
- Open breath test with fructose, Blinded breath test with fructose
- Where
- Switzerland
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Brain-Gut Research Group
Post-infectious Irritable Bowel Syndrome, Irritable Bowel Syndrome
Characterizing Protein Biomarkers of Post-infection Irritable Bowel Syndrome
The investigators will characterize and compare protein signatures between groups with and without post-infection irritable bowel syndrome (PI-IBS).
- Trial name
- NCT06032117
- Where
- United States
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- University of Nevada, Reno
Inulin, IBS (Irritable Bowel Syndrome)
The Effect of Inulin Supplementation in Individuals With IBS-C
Background: This study aimed to evaluate the effects of inulin supplementation on nutritional intake, anthropometric parameters, and bowel symptoms in individuals diagnosed with IBS-C.
- Conditions
- Inulin, IBS (Irritable Bowel Syndrome), Nutritional Status, Anthropometric Measurement
- Trial name
- NCT06945302
- Testing
- Intervention Group
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Mardin Artuklu University