Clinical trials: Irritation
Emotional Regulation, Problem Behavior
Examining the Impacts on In-School Behaviors of In-Home Videogame Play
The proposed study aims to investigate the effects of children's in-home engagement with a biofeedback video game-based intervention on children's in-school behaviors.
- Conditions
- Emotional Regulation, Problem Behavior, Irritable Mood
- Trial name
- NCT05260398
- Testing
- Mightier Online Gameplay
- Where
- United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Neuromotion Labs
Irritable Bowel Syndrome
Fecal Microbiota Transplantation to Relieve Symptoms of Irritable Bowel Syndrome With Constipation
Irritable bowel syndrome (IBS) is a complex multifactorial functional disorder, whose pathophysiology is largely associated to an impairment of the intestinal microbiota composition, namely dysbiosis.
- Trial name
- TRAMIR-S (NCT05803993)
- Testing
- Fecal microbiota transplantation (FMT) Single FMT infusion
- Where
- Italy
- Volunteers
- 35 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Irritable Bowel Syndrome
Efficacy, Safety, and Tolerability of JNJ-27018966 (Eluxadoline) in the Treatment of Irritable Bowel Syndrome With Diarrhea
The purpose of this study is to determine the efficacy, safety, and tolerability of different doses of JNJ-27018966 (eluxadoline) compared with placebo in the treatment of patients with irritable bowel syndrome with diarrhea…
- Trial name
- NCT01130272
- Testing
- Eluxadoline
- Where
- 288 sites in United States
- Volunteers
- 807 people
- Sponsor
- Furiex Pharmaceuticals, Inc
Irritable Bowel Syndrome
Small and Large Bowel Transit Tests Using MRI (Study 1)
Irritable bowel syndrome, (IBS) is a common functional disorder of the gut that can be quite disabling to patients. The most common symptoms of IBS are abdominal pain or discomfort along with erratic changes in bowel habit of…
- Trial name
- NCT01534507
- Where
- United Kingdom
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Non-constipation Irritable Bowel Syndrome
Study to Assess the Efficacy and Safety of SKI3246 in Subjects With Non-Constipation Irritable Bowel Syndrome
The purpose of this study is to determine the efficacy and safety of different doses of SKI3246 compared with placebo in the treatment of patients with irritable bowel syndrome with non-constipation.
- Trial name
- NCT02079675
- Testing
- SKI3246 Low Dose, SKI3246 High Dose
- Where
- South Korea
- Volunteers
- 279 people
- Sponsor
- SK Chemicals Co., Ltd.
Irritable Bowel Syndrome With Constipation, Chronic Constipation
An Open-label, Long-term Safety Study of Linaclotide in Patients With Chronic Constipation or Irritable Bowel Syndrome With Constipation
The objective of this study is to assess the long-term safety of linaclotide administered to patients with chronic constipation (CC) or irritable bowel syndrome with constipation (IBS-C).
- Trial name
- NCT00730171
- Testing
- Linaclotide
- Where
- 116 sites in United States
- Volunteers
- 1,743 people
- Sponsor
- Ironwood Pharmaceuticals, Inc.
Irritable Bowel Syndrome
Renal Involvement in Inflammatory Bowel Disease Patients
To evaluate renal involvement in inflammatory bowel disease patients .
- Trial name
- NCT04921709
- Testing
- Medical tests
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Assiut University
Irritable Bowel Syndrome
Gastrointestinal Symptoms in Healthy Subjects and Patients With Irritable Bowel Syndrome
The aim of this study performed in Irritable Bowel Syndrome (IBS) subjects and healthy patients is to demonstrate the ability of composite score of frequency of gastrointestinal symptoms to discriminate healthy subjects and IBS…
- Trial name
- NCT01457378
- Where
- 2 sites in France
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Danone Global Research & Innovation Center
Crohns Disease, Ulcerative Colitis
Integrative Gastroenterology - an Observational Trial
This study aims to test, if a two-week integrative therapy in an internal medicine ward will improve symptoms, disability and quality of life in patients with inflammatory bowel disease or irritable bowel syndrome.a It shall…
- Conditions
- Crohns Disease, Ulcerative Colitis, Irritable Bowel Syndrome
- Trial name
- InteGast (NCT02476643)
- Testing
- Integrative Therapy
- Where
- Germany
- Volunteers
- 200 people
- Sponsor
- Universität Duisburg-Essen
Inflammatory Bowel Disease
A Trial of Multi-convergent Therapy for Functional Symptoms and Stress in Patients With Inflammatory Bowel Disease
The purpose of this study is to determine whether multi-convergent therapy is helpful to patients with inflammatory bowel disease who have functional abdominal symptoms or high perceived levels of psychological stress.
- Trial name
- NCT01426568
- Testing
- Multi-Convergent Therapy
- Where
- United Kingdom
- Volunteers
- 66 people
- Sponsor
- Cardiff and Vale University Health Board
Healthy
Evaluation of Skin Irritation Potential With PF-06700841 Cream Formulation Using Negative Control in Adult Japanese Healthy Participants
This is a Phase 1, single center, randomized, vehicle and white petrolatum controlled, evaluator blinded study to assess the skin irritation potential with a range of concentrations of PF-06700841 cream including vehicle and…
- Trial name
- NCT03916250
- Testing
- PF-06700841 cream, White petrolatum
- Where
- Japan
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Pfizer
Healthy
Dermatological Evaluation of Topic Compatibility-Dermacyd Tina Gel Tangerina Mix
The purpose of this study is to demonstrate the absence of irritation potential (primary dermic irritability and cumulated dermic irritability) and allergy (sensibilization) of the product Dermacyd Tina Gel Tangerina Mix
- Trial name
- NCT00669058
- Testing
- Lactic acid (Dermacid)
- Where
- Brazil
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Sanofi
Acne Vulgaris, Allergic Rhinitis
MedlinePlus Health Prescriptions: Developing a Pragmatic Approach for Clinic Use
The specific aim of this proposed pilot study is to compare two standardized processes (paper and electronic) to deliver a customized MedlinePlus health information prescription.
- Conditions
- Acne Vulgaris, Allergic Rhinitis, Anxiety, Asthma
- Trial name
- NCT01050465
- Testing
- health information prescription
- Volunteers
- 907 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Depressive Disorder
Efficacy and Safety of Paroxetine Controlled Release for Major Depressive Disorder in Irritable Bowel Syndrome Patients
This is an open label, randomized, add-on, 8 weeks multicentre study to evaluate the efficacy and safety of paroxetine Controlled Release (CR) in patients with Major Depressive Disorder (MDD) comorbid Irritable Bowel Syndrome…
- Trial name
- NCT01916200
- Testing
- Paroxetine CR
- Sponsor
- GlaxoSmithKline
Irritable Bowel Syndrome
A Six-month Study to Compare Outcome Differences and Visceral Response ... Irritable Bowel Syndrome
The purpose of this study is to assess the effect of participation in one of the following interventions: (1) IBS Stress Management; (2) IBS Symptom Management; or (3) IBS Educational Training on improving IBS associated…
- Trial name
- NCT00368771
- Testing
- IBS Stress Management, IBS Symptom Management, IBS Educational Training
- Volunteers
- 163 people
- Sponsor
- University of California, Los Angeles
Irritability
Psychological Treatments for Youth With Severe Irritability.
Background: When children have severe irritability and temper outbursts, they can be so cranky or angry that it leads to problems at home, in school, and with friends.
- Trial name
- NCT02531893
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- National Institute of Mental Health (NIMH)
Irritable Bowel Syndrome, Inflammatory Bowel Diseases
Mucosal Innate Immune Activation in Chronic Intestinal Disorders
Crohn's disease and ulcerative colitis are types of chronic intestinal disorder called inflammatory bowel diseases (IBD) that can affect the small and large bowel causing symptoms of abdominal pain, diarrhea, blood in the stool…
- Trial name
- NCT03529318
- Testing
- Biopsies from endoscopy
- Where
- United States
- Sponsor
- University of Arkansas
Alpha-Gal Syndrome, Irritable Bowel Syndrome
GI Alpha-Gal Study
This is a double-blind, crossover food challenge study using pork with and without α-gal in patients with a clinical diagnosis of gastrointestinal (GI)- α-gal allergy, and to investigate the pathophysiology underlying their…
- Conditions
- Alpha-Gal Syndrome, Irritable Bowel Syndrome, Diarrhea, Abdominal Pain
- Trial name
- NCT06268717
- Testing
- Ground pork containing alpha-gal, Pork meat not containing alpha-gal
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of North Carolina, Chapel Hill
IBS
The Effects of Rifaximin Therapy in Irritable Bowel Syndrome
To evaluate the efficacy of Rifaximin therapy started prior to completion of advanced examination procedure (before colonoscopy) of patients pre-diagnosed with irritable bowel syndrome, and implement it into clinical practice.
- Trial name
- NCT02009618
- Testing
- Rifaximin
- Where
- Turkey (Türkiye)
- Volunteers
- 500 people
- Sponsor
- Bezmialem Vakif University
Irritable Bowel Syndrome (IBS), Irritable Bowel Syndrome With Diarrhea (IBS-D)
Curcumin, Vitamin D and Green Tea in IBS-D
Irritable Bowel Syndrome (IBS) is a highly prevalent condition of the gastrointestinal tract that has significant impact on sufferer's quality of life. The diarrhoea variant (IBS-D) makes up around one third of all IBS sufferers.
- Trial name
- NCT07052890
- Testing
- Curcumin, vitamin d and green tea extract
- Where
- 3 sites in United Kingdom
- Volunteers
- 78 people
- Sponsor
- Dr Anthony Hobson
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