Clinical trials: Ischemia Preconditioning
Abdominal Aortic Aneurysm, Peripheral Artery Disease
A Study of Remote Ischaemic Preconditioning in Patients With Atherosclerosis Undergoing Vascular Surgery
The purpose of this study is to evaluate the effect of preoperative remote ischaemic preconditioning (RIPC) on organ damage and the functional characteristics of arteries in patients undergoing vascular surgery.
- Conditions
- Abdominal Aortic Aneurysm, Peripheral Artery Disease, Carotid Artery Stenosis
- Trial name
- NCT02689414
- Testing
- Remote ischaemic preconditioning, Control to RIPC
- Where
- Estonia
- Volunteers
- 98 people
- Sponsor
- Tartu University Hospital
Vascular Function
Effects of SIT Combined with Remote Ischemic Preconditioning on Vascular Function in Young Women with Masked Obesity
Comparison of the effects of combined Sprint Interval Training (SIT) with Remote Ischemic Preconditioning (RIPC) and SIT on vascular function in young women with masked obesity.
- Trial name
- NCT06664281
- Testing
- SIT, SIT combined RIPC
- Where
- China
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Beijing Sport University
Unruptured Cerebral Aneurysm
Remote Ischemic PreConditioning (RIPC)
The purpose of this study is to learn about protecting the brain from low blood flow (ischemia) with limb preconditioning. From human studies the investigators know that the brain can be protected from dangerous low blood flow by…
- Trial name
- NCT03814850
- Testing
- Standard Manual Aneroid Sphygmomanometer
- Where
- 2 sites in United States
- Sponsor
- Sebastian Koch
Colon Cancer, Fragility
Prehabilitation of Frail Surgical Cancer Patients Using Remote Ischemic Preconditioning
This project will examine the efficacy of a simple, cost-effective, non-invasive intervention, called remote ischemic preconditioning (RIPC), to reduce frailty in pre-surgical, frail, elderly patients with colon cancer.
- Conditions
- Colon Cancer, Fragility, Prehabilitation, Surgery
- Trial name
- Prehab (NCT03853473)
- Testing
- Remote Ischemic Preconditioning
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Medical College of Wisconsin
Coronary Artery Disease, Valvular Heart Disease
Randomized Isoflurane and Sevoflurane Comparison in Cardiac Surgery
Anesthesia practice in the 21st century is increasingly outcomes-oriented and evidence-based, but there remain significant gaps in our knowledge, even for commonly-encountered clinical situations.
- Trial name
- RISCCS (NCT01477151)
- Testing
- Volatile anesthetic
- Where
- Canada
- Volunteers
- 464 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Peripheral Arterial Disease
Cardiac Remote Ischemic Preconditioning Before Elective Major Vascular Surgery
Vascular surgery is considered a high-risk operation with an anticipated risk of major cardiovascular complications in excess of 5%.
- Trial name
- CRIPES (NCT01403337)
- Testing
- Ischemic preconditioning, Control
- Where
- United States
- Volunteers
- 205 people
- Sponsor
- Center for Veterans Research and Education
Ischemic Preconditioning, Coronary Disease
Remote Ischaemic Conditioning and Coronary Endothelial Function (RIC-COR)
Intermittent arm cuff inflation reduces the extent of heart muscle injury at the time of cardiovascular injury. The intervention is known as remote ischaemic conditioning (RIC) however the mechanisms by which RIC acts are…
- Trial name
- RIC-COR (NCT02666235)
- Testing
- Remote ischaemic conditioning, Arm cuff placement, no inflation;
- Where
- United Kingdom
- Volunteers
- 60 people
- Sponsor
- NHS National Waiting Times Centre Board
Stroke
Protective Effects of Remote Limb Ischemic Preconditioning on Acute Cerebral Infarction
Stroke is one of the three leading causes of human death, and a major cause of adult disability. Our pre-clinical studies confirmed that ischemic preconditioning can prevent cerebral infarction.
- Trial name
- NCT01672515
- Testing
- RIPC group, Control group
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Capital Medical University
Liver Transplanatation
Remote Ischemic Preconditioning in Liver Transplantation
Remote (upper arm) ischemic preconditioning in the donor of living donor liver transplanta to ameliorate the effect of reperfusion injury in recipients.
- Trial name
- RIRI (NCT02534025)
- Testing
- Ischemia preconditioining
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Mansoura University
Effectivity of RIPC in Outcomes of TAVI Procedure
Cardioprotective Effect of RIPC in Patients Undergoing TAVI
We aim to investigate whether RIPC (remote ischemic preconditioning) is effective in the TAVI setting to reduce post-procedural myocardial damage and improve patient outcome.
- Trial name
- CARE-TAVI (NCT02283398)
- Testing
- without RIPC, RIPC
- Where
- 3 sites in Germany
- Sponsor
- Institut für Pharmakologie und Präventive Medizin
Intact Scaphoid Bone, Intact Metacarpal Bone
Bone Microcirculation After Remote Ischemic Preconditioning
In trauma surgery and hand surgery treatment strategies of none healing bone fractures aim at replacing pseudarthrosis by well vascularized bone and improving microcirculation.
- Conditions
- Intact Scaphoid Bone, Intact Metacarpal Bone, Fractured Scaphoid Bone, Fractured Metacarpal Bone
- Trial name
- NCT02554500
- Testing
- Remote Ischemic Preconditioning (by Blood Pressure Cuff)
- Where
- Germany
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University Hospital Schleswig-Holstein
Myocardial Injury, Cardiac Surgery
Effect of Cyclosporine and Remote Ischemic Preconditioning in Reperfusion Ischemia Injury on Tetralogy Fallot Patients With Correction Surgery
The study aimed to evaluate the combined effects of cyclosporine and remote ischemic preconditioning on MDA, calcium cytosol concentration, and mitochondrial edema in tetralogy Fallot patients undergoing corrective surgery.
- Trial name
- NCT05691764
- Testing
- Cyclosporin, remote ischemic preconditioning
- Where
- Indonesia
- Volunteers
- 40 people
- Sponsor
- Universitas Indonesia
Acute Myocardial Infarction
Effects of Long-term Remote Ischemic Preconditioning on Clinical Outcome in Patients With Acute Myocardial Infarction
At present, there are 290 million cardiovascular patients in China, including 11 million patients with coronary heart disease. Remote ischemic preconditioning(RIPC) may play an effective endogenous cardiac protection.This study…
- Trial name
- L-RICP-AMI (NCT07181356)
- Testing
- RIPerC, RIPC
- Where
- China
- Volunteers
- 2,146 people
- Sponsor
- Henan Institute of Cardiovascular Epidemiology
Renal Disease
Remote Ischemic Preconditioning Living Donor Renal Transplant Protocol
In this study, patients undergoing live donor kidney transplantation will be allocated to the control group or remote ischemic preconditioning group (RIPC).
- Trial name
- NCT03084666
- Testing
- Zimmer ATS tourniquet system
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Ischemic Preconditioning, Aerobic Capacity
Research on the Enhancement of Aerobic Metabolic Energy Supply Capacity by Ischemic Preconditioning.
The purpose of this clinical trial is to investigate whether IPC can improve aerobic capacity during exercise. The primary question it aims to answer is: Does IPC enhance the aerobic capacity of athletes? The researchers will…
- Trial name
- NCT07170774
- Testing
- Ischemic Preconditioning
- Where
- China
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Ziyue Ou
Liver Metastases
Hepatoprotective Effect of Remote vs Local Preconditioning of Liver
The aim of this study is to evaluate hepatoprotective effect from ischemia-reperfusion injury of remote ischemic preconditioning of the liver against local ischemic preconditioning of the liver during human liver resections.
- Trial name
- NCT03130920
- Testing
- Preconditioning
- Where
- Croatia
- Volunteers
- 60 people
- Sponsor
- University Hospital Dubrava
Myocardial Injury
Effects of Remote Ischemic PreConditioning in Off-pump Versus On-pump Coronary Artery Bypass Grafting(RIPCON)
Purpose Remote ischemic preconditioning (RIPC) with transient upper limb ischemia reduces myocardial injury in patients undergoing On-pump coronary artery bypass (CABG) surgery with cross-clamp fibrillation or blood cardioplegia…
- Trial name
- RIPCON (NCT01608984)
- Testing
- Remote ischemic preconditioning (RIPC), Coronary artery bypass grafting (CABG) without remote ischemic preconditioning protocol, Off-pump Coronary artery bypass surgery without remote ischemic preconditioning
- Where
- Germany
- Volunteers
- 100 people
- Sponsor
- Heinrich-Heine University, Duesseldorf
Moyamoya Disease, Remote Ischemic Preconditioning
Effects of Remote Ischemic Preconditioning With Postconditioning on Neurologic Outcome
In the present study, we evaluated whether RIPC with RIPostC reduce the major neurocomplication in patients undergoing STA-MCA anastomosis.
- Trial name
- NCT03072914
- Testing
- RIPC with RIPostC
- Where
- South Korea
- Volunteers
- 108 people
- Sponsor
- Seoul National University Hospital
Liver Neoplasms
Remote Ischemia Precondition (RIPC) for Hepatic Protection in Patients Undergoing Hepatectomy
Remote ischemia precondition could protect the liver from ischemia reperfusion injury in patients undergoing hepatectomy.
- Trial name
- NCT02168608
- Testing
- Remote ischemia precondition, None remote ischemia precondition
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Eastern Hepatobiliary Surgery Hospital
Atrial Fibrillation
Remote Ischemic Conditioning and Atrial Fibrillation After Coronary Artery Bypass Grafting (CABG)
Recent studies indicate that remote ischemic conditioning can protect the heart and other organs during cardiac surgery. The investigators aim to investigate whether such a stimulus can reduce the incidence of atrial fibrillation…
- Trial name
- RICO (NCT01107184)
- Testing
- Remote ischemic conditioning
- Where
- Netherlands
- Volunteers
- 191 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)