Clinical trials: Ischemic Cerebrovascular Accident
Transient Ischaemic Attack, Stroke
Psychoeducation for Transient Ischaemic Attack and Minor Stroke
Transient Ischaemic Attack (TIA), also called 'ministroke' is characterised by shortlasting symptoms that generally do not cause permanent damage.
- Trial name
- OPTIMISM (NCT02550392)
- Testing
- Psychoeducation
- Where
- United Kingdom
- Volunteers
- 64 people
- Sponsor
- University of Nottingham
Acute Cerebral Stroke Within 12 Hours for the First Time
Dl-3-n-butylphthalide and Cerebrolysin Treatment in Acute Ischemic Stroke
The investigators conducted a randomized, double-blind, trial enrolled 60 patients within 12 hours of acute ischemic stroke (AIS) in China.
- Trial name
- NCT02149875
- Testing
- Dl-3-n-butylphthalide, Cerebrolysin
- Where
- China
- Volunteers
- 84 people
- Sponsor
- Shanghai 6th People's Hospital
Myocardial Infarction, Cerebrovascular Accident
Analyzing Gene Regions That May Interact With the Effectiveness of High Blood Pressure Drugs
High blood pressure is one of the most common health problems in the United States. There are many drug treatment options for high blood pressure, but these medications are not always effective.
- Conditions
- Myocardial Infarction, Cerebrovascular Accident, Death, Sudden, Cardiac
- Trial name
- NCT00573092
- Where
- United States
- Sponsor
- University of Washington
Acute Ischemic Stroke
Predictive Factors of Outcome of Mechanical Thrombectomy After Acute Ischemic Stroke
Predictive factors of outcome of mechanical thrombectomy after acute ischemic stroke
- Trial name
- NCT03608644
- Volunteers
- 40 people
- Sponsor
- Assiut University
Stroke, Stroke, Ischemic
Coordinated, Collaborative, Comprehensive, Family-based, Integrated, Technology-enabled Stroke Care
Stroke is the 5th leading cause of death and the leading cause of adult disability in the United States (US). Stroke is a complex disease with multiple interacting risk factors (including genetic, high blood pressure and…
- Conditions
- Stroke, Stroke, Ischemic, Stroke, Acute, Stroke Sequelae
- Trial name
- C3FIT (NCT04000971)
- Testing
- Integrated Stroke Practice Unit, Comprehensive or Primary Stroke Center
- Where
- 21 sites in United States
- Volunteers
- 1,196 people
- Sponsor
- Vanderbilt University Medical Center
Carotid Stenosis, Carotid Artery Diseases
Modified Method of Eversion Carotid Endarterectomy in Patients With Extensive Atherosclerotic Disease of Carotid Bifurcation
A prospective comparative randomized single-centre non-inferiority trial. The purpose of this study is to compares of modified method of eversion carotid endarterectomy with standard eversion carotid endarterectomy for 3,6 and 12…
- Trial name
- NCT04255316
- Testing
- Modified method of eversion carotid endarterectomy, Standard method of eversion carotid endarterectomy
- Where
- Russia
- Volunteers
- 126 people
- Sponsor
- Pirogov Russian National Research Medical University
Stroke, Acute Ischemic Stroke
Trial of pRehospital Intervention With trAditional Chinese Medicine for Acute strokE
The main purpose of this trial is to observe whether Xingnaojing, intravenously administered within 24 hours of symptom onset on pre-hospital emergency ambulance, improves the Early neurological deterioration of acute stroke at 3…
- Conditions
- Stroke, Acute Ischemic Stroke, Acute Intracranial Hemorrhage
- Trial name
- TRACE (NCT04275349)
- Testing
- Xingnaojing injection within 24 hours of symptom onset
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Dongzhimen Hospital, Beijing
Acute Ischemic Stroke, Contrast-induced Nephropathy
Serum Electrolytes and Contrast-Induced Nephropathy in Acute Ischemic Stroke Patients Undergoing Endovascular Treatment
This study aims to evaluate the relationship between serum electrolyte levels and the development of contrast-induced acute kidney injury (CI-AKI) in patients with acute ischemic stroke undergoing endovascular therapy (EVT).
- Conditions
- Acute Ischemic Stroke, Contrast-induced Nephropathy, Acute Kidney Injury
- Trial name
- NCT07546448
- Testing
- No intervention (observational cohort study)
- Where
- Turkey (Türkiye)
- Volunteers
- 250 people
- Sponsor
- Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital
Coronary Artery Disease
Assessment of Coronary Artery Disease in Stroke Patients
This study is to evaluate the prevalence, plaque characteristics (plaque types, stenosis degree, remodeling) and predictors of coronary atherosclerosis in stroke patients with coronary CT angiography.
- Trial name
- ACADIS (NCT01850693)
- Where
- South Korea
- Volunteers
- 1,657 people
- Sponsor
- Seoul National University Hospital
Contraception, Female Contraception
Relative Risks for Non-fatal Venous Thromboembolism, Ischemic Stroke and Myocardial Infarction in Users of ORTHO EVRA(Norelgestromin and Ethinyl Estradiol Contraceptive Patch) Compared to Levonorgestrel-containing Oral Contraceptives.
This study uses the PharMetrics and MarketScan US health care insurance claims database to estimate relative risks for non-fatal venous thromboembolism (including cerebral venous sinus thrombosis), ischemic stroke, and acute…
- Conditions
- Contraception, Female Contraception, Fertility Control
- Trial name
- NCT00511784
- Volunteers
- 440 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Ischemic Stroke
Impact of Remote Ischemic Postconditioning on Autonomic Function in Stroke Patients
The purpose of this study is to determine whether remote ischemic postconditioning (RIPostC) initiates autonomic nervous system response and affects the prognosis in patients with acute ischemic stroke.
- Trial name
- IRAS (NCT02777099)
- Testing
- remote ischemic postconditioning
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Guangzhou University of Traditional Chinese Medicine
Stroke, Stroke, Ischemic
Behavioral Activation for Post-Stroke Sedentary Behavior Using Telehealth
Adults with stroke-related disability spend more time sedentary than adults without stroke-related disability, which places them at risk for poor cardiovascular health outcomes.
- Conditions
- Stroke, Stroke, Ischemic, Stroke Hemorrhagic
- Trial name
- teleABLE (NCT05029284)
- Testing
- teleABLE
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- University of Minnesota
Stroke Rehabilitation
Digital Interactive Technologies in Rehabilitation of Post-sroke Patients With Impaired Fine Function of the Hand
The aim of the study is to investigate the efficacy and safety of digital interactive technology with artificial intelligence and biofeedback Smart glove "SensoRehab" for restoration of in-hand manipulation in patients with…
- Trial name
- NCT05214521
- Testing
- digital interactive technology Smart glove "SensoRehab"
- Where
- Russia
- Volunteers
- 30 people
- Sponsor
- Moscow Scientific and Practical Center of Medical Rehabilitation, Restorative and Sports Medicine
Ischemic Stroke, Hemoadsorption
Hemoadsorption for Severe Ischemic Stroke
This is a multicenter, randomized-controlled, open-label, blinded endpoint clinical trial that aims to evaluate the efficacy and safety of hemoadsorption for severe ischemic stroke
- Trial name
- NCT07127484
- Testing
- Hemoadsorption
- Where
- China
- Volunteers
- 116 people
- Sponsor
- First Affiliated Hospital of Wannan Medical College
Acute Ischemic Stroke
Single Ascending Dose Safety and Tolerability of NTS-104 Healthy Adults
NTS-104 TRIS will be administered as a single intravenous dose to healthy subjects at doses of 0.8, 4, 8 and 16 mg/kg in 4 Cohorts.
- Trial name
- NCT05547438
- Testing
- NTS-104 TRIS
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- NeuroTrauma Sciences, LLC
Acute Ischemic Stroke, Thrombocytopenia
Antiplatelet Therapy for AIS Patients With Thrombocytopenia
The goal of this clinical trial is to test the safety and effectiveness of antiplatelet therapy in acute ischemic stroke (AIS) patients with thrombocytopenia.
- Trial name
- PERSIST (NCT06053021)
- Testing
- aspirin, clopidogrel, cilostazol, and dipyridamole
- Where
- China
- Volunteers
- 1,200 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Ischemic Stroke, Hemorrhagic Stroke
Correlation Between Intestinal Microecology Imbalance and Stroke in Young Adults
The relationship between the intestinal microecology and stroke has become a research hotspot in neurology field today. Maintaining the balance of the intestinal microbiota are expected to bring new breakthroughs for prevention…
- Trial name
- NCT05113043
- Where
- 2 sites in China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Shanghai 6th People's Hospital
Acute Ischemic Stroke
Optimizing Reperfusion to Improve Outcomes and Neurologic Function
The goal of this study is to evaluate the safety and efficacy of JX10 versus placebo in participants with Acute Ischemic Stroke (AIS) who present for care within 4.5 to 24 hours. The main question the study aims to answer are: 1.
- Trial name
- ORION (NCT06990867)
- Testing
- JX10
- Where
- 104 sites in United States, Belgium and 19 more
- Volunteers
- 740 people
- Sponsor
- Corxel Pharmaceuticals
Ischemic Stroke
Effect of Aspirin at the Acute Phase of Cerebral Ischemic Event.
Aspirin is the only anti-platelet medication used at the acute phase of ischemic stroke. The investigators would like to study laboratory effect of the first oral 300 mg dose of aspirin, given at hospital, after an ischemic…
- Trial name
- Aspirin (NCT01375400)
- Testing
- Aspirin, blood sample
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Central Hospital, Nancy, France
Hemorrhagic Transformation Stroke
Robot-Assisted Hematoma Evacuation With Intrahematoma Tenecteplase for Post-Reperfusion PH2 Hemorrhagic Transformation
The purpose of this phase I trial is to evaluate the safety and feasibility of robot-assisted stereotactic minimally invasive hematoma aspiration, followed when eligible by intrahematoma tenecteplase administration, in patients…
- Trial name
- REPORT (NCT07641998)
- Testing
- Robot-assisted stereotactic hematoma aspiration plus intrahematoma tenecteplase
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Beijing Tiantan Hospital
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