Clinical trials: Ischemic Postconditioning, active
Acute Ischemic Stroke
Rapid Local Ischemic Postconditioning on Stroke After Thrombectomy
The main goal of this study is to find out if a new, quick "brain rescue" procedure can help people recover better from a severe stroke caused by a large vessel occlusion.
- Trial name
- RAPIDIMPROVE (NCT07598799)
- Testing
- High-dose RL-IPostC, Low-dose RL-IPostC
- Where
- China
- Volunteers
- 448 people
- Sponsor
- Shanghai Jiao Tong University Affiliated Sixth People's Hospital
ST Segment Elevation Myocardial Infarction
Ischemic Postconditioning in STEMI Patients Treated With Primary PCI
In a prospective, randomized clinical trial the iPOST2 trial will determine whether ischemic postconditioning reduces reperfusion injury and this will translate into improved clinical outcome of heart failure and death for STEMI…
- Trial name
- iPOST2 (NCT03787745)
- Testing
- Ischemic postconditioning, Conventional
- Where
- Denmark
- Volunteers
- 1,800 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Ischemic Stroke
Oriental Research AlliaNce of Acute Ischemic Stroke Given Endovascular Treatment
To determine the safety and efficacy of in situ ischemic postconditioning immediately after successful reperfusion in AIS patients underwnet EVT.
- Trial name
- ORANGE (NCT05024292)
- Testing
- rapid local ischemic postconditioning (RL-IPostC)
- Where
- 2 sites in China
- Volunteers
- 160 people
- Sponsor
- Shanghai Jiao Tong University Affiliated Sixth People's Hospital
Adult Patients With Septic Shock Admitted in Intensive Care Unit
Remote Ischemic Postconditioning in Septic Shock
Septic shock is a leading cause of death worldwide despite intensive research efforts. Only a few interventions have been proven to be effective in improving patient-centered outcomes.
- Trial name
- RIPOST-sepsis (NCT07273942)
- Testing
- Remote ischemic conditioning, No intervention
- Where
- 23 sites in France
- Volunteers
- 720 people
- Sponsor
- Hospices Civils de Lyon
ST Elevation Myocardial Infarction
STEMI Treatment Optimization by Ischemic Postconditioning and IVUS Guidance
The purpose of is study is to investigate whether ischemic postconditioning (iPOST) and intravascular ultrasound-guided (IVUS) percutaneous coronary intervention (PCI) improve the clinical outcome of patients with ST-segment…
- Trial name
- DANAMI4 (NCT04775914)
- Testing
- PCI + Ischemic conditioning, Stent with ultrasound
- Where
- Denmark
- Volunteers
- 2,500 people
- Sponsor
- Thomas Engstrom
Out-Of-Hospital Cardiac Arrest
Neuroprotective Effect of Remote Ischemic Post-conditioning in Out-of-hospital Cardiac Arrest
Patients admitted to intensive care unit (ICU) following an out-of-hospital cardiac arrest (OHCA) have a high morbidity and mortality rate, primarily due to ischemia-reperfusion (I/R) syndrome leading to anoxic-ischemic brain…
- Trial name
- RIPOST-CA (NCT06473207)
- Testing
- Remote ischemic post conditioning sessions
- Where
- France
- Volunteers
- 48 people
- Sponsor
- Centre Hospitalier Intercommunal de Toulon La Seyne sur Mer
ST Elevation Myocardial Infarction
Remote Ischemic Conditioning With Local Ischemic Postconditioning in High-Risk ST-elevation Myocardial Infarction
The RIP-HIGH trial is a two-arm randomized controlled trial aiming to compare the impact of combined remote ischemic conditioning (RIP) and local ischemic postconditioning (PostC) vs.
- Trial name
- RIP-HIGH (NCT04844931)
- Testing
- RIC + PostC + Standard PCI, Standard PCI
- Where
- 11 sites in Austria, Germany
- Volunteers
- 250 people
- Sponsor
- Helios Health Institute GmbH