Clinical trials: Isolation
Multiple Sclerosis, Radiologically Isolated Syndrome
Epstein Barr Virus Infection in Patients With Radiologically Isolated Syndrome
The clinical course of RRMS patients is variable. Among RIS-Consortium international cohorts, one third of RIS patients progressed to MS at 5 years and 52.2% at 10 years.
- Conditions
- Multiple Sclerosis, Radiologically Isolated Syndrome, Epstein-Barr Virus
- Trial name
- EBV-RIS (NCT05815108)
- Testing
- NO INTERVENTION
- Where
- France
- Volunteers
- 156 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Melanoma, In-Transit Metastasis
Evaluating the Effect of Nivolumab for Patients With In-transit Metastases Treated With Isolated Limb Perfusion
To evaluate safety and the effect of isolated limb perfusion together with nivolumab as a way to increase efficacy and give further insights in early immunological mechanisms.
- Trial name
- NivoILP (NCT03685890)
- Testing
- Nivolumab, Isolated limb perfusion (ILP)
- Where
- 4 sites in Netherlands, Sweden
- Volunteers
- 74 people
- Sponsor
- Vastra Gotaland Region
Ovarian Cancer, Recurrent Ovarian Carcinoma
Secondary Cytoreductive Surgery in Platinum-resistant Recurrent Ovarian Cancers
This novel study was specifically designed for platinum resistant recurrent ovarian cancers and aimed to compare cases who received secondary cytoreductive surgery for isolated recurrence and chemotherapy versus chemotherapy…
- Trial name
- NCT04795596
- Testing
- secondary cytoreductive surgery, Chemotherapy
- Where
- Egypt
- Sponsor
- Menoufia University
Receding Chin
Esthetic Outcome of Isolated Advancement Genioplasty With and Without Submental Liposuction in Treatment of Skeletal Chin Deficiency
This study is to measure the eshetic outcome of of isolated advancement genioplasty with and without submental liposuction in treatment of skeletal chin deficiency in double chin patients
- Trial name
- NCT04283708
- Testing
- Submental liposuction
- Where
- Egypt
- Volunteers
- 22 people
- Sponsor
- Cairo University
Sarcoma, Myxofibrosarcoma
A Study of Pembrolizumab Plus Local Chemotherapy Using Isolated Limb Infusion (ILI) for Patients With Sarcoma in the Arm or Leg
The purpose of this study is to find out whether giving the study drug pembrolizumab in combination with the chemotherapy drugs melphalan and dactinomycin, delivered directly to the affected arm or leg using a technique called…
- Conditions
- Sarcoma, Myxofibrosarcoma, Undifferentiated Pleomorphic Sarcoma, Alveolar Soft Part Sarcoma
- Trial name
- NCT04332874
- Testing
- Isolated Limb Infusion, Pembrolizumab, infusion of melphalan and dactinomycin
- Where
- 7 sites in United States
- Volunteers
- 30 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Communication, Anxiety
AYA-PeerConnect: A Communication Coaching Intervention for Adolescent/Young Adult Cancer Survivors (AYACS)
This research is being done to test a communication coaching intervention pilot designed to improve communication quality between adolescent/young adult cancer survivors (AYACS) and their friends/peers.
- Conditions
- Communication, Anxiety, Depression, Social Isolation
- Trial name
- NCT07454460
- Testing
- Asynchronous coaching and artificial intelligence (AI) Yoodli coach sessions
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Milton S. Hershey Medical Center
Hip Fractures, Nerve Block
PENG vs. FIC Blocks in Hip Fractures in the ED
This study is a prospective, randomized clinical trial assessing the efficacy of physician-performed ultrasound-guided pericapsular nerve group (PENG) block vs fascia iliaca compartment (FIC) block for pain control in acute hip…
- Conditions
- Hip Fractures, Nerve Block, Analgesia
- Trial name
- NCT06336460
- Testing
- Pericapsular Nerve Group (PENG) Block, Fascia Iliaca Compartment (FIC) Block for Patients with Isolated Hip Fractures
- Volunteers
- 60 people
- Sponsor
- Orange Park Medical Center
Median Nerve Entrapement
Large Scale ICU Data Sharing for 1000 Critically Ill Patients With Severe Acute Respiratory Distress Syndrome Coronavirus (SARS.COV19) in Three Distinct Isolation Centers
Cohort study of patients with severe respiratory distress syndrome coronavirus2 in three different isolation hospitals recording data about outcome.
- Trial name
- NCT04779268
- Where
- Egypt
- Volunteers
- 1,000 people
- Sponsor
- Minia University
Social Isolation
Physical Activity During Social Isolation
The aim of the study is to evaluate the physical activity level and the factors affecting physical activity among young adults who are socially isolated due to coronavirus.
- Trial name
- NCT04339491
- Where
- Turkey (Türkiye)
- Volunteers
- 1,206 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Atrial Fibrillation
Giant Left Atrium Atrial fibrillatioN CathEter Ablation, Posterior Box Isolation vs. Dallas Lesion Set
Although the additional linear ablation after pulmonary vein isolation (PVI) is a class IIB indication for AF catheter ablation in patients with persistent AF, no clear benefit has been demonstrated in the recent randomized…
- Trial name
- NCT04632550
- Testing
- Circumferential pulmonary vein isolation(CPVI) group, Posterior box isolation(POBI) group, POBI+Anterior linear ablation(AL) group
- Where
- South Korea
- Volunteers
- 480 people
- Sponsor
- Yonsei University
Aging, Social Isolation
HARP-Project 1 Cognitive Training
Emerging evidence from social neuroscience suggests that prefrontal cortex (PFC), insular and anterior cingulate cortex (ACC) regulate social and emotional responses to acute threats to social connectedness among young adults.
- Trial name
- NCT03293823
- Testing
- VSOP training, MLA control
- Where
- 4 sites in United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Musculoskeletal Diseases
Isolation, Characterization and Evaluation of the Potential of TissuE-resideNt cElls From Waste Musculoskeletal and Associated Connective Tissues
The general purpose of this study is characterization of tissue-resident cells derived from different musculoskeletal and/or associated connective tissues (such as cartilage, synovial membrane, synovial fluid, bone, adipose…
- Trial name
- TENET(L4165) (NCT05471752)
- Where
- Italy
- Volunteers
- 742 people
- Sponsor
- I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio
Atrial Fibrillation
Pulmonary Vein (PV) -Isolation: Arrhythmogenic Vein(s) Versus All Veins
We conduct a randomized study comparing the safety and effectiveness of two interventional ablation techniques for treatment of paroxysmal atrial fibrillation: the segmental pulmonary vein ablation approach, (1) with empiric…
- Trial name
- PAVAV (NCT00605748)
- Testing
- Segmental PV-Isolation of the arrhythmogenic vein(s), Segmental PV-Isolation of all veins
- Where
- Germany
- Volunteers
- 212 people
- Sponsor
- Deutsches Herzzentrum Muenchen
Atrial Fibrillation, Recurrence
Impact of Short-course Colchicine Versus Placebo After Pulmonary Vein Isolation (IMPROVE-PVI Pilot)
Recurrence is a common problem after catheter ablation for atrial fibrillation, affecting at least one out of three patients. Inflammation due to the procedure may contribute to pulmonary vein reconnection and, thus, failure of…
- Trial name
- NCT04160117
- Testing
- Colchicine 0.6 mg
- Where
- Canada
- Volunteers
- 202 people
- Sponsor
- Population Health Research Institute
Pro and Anti Inflamatory Cytokines, Pain
CBD Supplementation in Brazilian Jiu-Jitsu Athletes
Brazilian Jiu-Jitsu (BJJ) is a high-intensity martial art that imposes significant physical and physiological demands on practitioners, including rigorous training and frequent competitions, which can result in chronic…
- Conditions
- Pro and Anti Inflamatory Cytokines, Pain, Sleep, Quality of Life
- Trial name
- CBD-BJJ-RCT (NCT07552974)
- Testing
- CBD Isolate 100mg BID
- Where
- Brazil
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Associação Pan-Americana Multidisciplinar de Endocanabinologia
Circulating Tumor Cells
Culture of Circulating Tumor Cells Isolated From Cancer Patients With Metastatic Disease
The purpose of this study is to investigate the feasibility of using novel decellularized tissue matrices to isolate and culture circulating tumor cells (CTCs) collected from patients with metastatic solid tumor malignancies.
- Trial name
- NCT02781025
- Testing
- Blood draw
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- UNC Lineberger Comprehensive Cancer Center
Onychomycosis, Resistant Infection
Mycosis Culture Collection From Dermatological Isolated
This pilot, prospective, observational drug study aims to evaluate the efficacy, tolerability and safety of topical and oral antifungals in the treatment of onychomycosis caused by yeasts, dermatophytic moulds and…
- Conditions
- Onychomycosis, Resistant Infection, Nail Diseases
- Trial name
- MYCDERM (NCT05482763)
- Testing
- Terbinafine Topical Gel, Itraconazole 200 mg, Terbinafine 250 mg
- Where
- Italy
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Rome Tor Vergata
Growth Hormone Deficiency
Consequence of Lifetime Isolated Growth Hormone Deficiency
Growth hormone (GH) deficiency (GHD) in adulthood has been associated with changes in body composition (e.g. increased abdominal obesity, and reduced muscle mass), in organ functions (e.g.
- Trial name
- NCT00149708
- Testing
- growth hormone administration for 6 months
- Where
- Brazil
- Volunteers
- 400 people
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Systolic Essential Hypertension
Non-pharmacological Treatment for Essential Isolated Systolic Hypertension in Elderly
The previous studies used the slow loaded breathing device for breathing training (Jones et al., 2010). It has been shown that slow loaded breathing training can reduce resting blood pressure and heart rate in essential…
- Trial name
- NCT02200926
- Testing
- Loaded breathing training, Unloaded breathing training
- Where
- Thailand
- Volunteers
- 30 people
- Sponsor
- Khon Kaen University
Cleft Palate
Validation of a Production Method of Stem Cell Isolated From the Nasal Cavity for an Innovative Cell Therapy of Cleft Palate
Cell therapy appears to be an alternative to treat bone defects. Scientific advances have shown in animal models and in humans that mesenchymal stem cells were good candidates to support cellular bone regeneration after…
- Trial name
- NCT02900014
- Testing
- sampling mesenchymal stem cells
- Where
- France
- Volunteers
- 2 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
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