Clinical trials: Isolation
MRSA Colonization
Incidence of Methicillin Resistant Staphylococcus Aureus (MRSA) Carriage Rates in Resident Physicians
One hundred new residents will be recruited prior to the start of residency and followed prospectively for a year. Monthly nasal swabs will be performed to identify colonization with methicillin resistant staphylococcus aureus…
- Trial name
- NCT00929435
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma
Methicillin Resistant Staphylococcus Aureus
Detection, Education, Research and Decolonization Without Isolation in Long-term Care Facilities
Our hypothesis for the DERAIL MRSA program is that one can safely remove the colonization risk from nearly all residents (patients) in a way that does not interfere with the desired life-style for persons in these facilities and…
- Trial name
- DERAIL_MRSA (NCT01302210)
- Testing
- Decolonization
- Where
- United States
- Volunteers
- 22,302 people
- Sponsor
- Endeavor Health
Atrial Fibrillation
Inflammatory Response as a Prognostic Factor of Recurrence of Atrial Fibrillation After Ablation
The aim of this study is to evaluate inflammatory response as a prognostic factor of atrial fibrillation recurrency after ablation.
- Trial name
- ACtIVE-AF (NCT02844959)
- Where
- Poland
- Volunteers
- 120 people
- Sponsor
- Medical University of Warsaw
Mastocytosis
Hydroxychloroquine in Isolated Cutaneous Mastocytosis Patients or Indolent Systemic Mastocytosis With Associated Skin Involvement Patients
The treatment of systemic mastocytosis has two main axes: Control of mast cell activation symptoms and The control of proliferation (accumulation) of mast cells.
- Trial name
- HCQMa (NCT05084872)
- Testing
- Hydroxychloroquine
- Where
- France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Toulouse
Pulmonary Neoplasm
Impact of Different Lung Isolation Devices on Pharyngolaryngeal Injuries After Pulmonary Resection
The goal of this clinical trial is to assess the impact of laryngeal mask combined with visual bronchial blocker on pharyngolaryngeal injury after pulmonary resection in patients with pulmonary nodules.
- Trial name
- PLIAP (NCT07117539)
- Testing
- visual bronchial blocker (VBB), double-lumen endotracheal tube (DLT)
- Where
- 3 sites in China
- Volunteers
- 270 people
- Sponsor
- Tingting Li
Atrial Fibrillation
AF Burden and Echo-guided Persistent AF Ablation Strategy Using Either PV Isolation Alone (CLOSE Protocol) or Optimized Compartmentalization of the Left Atrium (Pseudo-maze Technique)
Recent publications suggest that neither empirical nor individualized substrate modification strategies could improve single-procedure efficacy beyond pulmonary vein (PV) isolation for persistent atrial fibrillation (AF).
- Trial name
- CLOSEMAZE (NCT04773119)
- Testing
- PVI only, PVI with substrate ablation
- Where
- Belgium
- Volunteers
- 62 people
- Sponsor
- AZ Sint-Jan AV
Bronchiolitis
Cohort Isolation and Cross-infection in Bronchiolitis
The purpose of this study is to investigate the effect of cohort isolation of RS(respiratory syncytial virus)-positive bronchiolitis versus RS-negative bronchiolitis on prevention of co-infection and clinical disease severity.
- Trial name
- NCT01441466
- Testing
- Isolation
- Where
- Netherlands
- Volunteers
- 48 people
- Sponsor
- Princess Amalia Children's Clinic
Atrial Fibrillation; Paroxysmal Atrial Fibrillation; Persistent Atrial Fibrillation
Pulsed Field Ablation of Atrial Fibrillation: CENTAURI Versus FARAPULSE
The aim of this study is to compare the efficacy of two commercially available pulsed field ablation (PFA) systems for catheter ablation of atrial fibrillation.
- Trial name
- NCT07902739
- Testing
- CENTAURI PEF system, FARAPULSE system
- Where
- Czechia
- Volunteers
- 325 people
- Sponsor
- St. Anne's University Hospital Brno, Czech Republic
Hypertension
A Safety and Efficacy Trial of Aliskiren 150mg , 300 mg Compared to Ramipril 5mg, 10mg in the Elderly
Evaluate the systolic blood pressure lowering effect of aliskiren 150mg and 300mg compared to ramipril 5mg and 10mg in elderly patients with essential systolic hypertension.
- Trial name
- NCT00368277
- Testing
- Aliskiren, Ramipril, Hydrochlorothiazide
- Where
- United States
- Volunteers
- 901 people
- Sponsor
- Novartis Pharmaceuticals
Atrial Fibrillation (AF)
Structured Treatment and Resource Efficiency Assessment With Lean Six Sigma Integration for Pulmonary Vein Isolation
The STREAMLINE-PVI trial is a prospective, single-center, randomized, open-label clinical trial comparing pulsed field ablation (PFA) with cryoballoon ablation (Cryo) for pulmonary vein isolation (PVI) in patients with atrial…
- Trial name
- STREAMLINE PVI (NCT07910370)
- Testing
- Pulsed Field Ablation (PFA), Cryoballoon Ablation (Cryo)
- Where
- Germany
- Volunteers
- 94 people
- Sponsor
- St. Josefs-Hospital Wiesbaden GmbH
Urinary Tract Infections (UTIs), Catheter-Associated Urinary Tract Infections (CAUTIs)
Antibiofilm Activity of Chitosan Nanoparticles Against Uropathogenic Escherichia Coli
1. Isolation of uropathogenic Escherichia coli (UPEC) and determination of their Antimicrobial sensitivity Patterns. 2. Evaluation of biofilm-forming capacity of UPEC isolates. 3.
- Conditions
- Urinary Tract Infections (UTIs), Catheter-Associated Urinary Tract Infections (CAUTIs), Biofilm Formation by Uropathogenic Escherichia Coli (UPEC)
- Trial name
- NCT07482553
- Testing
- chitosan nanoparticles
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Assiut University
Multiple Sclerosis, Multiple Sclerosis, Relapsing-Remitting
Longitudinal Effect of Vitamin D3 Replacement on Cognitive Performance and MRI Markers in Multiple Sclerosis Patients
This is a longitudinal single blind randomized trial to test the effects of high compared to low dose vitamin D3 supplementation on cognitive performance at 6 and 12 months, and MRI measures of 12 months duration.
- Conditions
- Multiple Sclerosis, Multiple Sclerosis, Relapsing-Remitting, Clinically Isolated Syndrome, Clinically Isolated Syndrome, CNS Demyelinating
- Trial name
- NCT03610139
- Testing
- Vitamin D3
- Where
- Lebanon
- Volunteers
- 162 people
- Sponsor
- American University of Beirut Medical Center
Multiple Sclerosis, Clinically Isolated Syndrome
A Study Evaluating B Cell Levels In Infants Potentially Exposed To Ocrelizumab During Pregnancy
This study will evaluate the potential placental transfer of ocrelizumab in pregnant women with clinically isolated syndrome (CIS) or multiple sclerosis (MS) [in line with the locally approved indications] whose last dose of…
- Trial name
- MINORE (NCT04998812)
- Testing
- Ocrelizumab
- Where
- 11 sites in United States, France and 3 more
- Volunteers
- 70 people
- Sponsor
- Hoffmann-La Roche
Social Isolation, Loneliness
Engage Coaching for Latinos
This study asks: "what behavioral strategies are needed to help socially disconnected Hispanic/Latino caregivers with significant barriers to increasing connectedness?" This study uses a mixed methods approach to adapt a brief…
- Conditions
- Social Isolation, Loneliness, Caregiver Burnout
- Trial name
- NCT04875065
- Testing
- Engage coaching
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Rochester
Persistent Atrial Fibrillation
Cryoballoon Pulmonary Vein Isolation vs. Cryoballoon Pulmonary Vein Isolation With Additional Right Atrial Linear Ablation for Persistent Atrial Fibrillation (CRARAL Trial)
Cryoballoon ablation is proven to be effective in pulmonary vein isolation in patients with paroxysmal atrial fibrillation. However, it is not certain that cryoablation is effective and safe in patients with persistent atrial…
- Trial name
- NCT03682887
- Testing
- Cryoballoon PV isolation group, Cryoballoon PV isolation with Additional RA linear ablation group
- Where
- South Korea
- Volunteers
- 195 people
- Sponsor
- Yonsei University
Postoperative Complications
Effect of Different Anesthetic Techniques for Isolated Systolic Hypertensive Patients of Abdominal Surgery on Postoperative Hospital Stay and Morbidity
In General anesthesia, two main ways of pain control are used intra-operatively, one is opioids, the other is epidural. Many colleges prefer using epidural analgesia because it is potent and more effective , and also the benefits…
- Trial name
- NCT01884298
- Where
- China
- Sponsor
- Peking University First Hospital
Aging, Healthy, Risk Reduction
The REMINDER Program for Older Adults Supported by Residential and Daycare Facilities
Dementia and mild cognitive impairment (MCI) deeply impact individuals' well-being and are expected to increase due to population aging, with global cases projected to rise to 152.8 million by 2050.
- Conditions
- Aging, Healthy, Risk Reduction, Old Age; Dementia
- Trial name
- REMINDER (NCT06733181)
- Testing
- REMINDER intervention
- Where
- Portugal
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of Coimbra
Atrial Fibrillation, Atrial Arrhythmia
Studying Heart Ablation After Left Atrial Closure in High-Bleeding-Risk Atrial Fibrillation Patients
The purpose of this multicenter study is to collect information from routine clinical practices for patients with left atrial appendage occlusion (LAAO) devices presenting for pulmonary vein isolation (PVI) or left atrial…
- Trial name
- PROCEED-AF (NCT07580937)
- Testing
- Data collection
- Where
- 20 sites in United States, Belgium and 7 more
- Volunteers
- 198 people
- Sponsor
- University of Chicago
Lung Diseases
Impact of Patient Position on the Success in Placing Triple-cuffed Double Lumen Endotracheal Tube
Triple-cuffed double lumen endotracheal tube (TC-DLT, ANKOR tube. Insung corp., Korea) which was developed to isolate lung without endotracheal bronchoscope guidance has additional carinal cuff placed between bronchial tube cuff…
- Trial name
- NCT05462275
- Testing
- Intubation using 3-cuffed double lumen endotracheal tube
- Where
- South Korea
- Volunteers
- 167 people
- Sponsor
- Hansu Bae
Cleft Palate Children, Laser
Low Level Laser in Isolated Cleft Palate Repair Versus Surgical Correction Without LLL in Healing Process
Does the use of low level laser (LLL) after surgical correction of cleft palate improve healing and decrease incidence of oronasal fistula?
- Trial name
- NCT03688737
- Testing
- low level laser
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Cairo University
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