Clinical trials: Isolation
Atrial Fibrillation Paroxysmal
Cardioneuroablation for the Treatment of Vagally-mediated Atrial Fibrillation.
Pulmonary vein isolation (PVI) is a cornerstone for catheter ablation of atrial fibrillation (AF), however, exact mechanisms of PVI efficacy remain debatable.
- Trial name
- NCT05461859
- Testing
- Cardioneuroablation (CNA) of the right anterior ganglionated plexus (RAGP)
- Where
- Poland
- Volunteers
- 18 people
- Sponsor
- St. Joseph's Centre, Poland
Coronary Artery Bypass Graft (CABG), Postoperative Pain
Multimodal Fascial Plane Block for Postoperative Analgesia in Isolated CABG Surgery
Postoperative pain following coronary artery bypass grafting (CABG) via median sternotomy remains a significant clinical problem and is associated with increased opioid consumption and postoperative complications.
- Conditions
- Coronary Artery Bypass Graft (CABG), Postoperative Pain, Sternotomy
- Trial name
- BLOCKCABG (NCT07587320)
- Testing
- Multimodal Fascial Plane Block Package, Standard Postoperative Analgesia
- Where
- Turkey (Türkiye)
- Volunteers
- 88 people
- Sponsor
- Saglik Bilimleri Universitesi
Stiffness; Spine, Mobility Limitation
Comparison of Active Isolated Stretching Versus Myofascial Release of Knee Joint in Office Workers
"Office workers often spend long hours sitting, which can lead to stiffness and reduced mobility. By studying these two techniques AIS and MFR, we can determine which one is more effective in helping office workers to improve…
- Trial name
- NCT06352450
- Testing
- Active isolated stretching (AIS), Myofascial release (MFR)
- Where
- Pakistan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Superior University
Pneumonia, Bacterial
Prevalence and Serotype of Streptococcus Pneumoniae Hospitalized Adult With Community-Acquired Pneumonia
Streptococcus Pneumoniae is one of the etiology in severe CAP and accounts for about 60-75% of cases and is likely to be the leading cause of unknown etiologic pneumonia.
- Trial name
- HACAP (NCT05173727)
- Where
- Indonesia
- Volunteers
- 355 people
- Sponsor
- Dr Cipto Mangunkusumo General Hospital
LUMBAR STENOSIS
Surgical Decompression Associated With Physical Therapy and Physical Therapy Isolated in Patients With Lumbar Stenosis.
Stenosis of symptomatic lumbar canal is presented as a series of degenerative changes affecting the various vertebral segment structures, including: a joint zigoapofisária, yellow ligament, the articular capsule and the…
- Trial name
- Stenosis (NCT02879461)
- Testing
- LUMBAR DESCOMPRESSION
- Where
- Brazil
- Volunteers
- 62 people
- Sponsor
- Federal University of São Paulo
Cancer
Clinical Validation of a Microfluidic Device for Isolation and Molecular Characterization of Circulating Tumor Cells
To evaluate the efficiency of a microdevice for circulating tumor cells isolation and to correlate the circulating titre with response and progression.
- Trial name
- CTC (NCT01022723)
- Where
- Singapore
- Volunteers
- 817 people
- Sponsor
- National Cancer Centre, Singapore
Assessment of Safety of Laser Balloon Ablation, Assessment of Procedural Times of Laser Ballon Ablation
Single-Laser PVI: Single-encirclement Laserballoon Ablation for Pulmonary Veins Isolation
To assess the efficacy of laser balloon ablation of atrial fibrillation (AF) without verification of electrical isolation of pulmonary veins using implantable loop recorder. This is a prospective and single-center study.
- Trial name
- SingleLaser (NCT04165642)
- Testing
- Laser ballon ablation for Pulmonary vein isolation
- Where
- Italy
- Volunteers
- 82 people
- Sponsor
- IRCCS Policlinico S. Donato
Impaired Glucose Tolerance, Cardiovascular Disease
The DREAM (Diabetes Reduction Assessment With Ramipril and Rosiglitazone Medication) Trial
The purpose of this study is to determine if ramipril and/or rosiglitazone prevent the onset of type 2 diabetes.
- Conditions
- Impaired Glucose Tolerance, Cardiovascular Disease, Glucose Metabolism Disorders
- Trial name
- NCT00095654
- Testing
- Ramipril, Rosiglitazone
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- Gerstein, Hertzel, MD
Growth Hormone Deficiency
Isolated Growth Hormone Deficiency and Amennorrhea
This is a case report of a 14-year old female with no menstruation history.
- Trial name
- NCT05448924
- Testing
- Hormone panel tests
- Where
- Indonesia
- Volunteers
- 1 people
- Sponsor
- Universitas Padjadjaran
Atrial Fibrillation
aMAZE Study: LAA Ligation Adjunctive to PVI for Persistent or Longstanding Persistent Atrial Fibrillation
This study is a prospective, multicenter, randomized (2:1) controlled study to evaluate the safety and effectiveness of the LARIAT System to percutaneously isolate and ligate the Left Atrial Appendage from the left atrium as an…
- Trial name
- aMAZE (NCT02513797)
- Testing
- LARIAT + PVI, Pulmonary Vein Isolation
- Where
- 53 sites in United States
- Volunteers
- 600 people
- Sponsor
- AtriCure, Inc.
Social Isolation, Social Support (Formal and Informal)
A Personalized Reminder Information and Social Management System
Although technology offers great potential for enhancing the health and well-being of older adults, robust studies are needed to quantify the value of technology and further the investigators understanding of barriers to…
- Conditions
- Social Isolation, Social Support (Formal and Informal), Well-being/Quality of Life
- Trial name
- PRISM (NCT01497613)
- Testing
- PRISM C: Computer Condition, PRISM B: Notebook Condition
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University of Miami
Dystonia
The Dystonia Coalition Natural History and Biospecimen Repository for Isolated Dystonias
Dystonia is a disorder characterized by excessive involuntary contraction of muscles with repetitive and patterned movements. The isolated dystonias are the most common type of dystonia and include Limb dystonias (like writer's…
- Trial name
- DCP (NCT01373424)
- Where
- 42 sites in United States, Australia and 5 more
- Volunteers
- 3,265 people
- Sponsor
- Emory University
Cognitive Disorders
Single-center Prospective Longitudinal Study of Taste in Patients With Cognitive Disorders at Different Stages of Severity (Isolated Cognitive Complaint, Minor or Major Neurocognitive Alzheimer-type Disorders) by Analysis of Gustatory Evoked Potentials
The aim of the MAPEG 2 study is to explore gustatory function and to follow its evolution in the 4 following groups of participants: Healthy subjects Participants with isolated cognitive complaint Participants with minor…
- Trial name
- MAPEG 2 (NCT05888961)
- Testing
- Blood samples, Interviewing the subject and scales, Neurocognitive evaluation
- Where
- France
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire Dijon
Craniometaphyseal Dysplasia
Genetic and Functional Analysis of Craniometaphyseal Dysplasia (CMD)
CMD can be inherited in an autosomal dominant or recessive trait. CMD may also be caused by de novo mutations. The goal of this study is to identify genes and regulatory elements on chromosomes that are the cause for CMD.
- Trial name
- CMD (NCT01630460)
- Where
- United States
- Volunteers
- 600 people
- Sponsor
- UConn Health
Dystonia
A Study to Evaluate the Efficacy, Safety, and Tolerability of VIM0423 in Individuals With Isolated Dystonia
Stride Dystonia is a randomized, double-blind, placebo-controlled study to evaluate the efficacy, safety, and tolerability of VIM0423 in individuals with isolated dystonia.
- Trial name
- NCT07304089
- Testing
- VIM0423
- Where
- 45 sites in United States, Canada
- Volunteers
- 100 people
- Sponsor
- Vima Therapeutics
Atrial Fibrillation
Ground-Breaking Electroporation-based Intervention for PERSistent Atrial Fibrillation Treatment (BEAT PERS-AF)
BEAT AF is a randomized controlled trial aiming to assess the efficacy and the safety of pulsed field energy in persistent AF ablation
- Trial name
- BEAT PERS-AF (NCT05418725)
- Testing
- PVI and Linear lesion using PEF, PVI and Linear lesion using CFRF
- Where
- 9 sites in Austria, Belgium and 3 more
- Volunteers
- 83 people
- Sponsor
- University Hospital, Bordeaux
Depressive Symptoms, Aging
Digital Gaming Intervention for Older People in Long-term Care
Older people in long-term care (LTC) are often less physically active than their community-dwelling peers. Low physical activity level is associated with more symptoms of anxiety and depression as well as with lower physical…
- Conditions
- Depressive Symptoms, Aging, Loneliness, Sedentary Behavior
- Trial name
- NCT06018974
- Testing
- Yetitablet gaming
- Where
- Finland
- Volunteers
- 49 people
- Sponsor
- University of Oulu
Parkinson Disease
Randomized Clinical Trial in Parkinson's Disease Patients Using Pluripotent Adipose Stem Cells (PASCs)
The purpose of this study is to assess the safety and efficacy of allogenic pluripotent stem cells isolated from adipose tissue (PASCs) in patients with Parkinson's Disease.
- Trial name
- NCT06141317
- Testing
- PASC transplantation (25 million PASCs/patient), Control
- Where
- 2 sites in Costa Rica
- Volunteers
- 40 people
- Sponsor
- ClusterXStem-Costa Rica
Social Isolation, Aging
Evolution and Adaptation to Caregiver of a Socio-geriatric Evaluation
With the COVID-19 pandemic, elderly people (EP) living at home have seen their health deteriorated, thus increasing their needs in support and care.
- Trial name
- ESOGER (NCT05062590)
- Testing
- Recommendations
- Where
- Canada
- Volunteers
- 234 people
- Sponsor
- Centre integre universitaire de sante et de services sociaux du Centre-Sud-de-l'Île-de-Montréal
Endometriosis
Endometriosis and Quality of Life Assessed by EHP 30
Assessment of the quality of life for patients suffering from isolated endometriosic lesion of utero-sacral ligaments diagnosed by MRI, before and after surgical treatment by using French version of Endometriosis Health Profile…
- Trial name
- ENDOLUS (NCT03981991)
- Where
- France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Grenoble
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