Clinical trials: Itching
Pruritus
Acupuncture for Prevention of Itch in Caesarean Section
This study aims to determine the effectiveness of using a commercially available acupuncture stud at the LI11 acupuncture point at reducing the severity of itch caused by intrathecal diamorphine in elective caesarean section.
- Trial name
- NCT03458572
- Testing
- Seirin Pyonex press needle acupuncture
- Where
- United Kingdom
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Sheffield Teaching Hospitals NHS Foundation Trust
Peripheral Analgesic and Anti-itch
Pharmacokinetics, Mass Balance, and Metabolism of [14C]HSK21542 in Healthy Adult Male Volunteers.
This is a single-center, nonrandomized, and open design study to investigate the pharmacokinetics, mass balance, metabolism and excretion of HSK21542 in healthy male subjects.
- Trial name
- NCT05835934
- Testing
- [14C]HSK21542
- Where
- China
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Haisco Pharmaceutical Group Co., Ltd.
Lichen Simplex Chronicus
A Phase I Clinical Trial to Evaluate the Single Dose Ascending and Food Effects of PG-033 in Healthy Adults
The goal of this study is to evaluate the safety, tolerability and pharmacokinetics (PK) profiles of single ascending oral doses(SAD) of PG-033 by directly comparing it with placebo.
- Trial name
- NCT07013097
- Testing
- PG-033
- Where
- China
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Prime Gene Therapeutics Co., Ltd.
Pruritus
Does Indoxyl Sulfate Have a Role in Uremic Pruritus?
Itching is a widespread and disturbing complain from patients with chronic kidney disease (CKD); epidemiologic data have suggested that approximately 40% of patients with end-stage renal disease experience moderate to severe…
- Trial name
- NCT05634083
- Testing
- Uremic pateints with itching
- Where
- 2 sites in Egypt
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Benha University
Intrahepatic Cholestasis of Pregnancy
Unraveling the Pathogenesis of Pruritus in Intrahepatic Cholestasis of Pregnancy
This study hopes identify the main pruritogens of ICP pruritus and provide new insights for the diagnosis, prediction, and treatment of ICP.
- Trial name
- NCT06366659
- Where
- 2 sites in China
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Peking University
Psoriasis, Healthy
Brain Changes in Psoriasis After Secukinumab Treatment
The purpose of this study is to assess the effect of a biologic drug targeting the Interleukin (IL)-17 pathway (secukinumab) on brain plasticity and examine whether the plastic changes correlate with the improvement of perception…
- Trial name
- NCT04717466
- Testing
- Secukinumab
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Miami
Cutaneous T-Cell Lymphoma
Recalcitrant Pruritus in Cutaneous T-Cell Lymphoma
The purpose of this study is to define the mechanisms that underlie the refractory pruritus (itch) in Cutaneous T-Cell Lymphoma (CTCL).
- Trial name
- CTCL (NCT00863395)
- Testing
- skin biopsy
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Pruritus of the Scalp
In-Use Test of a Cosmetic Product in Subjects With Chronically Itchy Scalp
The aim of the study is to evaluate the tolerance of the Shampoo (WO 5101) on the scalp by a dermatologist and by the subjects themselves after four weeks of regular product use.
- Trial name
- NCT03630107
- Where
- Germany
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Dr. August Wolff GmbH & Co. KG Arzneimittel
Athlete Foot
Neurodynamics to Improve Jump Functionality in Trampoline Jump Gymnasts
The goal of neurodynamics is to restore homeostasis of peripheral nerves. In the current context there is varied evidence that links neurodynamics with clinical pain treatments or different pathologies, but little evidence…
- Trial name
- NCT04289857
- Testing
- Neurodynamic training
- Where
- Spain
- Volunteers
- healthy volunteers welcome
- Sponsor
- Investigación en Hemofilia y Fisioterapia
Diet Habit, Body Weight
Sports Nutrition Assessment Program
The NutriEvalUA program is an observational study aiming to assess the nutritional status, body composition, hydration, physical activity, and health indicators in university athletes.
- Conditions
- Diet Habit, Body Weight, Athlete Foot
- Trial name
- NutriEvalUA (NCT07104669)
- Testing
- diet, Physical activity, body composition
- Where
- Spain
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Alicante
Scald Burn, Itching
Comparison of the Effects of Liquid Vaseline and Olive Oil on Itching and Scarring in Scald Burns
Pain, itching, hypertrophic scar formation after wound healing in burn patients complications, sleep disturbances in patients, anxiety, depression, and daily life It may disrupt activities and deterioration in quality of life.
- Conditions
- Scald Burn, Itching, Hypertrophic Scarring
- Trial name
- NCT06104540
- Testing
- Experimental I liquid vaseline groups, Experimental II extra virgin olive oil groups, Control Croup
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Ankara Yildirim Beyazıt University
Pruritus
Effect of Granisetron on Morphine Induced Pruritus in Cesarean Section
Neuraxial anesthesia, which includes epidural anesthesia and intrathecal anesthesia, is a frequent anesthetic approach for caesarean delivery and other lower abdominal and lower limb anesthetic procedures.
- Trial name
- NCT03483870
- Testing
- Morphine Sulfate, Granisetron
- Where
- Egypt
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Assiut University
Dermatitis, Atopic
Investigation of Topical SB705498 on Healthy Volunteers
A two part, randomized, double-blind, placebo controlled study to investigate the effects of topical doses of SB705498 in healthy volunteers.
- Trial name
- NCT01673529
- Testing
- SB705498
- Where
- United Kingdom
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Xerosis Cutis, Dry Skin
Enhancing SKIN Health and Safety in Aged CARE
Aged long-term care receivers are affected by various adverse skin conditions like pressure ulcers, incontinence-associated dermatitis, dryness, intertrigo and many more.
- Conditions
- Xerosis Cutis, Dry Skin, Pruritus, Pressure Ulcer
- Trial name
- SKINCARE (NCT03824886)
- Testing
- Implementation of skin care algorithm
- Where
- 2 sites in Germany
- Volunteers
- 405 people, healthy volunteers welcome
- Sponsor
- PD Dr. Jan Kottner
Histamine, Cowhage
Investigation of the Effects of Sleep Fragmentation on Itch and Pain Sensitivity
In This experiment, the investigators would like to test following hypotheses regarding the influence of sleep fragmentation on itch: To investigate similarity and differences between itch and pain by comparing the effect of…
- Conditions
- Histamine, Cowhage, Sleep Fragmentation
- Trial name
- NCT06081946
- Testing
- Histamine, Cowhage
- Where
- Denmark
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Aalborg University
Healthy Volunteers
The Effect of Low Level Light Therapy on Histamine- and Mucuna Pruriens-induced Pruritus in Healthy Volunteers
This is a prospective, double-blind, randomised, sham-controlled study whose primary aim is to test whether LLLT changes the intensity of itch after histamine application in healthy volunteers compared to sham application.
- Trial name
- NCT05369338
- Testing
- Low Level Light Therapy
- Where
- Austria
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Medical University of Graz
Individual Adjustment, Itch; Athlete
Electromyographic Analysis And Body Balance In The Use Of Athletes After Cryotherapy By Immersion Ankle
The influence of cryotherapy on ankle motor control and balance of athletes is controversial. The aim of this study is to assess the neuromuscular response of the dominant leg and body balance basketball athletes after…
- Trial name
- NCT01870414
- Testing
- cryotherapy by immersion
- Where
- Brazil
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Onychomycosis, Tinea Pedis
Spread of Dermatophytes Among Families
The objective is to demonstrate person-to-person spread of dermatophytes of the skin and nails among family members, as measured by fungal culture and DNA typing of the dermatophytes isolated.
- Trial name
- NCT00233493
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University Hospitals Cleveland Medical Center
Allergy, Anxiety
The Effects of Virtual Reality and Music on Pain, Anxiety, Itching, and Vital Signs
Aim: This study aimed to examine the effects of virtual reality and music on pain, anxiety, itching, and vital signs of children during a skin prick test and evaluation.
- Conditions
- Allergy, Anxiety, Pain, Itching
- Trial name
- NCT06479967
- Testing
- The VR glasses group, the music group
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Uludag University
Chronic Spontaneous Urticaria (CSU), Hidradenitis Suppurativa (HS)
SKIN Disease Profiling by an Exploratory, pRospective, Biomarker Study in dermatoloGY Practice (SKINERGY)
The goal of this observational study is to comprehensively profile six immune-mediated inflammatory diseases, including atopic dermatitis (AD), plaque psoriasis (PSO), hidradenitis suppurativa (HS), cutaneous T-cell lymphoma…
- Conditions
- Chronic Spontaneous Urticaria (CSU), Hidradenitis Suppurativa (HS), Psoriasis (PsO), Atopic Dermatitis (AD)
- Trial name
- SKINERGY (NCT07021495)
- Where
- 8 sites in Netherlands
- Volunteers
- 840 people, healthy volunteers welcome
- Sponsor
- Leiden University Medical Center