Clinical trials: Ivf
Infertility
Impact of Sequential Double Embryo Transfer on Live Birth Rates: A Case-Control Study.
The main aim of this study is to evaluate the impact and identify potential indications for sequential double embryo transfer (SEQ-ET) in couples undergoing assisted reproductive technology (ART).
- Trial name
- SEQ-ET (NCT07499453)
- Where
- France
- Volunteers
- 778 people, healthy volunteers welcome
- Sponsor
- Hopital Pierre Rouques - Les Bluets
Infertility, Female, AMH
AMHR2 Polymorphism in Blood and Granulosa Cells in Unexplained Infertility
There are various known parameters for assessing ovarian reserve, including ovarian volume, antral follicle count, follicle stimulating hormone (FSH) and Inhibin B at the beginning of the menstrual cycle, as well as…
- Conditions
- Infertility, Female, AMH, IVF
- Trial name
- NCT05592730
- Testing
- AMHR2 polymorphism in blood, AMHR2 polymorphism in granulosa cell
- Where
- Turkey (Türkiye)
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
In Vitro Fertilization, Assisted Reproductive Techniques
Optimizing IVF Treatment - the Impact of Time-lapse Culture and Preimplantation Factor (PIF) on Embryo Development.
The aims of this study are to evaluate: 1. the possible effect of time-lapse culture from day zero (day of oocyte retrieval) on fertilisation rates and embryo quality in standard IVF. 2.
- Trial name
- NCT02222831
- Testing
- Day 0 denudation and time lapse culture on IVF-oocytes.
- Where
- Denmark
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Regionshospitalet Viborg, Skive
Simulation Training, IVf
Benefits of an Oocyte Pickup Simulation Training Program
The primary objective of this study was to evaluate oocyte pick up simulation training program for teaching residents. The secondary objectives were to evaluate resident satisfaction and the overall current state of oocyte pick…
- Conditions
- Simulation Training, IVf, Education
- Trial name
- NCT04130139
- Testing
- oocyte pick up simulator
- Where
- France
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- University Hospital, Angers
Infertility
Prospective, Randomized Trial Comparing ICSI to Insemination for Non-Male Factor Patients Undergoing PGT-A
Intracytoplasmic sperm injection (ICSI) is a procedure performed during in vitro fertilization (IVF) in which a single sperm is injected directly into an oocyte.
- Trial name
- NCT05548101
- Testing
- ICSI
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Texas Fertility Center
Semen Analysis, ICSI
Evaluating the Utility of Implementing Microfluids for Sperm Preparation Compared to Conventional Method of Density Gradient Centrifugation in a PGT-A Program: a Sibling Oocyte Study
In assisted reproductive technology (ART), sperm preparation aims to select the most viable sperm for ICSI. Unlike conventional methods like density gradients or sperm washing, microfluidic techniques mimic natural selection in…
- Conditions
- Semen Analysis, ICSI, PGT-A
- Trial name
- NCT07093619
- Testing
- FERTILE Plus
- Where
- United Arab Emirates
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- ART Fertility Clinics LLC
Recurrent Implantation Failure in Setting of Artifically Prepared Endometrium
Trial of Endometrial Scratch Prior to Frozen Embryo Transfer in Patients With Recurrent Implantation Failure
Patients with a history of recurrent implantation failure who are planning a frozen embryo transfer (FET) are enrolled into the program.
- Trial name
- NCT03157765
- Testing
- endometrial biopsy
- Volunteers
- healthy volunteers welcome
- Sponsor
- Brown Fertility
Infertility
Application of Two Different Synthetic Sequential Media for the Human IVF-Embryo Transfer (IVF-ET) Program
Quality-controlled commercial media have been used in many in-vitro fertilization (IVF) laboratories. However, commercial media are costly and difficult to compare directly because their exact compositions are not clearly…
- Trial name
- NCT01356238
- Testing
- MRC media, Sydney IVF media
- Where
- South Korea
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- Maria Fertility Hospital
IVF, Frozen Embryo Transfer (FET)
Maternal Cardiovascular Adaption to Pregnancy in IVF Patients Following Frozen Embryo Transfer (FET)
Aim of the study is to explore the effect of a lacking corpus luteum on maternal cardiovascular and metabolic adaption to pregnancy by the use of magnetic resonance imaging (MRI).
- Conditions
- IVF, Frozen Embryo Transfer (FET), Cardiovascular Adaption, Magnetic Resonance Imaging (MRI)
- Trial name
- NCT06471140
- Testing
- magnetic resonance imaging (MRI)
- Where
- Denmark
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Aalborg University Hospital
Infertility
Derivation of New Human Embryonic Stem Cell Lines Lines for Clinical Use
Human embryonic stem cells (hESCs) are isolated from the early human embryo and have the capability to proliferate indefinitely in culture and to develop into nearly every cell of the human body.
- Trial name
- NCT00353197
- Where
- Israel
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
No Condition
Comparison of Clinical Outcomes Between IVM and Minimal Stimulation IVF in Patients With PCOS
Polycystic ovarian syndrome (PCOS) is most common endocrinologic disease in women of reproductive age with incidence of 6.6 ~ 8%.
- Trial name
- NCT03134482
- Testing
- IVM, Minimal stimulation IVF
- Where
- 2 sites in South Korea
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- CHA University
IVF
Speculum Insertion During Embryo Transfer
Lubrication gels are widely used in numerous gynecologic procedures in order to ease the insertion of speculum and visualize the cervix.
- Trial name
- NCT06210451
- Testing
- Sterile water-based gel
- Where
- Israel
- Volunteers
- 416 people, healthy volunteers welcome
- Sponsor
- Wolfson Medical Center
Female Infertility, Ovarian Insufficiency
Efficacy Study Comparing the Effect of Clomiphencitrate to an Antagonist Protocol
The aim of this study is to assess the oocyte yield of infertile women with suspected or known poor ovarian reserve (POR) undergoing a GnRH antagonist protocol for IVF with Merional® starting either with a low (150 IU) or a high…
- Trial name
- CANTAPOR (NCT01577472)
- Testing
- High Dose Clomiphencitrat, Low Dose Clomiphencitrat
- Where
- Switzerland
- Volunteers
- 117 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Female Infertility
Impact of Clomiphene Citrate Administration During the Early Luteal Phase on Endocrine Profile in IVF Cycles
The purpose of this study is to evaluate the effect on LH levels of the 5-day CC administration during luteal phase in oocyte donors, to investigate whether the CC corrects the suppressed LH levels in the luteal phase and whether…
- Trial name
- CLOFA (NCT01791751)
- Testing
- Clomifene Citrate
- Where
- Spain
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Fundació Privada Eugin
Healthy Volunteers
Early Environmental and Maternal Determinants of Airway Inflammation in Wheezing Disorders in Infants
This study collects data on microbiological, genetic and environmental factors, as well as lung function parameters (e.g. spirometry, body plethysmography, lung-MRI) to assess the complex interaction of predisposing risk factors…
- Trial name
- NCT04286464
- Testing
- No intervention
- Where
- Switzerland
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Women Diagnosed With Cancer, Egg Donors
Oocyte Cryopreservation by Slow Freezing and Vitrification
This study seeks to evaluate whether the vitrification technique, as compared to the more traditional slow-cooling technique, leads to higher rates of successful thawing, fertilization, implantation and delivery.
- Conditions
- Women Diagnosed With Cancer, Egg Donors, Single Women, Failed Sperm Procurement in IVF
- Trial name
- NCT01223105
- Testing
- slow freeze, Vitrification
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Reproductive Medicine Associates of New Jersey
Infertility
In Vitro Maturation (IVM) of Human Oocytes
The objectives of this study are to evaluate the clinical efficacy of Natural in vitro Fertilization and in vitro maturation.
- Trial name
- IVM (NCT01550861)
- Testing
- in vitro maturation, Polar Body Biopsy with preimplantation genetic screening
- Where
- United States
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Fertility
Effect of GnRH Antagonist vs Agonist Long on IVF Outcome, Peak Estradiol Level,and Duration of Stimulation
The purpose of this study is to determine if utilizing GnRH antagonists versus agonist long protocol during controlled ovarian stimulation (COH) with human-derived gonadotropins for assisted reproduction affects IVF outcome, peak…
- Trial name
- NCT01669291
- Testing
- Bravelle and Menopur, Agonist, Antagonist
- Where
- United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Main Line Fertility Center
Infertility Female
IVM for Patients With Low Ovarian Response. Does it Improve IVFoutcomes and Does it Improve the Following IVF Cycle?
Poor ovarian response (POR) is one of the major therapeutic challenges in in vitro fertilization. Several therapeutic approaches for POR have been explored; yet, a single effective strategy has not yet been established.
- Trial name
- NCT02498210
- Testing
- In Vitro Maturation Procedure
- Where
- Israel
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Infertility
Discarded Materials Study
Use of discarded embryos to advance laboratory expertise and technology in the area of human embryo development and assisted reproductive technologies
- Trial name
- NCT01219335
- Where
- United States
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Reproductive Medicine Associates of New Jersey