Clinical trials: Ivf
Fertilization in Vitro
The Comparison of Granulosa Cell Apoptosis Rates With or Without Luteinizing Hormone Administration in Poor Responders.
In Zeynep Kamil Women and Children's Education and Research Hospital which is a tertiary referral hospital, the investigators perform microdose flare-up gonadotropin-releasing hormone (GNRH) analogue or GNRH antagonist protocol…
- Trial name
- NCT03527823
- Where
- Turkey (Türkiye)
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Sebnem Alanya Tosun
Midazolam Overdose
Measurement of Midazolam Levels in Follicular Fluid
To determine the impact of Midazolam levels in follicular fluid on morpho-kinetics and morpho-genetics. The reason to measure Midazolam levels in larger size follicles in this study is to maximize the chances to get a mature…
- Trial name
- NCT03049293
- Testing
- Midazolam
- Where
- United Arab Emirates
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- ART Fertility Clinics LLC
Infertility
Ultrashort GnRH Agonist/Antagonist Versus GnRH Antagonist IVF
The purpose of this study is to evaluate the appropriate controlled ovarian hyperstimulation (COH) protocol in good prognosis patients undergoing IVF treatment.
- Trial name
- NCT02173977
- Testing
- ARM A- Agonist/Antagonist protocol, ARM B- Antagonist protocol
- Where
- Israel
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Ovarian Stimulation
Clomiphene Citrate (CC)/Gonadotropin/Gonadotropin Releasing Hormone (GnRH) Antagonist Versus Gonadotropin/GnRH Agonist
Objective: To compare the efficacy of using mild ovarian stimulation protocol and conventional stimulation protocol in IVF outcome. Design: Prospective randomized trial Setting: University IVF setting.
- Trial name
- NCT00830492
- Testing
- clomiphene citrate, Ultrasound, GnRH antagonist
- Where
- Iran
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Yazd Research & Clinical Center for Infertility
Infertility
Clinical Outcomes of Slow Developing Blastocysts
This study evaluates which transfer strategy will result in a higher probability of pregnancy in patients whose single best day 5 embryo resulting from an IVF cycle is classified as expansion grade <4 by Gardner and Schoolcraft…
- Trial name
- LATEBLOOM (NCT03360097)
- Testing
- Frozen Embryo Transfer
- Where
- Spain
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Fundacion Dexeus
in Vitro Fertilization, Poor Responder
Dopamine D-2 Antagonist Use in Poor Responders in IVF: a Randomized Controlled Trial
Metoclopramide is a dopamine D2 receptor antagonist with antiemetic and gastrokinetic properties which has been approved for use in pregnant women.
- Trial name
- NCT02262923
- Testing
- metoclopramide
- Where
- Canada
- Volunteers
- healthy volunteers welcome
- Sponsor
- Mount Sinai Hospital, Canada
Infertility, Sterility, Reproductive, Reproductive Sterility, Sterility, Subfertility, Sub-Fertility
Complex Fertility Awareness Study - Hungary
The goal of this observational study is to investigate integrative fertility awareness and its impact on assisted reproductive techniques (ART) in Hungary.
- Trial name
- FAIR-HU (NCT06795568)
- Volunteers
- 750 people, healthy volunteers welcome
- Sponsor
- University of Pecs
Pregnancy, Ovarian
Long Antagonist Protocol for IVF With Single Luteal Dose of Degarelix
A prospective study of three different doses of Degarelix in late luteal phase of women undergoing ovarian stimulation for IVF
- Trial name
- NCT03240159
- Testing
- Degarelix
- Where
- Greece
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Assisting Nature
Infertility
Freeze All on Oocyte Maturatin by Gonadotropin Agonist Versus Human Chorionic Gonadotroipin
Estradiol valerate in the form of cycloprogenova™ (white tablet only) was started on day 2 or 3 of cycle with oral dose 4 mg divided on 2 doses in addition to Aspocid 75 mg once daily with folic acid 500 mcg once daily.
- Trial name
- NCT04749979
- Testing
- Agonist (decapeptyl ), HCG ( eg. Choriomon )
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Aljazeera Hospital
Infertility, Female, Web
Responsive Web-based Roadmap (InT-mAp) in Infertility Treatment
Infertility affects approximately 48 million couples and 186 million individuals globally, and it has biological, psychosocial, and economic problems in couples.
- Conditions
- Infertility, Female, Web, Anxiety, IVF
- Trial name
- InT-mAp (NCT05890625)
- Testing
- On going treatment, InT-mAp
- Where
- Turkey (Türkiye)
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Maltepe University
Infertility Assisted Reproductive Technology, Oocyte Retrieval
ART Cycle Outcomes When Only 1 to 3 Oocytes Are Retrieved
This is a monocentric retrospective observational study. The study focuses on the women who underwent Assisted Reproductive Technology (ART) cycles with poor ovarian response (POR), defined as <4 oocytes retrieved.
- Trial name
- POR (NCT06950476)
- Testing
- Oocyte Retrieval
- Volunteers
- 3,761 people, healthy volunteers welcome
- Sponsor
- Istituto Clinico Humanitas
ARTIFICIAL INTELLIGENCE (AI) APPLICATIONS IN REPRODUCTIVE MEDICINE
ARTIFICIAL INTELLIGENCE IN REPRODUCTIVE MEDICINE
Many studies have been published investigating the use of AI as an unbiased, automated approach to embryo assessment. This review will summarize the recent AI advancements in the IVF field.
- Trial name
- AI in ART (NCT05699850)
- Testing
- ARTIFICIAL INTELLIGENCE (AI)
- Where
- 2 sites in Egypt
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Al Baraka Fertility Hospital
IVF
Uterine Lesions and Their Association to Invitro Fertilization(IVF) or Intracytoplasmic Sperm Injection(ICSI) Outcome
1. To study the effect of uterine wall , intracavitary , cervical as well as cervical canal lesion on the outcome of IVF/ICSI cycle. 2. To establish a score for prediction of IVF/ICSI cycle success .
- Trial name
- NCT04939376
- Testing
- IVF
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- Assiut University
Aneuploidy
Polar Body Biopsy for Preimplantation Genetic Screening
People with infertility undergoing in vitro fertilization (IVF) can test the embryos using a method called preimplantation genetic screening (PGS) before they are implanted in the uterus to possibly increase their chances of…
- Trial name
- Polar Body (NCT01574404)
- Testing
- Polar body biopsy with PGS
- Where
- United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Control Media Only, Study hCG and Media
Intrauterine Human Chorionic Gonadotropin at the Time of Embryo Transfer
Techniques to improve pregnancy and delivery rates in IVF cycles have focused not only on the embryos transferred, but also the conditions in the uterus at the time of transfer and implantation.
- Trial name
- NCT01643993
- Testing
- hCG at the Time of Embryo Transfer, Control
- Where
- 2 sites in United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Reproductive Medicine Associates of New Jersey
Poor Ovarian Response
Novel Therapy for Poor Responders Management
Unfortunately for some infertile women, gonadotrophin administration results in a desultory ovarian response. While this is commonly due to diminished ovarian reserve, as indicated by advanced age and/or elevated basal day 3 FSH…
- Trial name
- NCT04310293
- Testing
- Femara,Grotwth hormone,HMG
- Where
- Bahrain
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Al Baraka Fertility Hospital
Infertility, Female
Daytime Profile of Salivary Progesterone
The aim of this study is to perform a 12-hour profile of free saliva progesterone during the luteal phase after fresh and frozen embryo transfer.
- Trial name
- NCT03725904
- Testing
- Progesterone analysis in saliva
- Where
- Denmark
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Peter Humaidan
Ovarian Stimulation, Reproductive Techniques, Assisted
The Effect of Dual Trigger for Final Oocyte Maturation on IVF/ICSI Outcomes in Patients With Suboptimal Ovarian Response
Recently, in patients with a suboptimal ovarian response, a study of the role of adding a single dose of GnRH agonist to a standard dose of hCG to initiate final oocyte maturation has also been studied. Griffin et al.
- Trial name
- NCT04549649
- Testing
- Dual triggering
- Where
- Iran
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Royan Institute
Infertility, Pain
Acupuncture for Symptom Control During Assisted Reproductive Treatments Procedures
Rationale for conducting the experiment: Israel performed IVF treatments since 1980. Although ART (Advanced Reproductive Treatments) have evolved over the years implantation and pregnancy rates have not met the expectations yet.
- Trial name
- NCT02611726
- Testing
- Acupuncture
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Bnai Zion Medical Center
Subfertility
RCT on the Effect of Endometrial Injury on Ongoing Pregnancy Rate in Subfertile Women Undergoing IVF
Implantation failure remains one of the major factors limiting success in IVF treatment. It was postulated that the local injury to endometrium induces secretions of cytokines and growth factors such as leukemia inhibitory…
- Trial name
- NCT01977976
- Testing
- Endometrial aspiration by pipelle
- Where
- Hong Kong
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong