Clinical trials: Ivf
IVF
Dual Trigger, Urinary HCG or Recombinant HCG, Which is the Best !?
a comparative study among dual trigger, urinary HCG and recombinant HCG regarding the outcome of ICSI- antagonist cycles
- Trial name
- NCT04265495
- Where
- Bahrain
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Al Baraka Fertility Hospital
Effectiveness of Isoamyl-2-cyanoacrylate With and Without Ethiodized Oil in Occluding Hydrosalpinx Prior to IVF
Hysteroscopic Tubal Occlusion Using Amacrylate With or Without Lipidol in Patients With Hydrosalpinx Prior to IVF
Hysteroscopic tubal occlusion using iso-amyl- 2-cyanoacrylate with or without Ethiodized oil (Lipidol) in patients with hydrosalpinx prior to IVF
- Trial name
- NCT06130072
- Testing
- iso-amyl- 2-cyanoacrylate., iso-amyl- 2-cyanoacrylate mixed with Ethiodized oil
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Infertility, Pregnancy Related
The Impact of Vaginal Intercourse on Pregnancy Rates After Frozen Embryo Transfer
This study aims to evaluate whether allowing unprotected vaginal intercourse 24 hours after frozen embryo transfer will result in higher ongoing clinical pregnancy rates in comparison to having participants abstain from…
- Conditions
- Infertility, Pregnancy Related, IVF
- Trial name
- NCT03974295
- Testing
- Vaginal unprotected intercourse
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- University of South Florida
Metformin, Prediabetes
Effect of Metformin on Healthy Live Birth in Women With Prediabetes
To evaluate the efficacy and safety of metformin pretreatment on reproductive outcomes in infertile women with prediabetes.
- Conditions
- Metformin, Prediabetes, In-Vitro Fertilization
- Trial name
- MELT-PreDM (NCT06064669)
- Testing
- Metformin pretreatment before ovarian stimulation, Metformin pretreatment before endometrial preparation for frozen embryo transfer
- Where
- China
- Volunteers
- 988 people, healthy volunteers welcome
- Sponsor
- Shandong University
Infertility, IVF
Sex Selection of Human Spermatozoa
This study aims to demonstrate a reliable method of selecting gender specific sperm. X-bearing spermatozoa and Y-bearing spermatozoa will be identified from the density gradient layers.
- Trial name
- NCT05500573
- Testing
- Sperm Sorting
- Where
- United States
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Infertility
The Derivation of Human Embryonic Stem Cell Lines From PGD Embryos
Human embryonic stem cells (hESCs) are isolated from the early human embryo and have the capability to proliferate indefinitely in culture and to develop into nearly every cell of the human body.
- Trial name
- NCT00353210
- Where
- Israel
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Pain, Postoperative, IVF
OPU-LUX: Virtual Reality for Pain and Anxiety Management During Oocyte Pick-up
In vitro fertilization (IVF) cycles are increasingly performed worldwide. Transvaginal oocyte pick-up (OPU) is a painful part of IVF. OPU in polyfollicular IVF is usually performed under sedation and pain relief.
- Trial name
- OPU-LUX (NCT05830513)
- Testing
- Virtual Reality
- Where
- Switzerland
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Luzerner Kantonsspital
Infertility (IVF Patients), Oocyte Retrieval
Impact of the Operator Performing Oocyte Retrieval on the Cumulative Live Birth Rate
This is a monocentric retrospective observational study. The study investigates the impact of the operator performing the oocyte retrieval on the cumulative live birth rate (CLBR).
- Trial name
- OPU-CLBR (NCT06933901)
- Testing
- Oocyte retrieval
- Volunteers
- 19,500 people, healthy volunteers welcome
- Sponsor
- Istituto Clinico Humanitas
Children Born After Assisted Reproductive Technologies, Health Status
Health Status of Children Born After Assisted Reproductive Technologies
The goal of this observational study is to study the features of psychophysical development and the morbidity patterns of children born after assisted pregnancy, and to identify the connection with the health status of mothers…
- Conditions
- Children Born After Assisted Reproductive Technologies, Health Status, Child Development
- Trial name
- NCT06094998
- Testing
- hemogram examination
- Where
- Kazakhstan
- Volunteers
- 252 people, healthy volunteers welcome
- Sponsor
- Kazakhstan's Medical University "KSPH"
Infertility, IVF
Health of Frozen Transferred Versus Fresh Transferred Children
In order to give strong recommendation on the efficacy and safety of fresh versus frozen embryo transfer, we conduct this study in order to investigate the physical and mental development of children from fresh versus frozen…
- Trial name
- NCT04099784
- Testing
- Developmental score according to The Ages & Stages Questionnaires®, Third Edition - ASQ®-3, Physical development and General Health, Developmental Red flags
- Where
- Vietnam
- Volunteers
- 255 people, healthy volunteers welcome
- Sponsor
- Mỹ Đức Hospital
Infertility
Randomized Controlled Trial Comparing Embryonic Quality in rFSH Versus hMG in IVF Protocol With GnRH Antagonist
rFSH and HMG are both used to controlled ovarian stimulation for patients submitted to IVF. However, there is a debate in the literature which one is better to induce ovulation in patients receiving GnRH antagonist to block…
- Trial name
- NCT02412904
- Testing
- rFSH, HMG
- Where
- Brazil
- Volunteers
- 188 people, healthy volunteers welcome
- Sponsor
- Hospital de Clinicas de Porto Alegre
Fertilization in Vitro
Poor Ovarian Responders Undergoing IVF Using Luteal Ovarian Stimulation Versus Follicular Ovarian Stimulation
The investigators attempted to compare the clinical outcomes and cumulus genes expression in poor ovarian responders undergoing luteal ovarian stimulation or follicular ovarian stimulation in in vitro fertilization cycles.
- Trial name
- NCT03238833
- Testing
- luteal ovarian stimulation, follicular ovarian stimulation
- Where
- Taiwan
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Kaohsiung Veterans General Hospital.
Anxiety, in Vitro Fertilization
Impact of Virtual Reality Before Oocytes Retrieval on Anxiety and Pregnancy Rate
The primary objective of this study is to evaluate the impact of a session of virtual reality (VR) with the objective of lowering the anxiety level on the clinical pregnancy rate following an In-vitro fertilisation (IVF)…
- Conditions
- Anxiety, in Vitro Fertilization, Virtual Reality
- Trial name
- NCT03064061
- Testing
- Virtual reality
- Where
- Belgium
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Infertility
Comapring Luteal Phase Support in IVF Patients Who Are at High Risk for Developing OHSS
The purpose of this study is to compare two luteal support protocols in In vitro fertilization patients (IVF) and are at risk of developing ovarian hyperstimulation syndrome (OHSS).
- Trial name
- NCT02827656
- Testing
- Decapeptyl, hCG luteal support
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Meir Medical Center
Uterine Adenomyosis, Recurrent Implantation Failure
Aromatase Plus GnRH Analogue Versus GnRH Analog Alone in Adenomyosis
With this study the investigators want to test which is the best medical treatment for symptomatic adenomyosis affecting women undergoing IVF and with previous implantation failure, between Aromatase inhibitor plus GnRH analog…
- Conditions
- Uterine Adenomyosis, Recurrent Implantation Failure, Menstrual Pain
- Trial name
- NCT03421639
- Testing
- GnRH analog (11.25mg Leuprolide acetate), Aromatase inhibitor and GnRH analog, Aromatase and GnRH analog (11.25mg Leuprolide acetate)
- Where
- 3 sites in Albania, Bulgaria and 1 more
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Centre for Endocrinology and Reproductive Medicine, Italy
INFERTILITY
Dual Triggering in Patients With a High Immature Oocyte Rate
In in vitro fertilization (IVF) cycles, even after adequate triggering, some patients present a high rate of immature oocytes retrieved after controlled ovarian stimulation.
- Trial name
- NCT02813239
- Testing
- hCG, hCG + GnRH agonist
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- IVI Madrid
Pain Intensity Assessment
Pain Relief in Women Undergoing Oocyte Retrieval (OR) With Electro-acupuncture (EA) or Conscious Sedation (CS) in a Single Assisted Reproduction Centre.
This study aims to determine whether one can replace pain relief in women undergoing oocyte retrieval (OR) using electro-acupuncture (EA) instead of conscious sedation (CS).
- Trial name
- EA (NCT07041632)
- Testing
- electro-acupuncture, Conscious sedation
- Where
- Singapore
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Singapore General Hospital
In Vitro Fertilization
A Study of the Effects of a Novel Ovarian Stimulation Regimen on Embryo Aneuploidy Rates in In Vitro Fertilization (IVF)
Background: By limiting the number of embryos transferred to the uterus to only a single embryo, the risk of multiple gestation can be reduced.
- Trial name
- NCT00866008
- Testing
- Ovarian stimulation
- Where
- Netherlands
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Bart CJM Fauser
Environmental Exposure, Assisted Reproductive Technology
Environmental and Behavioral Factors in Infertility and ART Outcomes
This large-scale study aims to understand how everyday environment and lifestyle may affect the success of fertility treatments like IVF.
- Conditions
- Environmental Exposure, Assisted Reproductive Technology, Prospective Study
- Trial name
- NCT07384676
- Testing
- plastic products, None exposure
- Where
- China
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- The Third Xiangya Hospital of Central South University
Bacterial Vaginosis
PNA FISH, PCR and Gram Staining for Detection of Bacterial Vaginosis - a Comparative Clinical Study in a Danish IVF Setting
The primary aim of the present study is to investigate the vaginal microbiota of infertile women with two novel molecular based diagnostic tests for Bacterial Vaginosis, a PNA FISH and a PCR method supported with conventional…
- Trial name
- NCT02042352
- Testing
- pH glove
- Where
- Denmark
- Volunteers
- 195 people, healthy volunteers welcome
- Sponsor
- Regionshospitalet Viborg, Skive