Clinical trials: Ivf
Azoospermia, IVF
Laser Assisted Sperm Selection of Viable Immotile Testicular Sperm in Azoospermic Infertile Men
This study aims to investigate the outcome of ICSI after using LAISS for selection of viable immotile testicular sperm in azoospermic infertile men. Patients will be randomly assigned to 2 groups.
- Trial name
- NCT04675164
- Testing
- Laser Assisted Immotile Sperm Selection, Hypo-osmotic Swelling Test
- Where
- Egypt
- Volunteers
- 168 people
- Sponsor
- Sohag University
Infertility, Female, Web
Responsive Web-based Roadmap (InT-mAp) in Infertility Treatment
Infertility affects approximately 48 million couples and 186 million individuals globally, and it has biological, psychosocial, and economic problems in couples.
- Conditions
- Infertility, Female, Web, Anxiety, IVF
- Trial name
- InT-mAp (NCT05890625)
- Testing
- On going treatment, InT-mAp
- Where
- Turkey (Türkiye)
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Maltepe University
Effectiveness of Isoamyl-2-cyanoacrylate With and Without Ethiodized Oil in Occluding Hydrosalpinx Prior to IVF
Hysteroscopic Tubal Occlusion Using Amacrylate With or Without Lipidol in Patients With Hydrosalpinx Prior to IVF
Hysteroscopic tubal occlusion using iso-amyl- 2-cyanoacrylate with or without Ethiodized oil (Lipidol) in patients with hydrosalpinx prior to IVF
- Trial name
- NCT06130072
- Testing
- iso-amyl- 2-cyanoacrylate., iso-amyl- 2-cyanoacrylate mixed with Ethiodized oil
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Infertility, Diminished Ovarian Reserve
The LUTEAL Trial: Luteal Stimulation vs. Estrogen Priming Protocol
Ovarian reserve defines the quantity and quality of the ovarian primordial follicular pool. Diminished ovarian reserve (DOR) indicates a reduction in the quantity of ovarian follicular pool to less than expected for age.
- Conditions
- Infertility, Diminished Ovarian Reserve, IVF
- Trial name
- NCT04447872
- Testing
- Timing of injectable gonadotropins
- Where
- United States
- Volunteers
- 142 people
- Sponsor
- Northwell Health
Infertility, IVF
Outcomes of 36 vs 38 Hour Intervals From Ovulation Trigger To Oocyte Pick-Up:A Multi-Center Randomized Controlled Trial
Women who undergo assisted reproduction technology (ART) treatment will be eligible for this study. The goal of this randomized clinical trial is to compare the outcomes of ART treatment between women who have 36 and 38 hours…
- Trial name
- NCT05803655
- Testing
- 36-hour duration between ovulation triggering and oocyte pick-up procedure, 38-hour duration between ovulation triggering and oocyte pick-up procedure
- Where
- 7 sites in Turkey (Türkiye)
- Volunteers
- 850 people
- Sponsor
- Koç University
IVF
Platelet Rich Plasma on Ovarian Reserve Parameters and Intra Cytoplasmic Sperm Injection Outcomes in Patients With Diminished Ovarian Reserve
The aim of this study is to evaluate the efficacy of intra ovarian injection of autologous platelet rich plasma on ovarian reserve parameters and ICSI outcomes in poor ovarian reserve.
- Trial name
- NCT06048666
- Testing
- Intra ovarian by platelet rich plasma
- Where
- Egypt
- Volunteers
- 56 people
- Sponsor
- Beni-Suef University
Infertility, Female, Depression
Educational and Supportive Care to Depressed Infertile Females
Infertility affects married adults, and In Vitro Fertilization (IVF) is an Assisted Reproductive Technology (ART) that can be treated. Women undergoing IVF are more likely to experience depression.
- Conditions
- Infertility, Female, Depression, IVF
- Trial name
- NCT06022640
- Testing
- Educational and supportive care
- Where
- Iraq
- Volunteers
- 150 people
- Sponsor
- Al-Rasheed University College
Infertility, IVF
The Importance of Embryo Transfer Day Progesterone Value in Natural Cycle Frozen Embryo Transfers and the Evaluation of the Effect of Rescue Therapy on Pregnancy Outcomes in Patients With Low Progesterone Levels
Thanks to recent advances in clinical practice and laboratory, embryo cryopreservation has become the first-line procedure in assisted reproductive technology.
- Conditions
- Infertility, IVF, Progesterone
- Trial name
- NCT05481684
- Testing
- Normal Progesterone group, Low Progesterone group
- Where
- 3 sites in Turkey (Türkiye)
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
IVF, Infertility
What To-be-discard Biomaterials From ART Cycles Can Tell us About the Treatment Cycle Outcome?
Various to-be-discard material from IVF treatment cycle will be collect and examined, aiming to identify potential reasons of successful outcome or cycle failure.
- Trial name
- NCT06021340
- Where
- Hong Kong
- Volunteers
- 50 people
- Sponsor
- Chinese University of Hong Kong
IVF, GnRH Antagonist
Live Birth Rate Between PPOS and GnRH Antagonist Protocol in Patients With Anticipated High Ovarian Response
Progestin can inhibit the pituitary LH surge during ovarian stimulation and various studies show progestin-primed ovarian stimulation (PPOS) is effective in blocking the LH surge in IVF.
- Conditions
- IVF, GnRH Antagonist, PPOS
- Trial name
- NCT04414761
- Testing
- Progesterone, GnRH Antagonist
- Where
- China
- Volunteers
- 784 people
- Sponsor
- ShangHai Ji Ai Genetics & IVF Institute
Myoma;Uterus, IVF
The Impact of Myomectomy on IVF Outcomes
In 2% to 3% infertility women, myoma is the only factor relevant to their infertility. However, the effects of intramural myoma on fertility are controversial.
- Conditions
- Myoma;Uterus, IVF, Surgery
- Trial name
- NCT05932082
- Testing
- myomectomy or not
- Volunteers
- 792 people
- Sponsor
- Peking Union Medical College Hospital
IVF
Effect of Tadalafil, Sildenafil and Pentoxyfylline on Frozen Embryo Transfer Outcomes
The aim of this study is to investigate the Effect of different vasodilators as Tadalafil, Sildenafil and pentoxyfylline in In vitro Fertilization.
- Trial name
- NCT05971667
- Testing
- tadalafil, Sildenafil, pentoxifylline
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Beni-Suef University
IVF
Dydrogesterone, Cetrorelix Acetate and Triptorelin in Intra Cytoplasmic Sperm Injection Outcomes
To compare the effects of Duphaston compared to GnRH agonist and antagonist on the prevention of premature LH surge and quality of retrieved oocytes and embryos in women undergoing intra-cytoplasmic sperm injection.
- Trial name
- NCT05972902
- Testing
- Dydrogesterone, Cetrorelix acetate, Triptorelin
- Where
- Egypt
- Volunteers
- 387 people
- Sponsor
- Beni-Suef University
IVF, PCOS
Single vs. Group CAPA-IVM Culture of Cumulus-oocyte Complexes
Oocyte in vitro maturation (IVM) is a minimal-stimulation ART with reduced hormone-related side effects and risks for the patients.
- Conditions
- IVF, PCOS, IVM
- Trial name
- NCT04562883
- Testing
- The way of Cumulus-oocyte complexes (COC) culture
- Where
- Vietnam
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Mỹ Đức Hospital
IVF
The Effect of Sildenafil Citrate on Frozen Embryo Transfer Cycles
to investigate the value of adding sildenafil citrate during endometrial preparation in patients undergoing frozen-thawed embryo transfer and its effect on endometrial thickness and pregnancy rates.
- Trial name
- NCT05951413
- Testing
- Sildenafil Citrate, estradiol
- Where
- Egypt
- Volunteers
- 110 people
- Sponsor
- Beni-Suef University
Infertility, IVF
Priority to Cryopreservation Strategy (PCS) in IVF-ICSI Cycles
This multicentre randomized controlled trial will be done to evaluate a new strategy in IVF-ICSI practice that gives that priority to freeze for the embryos and goes to fresh embryo transfer only if at least one set of same…
- Conditions
- Infertility, IVF, ICSI, Cryopreservation
- Trial name
- PCS (NCT03913208)
- Testing
- Priority to freeze, Fresh embryo transfer
- Where
- Egypt
- Volunteers
- 1,000 people
- Sponsor
- Tanta University
IVF
Effect of Reducing the Oxygen Concentration From 5% to 2% on ICSI Outcome
To assess the effect of reducing the oxygen concentration from 5% to 2% on Intracytoplasmic sperm injection (ICSI) outcome.
- Trial name
- NCT05924048
- Testing
- Reducing the Oxygen Concentration From 5% to 2%
- Where
- Egypt
- Volunteers
- 196 people, healthy volunteers welcome
- Sponsor
- International Islamic Center for Population Studies and Research
Infertility, IVF
Optimization of Frozen Embryo Transfers by Studying Progesterone on the Day of Transfer
The number of embryo transfers after freezing has increased over the last 10 years due to improvements in embryo freezing techniques and in particular the development of vitrification.
- Trial name
- OTEC (NCT04290520)
- Testing
- bioassay
- Where
- France
- Volunteers
- 115 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Infertility, In Vitro Fertilization
Virtual Reality for Acute Pain and Anxiety During Egg Retrieval for in Vitro Fertility Treatment
This study is a comparison between the current standard practice of performing a transvaginal oocyte retrieval (TVOR) with paracervical block (PCB) and a relatively recently developed technology of virtual reality that is added…
- Conditions
- Infertility, In Vitro Fertilization, IVF, ART
- Trial name
- NCT05438238
- Testing
- Oncomfort
- Where
- Belgium
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Universitair Ziekenhuis Brussel
Infertility, IVF
Micronized Progesterone vs Gonadotropin-releasing Hormone (GnRH) Antagonist in Freeze-all IVF Cycles.
To examine whether the number of euploid embryos following ovarian stimulation with micronized progesterone is equivalent as compared with the number of embryos after ovarian stimulation with the use of a GnRH antagonist in…
- Conditions
- Infertility, IVF, Preimplantation Diagnosis
- Trial name
- Prog_STIM (NCT04108039)
- Testing
- GnRh antagonist, Micronized progesterone
- Where
- Spain
- Volunteers
- 44 people
- Sponsor
- Fundacion Dexeus