Clinical trials: Ivf
Implantation Failure, Infertility
Endometrial Biopsy Prior to IVF in Those Patients With Prior Implantation Failure
This proposed research is a single center, prospective, single-blinded, randomized controlled trial, designed to evaluate IVF pregnancy outcomes following endometrial injury in 254 patients with implantation failure.
- Trial name
- EMBX/IVF (NCT01800513)
- Testing
- Endometrial Biopsy
- Where
- United States
- Volunteers
- 254 people
- Sponsor
- Shady Grove Fertility Reproductive Science Center
Infertility
Experience of Pain During Oocyte Retrieval- a Comparison Between Two Aspiration Needles
The purpose of the study is to compare the pain experience between the patients that have had their transvaginal oocytes retrieval with ultrasound guidance performed with reduced single lumen needle (Vitrolife Sweden AB…
- Trial name
- NCT00924885
- Testing
- Swemed Follicle Aspiration Set Reduced Single Lumen, Swemed Follicle Aspiration Set Single Lumen (1.4 mm)
- Where
- 4 sites in Sweden
- Volunteers
- 257 people
- Sponsor
- Vitrolife
Stress, Physiological, Infertility
Evaluation of the Impact of Stress on IVF Outcome
The purpose of this study is to determine if physiological measures of stress, measured by the non-invasive OTO device, are significantly correlated with IVF outcome.
- Conditions
- Stress, Physiological, Infertility, Stress, Psychological
- Trial name
- NCT05589571
- Where
- 43 sites in United States
- Volunteers
- 240 people
- Sponsor
- Inception Fertility Research Institute, LLC
Repeated IVF Failure, Female Infertility
Investigate the Efficacy of Using NMN to Improve Embryo Development Capacity.
The objective of this study is to investigate the efficacy of NMN supplementation in enhancing embryo developmental capacity and improving IVF success rates in patients experiencing IVF failures.
- Trial name
- NCT06629636
- Testing
- NMN capsule
- Where
- Japan
- Volunteers
- 60 people
- Sponsor
- Sunkaky Medical Cooperation
Female Infertility, Polycystic Ovary Syndrome
Vitamin D Supplementation and Improvement of PCOS Therapy and IVF Outcomes in Infertile Saudi Women
This randomized double-blinded-controlled clinical trial consists of two protocols as follow: protocol 1: evaluation of the therapeutic effects of Vitamin D3 supplement when given alone and in combination with an…
- Conditions
- Female Infertility, Polycystic Ovary Syndrome, Pathologic Processes, Vitamin D Deficiency
- Trial name
- NCT05106712
- Testing
- Vitamin D3, Clomiphene Citrate, Letrozole
- Volunteers
- 700 people
- Sponsor
- Umm Al-Qura University
Male Infertility
The Impact of Lifestyle on Sperm Telomere Length and Telomerase Activity in Men Undergoing IVF Treatments
This aim of this study is to determine the impact of lifestyle on telomere length and telomerase enzyme activity on sperm cells of men undergoing IVF treatments.
- Trial name
- NCT04158765
- Testing
- DNeasy Tissue Kit (QIAGEN Inc., Mississauga, Ontario, Canada) and PCR- based assay (TRAPeze Telomerase Detection Kit; Millipore, Billerica, MA).
- Where
- Israel
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Hillel Yaffe Medical Center
IVF
Effect of HCG on Endometrial Preparation in Frozen Embryo Transfer
Intramuscular injection of HCG to prepare endometrium for frozen embryo transfer
- Trial name
- NCT06577181
- Testing
- hCG + estradiol, Observation arm
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Assiut University
Infertility, Female
Immunophenotypage of RIF and RM Patients and Intrauterine Administration of PBMC
The purpose of this study is to identify a systemic immunological profile specific to patients with recurrent implantation failures (RIF) or miscarriages (RM) through blood immunophenotyping on the day of ovulation.
- Trial name
- NCT04753736
- Testing
- Intrauterine administration of hCG-activated peripheral blood mononuclear cells
- Where
- Canada
- Sponsor
- Fertilys
Each Patient is Both Case and Control, 1 Embryo Will be Biopsied and 1 Embryo is Not
Evaluation of the Impact of Embryo Biopsy on the Reproductive Potential of Embryos Undergoing In Vitro Fertilization (IVF)
To assess the impact of embryo biopsy on the reproductive potential of human embryos.
- Trial name
- NCT01219504
- Where
- 3 sites in United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Reproductive Medicine Associates of New Jersey
Infertility, Female, Reproductive Techniques, Assisted
SISTER: Sibling Oocyte Insemination With Frozen Sperm From Third Party Donors: Evaluation of Reproductive Techniques
The goal of this clinical trial is to learn whether two different methods of helping eggs and sperm join-intracytoplasmic sperm injection (ICSI) and conventional in vitro fertilization (IVF)-lead to better embryo development when…
- Conditions
- Infertility, Female, Reproductive Techniques, Assisted, Fertilization in Vitro
- Trial name
- SISTER (NCT07175571)
- Testing
- Intracytoplasmic Sperm Injection (ICSI), Conventional Insemination (IVF)
- Where
- United States
- Volunteers
- 95 people
- Sponsor
- Shady Grove Fertility Reproductive Science Center
Premature Ovarian Insufficiency
Finerenone for Premature Ovarian Insufficiency (POI)
This study is testing whether finerenone, a medicine currently used to protect the kidneys and heart, can help women with premature ovarian insufficiency (POI) grow ovarian follicles and produce eggs that can be collected for in…
- Trial name
- NCT07815509
- Testing
- Finerenone
- Where
- China
- Volunteers
- 46 people
- Sponsor
- The University of Hong Kong-Shenzhen Hospital
Infertility (IVF Patients), Ovarian Aging
Egg Quality Assessment
The goal of this observational study is to learn about egg physiology in humans. The main question it aims to answer is if there is an association between egg physiology and egg quality.
- Conditions
- Infertility (IVF Patients), Ovarian Aging, IVF
- Trial name
- NCT06609421
- Testing
- Informative Appointment
- Where
- United Kingdom
- Volunteers
- 100 people
- Sponsor
- Ovom Care GmbH
Infertility, Obesity
Metabolomic Embryo Profiles of Obese in Vitro Fertilization (IVF) Patients and Their Relationship With Polycystic Ovary Syndrome (PCO)
The present study aims to elucidate if there is a metabolomic profile alteration in the embryos of obese women in order to understand if the reduced implantation rate observed in these patients is directly related to this factor.
- Trial name
- NCT01448863
- Testing
- Culture medium metabolomic analysis
- Where
- 2 sites in Spain
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Instituto Valenciano de Infertilidad, IVI VALENCIA
Infertility, Female
Sildenafil and Outcome of IVF/ICSI Cycles
Adequate growth of the endometrium is crucial for implantation. Accordingly, the pregnancy success rate of patients with a thin endometrium is low.
- Trial name
- NCT03192709
- Testing
- Sildenafil vaginal suppositories
- Where
- Iran
- Volunteers
- 60 people
- Sponsor
- Royan Institute
Infertility Assisted Reproductive Technology, Infertility (IVF Patients)
Blastocyst AI Assisted Morphokinetics in ART
The goal of this observational study is to learn if embryo characteristics obtained via the recording of real-time embryo activity via 30-seconds video capture (e.g.: Embryo Morphokinetics) can correlate with known embryo outcome…
- Trial name
- AIM (NCT07611448)
- Where
- United States
- Volunteers
- 1,000 people
- Sponsor
- Viable Biosciences
Fertilization in Vitro, Infertility
The Impact of the Timing of Trigger on IVF Success
The aim of this study is to examine the length of ovarian stimulation with the timing of trigger in an IVF cycle and its potential to impact patient outcomes.
- Conditions
- Fertilization in Vitro, Infertility, Embryonic Development
- Trial name
- NCT02990949
- Testing
- Timing of trigger
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Colorado Center for Reproductive Medicine
Polycystic Ovary Syndrome
hMG or Recombinant FSH on OHSS Prevention in PCOS Patients Undergoing IVF
There have been some controversies regarding the use of preparations with LH activity in patients with polycystic ovary syndrome (PCOS) who have high endogenous LH activity.
- Trial name
- NCT01365936
- Testing
- HMG, rFSH
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Zekai Tahir Burak Women's Health Research and Education Hospital
OHSS
Cabergoline Versus Calcium Gluconate Infusion in the Prevention of Ovarian Hyperstimulation Syndrome
The aim of this study is to compare the efficacy of calcium gluconate infusion versus cabergoline in the prevention of ovarian hyperstimulation syndrome (OHSS) in patients pretreated with GnRH agonist long protocol who are at…
- Trial name
- NCT02875587
- Testing
- Cabergoline, Calcium gluconate
- Where
- 2 sites in Egypt
- Volunteers
- 170 people
- Sponsor
- Aljazeera Hospital
Infertility (IVF Patients)
The Effects of Carnitine Supplementation on Oocytes in Women Undergoing IVF Process
The goal of this clinical trial is to learn whether supplementation with L-carnitine improves outcomes in women undergoing in vitro fertilization (IVF).
- Trial name
- Carnitine Supp (NCT07783399)
- Testing
- L-Carnitine Group
- Where
- Serbia
- Volunteers
- 70 people
- Sponsor
- The Obstetrics and Gynaecology Clinic Narodni Front
Sterility, Placenta; Implantation
A Lifestyle Intervention to Improve in Vitro Fertilization Results
Embryo adhesion and placentation depend on tissue plasminogen activator (tPA)-mediated activation of brain-derived neurotrophic factor, vascular endothelial growth factor and other growth factors, formation of hemidesmosomes, and…
- Conditions
- Sterility, Placenta; Implantation, Risk Reduction Behavior, Lifestyle
- Trial name
- W+D (NCT02648555)
- Testing
- Daily walking, Dietary recommendations
- Where
- Brazil
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Hospital dos Servidores do Estado do Rio de Janeiro
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.