Clinical trials: Ivf
Diminished Ovarian Reserve
SMART Protocol vs Antagonist Protocol in IVF
This retrospective study aims to assess the effect of adding letrozole in patients who have previously undergone an IVF cycle with either an antagonist or short protocol, with patients who have undergone a second cycle of IVF…
- Trial name
- NCT05677828
- Where
- Canada
- Volunteers
- 426 people
- Sponsor
- Clinique Ovo
Infertility, AMH
Predictive Value of New AMH Test Method for Ovarian Response
In China, the incidence of infertility is about 15%, and patients need to use assisted reproductive technology (ART) to obtain pregnancy.
- Trial name
- NCT04639505
- Testing
- ELISA, Chemiluminescence
- Where
- China
- Volunteers
- 454 people
- Sponsor
- Reproductive & Genetic Hospital of CITIC-Xiangya
Infertility, Subfertility
The Microbiome in Subfertility and Assisted Reproductive Technologies (ART)
To assess the impact of the female genital microbiome on ART outcome.
- Trial name
- NCT03105453
- Testing
- 3 Sampling points
- Where
- Belgium
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Universitair Ziekenhuis Brussel
Communication, IVF
Uniform Communication by Midwives in Preparation for an IVF Treatment
Dutch-speaking women who are about to start an IVF treatment will be approached. If they are willing to participate in the study, they will receive an email with a link to an online questionnaire.
- Trial name
- UNCOVeR (NCT04420169)
- Testing
- Questionnaire
- Where
- Belgium
- Volunteers
- 105 people
- Sponsor
- University Hospital, Ghent
Assisted Reproduction
Effect of Trophectoderm Biopsy for Sex Selection on the Pregnancy and Miscarriage Rates of Women Undergoing IVF/ICSI
Records of women who had trophectoderm biopsy for sex selection over the last 3 years will be reviewed and its outcome will be compared to other records of women who had IVF/ICSI without embryo biopsy.
- Trial name
- NCT02412605
- Testing
- Trophectoderm embryo biopsy
- Where
- Egypt
- Volunteers
- 5,000 people
- Sponsor
- Cairo University
Infertility, Infertility (IVF Patients)
Endometrial Receptivity Prediction During in Vitro Fertilization Using Artificial Intelligence
The investigators plan to use artificial intelligence to analyse vaginal ultrasound images of the uterine lining (endometrium) taken during routine IVF treatment, which may predict implantation success during IVF treatment.
- Trial name
- NCT06717802
- Where
- Hungary
- Volunteers
- 1,500 people
- Sponsor
- Gottsegen National Cardiovascular Institute
Infertility
Outcomes of Couples After Failed PGD Management: A Single-Center Study at the Paris PGD Center (Antoine Béclère - Necker)
Preimplantation genetic testing (PGT) is a reproductive genetic technique aimed at preventing the transmission of severe genetic disorders.
- Trial name
- DECOPI (NCT07371312)
- Where
- France
- Volunteers
- 900 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Infertility
The Correlation Between Luteal Serum Progesterone and Live Birth Rate
The study design is an observational cohort study. Level of serum P4 will be collected on day OR+4 as well as on the day of embryo transfer (ET) either day OR+3 or OR+5.
- Trial name
- NCT05323513
- Where
- Denmark
- Volunteers
- 250 people
- Sponsor
- Peter Humaidan
Women Diagnosed With Cancer, Egg Donors
Oocyte Cryopreservation by Slow Freezing and Vitrification
This study seeks to evaluate whether the vitrification technique, as compared to the more traditional slow-cooling technique, leads to higher rates of successful thawing, fertilization, implantation and delivery.
- Conditions
- Women Diagnosed With Cancer, Egg Donors, Single Women, Failed Sperm Procurement in IVF
- Trial name
- NCT01223105
- Testing
- slow freeze, Vitrification
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Reproductive Medicine Associates of New Jersey
Reproductive Technology, Assisted, IVF Outcomes
Reproductive Outcomes After Intracytoplasmic Sperm Injection (ICSI) With Surgically Retrieved Sperm.
This research project explores how the source of sperm affects outcomes in assisted reproductive technologies (ART), focusing on children conceived through intracytoplasmic sperm injection (ICSI) with surgically retrieved sperm…
- Conditions
- Reproductive Technology, Assisted, IVF Outcomes, ICSI
- Trial name
- SRS-ICSI outc (NCT06951061)
- Testing
- IVF/ICSI
- Where
- Sweden
- Volunteers
- 200,000 people
- Sponsor
- Karolinska Institutet
Infertility
Efficacy of Pergoveris in Aged IVF Patients
To compare the efficacy between LH supplementation (Pergoveris) and non-LH supplementation (Follitropin alpha) in patients aged ≥ 35 years undergoing IVF treatment.
- Trial name
- NCT02244866
- Testing
- Pergoveris (FSH and LH), Follitropin alpha (FSH)
- Where
- Vietnam
- Volunteers
- 240 people
- Sponsor
- Vietnam National University
Fertilization in Vitro, Preservation of Supernumerary Embryos
Day 3 Embryo Cryopreservation: Metabolic and Viability Analysis
Embryo preservation through freezing plays a significant role in human assisted reproduction. It provides an opportunity for patients to have more than one attempt following an ovarian stimulation cycle, thereby decreasing the…
- Trial name
- NCT00608010
- Testing
- Vitrification, Slow freezing
- Where
- Turkey (Türkiye)
- Volunteers
- 186 people
- Sponsor
- V.K.V. American Hospital, Istanbul
Infertility
Efficacy and Safety of FE 999049 in Controlled Ovarian Stimulation in Japanese Women
To demonstrate non-inferiority of FE 999049 compared to FOLLISTIM with respect to number of oocytes retrieved in Japanese IVF/ICSI patients undergoing controlled ovarian stimulation.
- Trial name
- NCT03228680
- Testing
- Follitropin delta, Follitropin beta
- Where
- 17 sites in Japan
- Volunteers
- 373 people
- Sponsor
- Ferring Pharmaceuticals
Infertility, Female
A Randomised Trial Comparing the Ovarian Response of a Starting Dose of Either 10 μg or 15 μg Follitropin Delta (FE 999049) to a Starting Dose of Either 150 IU or 225 IU Follitropin Alfa (GONAL-F) in Conventional Regimens in China
This is a phase 3b clinical trial with follitropin delta (FE 999049) and Gonal-F. The trial is a randomised, controlled, assessor-blind, parallel groups, multicentre trial comparing the ovarian response of a starting dose of…
- Trial name
- COCO (NCT06173869)
- Testing
- FE 999049, GONAL-F
- Where
- 11 sites in China
- Volunteers
- 301 people
- Sponsor
- Ferring Pharmaceuticals
Infertility, Male Factor Infertility
A Randomized Clinical Trial Comparing Embryo Euploidy Rates Following Ultrashort Versus Standard Abstinence
This research is being done to determine if producing sperm after an ultrashort period of abstinence (1 hour of abstinence) will be effective in improving the rates of embryos with normal chromosomes (structures that carry…
- Trial name
- NCT07062237
- Testing
- Ultrashort abstinence, Standard abstinence
- Where
- United States
- Volunteers
- 187 people
- Sponsor
- UConn Health
Infertility, IVF
Micronized Progesterone vs Gonadotropin-releasing Hormone (GnRH) Antagonist in Freeze-all IVF Cycles.
To examine whether the number of euploid embryos following ovarian stimulation with micronized progesterone is equivalent as compared with the number of embryos after ovarian stimulation with the use of a GnRH antagonist in…
- Conditions
- Infertility, IVF, Preimplantation Diagnosis
- Trial name
- Prog_STIM (NCT04108039)
- Testing
- GnRh antagonist, Micronized progesterone
- Where
- Spain
- Volunteers
- 44 people
- Sponsor
- Fundacion Dexeus
Infertility Female
IVM for Patients With Low Ovarian Response. Does it Improve IVFoutcomes and Does it Improve the Following IVF Cycle?
Poor ovarian response (POR) is one of the major therapeutic challenges in in vitro fertilization. Several therapeutic approaches for POR have been explored; yet, a single effective strategy has not yet been established.
- Trial name
- NCT02498210
- Testing
- In Vitro Maturation Procedure
- Where
- Israel
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
IVF, Ovarian Cysts
GnRH Antagonist Pre-treatment in the Early Follicular Phase for Resolution of a Baseline Functional Ovarian Cyst
In this study we would like to examine the effect of GnRH antagonist administration at the beginning of the follicular phase in patient presenting with a simple ovarian cyst 25-50 mm.
- Trial name
- NCT04993924
- Testing
- Cetrorelix Acetate, Ganerelix Acetate
- Where
- Israel
- Volunteers
- 15 people
- Sponsor
- Assaf-Harofeh Medical Center
Infertility, IVF
Modified Rekovelle and Menopur Combination Protocol to Avoid Monitoring Before Day 10 of Stimulation
Follitropin delta (Rekovelle) algorithm established by Ferring provides personalized gonadotrophin doses based on each patient's weight and AMH.
- Trial name
- NCT05737979
- Testing
- Study chart review
- Where
- Canada
- Volunteers
- 772 people
- Sponsor
- Clinique Ovo
Cancer, Cancer in Pregnancy
ProspectiveFemaleAYA - Late Effects of Cancer Therapies on Gonadal Function, Fertility, Efficiency of Fertility Preservation Procedures and Pregnancy Outcomes
In the past two decades, the evidence-based knowledge on the prevalence and risk factors for gonads impairment, including infertility, following cancer and numerous cancer treatment regimen has significantly increased.
- Conditions
- Cancer, Cancer in Pregnancy, Infertility, In Vitro Fertilisation (IVF) Treatment
- Trial name
- FemFertilAYA (NCT07622420)
- Volunteers
- 3,000 people
- Sponsor
- Karolinska Institutet
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