Clinical trials: Jet Injection
Influenza, Human
Inactivated Influenza Via Jet Injection
The purpose of this study is to determine if the administration of flu vaccine using Needle-Free is equivalent to Needle and Syringe administration as measured by laboratory tests of immune response.
- Trial name
- IIJI (NCT02290691)
- Testing
- Influenza Vaccine
- Where
- 6 sites in United States
- Volunteers
- 985 people, healthy volunteers welcome
- Sponsor
- PharmaJet, Inc.
Jet Injection, Local Anasthesia
This Study Evaluate the Patient Response to Jet Injection, Pain and Satisfaction Compared to Conventional Method of Local Anasthesia Especially in Maxillary Teeth
Pain during administration of local anesthesia remains one of the major concerns in dental practice, often leading to anxiety and treatment avoidance.
- Trial name
- NCT07581249
- Testing
- Non aspirating dental syringe, The use of jet injection
- Where
- Iraq
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Baghdad
Influenza, Human
Jet Injection for Influenza
The purpose of this study is to determine if the administration of a seasonal flu vaccine using a PharmaJet's needle-free injection device (STRATIS) is equivalent to needle and syringe administration, as measured by laboratory…
- Trial name
- JIFI (NCT01688921)
- Testing
- AFLURIA vaccine (2012-2013 formulation), Needle-Syringe, Stratis needle-free injection device
- Where
- 3 sites in United States
- Volunteers
- 1,250 people, healthy volunteers welcome
- Sponsor
- PharmaJet, Inc.
Pain
Jet Injection of 1% Buffered Lidocaine Versus Topical ELA-Max for Anesthesia Prior to Intravenous (IV) Catheterization in Children
This trial is a comparison of the anesthetic effectiveness of J-Tip needle-free jet injection of 1% buffered lidocaine to the anesthetic effectiveness of topical 4% ELA-Max for peripheral intravenous catheter (PIV) insertion.
- Trial name
- NCT00444756
- Testing
- J-tip jet injection of 1% buffered lidocaine
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Norton Healthcare
Vaccine Reaction
Safety, Reactogenicity and Immunogenicity of a Venezuelan Equine Encephalitis DNA Vaccine Candidate Administered by Jet Injection
The goal of this clinical trial is to evaluate the safety and reactogenicity of a VEE DNA Vaccine candidate delivered by either intramuscular or intradermal jet injection.
- Trial name
- NCT06002503
- Testing
- Venezuelan Equine Encephalitis DNA Vaccine, PharmaJet Stratis Needle-free Injection System, PharmaJet Tropis Needle-free Injection System
- Where
- United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- PharmaJet, Inc.
Diabetes Mellitus, Type 1
Pharmacology of Insulin Injected With Jet-Injection
The purpose of this study is to compare the pharmacological profile of insulin administered with jet-injection with that of insulin injected with a conventional insulin pen.
- Trial name
- NCT00983775
- Testing
- jet injector (SQ pen/Novopen III)
- Where
- Netherlands
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Radboud University Medical Center
Dental Anxiety, Pain
Comparison of Five Anesthetic Delivery Systems for Palatal Infiltration
This study is a randomized clinical trial evaluating five different anesthetic delivery systems for palatal infiltration in adults undergoing maxillary molar extraction.
- Conditions
- Dental Anxiety, Pain, Dental, Palatal Anesthesia
- Trial name
- PAL-INJECT (NCT07184879)
- Testing
- Conventional Dental Syringe, Spring-Activated Syringe (PCJ, PAROJECT™), Needle-Free Jet Injector (NFI, Comfort-in™)
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Sercan Küçükkurt
Hantaan Virus Nephropathy, Puumala Virus Nephropathy
Safety/Immunogenicity Hantaan Virus DNA Vaccine and Puumala Virus DNA Vaccine, For Prevention of HFRS
A randomized 4 cohort study that is comparing the data collected during the earlier phase study and to determine if immunogenicity can be retained with a 1 mg dose of Hantaan DNA vaccine.
- Trial name
- NCT04333459
- Testing
- Hantaan DNA Vaccine/Puumala DNA Vaccine
- Where
- 2 sites in United States
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- U.S. Army Medical Research and Development Command
Lumbar Puncture, Topical Analgesia
Jet Injection of 1% Buffered Lidocaine Versus Topical EMLA for Local Anesthesia Before Lumbar Puncture in Children
The purpose of this study is to evaluate the effectiveness of a needle-free jet-injection system with 1% buffered lidocaine for local anesthesia for lumbar punctures compared to a topical anesthetic agent.
- Trial name
- JTIP (NCT01628874)
- Testing
- J-Tip, EMLA, Lidocaine
- Where
- United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Pain
J-Tip® Jet Injection of 1% Buffered Lidocaine or Saline Versus 4% Lidocaine Cream Before Venipuncture or IV Insertion
To measure and compare pain associated with venipuncture and peripheral intravenous catheter insertion among pediatric emergency department patients randomized to treatment with one of three different pain-reduction strategies…
- Trial name
- NCT00924963
- Testing
- J-Tip jet injector, Jet injection saline, lidocaine cream
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Influenza
Needle-free Jet Injection of Reduced-dose, Intradermal, Influenza Vaccine in >= 6 to < 24-month-old Children
This is a sequential phase I and II, controlled, double-blinded study to determine whether immune responses suggesting protection against influenza can safely be induced in young children by two reduced doses one month apart of…
- Trial name
- NCT00386542
- Testing
- Vaxigrip® trivalent inactivated influenza vaccine, Intradermal spacer on Biojector® 2000 jet injector
- Where
- Dominican Republic
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Pedro Moro
Anesthesia
Assessment of Needleless Jet Injection in Pain and Anxiety Management During Vital Pulpotomy of Primary Molars
To evaluate and compare the efficiency of needleless jet injection versus traditional inferior alveolar nerve block anesthesia in management of pain and anxiety during vital pulpotomy of lower second primary molars using…
- Trial name
- NCT06001710
- Testing
- Needleless jet injector
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Suez Canal University
HIV Infections
A Phase I Safety and Immunogenicity Trial of the Facilitated HIV-1 Gag-Pol DNA Vaccine (APL-400-047, Apollon, Inc.) Given Intramuscularly by Needle and Syringe or Biojector 2000 Needle-Free Jet Injection System in HIV-1 Uninfected Adult Volunteers
To evaluate the safety, tolerability and immunogenicity in humans of the APL-400-047 vaccine when administered intramuscularly by needle and syringe at 1 of 3 doses or by Biojector at the intermediate dose.
- Trial name
- NCT00001088
- Testing
- APL 400-047, Bupivacaine hydrochloride
- Where
- 4 sites in United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Healthy Adults
Safety Study of Seasonal Influenza Vaccine by Jet Injection
This research study involves testing of a device that can give injections (shots) without the use of a needle.
- Trial name
- NCT00987350
- Testing
- LectraJet, TIV by jet injection, Seasonal Trivalent Influenza Vaccine
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
HIV
Gardasil Immunogenicity With Needle-Free Injection
1. Compare rates of seroconversion and GMTs generated following a 3-dose series of vaccine in women given low doses of vaccine by the ID route with the NFI (Group III) to those women given standard doses by the IM route with a…
- Trial name
- GINI (NCT02363660)
- Testing
- GINI
- Where
- Thailand
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Thai Red Cross AIDS Research Centre
Diabetes Mellitus
Reliability of Insulin by Jet Injection
Using a specific jet injector for the administration of a rapid-acting insulin analogue has been shown to advance the absorption of insulin from the subcutaneous area into the bloodstream by 40-50%, when compared to conventional…
- Trial name
- NCT02272296
- Testing
- jet injector, Conventional pen (NovoPen IV)
- Where
- Netherlands
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Radboud University Medical Center
Dental Anesthesia
Clinical Evaluation and Comparison of Pain Acceptance of Different Types of Injection Systems
The goal of this randomized clinical trial is to compare two different injection methods in children. The main question it aims to answer is: Is the needle-free injection method more painless than the traditional dental method?…
- Trial name
- NCT06892873
- Testing
- Comfort-In, Traditional dental injection
- Where
- Turkey (Türkiye)
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Necmettin Erbakan University
Virus Diseases, Hepatitis B
Pilot Safety Study to Determine the Ability of the Protector Cap Jet Injector to Prevent Cross-Contamination
The primary purpose of this study is to determine the ability of the Protector Cap Jet Injector to prevent cross-contamination in the next injection sample.
- Trial name
- NCT00219453
- Testing
- Jet Injector with Protector Cap (HSI-500)
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- PATH
Anesthesia, Local
Pain Control of Needle-free Versus Needle Injected Local Anesthesia for Pulpotomy of Upper Primary Molars in Children
This is a study that will be conducted on 6 to 8 years old children to compare the needle-less jet injector with the conventional needle attached syringe in terms of efficiency in controlling pain of local anesthetic infiltration…
- Trial name
- NCT03917121
- Testing
- Jet injector, Needle attached dental syringe
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Cairo University
Pain, Local Infiltration
Pain Perception With a Comfort-ın Jet Injection and Conventional Dental Injection
The investigators aimed to compare the effectiveness of the Comfort-in system, which is a jet injection type, and infiltrative anesthesia with a traditional injector, and to measure the effect of children's anxiety on the…
- Conditions
- Pain, Local Infiltration, Anesthesia, Fear
- Trial name
- NCT04682080
- Testing
- Needle-free injection
- Where
- Turkey (Türkiye)
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Tokat Gaziosmanpasa University