Clinical trials: Jet Injection
Diabetes Mellitus
Pharmacology of Insulin Injected With Jet-injection in Diabetes
A previous study showed that absorption and glucose-lowering action of rapid-acting insulin analogues occurred twice as fast when these analogues were administered by jet injection technology rather than by conventional insulin…
- Trial name
- NCT01438632
- Testing
- jet injection device
- Where
- Netherlands
- Volunteers
- 24 people
- Sponsor
- Radboud University Medical Center
Keloid
Bleomycin Jet Injections in Keloids
This is a single center, double-blind (patient and investigator), randomized, placebo-controlled study with a split-lesion design, in which selected keloids will receive three consecutive treatments of a) bleomycin and b) placebo…
- Trial name
- NCT04582305
- Testing
- Bleomycin, Normal saline
- Where
- Netherlands
- Volunteers
- 14 people
- Sponsor
- Erasmus Medical Center
HIV Infections
A Phase I Safety and Immunogenicity Trial of the Facilitated HIV-1 Gag-Pol DNA Vaccine (APL-400-047, Apollon, Inc.) Given Intramuscularly by Needle and Syringe or Biojector 2000 Needle-Free Jet Injection System in HIV-1 Uninfected Adult Volunteers
To evaluate the safety, tolerability and immunogenicity in humans of the APL-400-047 vaccine when administered intramuscularly by needle and syringe at 1 of 3 doses or by Biojector at the intermediate dose.
- Trial name
- NCT00001088
- Testing
- APL 400-047, Bupivacaine hydrochloride
- Where
- 4 sites in United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Healthy Adults
Safety Study of Seasonal Influenza Vaccine by Jet Injection
This research study involves testing of a device that can give injections (shots) without the use of a needle.
- Trial name
- NCT00987350
- Testing
- LectraJet, TIV by jet injection, Seasonal Trivalent Influenza Vaccine
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
HIV
Gardasil Immunogenicity With Needle-Free Injection
1. Compare rates of seroconversion and GMTs generated following a 3-dose series of vaccine in women given low doses of vaccine by the ID route with the NFI (Group III) to those women given standard doses by the IM route with a…
- Trial name
- GINI (NCT02363660)
- Testing
- GINI
- Where
- Thailand
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Thai Red Cross AIDS Research Centre
Anesthesia
Needle-Free Lidocaine Injection vs Traditional Local Anesthesia in Infant Lumbar Puncture
We hypothesize that the J-Tip needle-free jet-injection system offers comparable pain control and greater provider satisfaction due to its less invasive nature compared to traditional needle infiltration of 1% lidocaine in…
- Trial name
- NCT06552351
- Testing
- Needle-Free Jet Injection of 1 % lidocaine, traditional needle infiltration of 1% lidocaine
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Oklahoma
Diabetes Mellitus
Reliability of Insulin by Jet Injection
Using a specific jet injector for the administration of a rapid-acting insulin analogue has been shown to advance the absorption of insulin from the subcutaneous area into the bloodstream by 40-50%, when compared to conventional…
- Trial name
- NCT02272296
- Testing
- jet injector, Conventional pen (NovoPen IV)
- Where
- Netherlands
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Radboud University Medical Center
Dental Anesthesia
Clinical Evaluation and Comparison of Pain Acceptance of Different Types of Injection Systems
The goal of this randomized clinical trial is to compare two different injection methods in children. The main question it aims to answer is: Is the needle-free injection method more painless than the traditional dental method?…
- Trial name
- NCT06892873
- Testing
- Comfort-In, Traditional dental injection
- Where
- Turkey (Türkiye)
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Necmettin Erbakan University
Virus Diseases, Hepatitis B
Pilot Safety Study to Determine the Ability of the Protector Cap Jet Injector to Prevent Cross-Contamination
The primary purpose of this study is to determine the ability of the Protector Cap Jet Injector to prevent cross-contamination in the next injection sample.
- Trial name
- NCT00219453
- Testing
- Jet Injector with Protector Cap (HSI-500)
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- PATH
Anesthesia, Local
Pain Control of Needle-free Versus Needle Injected Local Anesthesia for Pulpotomy of Upper Primary Molars in Children
This is a study that will be conducted on 6 to 8 years old children to compare the needle-less jet injector with the conventional needle attached syringe in terms of efficiency in controlling pain of local anesthetic infiltration…
- Trial name
- NCT03917121
- Testing
- Jet injector, Needle attached dental syringe
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Cairo University
Pain, Local Infiltration
Pain Perception With a Comfort-ın Jet Injection and Conventional Dental Injection
The investigators aimed to compare the effectiveness of the Comfort-in system, which is a jet injection type, and infiltrative anesthesia with a traditional injector, and to measure the effect of children's anxiety on the…
- Conditions
- Pain, Local Infiltration, Anesthesia, Fear
- Trial name
- NCT04682080
- Testing
- Needle-free injection
- Where
- Turkey (Türkiye)
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Tokat Gaziosmanpasa University
Healthy
Pharmacokinetic and Pharmacodynamic Profile of Insulin Lispro Using Needle-Free Jet Injection Technology
Needle-free jet injector provides an alternative for patients with diabetes treated by insulin. This study aimed at evaluating pharmacokinetics and pharmacodynamics (PK-PD) profiles of lispro administered by jet injector and…
- Trial name
- NCT02443714
- Testing
- Needle-free jet injection with insulin lispro, Conventional pen injection with insulin lispro
- Where
- China
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Chongqing Medical University
Male Infertility
The Acceptance, Safety, and Efficacy of MadaJet Versus Needle Injection for Sperm Retrieval in Patients With Azoospermia
To compare the acceptance, safety, and efficacy of needle-free jet anaesthetic technique (MadaJet) versus needle injection for sperm retrieval in patients with azoospermia.
- Trial name
- NCT03181243
- Testing
- Madajet, Needle injection
- Where
- Vietnam
- Volunteers
- 60 people
- Sponsor
- Vietnam National University
Influenza Prophylaxis
Clinical Trial Assessing the Immunologic Response to a Influenza Vaccine Delivered Using an Jet Injection Device or a Needle Syringe
The primary objective of this study was to evaluate if administration of a seasonal flu vaccine using a jet injector device is comparable to traditional needle and syringe delivery for eliciting an immune response.
- Trial name
- NCT01644149
- Testing
- Stratis Jet Injector, Needle and Syringe, 2011-2012 Fluzone trivalent inactivated influenza vaccine
- Where
- United States
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- PharmaJet, Inc.
Diabetes Mellitus, Type 2
Evaluation of Efficacy and Safety of Insulin Glargine Injected by Needle-free Jet Syringe
Using CGMS to compare the blood sugar improvement and patient sensibility of insulin glargine injected with needle-free jet injector and conventional insulin pen
- Trial name
- NCT04093284
- Testing
- The needle-free jet injector
- Volunteers
- 60 people
- Sponsor
- Nanjing First Hospital, Nanjing Medical University
Type 2 Diabetes
Comparing the Effects of Insulin Glargine on Blood Glucose Between Needle-free Jet Injection and Insulin Pen
To comparing the blood sugar improvement and patient sensibility of insulin glargine injected with needle-free jet injector and conventional insulin pen
- Trial name
- NCT04074603
- Testing
- The needle-free jet injector, Conventional insulin pen
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Jian-hua Ma
Pain
The Use of Jet Injection Lidocaine for Blood Draws in Young Children
This study looks at the use of Jet Injection Lidocaine (J tip) for pain during blood draws in children ages 6 and younger. The investigators will use video observation of patients to asses their pain during lab draws using either…
- Trial name
- NCT01890642
- Testing
- J tip, Pain Ease Spray, 1% buffered lidocaine
- Where
- United States
- Volunteers
- 205 people, healthy volunteers welcome
- Sponsor
- Medical College of Wisconsin