Clinical trials: Joint
Temporomandibular Disorders (TMD), Muscle Pain
Autologous Exosomes From Platelet-rich Plasma as a Modern Tool of Regenerative Dentistry
The aim of the research is the laboratory assessment of the content as well as the regenerative and anti-inflammatory potential of autologous exosomes (EXO) from platelet-rich plasma (PRP), as well as their comparison with other…
- Conditions
- Temporomandibular Disorders (TMD), Muscle Pain, TMJ Pain
- Trial name
- NCT07511959
- Testing
- Laboratory analysis of the content and biological activity of PRP, PRF, and exosomes obtained from blood samples
- Where
- Poland
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Wroclaw Medical University
Chronic Pain, Temporomandibular Joint Disorders
Brain Connectivity Patterns in Chronic Temporomandibular Joint Disorders
This study addresses the timely problem of painful temporomandibular disorders (TMD), the most common cause of orofacial pain second only to tooth pain.
- Conditions
- Chronic Pain, Temporomandibular Joint Disorders, Temporomandibular Joint Pain
- Trial name
- NCT05068908
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Sleep Bruxism, Sleep Disorder
Relationship Between Selected Parameters and Bruxism
Bruxism is a common phenomenon. It is estimated that its prevalence in the adult population is 8-31%. Bruxism occurring during sleep is the activity of the masticatory muscles that appear during sleep, which can be rhythmic or…
- Conditions
- Sleep Bruxism, Sleep Disorder, Psychosomatic Disorder, Pain
- Trial name
- WMU1/2019 (NCT04214561)
- Testing
- Polysomnography
- Where
- Poland
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Wroclaw Medical University
Temporomandibular Disorder (TMD)
JIT: Effect of Pain on DT in TMD
Individuals with chronic temporomandibular disorder (TMD) pain are at increased risk for alcohol-related consequences compared to those without pain, and growing evidence suggests pain is a potent motivator for alcohol use in…
- Trial name
- TMD (NCT06659991)
- Testing
- alcohol condition, control condition
- Where
- United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Temporomandibular Disorders (TMD)
Aerobic Physical Activity and Orofacial Myofascial Pain
Orofacial myofascial pain, most commonly represented by Temporomandibular Disorders (TMD) a significant public health, affecting approximately 12% to 14% of the general population.
- Trial name
- AERODOF (NCT07526688)
- Testing
- Temporal Summation of Pain and Questionnaire
- Where
- France
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University Hospital, Brest
Temporomandibular Dysfunction (TMD)
Cervical Proprioception, Masticatory Pain Threshold and Craniovertebral Angle in TMD
Temporomandibular disorder (TMD) is a group of conditions involving the masticatory muscles, temporomandibular joint (TMJ), and associated structures of the head, neck, and cervical region.
- Trial name
- NCT07681570
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Ankara Yildirim Beyazıt University
Thoracolumbar Spine Fracture, Facet Joint Degeneration
Degenerative Changes After Treatment of Thoracolumbar Junction Fractures
This observational study will evaluate how degenerative changes in the facet joints and intervertebral discs develop over time after treatment of AOSpine type A2, A3, and A4 fractures of the thoracolumbar junction.
- Conditions
- Thoracolumbar Spine Fracture, Facet Joint Degeneration, Intervertebral Disc Degeneration
- Trial name
- NCT07672184
- Where
- Russia
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Sklifosovsky Institute of Emergency Care
Temporomandibular Disorder (TMD), Bruxism
Temporomandibular Disorders and Bruxism in Elite Basketball Referees
This study aims to determine the frequency of temporomandibular disorders (TMD) and bruxism in elite basketball referees and to compare the findings with healthy controls.
- Trial name
- NCT07662486
- Where
- Turkey (Türkiye)
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Istanbul Physical Medicine Rehabilitation Training and Research Hospital
ADHD, Benign Joint Hypermobility Syndrome
Evaluation of Benign Joint Hypermobility and Serum Prolidase Levels in Children Diagnosed With Attention-Deficit/Hyperactivity Disorder (ADHD) Compared to Healthy Controls
This cross-sectional observational study investigates the clinical and biochemical relationship between Attention-Deficit/Hyperactivity Disorder (ADHD) and Benign Joint Hypermobility Syndrome (BJHS) in pediatric patients.
- Conditions
- ADHD, Benign Joint Hypermobility Syndrome, ADHD - Attention Deficit Disorder With Hyperactivity, ADHD - Combined Type
- Trial name
- NCT07663383
- Where
- Turkey (Türkiye)
- Volunteers
- 171 people, healthy volunteers welcome
- Sponsor
- Antalya Training and Research Hospital
Malocclusion, Temporomandibular Disorder
Postural Assessment in Patients With Malocclusions
This observational cross-sectional study aims to investigate the association between skeletal malocclusions and body posture using three-dimensional postural analysis.
- Conditions
- Malocclusion, Temporomandibular Disorder, Postural; Defect
- Trial name
- NCT07664059
- Testing
- Lateral teleradiography, Temporomandibular assessment with Helkimo Index, Three-dimensional postural assessment
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Andrea Scribante
Degenerative Joint Disease, Control Subjects
MRI of the TMJ in Patients With DJD
This observational research is comparative in design, that is assessing the change in qMRI measures in degenerative changes of the TMJ in patients diagnosed with DJD.
- Trial name
- NCT07008690
- Testing
- MRI, Magnetic Resonance Imaging
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Healthy, Temporomandibular Joint Disorders
ChAracterization of Normal and Pathological moRphological Variations of the TEMporomandibular Joint by Real-time magnetIc reSonance Imaging
The Real Time MRI Rapid Flash sequence is particularly interesting for the study of moving organs and joints. This sequence will make it possible to characterize normal and pathological temporomandibular joint movements by MRI.
- Trial name
- ARTEMIS (NCT06070558)
- Testing
- MRI with Real Time MRI Rapid Flash sequence
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Central Hospital, Nancy, France
Arthritis, Unstable Radial Head
Aptis PRUJ Prosthesis for the Treatment of Patients With Proximal Radial Ulna Joint Disorders.
A Prospective, Multi-Center, Single-Arm Clinical Trial of the safety and effectiveness of the Aptis PRUJ prosthesis for the treatment of patients with proximal radial ulna joint disorders
- Conditions
- Arthritis, Unstable Radial Head, Proximal Radioulnar Joint Instability, Decreased Motion at the Proximal Radioulnar Joint and/or the Radio-humeral Joint
- Trial name
- NCT05796908
- Testing
- Aptis PRUJ Prosthesis
- Where
- 7 sites in United States
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Aptis Medical
Lower Extremity Muscles Biomechanical Properties and Joint Range of Motion in Swimmers
Comparison of Lower Extremity Parameters in Monofin and Bi-fin Swimmers.
The purpose of this study is to compare the leg muscle features and joint movements of swimmers who use a single large fin (monofin) versus those who use two fins (bi-fins).
- Trial name
- NCT07621913
- Testing
- Measuring of the biomechanical properties of muscles with MyotonPro, Measurement of the length of the lower extremity with a tape measure., Measuring the range of motion of the lower extremity joints with a digital goniometer
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Istanbul Gelisim University
Psoriatic Arthritis, Psoriasis
Psorcast Mobile Study
The purpose of this study is to understand variation in the symptoms of psoriasis and psoriatic arthritis using simple, scalable smartphone-based measurements.
- Conditions
- Psoriatic Arthritis, Psoriasis, Psoriatic Conditions, Dermatologic Disease
- Trial name
- NCT05621369
- Testing
- Participant self-assessment surveys, Psoriasis Draw, Psoriasis Area Photo
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Sage Bionetworks
Ligament; Laxity
Evaluation of Anterior Tibial Translation of the Knee in Healthy Women, at Two Times of the Menstrual Cycle, on Hormonal Contraceptives or Not (FLEX)
Women's participation in sports at all levels has been increasing in recent decades. Many individual and team sports are at risk of anterior cruciate ligament (ACL) injury.
- Trial name
- FLEX (NCT05177549)
- Testing
- Bilateral knee examination with Lachmeter®
- Where
- France
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Nice
Joint Discomfort, Musculoskeletal Pain
A Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Effects of resO™ Bone and Joint Support Postbiotic on Physical Function, Pain Interference, and Mobility in Adults With Joint Discomfort
This randomized, double-blind, placebo-controlled study evaluates the effects of resO™ Bone and Joint Support Postbiotic on physical function, pain interference, mobility, and recovery in adults aged 18-75 years experiencing…
- Conditions
- Joint Discomfort, Musculoskeletal Pain, Mobility Limitation
- Trial name
- RESO101 (NCT07602426)
- Testing
- Supplement
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Able Biolabs, LLC
Periprosthetic Joint Infection
Study to Evaluate the REMEDY SPECTRUM GV IM Spacer Nail in the Treatment of Ankle-Related Infections
This study is being conducted to evaluate the safety and effectiveness of the REMEDY SPECTRUM IM Spacer Nail in the treatment of ankle-related infections.
- Trial name
- NCT06428448
- Testing
- REMEDY Spectrum IM Spacer Nail
- Where
- 3 sites in United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- OsteoRemedies, LLC
Autism Spectrum Disorder (ASD), Joint Attention
Joint Attention Processing in Social Threat Scenarios
This study set up two experiments using the free viewing video paradigm. By setting up social threat scenarios induced by humans (Experiment 1) and non social threat scenarios induced by objects (Experiment 2), combined with eye…
- Trial name
- NCT07582757
- Where
- China
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- University of Electronic Science and Technology of China
Autism Spectrum Disorder (ASD), Joint Attention Impairment
Social Attention in ASD and TD Children
To examine whether the spatiotemporal organization of gaze strategies differs between children with autism spectrum disorder (ASD) and typically developing (TD) children during a staged joint attention interaction, and to…
- Trial name
- NCT07583615
- Where
- China
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- University of Electronic Science and Technology of China