Clinical trials: Joint Diseases
Osteoarthritis, Hip
Evaluation of Functional Rehabilitation in Patients Undergoing Physiotherapy After Total Hip Arthroplasty
This study aims to objectively evaluate the implications of physiotherapeutic rehabilitation in the Assistance Protocol of Total Hip Arthroplasty (THA), by assessing the motor performance and testing the quality of life of…
- Trial name
- Artrhosis (NCT01491048)
- Testing
- THA Physiotherapy, No physiotherapy after THA
- Where
- Brazil
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Hospital de Clinicas de Porto Alegre
Femoracetabular Impingement
Muscular Morphological Ultrasound Epidemiological Study in Dance Professionals
This research will determine the presence of groin pain in professional dancers, through a specific questionnaire on the hip joint.
- Trial name
- DancersMUS (NCT05654168)
- Testing
- Imaging
- Where
- Spain
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Universidad de Murcia
Arthritis, Rheumatoid, Syndrome, Metabolic
An Exploratory Clinical Study on Autophagy During Fasting
Autophagy is considered one of the key molecular mechanisms for the broad preventive and therapeutic effects of periodic fasting.
- Conditions
- Arthritis, Rheumatoid, Syndrome, Metabolic, Healthy
- Trial name
- NCT04739852
- Testing
- Fasting
- Where
- Germany
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
TMJ Disorder
Correlation Between Types of Lateral Pterygoid Muscle Attachment and Internal Derangement of the Temporomandibular Joint
the study aimed to evaluate the clinical and MRI finding of TMJ AND LPM with predication of the risk factors. Study design: this retrospective study included 1365 joints in 800 patients diagnosed as TMJ internal derangement and…
- Trial name
- LPM & TMJ (NCT04951908)
- Testing
- MRI
- Where
- Egypt
- Volunteers
- 900 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Facet Joint Pain; Low Back Pain, Facet Joints; Degeneration ; Deep Learning ;Artificial Intelligence
Quantitative Assessment of Lumbar Facet Joint Degeneration, A Retrospective Study.
Observational study The purpose of this observational study was to understand the quantitative assessment of the degree of degeneration of lumbar facet joints, and to improve the Weishaupt grading system by using gray-scale curve…
- Conditions
- Facet Joint Pain; Low Back Pain, Facet Joints; Degeneration ; Deep Learning ;Artificial Intelligence, Facet Joint Disease
- Trial name
- NCT06786611
- Testing
- MRI
- Where
- China
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Shanghai Changzheng Hospital
Pulmonary Arterial Hypertension, HIV Infection
Auto-immunity and Pulmonary Arterial Hypertension
The investigators have recently evidenced the presence of antibodies to endothelial cells and fibroblasts in patients with idiopathic or SSc-associated PAH.
- Conditions
- Pulmonary Arterial Hypertension, HIV Infection, Congenital Heart Defect, Systemic Sclerosis
- Trial name
- Auto-HTAP (NCT01208792)
- Testing
- skin biopsy, Blood Sample
- Where
- 3 sites in France
- Volunteers
- 629 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Hip Osteoarthritis
RSA - ACTIS Hip Stem
The principal objective of this study is to compare mean 2-year subsidence of the ACTIS femoral stem using model-based RSA against published migration patterns for hip stems of a similar design.
- Trial name
- NCT04879732
- Testing
- ACTIS
- Where
- 3 sites in Canada
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Canadian Radiostereometric Analysis Network
Rheumatoid Arthritis
A Clinical Trial of Safety and Tolerance of TQH3821 Tablets in Adult Healthy Subjects
This study was a randomized, double-blind, placebo-controlled phase I clinical trial of TQH3821 in adult healthy subjects, which plans to recruit 72 healthy subjects.
- Trial name
- NCT05380934
- Testing
- TQH3821 tablets, Methotrexate tablets
- Where
- China
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
Rheumatoid Arthritis
A Study of Single and Multiple Oral Doses of TollB-001
The primary objective is to evaluate the safety and tolerability of TollB-001 following the administration of single or multiple oral doses in healthy adult subjects
- Trial name
- NCT06103773
- Testing
- TollB-001 tablets
- Where
- China
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Toll Biotech Co. Ltd. (Beijing)
Giant Cell Arteritis (GCA), Polymyalgia Rheumatica (PMR)
AYLo - AutoimmunitY and Loss of y
The AYLo study (AutoimmunitY and Loss of y - Investigating the Role of Hematopoietic Mutations and Mosaic Mutation in the Y Chromosome in Autoimmune Rheumatologic Diseases) aims to systematically investigate hematopoietic…
- Conditions
- Giant Cell Arteritis (GCA), Polymyalgia Rheumatica (PMR), ANCA Associated Vasculitis (AAV), Idiopathic Inflammatory Myopathies
- Trial name
- AYLo (NCT06696027)
- Testing
- Single nucleotide polymorphisms (SNP), 3'mRNA sequencing, Enzyme-linked immunosorbent assay (ELISA) and Legendplex Array
- Where
- Germany
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- University of Bonn
Knee Osteoarthritis
Knee Osteoarthritis Care: A Quality Improvement Intervention in General Practice
The aim of this study is to improve the referral rates to physiotherapy of patients with knee osteoarthritis. The intervention consists of one academic detailing visit directed to general practitioners (GPs)
- Trial name
- NCT03106142
- Testing
- Academic detailing visit arm
- Where
- Belgium
- Volunteers
- 177 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Joint Pain
Effectiveness of Cucumber Extract on Joint Pain
Joint pain is reported by about 1/3 of U.S. adults, and increases with age reaching 50% prevalence among the elderly [1]. Joint pain is associated with substantial activity limitation, work disability, sleep disturbance, negative…
- Trial name
- NCT06246383
- Testing
- Q Actin
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Jacksonville University
Shoulder Pain
The Effect of Acupressure on Shoulder Pain and Breastfeeding Self-efficacy
In this study, for the first time in our country, acupressure will be examined on post-cesarean shoulder pain and breastfeeding self-efficacy by using a combination of shoulder (GB21), hand (LI4) and leg (ST36) points and…
- Trial name
- NCT05729854
- Testing
- acupressure ( traditional and complementary medicine)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Agri Ibrahim Cecen University
Frozen Shoulder, Impairment Glucose Tolerance
Prevalence of Impaired Glucose Tolerance (IGT) in Patients With Frozen Shoulder
Idiopathic Adhesive Capsulitis, Frozen Shoulder is a condition in which there is a limitation and significant pain at the shoulder and it is increases with shoulder movements. The causes are not clear.
- Trial name
- NCT00926094
- Where
- Israel
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Knee Osteoarthritis (Kellgren-Lawrence Grade 1-3), Knee Osteoarthritis
Comparison of Leucocyte-rich PRP and Leucocyte-poor PRP in Treating Mild to Moderate Knee Osteoarthritis
The purpose of this study is to show that there is no difference in patient clinical scores when patients with knee pain are treated with joint application of high dose white blood cell PRP (platelet-rich plasma) and low dose…
- Conditions
- Knee Osteoarthritis (Kellgren-Lawrence Grade 1-3), Knee Osteoarthritis, PRP, Platelet-rich Plasma (PRP)
- Trial name
- NCT07857954
- Testing
- Intra-articular platelet-rich plasma
- Where
- Croatia
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- St. Catherine Specialty Hospital
Knee Osteoarthritis
Electromyographic Biofeedback on Performance of Vastus Medialis Oblique Muscle in Knee Osteoarthritis
This study intends to determine the Effects of Electromyographic biofeedback on performance of vastus medialis oblique muscle in knee osteoarthritis.
- Trial name
- NCT04194853
- Testing
- Electromyographic Biofeedback, Quadriceps Isometric exercises
- Where
- Pakistan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Sacroiliac Disorder
Muscle Energy Technique on Sacroiliac Dysfunction
Sacroiliac pain is a huge problem in women during pregnancy and postpartum period. Muscle energy technique has potential effect in decreasing the pain and disability
- Trial name
- NCT05088837
- Testing
- muscle energy technique, ice and heat packs
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Cairo University
Surgery, Arthroscopic, Analgesia
Preoperative Fluoroscopy Guided Hip Articular Branch Blocks and Analgesic Outcomes Following Hip Arthroscopy
Arthroscopic hip surgeries are increasingly being performed as both diagnostic and therapeutic interventions. These procedures are considerably painful, thus requiring the proper pain management techniques in order to provide…
- Conditions
- Surgery, Arthroscopic, Analgesia, Pain, Acute
- Trial name
- NCT04538105
- Testing
- Control, Articular Branch Block (ABB)
- Volunteers
- healthy volunteers welcome
- Sponsor
- Rush University Medical Center
Arthritis
Pharmacokinetics and Metabolism Study of Radiolabeled BMS-986142 in Healthy Male Subjects
This is an open-label, single-dose, study in healthy males. The primary objective is to assess the pharmacokinetics (PK), metabolism, and routes of elimination of a single oral dose of radiolabeled BMS-986142 in healthy male…
- Trial name
- NCT02880670
- Testing
- BMS-986142
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Bristol-Myers Squibb
Osteoarthritis, Knee, Meniscus; Degeneration
High Tibial Osteotomy With/Without Arthroscopy.
This study will compare Hight Tibial Osteotomy with or without arthroscopically repair intra-articular knee lesions in patients with early stages of Osteoarthritis.The purpose of this study is evaluate if addition of arthroscopy…
- Trial name
- NCT05128851
- Testing
- HTO, Arthroscopy treatment, Micro fractures
- Where
- Poland
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Centre of Postgraduate Medical Education
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