Clinical trials: Joint Replacement
Total Elbow Replacement
Prognostic Factors Associated With Failure of Total Elbow Replacement
This observational study aims to evaluate potential prognostic factors for TER failure . The National Joint Registry (NJR) currently contains the largest elbow registry dataset in the world, which has been shown to have high…
- Trial name
- NCT06760585
- Where
- United Kingdom
- Volunteers
- 4,073 people
- Sponsor
- University of Manchester
Total Joint Replacement Surgery, Postoperative Nausea and Vomiting
Aromatherapy in Reducing PONV for Total Joint Replacement Patients
This study investigates the effectiveness of aromatherapy in reducing postoperative nausea and vomiting (PONV) among patients undergoing total joint replacement surgery, as these complications can lead to patient discomfort and…
- Trial name
- RCT PONV (NCT07281885)
- Testing
- Aromatherapy patches, Control (Standard treatment)
- Where
- Hong Kong
- Volunteers
- 159 people
- Sponsor
- Hong Kong Buddhist Hospital
Knee Osteoarthritis
Effect of Physiotherapy After Total Knee Replacement
Physiotherapy plays an important part in rehabilitation after total knee arthroplasty. Even if this is a common practice, few studies have been performed on this issue.
- Trial name
- NCT00807716
- Testing
- walking skill group, usual physiotherapy care
- Where
- Norway
- Volunteers
- 57 people
- Sponsor
- University of Oslo
Osteoarthritis, Hip
Systemic Steroids for Peripheral Nerve Blocks
This study will investigate the ability of systemic dexamethasone to prolong the sensory block duration for lumbar plexus nerve blockade.
- Trial name
- NCT02464176
- Testing
- Dexamethasone, Bupivacaine, Epinephrine
- Where
- United States
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Osteoarthritis, Post-traumatic Arthritis
Postoperative Function Following Partial and Total Knee Replacement
The purpose of this study is to determine if patients with a fixed-bearing or mobile-bearing partial knee replacement perform functional activities differently than patients that have had total knee replacement or healthy…
- Trial name
- NCT00492219
- Testing
- Vanguard M fixed-bearing or Oxford mobile-bearing prostheses, Total Knee Replacement
- Where
- United States
- Volunteers
- 324 people, healthy volunteers welcome
- Sponsor
- New Lexington Clinic
Osteoarthritis
A Single Time-Point Study to Evaluate the ConforMIS iTotal® (CR) Knee Versus Off-the-Shelf
It has been noted that patients "dramatically overestimate their functional ability early after surgery." Despite use of assistive devices increasing and functional testing scores decreasing post-surgery, the patient reported…
- Trial name
- STEPS (NCT02251522)
- Testing
- ConforMIS Total Knee Replacement System, Off-the-Shelf Knee Replacement System
- Where
- 16 sites in United States, Germany
- Volunteers
- 873 people
- Sponsor
- Restor3D
Hip or Knee Replacement
'M'-Technique, Guided Imagery, or Standard of Care on Anxiety and Pain Pre- & Post-operatively in Elective Joint Replacement Patients
In the M-TIJRP protocol the investigators will utilize two Integrative Medicine modalities in a randomized, controlled study using either the 'M'-Technique® developed by Jane Buckle, PhD or Diane L.
- Trial name
- M•TIJRP (NCT01874379)
- Testing
- 'M'-Technique®, Guided Imagery, Standard of Care
- Where
- United States
- Volunteers
- 225 people
- Sponsor
- Saint Clare's Health System
Arthroplasty
The Effect of the Combined Use of Naloxone and Tramacet on Postoperative Analgesia in the Elderly
Ten patients 70 years and older having elective total hip/knee replacement surgery will be recruited to receive a continuous IV infusion of naloxone and oral tramacet for analgesia.
- Trial name
- NCT00665262
- Testing
- tramacet
- Where
- Canada
- Volunteers
- 10 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Frozen Shoulder, Adhesive Capsulitis
Effect of Hormone Replacement Therapy on Physiotherapy Outcomes in Postmenopausal Women With Frozen Shoulder
The purpose of this study is to compare the effects of a physiotherapy program on pain levels, shoulder range of motion, functional status, pain catastrophizing, perceived change, sleep quality, and quality of life in…
- Conditions
- Frozen Shoulder, Adhesive Capsulitis, Adhesive Capsulitis of the Shoulder, Hormone Replacement Therapy, Post-Menopausal
- Trial name
- NCT07736027
- Testing
- Standardized Physiotherapy Program
- Where
- Turkey (Türkiye)
- Volunteers
- 56 people
- Sponsor
- Istanbul University - Cerrahpasa
Osteoarthritis, Knee
All-Polyethylene Tibias in TKA: PS vs CS Implants
This is a randomized control trial where patients will be randomized to receive one of two types of total knee arthroplasty (TKA) all-polyethylene (AP) tibial components: cruciate retaining (CR) or posterior stabilized (PS).
- Trial name
- NCT03569670
- Testing
- Posterior stabilized all-polyethylene tibial component, Cruciate retaining all-polyethylene tibial component
- Where
- Canada
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Osteoarthritis
A Study to Determine the Performance of the Press Fit Condylar (P.F.C.) Sigma RP-F Knee System
The purpose of this study is to evaluate if the P.F.C. Sigma RPF knee accommodates functional stability with a post-operative passive range of motion of greater than 125° of flexion and to demonstrate that the range of motion…
- Trial name
- NCT00761410
- Testing
- P.F.C. Sigma RP-F Total Knee Replacement
- Where
- 8 sites in India, Japan and 5 more
- Volunteers
- 170 people
- Sponsor
- DePuy International
Osteoarthritis, Knee
Comparison of Surgical Time and Efficiency of Total Knee Arthroplasty
This study is designed to compare the surgical efficiency of TruMatch® Personalized Solutions surgical technique compared to conventional surgical technique.
- Trial name
- NCT01301950
- Testing
- Custom Patient Instrumentation, Conventional Instruments
- Where
- 3 sites in United States
- Volunteers
- 30 people
- Sponsor
- DePuy Orthopaedics
Osteoarthritis, Osteoarthritis (OA) of the Knee
Feasibility of Choose to Move Replacement Ready
Choose to Move (CTM) is a 3-month, choice-based health-promoting program for low active older adults being scaled-up across British Columbia (BC), Canada.
- Conditions
- Osteoarthritis, Osteoarthritis (OA) of the Knee, Osteoarthritis, Hip, Total Knee Arthroplasty; Total Hip Arthroplasty
- Trial name
- CTM-RR (NCT07069179)
- Testing
- Choose to Move Replacement Ready
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- University of British Columbia
Hip Osteoarthritis
The Ace Avanteon Study - A Randomized Controled Trial
The goal of this randomized controled trial is to compare if using of ancillary screws yields equal results as no use of ancillary screws in the ACE acetabulum cup of a total hip arthroplasty.
- Trial name
- NCT06499038
- Testing
- Total Hip Arthroplasty
- Where
- Norway
- Volunteers
- 60 people
- Sponsor
- Helse Møre og Romsdal HF
Prosthetic Joint Infection
Cost Of Failure Following Reimplantation After a 2-Stage Exchange Strategy For Hip Or Knee Prosthetic Joint Infection
This study concerns patients having had an infection on their prosthesis (hip, knee,..) and for whom a 2-step exchange of prosthesis has been done.
- Trial name
- NCT03612076
- Testing
- Global cost of management of PJI
- Where
- France
- Volunteers
- 115 people
- Sponsor
- Hospices Civils de Lyon
Joint Diseases, Joint Inflammation
Evaluating Replacement of Standard-of-care Low Dose Computer Tomography (CT) Scans With Radiation-free Bone Imaging by Deep-learning Augmented Zero Echo Time (DL-ZTE) Magnetic Resonance Tomography (MRT)
The goal of this clinical trial is to determine how effectively bone structures of the human skeleton can be visualized using Deep Learning (DL) augmented Magnetic Resonance Imaging (MRI) in individuals with inflammatory and…
- Trial name
- DLZTECT (NCT06579547)
- Testing
- Low Dose Computer Tomography
- Where
- Switzerland
- Volunteers
- 100 people
- Sponsor
- Roman Guggenberger
Knee Osteoarthritis
PARQVE Prior to Total Knee Replacement
Introduction: Elderly patients, the majority of the population submitted to total knee arthroplasty (TKA), have a lower capacity for adaptation to hospitalization and surgical stress.
- Trial name
- NCT04017858
- Testing
- Multiprofessional and educational Program prior to Total knee replacement TKA. (PARQVE TKA)., Patients will be submitted to total knee replacement.
- Where
- Brazil
- Volunteers
- 44 people
- Sponsor
- University of Sao Paulo General Hospital
Osteoarthritis, Knee
Prehab Intervention in Patients Awaiting Total Knee Arthroplasty (TKA)
The objectives of this study are to investigate the feasibility primarily and furthermore the effects of a four to eight-weeks program of a combined clinic- and home-based preoperative physical therapy (exercise training and…
- Trial name
- NCT05314985
- Testing
- Prehab intervention
- Where
- Switzerland
- Volunteers
- 20 people
- Sponsor
- Balgrist University Hospital
Osteoarthritis of the Knee
Structured Treatment of Osteoarthritis of the Knee With or Without Total Knee Replacement
The purpose of this study is to test whether surgical insertion of total knee replacement provides further improvement in quality of life, pain and function in addition to an algorithm for systematic non-surgical treatment…
- Trial name
- MEDIC (NCT01410409)
- Testing
- Neuromuscular training (NEMEX-TJR), Paracetamol, Burana
- Where
- 3 sites in Denmark
- Volunteers
- 100 people
- Sponsor
- Northern Orthopaedic Division, Denmark
Joint Replacement Surgery
The Effect of a Psychosensory Therapy
This is a prospective study looking at the impact of psychosensory therapy and how it can diminish pain and consumption of pain medications.
- Trial name
- NCT02765932
- Testing
- Dummy Movements, Psychosensory Therapy
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- NYU Langone Health