Clinical trials: Juvenile-Onset Diabetes
Type 1 Diabetes Mellitus, Insulin Pump
Evaluating an Insulin Pump for Time in Range (TIR) in Patients with Type 1 Diabetes
Diabetes mellitus is a metabolic disorder caused by genetic, environmental changes, mental health issues, immune disorders, and other factors.
- Conditions
- Type 1 Diabetes Mellitus, Insulin Pump, Time in Range
- Trial name
- NCT06741943
- Testing
- insulin pump (model: AR-B200A)
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Tao Yuan，MD
Type 1 Diabetes
Beta Cell Function in (Pre) Type 1 Diabetes
This study will establish criteria indicating short-term loss of beta cell mass and therefore accelerated progression towards type 1 diabetes.
- Trial name
- NCT00800085
- Testing
- glucose 20%
- Where
- 4 sites in Belgium
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Universitair Ziekenhuis Brussel
Type1 Diabetes Mellitus, Diabetes Mellitus, Type 1
MEtabolic and Renal Effects of AutoMAted Insulin Delivery Systems in Youth With Type 1 Diabetes Mellitus
In type 1 diabetes (T1DM), automated insulin delivery (AID) systems such as the hybrid closed loop artificial pancreas (HCL AP) combine the use of an insulin pump, continuous blood sugar monitor, and control algorithm to adjust…
- Conditions
- Type1 Diabetes Mellitus, Diabetes Mellitus, Type 1, Autoimmune Diabetes, Juvenile Diabetes
- Trial name
- MERMAID-T1D (NCT03945747)
- Testing
- Blood draw, Urine sample collection, DXA scan
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Colorado, Denver
Diabetes Mellitus Type 2, Diabetes Mellitus Type 1
SMARTCLOTH. Design, Implementation and Study of the Effectiveness and Usability of a Digital Tablecloth for Self-management of Diet in Diabetic Patients.
The objective of this clinical trial is to know the usability and efficacy of SMARTCLOTH for better control and adherence to the dietary patterns recommended to patients with diabetes, both the portion diet system (more common…
- Trial name
- NCT06623708
- Testing
- SMARTCLOTH
- Where
- 5 sites in Spain
- Volunteers
- 90 people
- Sponsor
- Maimónides Biomedical Research Institute of Córdoba
Diabetes Mellitus, Type 1
Counter-Regulatory Impairment and the Effect of Microvascular Insulin Transfer in Type 1 Diabetes Mellitus
The researchers plan to test the following hypothesis: A good level of glucose control in Type 1 Diabetes Mellitus (T1DM) is dependent on two levels of feedback from the body: 1.
- Trial name
- BPK003 (NCT00943787)
- Testing
- Hyperinsulinemic, euglycemic and hypoglycemic clamp
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- University of Virginia
Type 1 Diabetes
Efficacy and Safety of Sorafenib in New-Onset Type 1 Diabetes Mellitus
The purpose of this study is to investigate the therapeutic effect and safety of Sorafenib in T1DM patients.
- Trial name
- NCT06227221
- Testing
- Sorafenib
- Volunteers
- 10 people
- Sponsor
- Second Xiangya Hospital of Central South University
Virtual Reality
Virtual Reality and Children With Type 1 Diabetes
For children with type 1 diabetes (T1D), pain and needle phobia can cause postponing of changes in insulin pump infusion sets and continuous glucose monitors, and thus worsen glycemic control.
- Trial name
- NCT05883267
- Testing
- Virtual reality glasses, Vocal-guided affective imagery
- Where
- Israel
- Volunteers
- 40 people
- Sponsor
- Sheba Medical Center
Type1 Diabetes Mellitus
Evaluation of the Effectiveness of a Program of Emotional Intelligence in Adolescents With Type 1 Diabetes (INTEDI)
Type 1 Diabetes Mellitus is one of the main health problems of the pediatric population worldwide, being one of the most frequent chronic endocrinology diseases in childhood and adolescence.
- Trial name
- INTEDI (NCT03734367)
- Testing
- Emotional abilities training program
- Where
- Spain
- Volunteers
- 62 people
- Sponsor
- Universidad Loyola Andalucia
Diabetes, Diabetes Mellitus, Type 1
Evaluation of Accuracy of Continuous Glucose Monitoring (CGM) in Patients With End Stage Renal Disease (ESRD) on Intermittent Hemodialysis (iHD).
Recent advances in continuous glucose monitors (CGMs) and availability of commercial CGM products to patients with type 1 and type 2 diabetes has made the use of CGM more widespread.
- Conditions
- Diabetes, Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2
- Trial name
- NCT04094064
- Testing
- Continuous Glucose Monitor
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Virginia
Type 1 Diabetes
Study of Insulin Therapy Augmented by Real Time Sensor IN Type 1 Children and Adolescents (START-IN!)
Glycemic control in children and adolescent with type 1 diabetes remains inadequate, exposing them to the risk of vascular complications in adulthood.
- Trial name
- START-IN (NCT00949221)
- Testing
- monitor Paradigm 754 VEO, MINILINK Real Time, Medtronic, CE
- Where
- France
- Volunteers
- 150 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Type 1 Diabetes Mellitus
Ovarian Ageing in Type 1 Diabetes Mellitus
In healthy women, early menopause is an event that is associated with the exacerbation of several risk factors of cardiovascular and skeletal disease.
- Trial name
- OVADIA (NCT01665716)
- Where
- Netherlands
- Volunteers
- 290 people, healthy volunteers welcome
- Sponsor
- UMC Utrecht
Erectile Dysfunction
Evaluation of Efficacy and Safety of Vardenafil in Patients With Erectile Dysfunction and Type 1 Diabetes
Asses efficacy of Vardenafil in patients with type 1 diabetes and erectile dysfunction
- Trial name
- NCT00660998
- Testing
- Levitra (Vardenafil, BAY38-9456)
- Volunteers
- 318 people
- Sponsor
- Bayer
Type 1 Diabetes
A Learning Algorithm for MDI Individuals With Type 1 Diabetes to Adjust Recommendations for High Fat Meals and Exercise Management
McGill artificial pancreas lab has developed a learning algorithm using a reinforcement learning approach to adjust basal and bolus recommendations for high-fat meals and exercise management for individuals with type 1 diabetes…
- Trial name
- NCT05041621
- Testing
- Sensor augmented MDI therapy plus mobile application
- Where
- Canada
- Volunteers
- 15 people
- Sponsor
- McGill University
Diabetes Mellitus, Type 1
Effect of Basal-Bolus Closed-Loop Co-Administration of Insulin and Pramlintide on Improving the Glycemic Control in Type 1 Diabetes
The closed-loop delivery system is composed of an insulin pump, a continuous glucose sensor and a dosing algorithm that calculates the insulin dose to infuse based on sensor readings.
- Trial name
- NCT02814123
- Testing
- 24-hour inpatient intervention
- Where
- Canada
- Volunteers
- 28 people
- Sponsor
- McGill University
Diabetes Mellitus, Type 2
isCGM With Education and Feedback for Non-Insulin Dependent Type 2 Diabetes
Glycemic control is an important for adults with diabetes. Self-monitoring of glucose can help adults with type 2 diabetes (T2DM) meet their glucose targets.
- Trial name
- iCUDE (NCT05319496)
- Testing
- Intermittently scanned continuous glucose monitor (isCGM), Education and coaching
- Where
- Canada
- Volunteers
- 105 people
- Sponsor
- University of Alberta
Type 1 Diabetes Mellitus, Diabetic Ketoacidosis
Biomarkers of Acute Organ Injury in Pediatric Newly Diagnosed Type 1 Diabetes
Diabetic ketoacidosis (DKA) is a severe metabolic complication in children with newly diagnosed type 1 diabetes mellitus (T1DM) and may be associated with early injury of vital organs such as the kidneys and the heart.
- Trial name
- NCT07483879
- Testing
- Biomarker and Echocardiographic Assessment
- Where
- Greece
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Aristotle University Of Thessaloniki
Type 1 Diabetes, Type 2 Diabetes
Blood Glucose Response to Meals of Varying Glycemic Index in Youth With Type 1 & 2 Diabetes
Research to date suggests that the selection of lower glycemic index foods, that is, foods provoking a slower, more sustained blood sugar response, may result in improved glycemic control in youth with diabetes.
- Conditions
- Type 1 Diabetes, Type 2 Diabetes, Impaired Glucose Metabolism
- Trial name
- NCT00545727
- Testing
- Diet, Standard diet
- Volunteers
- 36 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Type 1 Diabetes Mellitus
Comparison of Insulins Aspart and Lispro in Insulin Pumps
The purpose of the study is to compare the glycemic control between insulins aspart and lispro 48 to 100 hours after pump infusion line change in subjects with type 1 using diabetes using an insulin pump.
- Trial name
- NCT00461331
- Testing
- Insulin Aspart, Insulin Lispro
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Tulane University Health Sciences Center
Type 1 Diabetes Mellitus
Omnipod 5 Implementation in Belgian Paediatric Diabetes Care
This study will evaluate the introduction and use of the Omnipod® 5 hybrid closed-loop insulin delivery system in children and adolescents with type 1 diabetes following its reimbursement in Belgium.
- Trial name
- O5-IMPACT (NCT07785037)
- Testing
- Tubeless Hybrid Closed-Loop Insulin Delivery System
- Volunteers
- 200 people
- Sponsor
- Queen Fabiola Children's University Hospital
Type 1 Diabetes Mellitus
Evaluation of a Simulation-Based Educational Tool for Personalized Feedback in Insulin Therapy Management
This study combines data collection and simulation-based education, and it will enroll up to 36 adults with T1DM who already have experience with insulin pump therapy and some experience with a continuous glucose monitor (CGM).
- Trial name
- NCT01767831
- Testing
- iBOLUSED
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- University of Virginia
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.