Clinical trials: Kidney; Disease, Acute
Chronic Kidney Diseases, Blood Pressure
Curcumin and Exercise in Chronic Kidney Disease
Chronic kidney disease (CKD) is associated with a pro-oxidative and pro-inflammatory state, and this is thought to contribute to a decrease in vascular function leading to greater cardiovascular disease (CVD) risk.
- Conditions
- Chronic Kidney Diseases, Blood Pressure, Hyperemia, Vasoconstriction
- Trial name
- NCT04132648
- Testing
- Curcumin
- Sponsor
- University of Iowa
Acute Heart Failure
VExUS in Patients With Acute Heart Failure
The importance of assessing venous congestion in heart failure patients is widely acknowledged, but its study is hampered by the lack of a practical evaluation tool.
- Trial name
- NCT06397404
- Testing
- Venous excess ultrasound score (VExUS) protocol
- Where
- Russia
- Volunteers
- 100 people
- Sponsor
- I.M. Sechenov First Moscow State Medical University
Chronic Kidney Disease
Usefulness of Neutrophil Gelatinase-associated Lipocalin(NGAL) to Confirm Acute Kidney Function Decrease of the Patients Who Had Non-cardiac Surgery
Although post-op renal function decrease is determined by serum creatinine, serum creatinine has disadvantages that it increases a long time after renal function decrease and it has various increasing time based on the level of…
- Trial name
- NCT02233010
- Testing
- The level of NGAL after pre op,post op 4hr, post op 12hr
- Volunteers
- 43 people
- Sponsor
- Inje University
Acute Kidney Injury
Renal Arterial Resistive Index for Differential Diagnosis of Acute Kidney Injury
early differential diagnosis of anticipated acute kidney injury via ultrasound renal resistive index calculation
- Trial name
- NCT05409690
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Ankara Diskapi Training and Research Hospital
Nephrectomy, Renal Cell Cancer
Contrast-enhanced Ultrasound and Super-resolution Imaging Predict Renal Function Outcome After Nephrectomy
The goal of this prospective cohort study is to evaluate the predictive value of Contrast-Enhanced Ultrasound (CEUS) and Super-Resolution Imaging (SRI) technologies regarding renal function outcomes in patients with renal cell…
- Conditions
- Nephrectomy, Renal Cell Cancer, AKI - Acute Kidney Injury
- Trial name
- NCT07294859
- Where
- China
- Volunteers
- 285 people
- Sponsor
- Jinling Hospital, China
Acute Kidney Injury, Liver Transplantation
Perioperative Evaluation of Terlipressin Infusion During Living Donor Liver Transplantation on Incidence of Acute Kidney
To study the impact of intra and post-operative Terlipressin infusion on the occurrence of acute kidney injury after LDLT To investigate perioperative Neutrophil Gelatinase Associated Lipocalin (NGAL) changes and study the effect…
- Conditions
- Acute Kidney Injury, Liver Transplantation, Terlipressin, NGAL
- Trial name
- Terli-NGAL (NCT02059460)
- Testing
- Terlipressin
- Where
- Egypt
- Volunteers
- 25 people
- Sponsor
- National Liver Institute, Egypt
Renal Failure, CVVHD
Analysis of Paediatric Treatments With multiFiltratePRO
This clinical study evaluates the performance of the MultifiltratePro in pediatric mode for Continuous Venovenous Hemodiafiltration (CVVHD) in children.
- Trial name
- ECHOped (NCT06603324)
- Testing
- CVVHD treatment in paediatric mode with multiFiltratePRO
- Where
- 2 sites in Czechia, Germany
- Volunteers
- 43 people
- Sponsor
- Fresenius Medical Care Deutschland GmbH
Acute Kidney Injury, Septic Shock
Prognostic Value Serum Concentration of Indoxyl Sulfate During Acute Kidney Injury in Septic Shock Patients.
The development of acute kidney injury (AKI) during septic shock is frequent and is associated with a high mortality rate. The reason of this increased mortality despite the use of renal replacement therapy is still unknown.
- Conditions
- Acute Kidney Injury, Septic Shock, Uremic; Toxemia, Mortality
- Trial name
- TOX-AKI (NCT03920982)
- Testing
- Determination of the blood concentration of indoxyl sulfate (IS)
- Where
- France
- Volunteers
- 114 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Acute Kidney Injury Due to Sepsis
Hemodynamic Resuscitation Guided by Non-Invasive Mean Systemic Filling Pressure to Prevent Acute Kidney Injury in Septic Shock
The goal of this clinical trial is to evaluate the efficacy of a hemodynamic resuscitation protocol guided by the Venous Return Gradient (Pmsf - CVP), measured via the non-invasive arm cuff technique, in reducing the incidence of…
- Trial name
- NCT07481097
- Testing
- Hemodynamic measurements during reduction in Norepinephrine and fluid boli.
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Assiut University
Kidney Transplant, Kidney Transplantation
Proteogenomic Biomarker Panels in a Serial Blood & Urine Monitoring Study of Kidney Transplant Recipients
There is a need to develop blood and/or urine tests that will help to detect early signs of rejection in people who have had kidney transplant.
- Trial name
- PROGENI-KI (NCT01289717)
- Where
- 5 sites in United States
- Volunteers
- 307 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Renal Function, Renal Injury
Analysis of Remote-ischemic Preconditioning Effects on Kidney Function
Patients with impaired renal function are at elevated risk for development of acute kidney injury (AKI). AKI is associated with increased risk for cardiovascular morbidity and mortality.
- Trial name
- RenPRO-TAVI (NCT01925235)
- Testing
- remote ischemic preconditioning
- Where
- Germany
- Volunteers
- 18 people
- Sponsor
- University of Cologne
Acute Kidney Injury
The Relationship Between IRRIV and RFR Under Pathologic Conditions
The assessment of renal functional reserve (RFR) has been proposed for the risk stratification of patients undergoing potentially nephrotoxic procedures.
- Trial name
- IRRIV-RFR (NCT03756376)
- Volunteers
- 31 people
- Sponsor
- Ospedale San Bortolo di Vicenza
Heart Failure, Congestive
PROTECT-1: A Study of the Selective A1 Adenosine Receptor Antagonist KW-3902 for Patients Hospitalized With Acute HF and Volume Overload to Assess Treatment Effect on Congestion and Renal Function
The study is being conducted to examine whether KW-3902IV will result in greater improvement in signs and symptoms of heart failure, with less treatment failure than standard therapy, when it is added to IV loop diuretics in…
- Trial name
- NCT00328692
- Testing
- rolofylline
- Volunteers
- 932 people
- Sponsor
- NovaCardia, Inc., a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA)
Cardiogenic Shock, Renal Replacement Therapy
REnal reCOVery After ECMO for Cardiogenic Shock (RECOVECMO)
This retrospective study assesses long term renal outcome in patients having suffered medical or post cardiotomy refractory cardiogenic shock requiring renal replacement therapy (RRT) concomitant with veno-arterial extracorporeal…
- Conditions
- Cardiogenic Shock, Renal Replacement Therapy, Venoarterial Extracorporeal Membrane Oxygenation
- Trial name
- RECOVECMO (NCT05788211)
- Testing
- standard of care
- Where
- France
- Volunteers
- 93 people
- Sponsor
- University Hospital, Bordeaux
Acute Abdomen, Radiocontrast Nephropathy
Intravenous Contrast Computed Tomography Versus Native Computed Tomography in Patients With Acute Abdomen and Impaired Renal Function
Computer tomography (CT) is the primary imaging option for acute abdominal pain in adults. Intravenous (IV) contrast media is used to improve the CT quality.
- Trial name
- INCARO (NCT04196244)
- Testing
- Abdominal or body CT with intravenous contrast, Abdominal or body CT without intravenous contrast (native CT)
- Where
- 3 sites in Finland
- Volunteers
- 994 people
- Sponsor
- Helsinki University Central Hospital
Acute Kidney Injury
UPTAKE - Virtual Care: Virtual Home Hospital With Remote Monitoring to Reduce Acute Care Hospitalization
Method: Randomized Controlled Trial Study Duration: 3 Years Study Centre(s) University of Calgary and University of Alberta Objectives: To fill care gaps by implementing strategies to reduce length of hospital stay, readmission…
- Trial name
- UPTAKE-VC (NCT06537453)
- Testing
- Virtual Care
- Where
- 2 sites in Canada
- Volunteers
- 354 people
- Sponsor
- University of Calgary
Contrast-induced Nephropathy
Coenzyme Q10 Role in Prevention of Contrast Induced Nephropathy in Acute Coronary Syndrome Patients.
In this study the investigators aim to study the effect of supplementation of CoQ10 in decreasing the incidence of contrast induced acute kidney injury in patients with acute coronary syndrome undergoing coronary angiography.
- Trial name
- NCT06429345
- Testing
- Coenzyme Q10 100 Milligrams Oral Capsule
- Where
- 2 sites in Egypt
- Volunteers
- 250 people
- Sponsor
- Ain Shams University
Kidney Failure, Acute
Effects of Endothelin Receptor Antagonist on Ischemic Kidney Injury During Nephron Sparing Surgery
Based on animal studies, it was found that administration of endothelial receptor antagonists before and after renal blood vessels clamp and release results in a significantly reduced renal function injury.
- Trial name
- NCT04450095
- Testing
- Ambrisentan 10 MG
- Where
- 2 sites in Israel
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Bnai Zion Medical Center
Chronic Kidney Diseases, Acute Kidney Injury
Use of New Drug QRX-3 for Prevention and Treatment of Chronic Kidney Disease Progression
Chronic kidney disease CKD is estimated to affect nearly over 800 million people globally today (with roughly 125,000 people ending up annually on dialysis in the United States alone.
- Conditions
- Chronic Kidney Diseases, Acute Kidney Injury, Kidney Failure
- Trial name
- NAD agent (NCT06866236)
- Testing
- QRX-3
- Where
- United States
- Volunteers
- 3,000 people
- Sponsor
- Ebima Clifford Okundaye
Renal Transplant
24 Months Follow-up, Two Arm Study to Compare the Cardiovascular Profile in a Regimen With Everolimus + Mycophenolic Acid (MPA) Versus (vs.) a Regimen of CNI+MPA in Maintenance Renal Transplant Recipients
The objective of the study is to compare the cardiovascular profile of an everolimus and mycophenolic acid immunosuppressive regimen with a calcineurin inhibitor and mycophenolic acid regimen in maintenance renal transplant…
- Trial name
- EVITA (NCT01169701)
- Testing
- Everolimus, Tacrolimus, Mycophenolic acid (MPA)
- Where
- 9 sites in Spain
- Volunteers
- 71 people
- Sponsor
- Novartis Pharmaceuticals
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