Clinical trials: Kidney Calculi Nephrolithiasis Urolithiasis Renal Stone
Renal Stone Disease, Kidney Calculi
The LARC Robot Simplifies Renal Access In Percutaneous Nephrolithotomy
This study is being done to evaluate a new robotic system that helps urologists more precisely reach the kidney during surgery to remove large kidney stones.
- Conditions
- Renal Stone Disease, Kidney Calculi, Refractory Kidney Stones, Kidney Stones
- Trial name
- NCT07211555
- Testing
- LARC Robotic System (Micromate™ Version 3.0)
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- AdventHealth
Renal Stone
Percutaneous Nephrolithotomy for Treatment of Kidney Stones Greater Than 2 cm
Percutaneous nephrolithotomy (PCNL) is a minimally invasive procedure considered as the treatment of choice for the management of large-scale and fully-formed kidney stones.This procedure has a 5% risk of complications including…
- Trial name
- NCT03189264
- Testing
- percutaneous nephrolithotomy for kidney stones
- Where
- Colombia
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Dr Carlos Hernández
Urinary (Renal or Ureteral) Stones
Comparison Between Two Shock Wave Regimens for Treating Urinary Stones
In order to check if a reduction in the frequency and total number of shocks delivered during extracorporeal shockwave lithotripsy (SWL) results in a great number of stone-free patients,the investigators compared two different…
- Trial name
- NCT01222325
- Testing
- extracorporeal shockwave lithotripsy (SWL)
- Where
- Brazil
- Volunteers
- 302 people
- Sponsor
- University of Sao Paulo General Hospital
Healthy Volunteers, Enteric Hyperoxaluria
Safety, Tolerability, and Pharmacodynamics of NOV-001 in Adult Subjects
The first stage of this study is a prospective, adaptive, Phase 1, first-in-human, randomized, controlled study evaluating safety, tolerability, and pharmacodynamics of NOV-001 in adult healthy volunteers.
- Trial name
- NCT04909723
- Testing
- NOV-001, NB1000S, NB2000P
- Where
- 20 sites in United States, Canada
- Volunteers
- 153 people, healthy volunteers welcome
- Sponsor
- Novome Biotechnologies Inc
Renal Stones, Retrograde Intrarenal Surgery
Safety of Thulium Fiber Laser Litothripsy in the Management of Large Renal Stones (>1000 mm³) and Factors Affecting Treatment Success
The aim of this study is to compare the efficacy and safety of Thulium Fiber Laser (TFL) litothripsy according to stone density and the factors affecting success in patients undergoing retrograde intrarenal surgery (RIRS) for…
- Conditions
- Renal Stones, Retrograde Intrarenal Surgery, Thulium Fiber Laser
- Trial name
- RIRS and TFL (NCT07153978)
- Testing
- Effectivity of TFL on large renal stone
- Where
- Turkey (Türkiye)
- Volunteers
- 81 people
- Sponsor
- Muharrem Baturu
Cystinuria, Nephrolithiasis, Calcium Oxalate
Use of an Herbal Preparation to Prevent and Dissolve Kidney Stones
We will investigate the safety and effectiveness of a mixture of 9 east Indian herbs known as Cystone regarding their ability to dissolve existing kidney stones and prevent formation of new ones.
- Trial name
- NCT00381849
- Testing
- Cystone
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Mayo Clinic
Obesity, Nephrolithiasis
Nephrolithiasis and Bariatric Surgery
Test the hypothesis that the new bariatric surgical procedures (BSP) increase stone risk, and will result in an increased incidence and prevalence of stone disease; the purpose is to determine if BSP patients require special…
- Trial name
- NCT00169793
- Testing
- evaluation of kidney stone risk after bariatric surgery, Evaluate risk of kidney stones after bariatric surgery
- Where
- United States
- Volunteers
- 89 people
- Sponsor
- Indiana Kidney Stone Institute
Kidney Stone
Influence of Obesity on Endogenous Oxalate Synthesis
There is increasing evidence that obesity is associated with increased urinary oxalate excretion, an important risk factor for calcium oxalate stone formation.
- Trial name
- NCT03704350
- Testing
- controlled diet
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Urolithiasis, Urologic Diseases
Effectiveness of Drainage by PCN vs. JJ in Patients With Symptoms of Obstructive Kidney Disease Caused by Urolithiasis
To investigate the effectiveness of percutaneous nephrostomy catheter placement versus retrograde double J catheter placement in patients with symptoms of obstructive kidney disease (with either infection and/or pain and/or…
- Conditions
- Urolithiasis, Urologic Diseases, Urinary Calculi, Urinary Obstruction
- Trial name
- STONE (NCT04594161)
- Testing
- Percutaneous Nephrostomy, Double J catheter
- Where
- Netherlands
- Volunteers
- 204 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Renal Stones, Calculus
Comparison of ESWL and Mini-PCNL for High-Density Renal Stones in Children
Pediatric nephrolithiasis is an increasing health problem, with rising prevalence particularly in certain geographic regions. Management options for pediatric renal stones include extracorporeal shockwave lithotripsy (SWL)…
- Conditions
- Renal Stones, Calculus, Pediatric, Endoscopy
- Trial name
- NCT07360041
- Testing
- Miniaturized Percutaneous Nephrolithotomy (mini-PNL), Shock Wave Lithotripsy (SWL)
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Ain Shams University
Urolithiasis, Renal Colic
Metabolic Workup in Patients Suffering From Kidney Stone Disease and Osteopenia
Patients suffering from acute renal colic are evaluated by non contrast computerized tomography with excellent identification rates of urinary stones.
- Conditions
- Urolithiasis, Renal Colic, Osteopenia
- Trial name
- NCT04080973
- Testing
- CT scan, 24 hour urine collection
- Where
- Israel
- Volunteers
- 150 people
- Sponsor
- Ziv Hospital
Renal Stone
Stone Clearance in Patients With Upper Ureteric Stones Using Extracorporeal Shock Wave Lithotripsy Compared With Extracorporeal Shock Wave Lithotripsy Combined With Tamsulosin Therapy
Extracorporeal shock wave lithotripsy (ESWL) is the least invasive and effective treatment for upper ureteric stones with a stone clearance rate of 60-90%.
- Trial name
- NCT05725122
- Testing
- Extracorporeal shock wave lithotripsy, Extracorporeal Shock Wave Lithotripsy combined with Tamsulosin Therapy.
- Where
- Pakistan
- Volunteers
- 82 people
- Sponsor
- Services Hospital, Lahore
Urolithiasis
Renal Stone Treatment Global Registry
This is an international prospective data registry to assess the treatment outcomes and complications of different treatment approaches for different surgical treatment of urolithiasis.
- Trial name
- NCT05297331
- Where
- 3 sites in Hong Kong
- Volunteers
- 3,000 people
- Sponsor
- Chinese University of Hong Kong
Kidney Calculi, Quality of Life
Quality of Life in Kidney Stone Patients Undergoing Surgery
This is a prospective randomized study, comparing quality of life in renal stone patients undergoing surgical treatment with ureteroscopy (URS) versus percutaneous nephrolithotomy (PNL).
- Trial name
- NCT02625051
- Testing
- Ureteroscopy, Percutaneous nephrolithotomy
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of California, San Francisco
Kidney Calculi, Nephrolithotomy, Percutaneous
Bilateral Synchronous Simultaneous Stone Surgery
Advancements in technology and endourological armamentarium provides multiple surgical options for complicated stone patients. To avoid multiple operations and shorten the total operation durations, bilateral synchronous…
- Conditions
- Kidney Calculi, Nephrolithotomy, Percutaneous, Ureteroscopy
- Trial name
- NCT03599297
- Testing
- Bilateral synchronous simultaneous stone surgery
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Marmara University
Urolithiasis, Kidney Stone
Comparing Efficacy and Complication Between Prone Versus Prone-Flexed Position for Percutaneous Nephrolithotomy (PCNL)
Comparing Efficacy and Complication Between Prone Versus Prone-Flexed Position For Percutaneous Nephrolithotomy (PCNL)
- Conditions
- Urolithiasis, Kidney Stone, Complication
- Trial name
- NCT06624306
- Testing
- Prone PNL, Prone-flexed PNL
- Where
- Egypt
- Volunteers
- 85 people
- Sponsor
- Fayoum University Hospital
Urolithiasis, Nephrolithiasis
Validation of the Wisconsin Stone-QOL
The overall purpose of this study is to evaluate criterion-related validity of a newly-developed disease-specific instrument to assess the health-related quality of life (HRQOL) of patients who have had kidney stones.
- Conditions
- Urolithiasis, Nephrolithiasis, Kidney Stones
- Trial name
- NCT02188108
- Testing
- Wisconsin Stone-QOL survey
- Where
- United States
- Volunteers
- 3,299 people
- Sponsor
- University of Wisconsin, Madison
Kidney Calculi, Pain, Postoperative
Pre-induction Analgesia: Multimodel Regimen vs Aceteminophen for Post Ureteroscopy Pain
Adult patients with kidney stones undergoing surgical intervention with ureteroscopy with laser lithotripsy will be randomized to receive one of two different regimens of oral medications administered prior to induction of…
- Trial name
- MMPITR (NCT03549611)
- Testing
- Multimodal Oral Drug Regimen, Acetaminophen
- Sponsor
- Kevin J Flynn MD
Recurrent Calcic Urolithiasis
Renalof in the Dissolution of Renal Calculi in Patients With Recurrent Calcic Lithiasis
The purpose of this study is to determine whether Renalof administration promotes partial or total dissolution of urinary calculi and improves physicochemical parameters and metabolic activity in patients with recurrent calcic…
- Trial name
- NCT01022060
- Testing
- Renalof
- Where
- Cuba
- Volunteers
- 110 people
- Sponsor
- Catalysis SL
Kidney Stones
Flexible Ureteroscopy Versus Extracorporeal Shock Wave Lithotripsy
To compare the efficacy and safety of flexible ureterorenoscopy (fURS) versus extracorporeal shock wave lithotripsy (ESWL) in managing lower calyceal renal stones ≤15 mm and <1000 HU.
- Trial name
- NCT07193940
- Testing
- Flexible Ureteroscopy, extracorporeal shock wave lithotripsy (ESWL)
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Assiut University