Clinical trials: Kidney Stone Prevention
Kidney Calculi, Crohn's Disease
Calcium Supplements Strategy for Kidney Stones Prevention in Crohn's Patients
Hospitalization for kidney stones in the Inflammatory Bowel Disease (IBD) population is common, particularly among Crohn's patients who had a small bowel resection.
- Trial name
- NCT01735461
- Testing
- Calcium Carbonate
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- University of British Columbia
Kidney Stone Prevention
Protein Sources Urinary Stone Risk
Prior studies have shown that the source of dietary protein can have a significant impact on urinary stone risk. However, whey and plant protein isolates have not been compared.
- Trial name
- NCT05460247
- Testing
- Protein
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Kidney Calculi, Nephrolithiasis
Patient Compliance for Metabolic Evaluation and Medical Management in Calcium Stone Patients
Calcium oxalate stone, the most common type worldwide, has a recurrence rate of around 50% in ten years. Therefore, identifying the underlying pathophysiological aspects via metabolic evaluation and suggestions for medical \&…
- Conditions
- Kidney Calculi, Nephrolithiasis, Patient Compliance, Calcium Oxalate Urolithiasis
- Trial name
- NCT04169165
- Volunteers
- 500 people
- Sponsor
- EULIS Colloborative Research Working Group
Kidney Calculi
Role of Medication in Making Urine Less Acidic as Part of Kidney Stone Prevention
Diet and medications are the cornerstones of kidney stone prevention. Potassium citrate is a commonly prescribed medication to help prevent kidney stones by making urine less acidic.
- Trial name
- NCT06819111
- Testing
- Potassium Citrate Extended Release Oral Tablet
- Volunteers
- 20 people
- Sponsor
- University of Texas Southwestern Medical Center
Urinary Stones
Prevention of Urinary Stones With Hydration
A randomized clinical trial to investigate the impact of increased fluid intake and increased urine output on the recurrence rate of urinary stone disease (USD) in adults and children.
- Trial name
- PUSH (NCT03244189)
- Testing
- Fluid prescription, Financial incentive, Structured Problem Solving
- Where
- 8 sites in United States
- Volunteers
- 1,658 people
- Sponsor
- Duke University
Kidney Stones, Urolithiasis, Hypocitraturia
Apple Cider Vinegar for the Prevention of Urinary Lithiasis (APUL)
The purpose of this study is to assess whether certain beverages can increase urinary citrate levels in healthy individuals with no history of kidney disease.
- Trial name
- APUL (NCT04073719)
- Testing
- Apple Cider Vinegar, Other Beverage
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- United States Naval Medical Center, San Diego
Nephrolithiasis
Hydrochlorothiazide for Kidney Stone Recurrence Prevention
The investigators plan to assess the efficacy of standard and low dose HCTZ treatment in the recurrence prevention of calcium-containing kidney stones.
- Trial name
- NOSTONE (NCT03057431)
- Testing
- 12.5 mg hydrochlorothiazide, 25.0 mg hydrochlorothiazide, 50.0 mg hydrochlorothiazide
- Where
- 12 sites in Switzerland
- Volunteers
- 416 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Urinary Tract Stone
Effectiveness of WhatsApp Education and Support Messages for Urolithiasis Prevention
Kidney and ureteral stones are a common problem in primary care practice with increasing prevalence over the last few decades. Prevention of recurrent stones (which are usually composed primarily of calcium oxalate) is aimed at…
- Trial name
- StoneApp (NCT05627622)
- Testing
- WhatsApp health education message
- Where
- Israel
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Rabin Medical Center
Nephrolithiasis
Nephrolithiasis Prevention by Lemon Juice
Calcium oxalate nephrolithiasis is a relatively common disease. The prevalence in the general population may range from 10 to 12 percent, and 0.4 to 1 percent of new cases are reported every year according to different series.
- Trial name
- LIMONE (NCT01217372)
- Testing
- Lemon supplementation
- Where
- Italy
- Volunteers
- 203 people
- Sponsor
- Mario Negri Institute for Pharmacological Research
Renal Stones, Idiopathic Hypercalciuria
Use of Nanotechnology Structured Water for the Prevention of Recurrent Stone Formation
We assessed the effect of structured nano-water in the prevention of recurrent stone formation in patients with recurrent calcium oxalate stones and hypercalciuria.
- Trial name
- NCT06681116
- Testing
- structured nano-water, Hydrochlorothiazide (HCTZ), ordinary bottled drinking water
- Where
- Iraq
- Volunteers
- 325 people
- Sponsor
- ALI KAMAL M. SAMI
Urolithiasis, UTI
Antibiotic Prophylaxis With Routine Ureteral Stent Removal
This study will be a single-institutional randomized, single-blinded prospectively controlled clinical trial of a single dose of Ciprofloxicin 500mg antibiotic tablet as prophylaxis at the time of office flexible cystoscopy with…
- Trial name
- STENTABX (NCT02944825)
- Testing
- Ciprofloxacin, trimethoprim/sulfamethoxazole, No Intervention
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- University of California, San Diego
Kidney Stone
Treatment Optimization and Nephrolithiasis Recurrence Prevention With Interdisciplinary Care
Nearly 10% of the Belgian population suffer from kidney stone disease. Recent reviews reported that kidney stones represent an underestimated risk factor for further kidney function deterioration.
- Trial name
- NCT06367894
- Where
- Belgium
- Volunteers
- 164 people
- Sponsor
- Agnieszka Pozdzik
Ureteral Stones, Ureteral Calculi
Antibiotic Prophylaxis Before Shock Wave Lithotripsy
This is a two arm, double blind RCT comparing the use of a single dose ciprofloxacin prior to SWL to saline alone. The multicenter trial will be conducted with a pragmatic emphasis including both high volume and low volume sites…
- Conditions
- Ureteral Stones, Ureteral Calculi, Nephrolithiasis
- Trial name
- APPEAL (NCT03692715)
- Testing
- Ciprofloxacin
- Where
- 10 sites in Brazil, Canada and 7 more
- Volunteers
- 1,732 people
- Sponsor
- Clinical Urology and Epidemiology Working Group
Kidney Stone
Indapamide and Chlorthalidone to Reduce Urine Supersaturation for Kidney Stone Prevention
The aim of this study is to test the efficacy of the two long-acting thiazide-like diuretics indapamide and chlorthalidone in reducing urine supersaturation for calcium oxalate and calcium phosphate compared to the short-acting…
- Trial name
- INDAPACHLOR (NCT06111885)
- Testing
- Indapamide 2.5 MG, Hydrochlorothiazide 50Mg, Chlorthalidone 25mg
- Where
- Switzerland
- Volunteers
- 99 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Kidney Stone, Hypernatriuria
Software Application for Low-Sodium Diet Trial (SALT)
This a single-center prospective randomized controlled trial. Subjects will be assigned to the standard of care dietary recommendations for a low sodium diet (LSD) vs.
- Trial name
- NCT04438551
- Testing
- Standard dietary counseling, Mobile app
- Where
- United States
- Sponsor
- University of Rochester
Hypouricemia, Renal, Urolithiasis
A Randomized Clinical Trail of The Effect of Postoperative Uric Acid Control on Stone Recurrence and Renal Function in Patients With Hyperuricemia of Urolithiasis.
The purpose of this study was to explore the effects of uric acid control on stone recurrence and renal function in patients with calculi of hyperuricemia through a prospective controlled study.
- Trial name
- NCT04398251
- Testing
- Febuxostat 40mg Tab, Non-drug control group
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Xuhui Central Hospital, Shanghai
Kidney Stones, Nephrolithiasis
Empiric Versus Selective Prevention Strategies for Kidney Stone Disease
The aims of this study are to 1) Conduct a randomized clinical trial of selective versus empiric diet plus pharmacologic therapy in high-risk stone formers and 2) Determine adverse effects from, and adherence to selective and…
- Trial name
- NCT05365477
- Testing
- Empiric Therapy: Diet, Empiric Therapy: Drug, Selective Therapy: Diet
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- Vanderbilt University Medical Center
Kidney Stones
Comparison of Multiple-, Single- and Zero-dose of Ciprofloxacin Prophylaxis in Retrograde Intrarenal Surgery
The purpose of this study is to compare the postoperative systemic inflammatory response syndrome (SIRS) rates undergoing retrograde intrarenal surgery (RIRS) after multiple-, single-, zero-dose of ceftriaxone prophylaxis in a…
- Trial name
- RIRS (NCT02304822)
- Testing
- Multiple-dose of Ciprofloxacin prophylaxis, Single-dose of Ciprofloxacin prophylaxis, Zero-dose of Ciprofloxacin prophylaxis
- Where
- China
- Volunteers
- 450 people
- Sponsor
- Guohua Zeng
Nephrolithiasis
Mature Vinegar Prophylaxis Against Recurrent Calcium Oxalate Nephrolithiasis
Kidney stones are one of the most common disorders of the urinary tract and cause a great deal of morbidity and economic loss. Because of the high recurrence rate, researchers are interested in finding medicinal therapies to…
- Trial name
- NCT03092908
- Testing
- mature vinegar
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- The First Affiliated Hospital of Guangzhou Medical University
Renal Stone
Enhanced Versus Extended Preoperative Antibiotic Prophylaxis Regimens for Retrograde Intrarenal Surgery in High Infectious Risk Patients
In the available literature, there is a lack the risk categorization of infectious complications after RIRS with subsequent recommendation as regard to AP in different risk patients.
- Trial name
- NCT05384197
- Testing
- Enhanced regimen, Extended regimen
- Where
- Egypt
- Volunteers
- 280 people
- Sponsor
- Mansoura University