Clinical trials: Knee
Quadriceps Muscle
Macroscopic and Molecular Changes in Knee Muscular-tendon Unit in Response to Acute Resistant Load
The aim of this study is to determine the influence of acute resistance exercises on anatomical and biological changes in the quadriceps muscle and tendons of the knee
- Trial name
- NCT03950596
- Testing
- Acute resistant load exercises, Background Questionnaire, Pain Questionnaire
- Where
- Israel
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Hillel Yaffe Medical Center
Postural Stability, Dynamic Knee Valgus
The Effect Subtalar Joint Pronation on Postural Stability and Lower Extremity Alignment
The lower extremity consists of sequent columns. The deviation of one segment from its normal alignment in the lower extremity also affects the alignment of the other segments.
- Conditions
- Postural Stability, Dynamic Knee Valgus, Injury Prevention
- Trial name
- NCT05606835
- Testing
- Postural stability assessment, Frontal plan prjection angle, Foot and Ankle Ability Measure
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Bahçeşehir University
Arthritis of the Knee
A Randomized, Study to Evaluate the Iovera° Device in Treating Pain Associated With Total Knee Arthroplasty
This study will evaluate the iovera° device in treating pain associated with total knee arthroplasty (TKA). This study will also assess if overall pain medication is reduced following TKA and will investigate the relationship…
- Trial name
- NCT02284113
- Testing
- iovera°
- Where
- 8 sites in United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Pacira Pharmaceuticals, Inc
Knee Osteoarthritis (Knee OA)
To Assess the Effect of 336 Days Exposure of Paractin® on Pain & Disease Progression in Patients Suffering From Osteoarthritis of Knee Joint.
Sponsor aimed to study hydroalcoholic extract of Andrographis paniculata (for its effect on OA disease progression in OA patients with moderate to severe knee OA.
- Trial name
- NCT04833946
- Testing
- Andrographis paniculata [150 mg], Microcrystalline Cellulose (MCC)
- Where
- 5 sites in India
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Vedic Lifesciences Pvt. Ltd.
Arthroplasty, Replacement
Walking Stick Exercise in Patients Underwent Total Knee Arthroplasty
The purpose of this study is to examine whether the effect of "hiking poles exercise" on lower extremity muscular strength, knee range of motion, and quality of life in elderly patients underwent total knee arthroplasty
- Conditions
- Arthroplasty, Replacement, Knee Osteoarthritis
- Trial name
- NCT05030662
- Testing
- Walking stick exercise
- Where
- Taiwan
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- National Taipei University of Nursing and Health Sciences
Anterior Cruciate Ligament Injuries
Individualized Anterior Cruciate Ligament Versus Conventional Reconstruction
A randomised prospective control trial comparing the efficiency of a more individualized approach in ACL reconstruction with the help of neuromuscular computer models with traditional ACL reconstruction practices.
- Trial name
- IACLR (NCT04366362)
- Testing
- Individualised ACL reconstruction, Conventional ACL reconstruction
- Where
- Greece
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Larissa University Hospital
Reliability and Validity, Smartphone
Reliability and Validity of iPhone Application for OBER
The validity and reliability of adduction angle measurement of hip with smartphone will be investigate.
- Conditions
- Reliability and Validity, Smartphone, Iliotibial Band Syndrome
- Trial name
- NCT04787900
- Testing
- iPhone measurement application, Bubble inclinometer
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- KTO Karatay University
Anterior Cruciate Ligament Tear
Bridge-Enhanced ACL Repair vs ACL Reconstruction
The goal of this trial is to compare the efficacy of the Bridge-Enhanced Anterior Cruciate Ligament Repair (BEAR™) technique with the current method of treatment for anterior cruciate ligament (ACL) injuries, ACL reconstruction.
- Trial name
- NCT02664545
- Testing
- BEAR Scaffold, Tendon Graft
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Miach Orthopaedics
Knee Instability in Total Knee Artrhroplasty
Knee Arthroplasty Instability Study
Total knee replacement (TKR) instability is a poorly defined entity. The diagnosis is based on symptoms and clinical tests of knee laxity.
- Trial name
- KISS (NCT05676437)
- Testing
- Stress radiography
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Diakonhjemmet Hospital
Genu Varum
Hemiepiphysiodesis by Eight Plate Versus Osteotomy in the Management of Pediatric Coronal Knee Deformities
Coronal angular deformities of lower limb in children are a common finding in pediatric orthopedic surgery.These angular deformities can be idiopathic in origin, or they can emerge secondary to congenital and acquired…
- Trial name
- NCT06630975
- Testing
- Hemiepiphysiodesis, Eight-Plates first described by Stevens are simple to use, Hemiepiphysiodesis by eight Plate
- Where
- Egypt
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Knee Ligament Injury
TEL and Clam Shell Exercises Affect After ACL
The purpose of this study to determine the effects of the addition of isolated hip strengthening exercises to traditional rehabilitation after Anterior cruciate ligament reconstruction (ACLR).
- Trial name
- NCT05856071
- Testing
- goniometer, clamshells exercises, traditional physical therapy
- Where
- Pakistan
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Knee Arthropathy, Arthroplasty Complications
l Investigation of Robotic-assisted TKA (RA-TKA) With Skywalker and Evolution Medial Pivot Knee (eMP Knee)
This is a prospective trial that attempts to develop evidence on the safety and performance of RA-TKA (Robotic-assisted total knee arthroplasty) with Skywalker and eMP (Evolution Medial Pivot) knee.
- Conditions
- Knee Arthropathy, Arthroplasty Complications, Robotic Assisted Arthroplasty, TKA Outcomes
- Trial name
- NCT06969222
- Testing
- Robotic TKA, Conventional TKA
- Where
- Greece
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- Orthopaedic Department of General University Hospital of Laria
Wound Heal, Wound Dehiscence
Wound Closure After Total Knee Arthroplasty: Comparison of Polypropylene and Polyglactin 910 Suture.
Comparison of wound complication and scar formation in patient undergone bilateral total knee replacement comparison between polypropylene and polyglactin 910 suture.
- Conditions
- Wound Heal, Wound Dehiscence, Wound Complication
- Trial name
- NCT06373900
- Testing
- wound closure
- Where
- Pakistan
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Indus Hospital and Health Network
Infection
Infection Prevention After TKA With or Without Vancomycin
Prospective, Randomized, Double Blinded Trial Comparing Clinical, Radiological and Laboratory Outcomes in prevention of infection after Total Knee Arthroplasty With or Without Vancomycin.
- Trial name
- TKA_Vanco (NCT05461651)
- Testing
- Knee arthroplasty
- Where
- Poland
- Volunteers
- 1,800 people, healthy volunteers welcome
- Sponsor
- Centre of Postgraduate Medical Education
Anterior Cruciate Ligament Injuries, Quadriceps Muscle Atrophy
The Effects of Whole-body Vibration on Increasing Quadriceps Strength in Patients With ACL Ruptures
Introduction: Approximately 35% patients can not return to sports after anterior cruciate ligament reconstruction(ACLR). Persistent quadriceps weakness is a factor that prevents patients return to sports.
- Trial name
- NCT04988828
- Testing
- Whole body vibration
- Where
- Hong Kong
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Caregiver
Program Based on the Family-Centered Empowerment Model on Total Knee Prosthesis Patients and Their Caregivers
In this study, the family empowerment model program given to individuals who underwent Total Knee Prosthesis and their caregivers was examined on the individuals' physiological function level, self-efficacy, and post-discharge…
- Trial name
- NCT06402539
- Testing
- family-centered empowerment program
- Where
- Turkey (Türkiye)
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Selcuk University
Total Knee Replacement
Innovative Gait Training for People With Knee Osteoarthritis Using Dual Belt Treadmill
Knee osteoarthritis (OA) is the most common form of arthritis and is the leading cause of chronic musculoskeletal pain and functional disability. Gait assessment is essential for the rehabilitation of people with knee OA.
- Trial name
- NCT05958212
- Testing
- Gait training program, Conventional training only
- Where
- Hong Kong
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Muscles Ischemia
Clinical, Biochemical and Neurophysiological Consequences of Intraoperative Tourniquet During Total Knee Arthroplasty
Clinical, Biochemical and Neurophysiological Consequences of Intraoperative Tourniquet During Total Knee Arthroplasty: WOMAC-Score Knee-Score Radiographic Evaluations and Scoring System Biochemical muscle biopsy analysis
- Trial name
- NCT02475603
- Testing
- Total knee arthroplasty
- Where
- Germany
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Universitätsmedizin Mannheim
Knee Bone Marrow Lesions
New Topographic Classification of Knee Bone Marrow Lesions
the investigator are studying a new topographic classification of bone marrow lesion in the knee and validating it.
- Trial name
- ncbe (NCT03976141)
- Testing
- mri
- Where
- Italy
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- University of Milan
Anesthesia, Total Knee Arthroplasty
The Efficacy of Peripheral Nerve Blocks With Intrathecal Morphine in Improving Analgesia After Unilateral Total Knee Arthroplasty
The purpose of this study is to determine whether intrathecal morphine (ITM) alone or its combination with peripheral nerve blocks (PNB) provides better analgesia for patients undergoing total knee arthroplasty (TKA).
- Trial name
- NCT02135120
- Testing
- Combined spinal epidural anesthesia technique with intrathecal morphine, A combination of combined spinal-epidural (with intrathecal morphine) and femoral nerve block, A combination of combined spinal-epidural (with intrathecal morphine) and femoral nerve block as well as sciatic nerve block
- Where
- Lebanon
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- American University of Beirut Medical Center
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