Clinical trials: Knee Joint Loading
Single Leg Hop Sand Surface, Single Leg Hop Grass Surface
Effect of Sand on Knee Load and Muscle Activity During a Single Leg Landing Task
This study evaluates the effect of different surfaces on the load experienced by the knee when landing from a single leg hop. A sand, pliable grass and firm (hard floor) surface will be compared when hopping from a 30 cm height.
- Conditions
- Single Leg Hop Sand Surface, Single Leg Hop Grass Surface, Single Leg Hop Firm Surface
- Trial name
- NCT04502615
- Testing
- Sand, artificial grass, firm ground
- Where
- United Kingdom
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Teesside University
Osteoarthritis, Knee, Knee Pain Chronic
Effectiveness of a Walking Intervention on Impact Loading and Pain
This study investigates the feasibility of a gait-retraining program for older adults with knee osteoarthritis. The study will enroll 40 participants, with 20 receiving a gait retraining intervention and 20 receiving a graded…
- Trial name
- NCT04148807
- Testing
- Progressive Walking with Gait Retraining, Progressive Walking Program
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Northeastern University
Knee Osteoarthritis
Effects of a New Knee Brace for Treatment of the Knee Osteoarthritis
The purpose of this study is to evaluate the immediate effects of a knee brace with a new mechanism on the pain and medial knee loading during gait among medial knee osteoarthritis patients.
- Trial name
- NCT01866176
- Testing
- Stabilizing Knee Brace, Valgus Knee Brace, New Knee Brace
- Where
- Canada
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Laval University
Knee Osteoarthritis
A Novel Walking Cane With Haptic Biofeedback Reduces Degenerative Loading in the Arthritic Knee
The most commonly prescribed mobility aid, the walking cane, is often underloaded and therefore fails to reduce knee joint loading and provide symptomatic relief for those with knee osteoarthritis.
- Trial name
- NCT03900052
- Testing
- Haptic cane, typical cane
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- VA Puget Sound Health Care System
Osteoarthritis of the Knee
LOW LOAD RESISTANCE BLOOD FLOW RESTRICTION TRAINING VERSUS NEUROMUSCULAR TRAINING IN KNEE OSTEOARTHRITIS
This study will be conducted to compare the effect of BFR with LLRT versus neuromuscular training on quadriceps muscle strength, knee joint function and proprioception accuracy.
- Trial name
- NCT04600661
- Testing
- Traditional exercise therapy
- Volunteers
- 63 people
- Sponsor
- Mai Mohamed Abdelkader Abdallah
Osteoarthritis, Articular Cartilage Disorder of Knee
Serum Cartilage Oligomeric Matrix Protein Levels After 12 Weeks of Different Exercises
Acute effects of physical exercise on the deformational behavior of articular cartilage and changes in cartilage oligomeric matrix protein (COMP) are definite.
- Conditions
- Osteoarthritis, Articular Cartilage Disorder of Knee, Degenerative Lesion of Articular Cartilage of Knee
- Trial name
- NCT01576159
- Testing
- Running exercise, Cycling exercise, Swimming Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Middle East Technical University
Total Knee Arthroplasty
Low-Load Blood Flow Restriction Training With Patients Who Underwent a Total Knee Arthroplasty: a Feasibility Trial
This project aims to investigate the feasibility of a low load (LL) isokinetic knee flexor and extensor strength training (ST) protocol under blood flow restriction (BFR) conditions in early postoperative total knee arthroplasty…
- Trial name
- NCT05843773
- Testing
- Low Load Strength Training under Blood Flow Restriction
- Where
- Switzerland
- Volunteers
- 7 people
- Sponsor
- HES-SO Valais-Wallis
Osteoarthritis, Hip Infection
Study of Antibiotic Spacer Design to Treat Infection After Hip Replacement
Infection remains one of the most difficult-to-treat complications of total hip arthroplasty. The gold standard treatment is two-stage removal of the prosthesis with later replacement of permanent implants.The first stage…
- Conditions
- Osteoarthritis, Hip Infection, Prosthetic Joint Infection, Complications; Arthroplasty, Infection or Inflammation
- Trial name
- SPACERHIP (NCT01373099)
- Testing
- Implantation of a static, non-articulating cement spacer., Implantation of an articulating spacer.
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Rush University Medical Center
Hypermobility, Joint, Hypermobility Syndrome
Exercise in Patients With Hypermobile Joints and Knee Pain
Pain associated with knee joint hypermobility is common in the adult population, but evidence on treatment is sparse. This study investigates if high-load resistance training is superior to usual care in improving…
- Conditions
- Hypermobility, Joint, Hypermobility Syndrome, Knee Discomfort
- Trial name
- HIPEr-Knee (NCT06277401)
- Testing
- Neuromuscular training for the knee, High-load strength training for the knee
- Where
- 2 sites in Denmark
- Volunteers
- 80 people
- Sponsor
- University of Southern Denmark
Pediatric Obesity, Lower Extremity Biomechanics
Training Induced Reduction of Lower-limb Joint Loads During Locomotion in Obese Children
Childhood obesity is one of the most critical and accelerating health challenges throughout the world. It is a major risk factor for developing varus/valgus misalignments of the knee joint.
- Trial name
- NCT02545764
- Testing
- Strength and neuromuscular exercise programme
- Where
- Austria
- Volunteers
- 48 people
- Sponsor
- St. Pölten University of Applied Sciences
Knee Osteoarthritis
Descriptive Study of Knee Joint Pain During Strength Training After Total Knee Arthroplasty
Background: In the early phase after a total knee arthroplasty (TKA), patients experience multi-level weakness in the operated leg, which is caused primarily by reduced central nervous system (CNS) activation failure of the…
- Trial name
- NCT01729520
- Testing
- Knee extension strength training
- Where
- Denmark
- Volunteers
- 15 people
- Sponsor
- Hvidovre University Hospital
Anterior Cruciate Ligament Injuries, Cartilage Degeneration
The Mechanism for the Effects of Joint Biomechanical Properties on Medial Cartilage of Tibiofemoral Joint Degeneration
Explore The Mechanism for the Effects of Joint Biomechanical Properties on Medial Cartilage of Tibiofemoral Joint Degeneration
- Trial name
- NCT04968665
- Testing
- gait testing, functional MRI
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Peking University Third Hospital
Osteoarthritis, Knee
Atlas Knee System Clinical System Clinical Study (USA)
The primary objective of this pilot study is to collect data on the safety and effectiveness of the Atlas Knee System in subjects with medial knee osteoarthritis through 24 months postoperative follow-up.
- Trial name
- Atlas-USA (NCT02934659)
- Testing
- Atlas(TM) Knee System
- Where
- 9 sites in United States
- Volunteers
- 50 people
- Sponsor
- Moximed
Pes Anserine Bursitis
Comparison of Bracing and Eccentric Loading Exercises on Pain Modulation and Functional Improvement in Acute Pes Anserine Bursitis Patients
This study aims to compare the effects of knee bracing and eccentric loading exercises on pain and functional ability in adults with acute pes anserine bursitis.
- Trial name
- NCT07881913
- Testing
- Medial-Support Knee Brace, Eccentric Loading Exercise
- Where
- 2 sites in Pakistan
- Volunteers
- 32 people
- Sponsor
- Dr Aneeqa Sultan
Knee Injury
Evaluation of a Composite Cancellous and Demineralized Bone Plug (CR-Plug) for Repair of Knee Osteochondral Defects
The objective of this study is to determine how effective a plug made out of human bone (called "CR-Plug") will be in the treatment of smaller, focal defects (like the injury the patient has to their knee).
- Trial name
- NCT00984594
- Testing
- Primary injury site, Backfill site
- Where
- United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- RTI Surgical
Healthy
Muslce Oxygenation of the Quadricep Relative to Angle and Load
The purpose of the present study is to determine if the amount of oxygen in muscles during resistance exercise with different weights is related to changes in torque or knee joint angle.
- Trial name
- MORAL (NCT06638788)
- Testing
- Knee extension
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Knee Osteoarthritis
Effectiveness of a Knee Brace When Combined With Viscosupplementation in the Treatment of Knee Osteoarthritis
Hypothesis: Viscosupplementation when combined with an off-loading knee brace is more effective in treating the symptoms of knee OA then treating with viscosupplementation alone
- Trial name
- NCT01478386
- Testing
- Orthovisc, DonJoy HA lite knee brace, Orthovisc injections and DonJoy HA lite knee brace
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- OAD Orthopaedics