Clinical trials: Knee Osteoarthristis
Knee Osteoarthristis
Blood Flow Restriction Training in Knee Osteoarthritic Patients
The aim of this study was to compare the effect of band tissue flossing method and traditional cuff method for blood flow restriction training on pain, range of motion, muscle strength and functional status in patients with knee…
- Trial name
- NCT07402408
- Testing
- Blood flow restriction training with Floss band, Blood flow restriction training with pneumatic cuff
- Where
- Pakistan
- Volunteers
- 46 people
- Sponsor
- Riphah International University
Knee Osteoarthritis, Knee Osteoarthritis (Knee OA)
Reflexology and Mulligan Mobilization for Knee Osteoarthritis
to investigate the effect of adding Reflexlogy to mulligan mobilization and the conventional treatment for patients with Osteoarthritis knees
- Trial name
- NCT06815016
- Testing
- Reflexology ,mulligan mobilization and conventional, reflexology and conventional, mulligan mobilization and conventional
- Where
- Egypt
- Volunteers
- 84 people
- Sponsor
- Cairo University
Knee Osteoarthristis
Precision Rehabilitation: Mechanisms and Efficacy of Vibration in Exercise Training for Degenerative Knee Osteoarthritis
Knee osteoarthritis (OA) is a common degenerative disease in older populations. Chronic pain, quadriceps weakness, limited daily activities, lack of mobility, and balance and walking dysfunction are the most common symptoms.
- Trial name
- NCT06616896
- Testing
- vibration
- Where
- Taiwan
- Volunteers
- 50 people
- Sponsor
- National Taiwan University Hospital
Knee Osteoarthristis, Hyaluronic Acid
The Efficacy and Safety of a Single-Dose Hyaluronic Acid Injection in the Treatment of Knee Osteoarthritis
HA therapy typically consists of several intra-articular injections administered at weekly intervals. A single-dose IA-HA treatment offers patients and physicians a treatment option that involves both lower costs and fewer clinic…
- Trial name
- ESSDHAITKO (NCT07487038)
- Testing
- Intra-articular hyaluronic acid injection
- Where
- Turkey (Türkiye)
- Volunteers
- 133 people
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital
Knee Osteoarthristis
Effects of Whole-Body Vibration in Patients With Knee Osteoarthritis.
Knee osteoarthritis is a chronic joint disease with an impact on quality of life and an increasing incidence what leads to huge costs and burden on the economy.
- Trial name
- NCT06662682
- Testing
- Whole-Body Vibration, Control Condition
- Where
- Germany
- Volunteers
- 20 people
- Sponsor
- University of Erlangen-Nürnberg Medical School
Knee Osteoarthristis
Skeletal Muscle Atrophy and Dysfunction Following Total Knee Arthroplasty
Total knee replacement, or arthroplasty, is the final clinical intervention available to relieve pain and functional limitations related to advanced stage knee osteoarthritis.
- Trial name
- NCT03051984
- Testing
- Neuromuscular electrical stimulation
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- University of Vermont
Inflammatory Articular Diseases, Knee Osteoarthristis
"Transarterial Microembolization (TAME) in Inflammatory Knee Pathology"
Patients with knee OA and chronic pain refractory to at least 3 months of conventional conservative therapy will be included in the study, which will evaluate the clinical results obtained after treatment with selective arterial…
- Trial name
- TAME-OA (NCT07140367)
- Testing
- Transarterial Microembolization
- Where
- Italy
- Volunteers
- 43 people
- Sponsor
- Istituto Ortopedico Rizzoli
Knee Osteoarthristis, Gonarthrosis
Different Ozone Concentrations for Knee Osteoarthritis
Knee osteoarthritis is a common condition that causes pain, stiffness, and difficulty with daily activities. Ozone injection therapy is a minimally invasive treatment that has been increasingly used to relieve symptoms in people…
- Trial name
- NCT07662512
- Testing
- ozone injection
- Where
- Turkey (Türkiye)
- Volunteers
- 159 people
- Sponsor
- Sakarya University
Knee Osteoarthristis, Osteearthritis
Effects of Diagonal Proprioceptive Neuromuscular Facilitation Patterns on Pain and Functional Outcomes in Patients With Knee Osteoarthritis
A randomized controlled trial will be conducted at the Department of Physiotherapy, Dr. Ziauddin Hospital and Al-Rayaz Hospital, Karachi, Pakistan.
- Conditions
- Knee Osteoarthristis, Osteearthritis, Knee Pain Arthritis
- Trial name
- NCT07396233
- Testing
- Diagonal Proprioceptive Neuromuscular Facilitation (PNF) Pattern Exercises, Conventional Strength Training Exercises, Heat Therapy
- Where
- 2 sites in Pakistan
- Volunteers
- 150 people
- Sponsor
- University of Karachi
Knee Osteoarthristis
Efficacy and Safety of Intra-articular Injections of Frozen Platelet-Rich Plasma in Patients With Knee Osteoarthritis
Evaluation of intra-articular injections in knee osteoarthritis using frozen-stored PRP. Compared with intra-articular injections of PRP applied at the time of collection.
- Trial name
- NCT07329361
- Testing
- Platelet Rich Plasma
- Where
- Spain
- Volunteers
- 60 people
- Sponsor
- MiKS Hospital
Knee Osteoarthristis, Knee Pain Arthritis
Stimulation of Peripheral Afferents to Reduce Muscle Inhibition at the Knee
Knee osteoarthritis is a leading cause of disability, and the muscle weakness that limits walking in this population arises not only from the joint itself but from afferent signals that inhibit motor drive to the thigh muscle…
- Conditions
- Knee Osteoarthristis, Knee Pain Arthritis, Knee Pain Chronic
- Trial name
- SPARK (NCT07832669)
- Testing
- Peripheral Electrical Stimulation (PES), Paired Pulse Electrical Stimulation (ppES)
- Volunteers
- 50 people
- Sponsor
- Northeastern University
Knee Osteoarthristis, Arthroplasties, Knee Replacement
Accelerated Rehabilitation in Individuals After Total Knee Arthroplasty
The primary aim of this double-blind randomized controlled trial is to evaluate the effectiveness of an accelerated rehabilitation protocol on knee joint function and quality of life in individuals undergoing TKA compared to…
- Trial name
- NCT07319546
- Testing
- Accelerated exercise, Routine exercise
- Where
- China
- Volunteers
- 32 people
- Sponsor
- Mahidol University
Knee Osteoarthristis
Efficacy of Intra-articular Injection of Human Amniotic Suspension Allograft and Platelet-rich Plasma in the Treatment of Knee Osteoarthritis.
A double-blind, randomized controlled trial designed to evaluate the symptomatic modulating efficacy of amniotic suspension allograft (ASA) in comparison to platelet-rich plasma (PRP), hyaluronic acid (HA) and normal saline (NS)…
- Trial name
- NCT04698265
- Testing
- Human amniotic suspension allograft (ASA)
- Volunteers
- 150 people
- Sponsor
- Kaohsiung Veterans General Hospital.
Knee Osteoarthristis
Effect of a Topical Cetylated Fatty Acid Cream on Pain Relief in Patients With Knee Osteoarthritis
This multicenter, randomized, double-blind, placebo-controlled study is designed to evaluate the efficacy and safety of Cetilar® cream in adults with osteoarthritis-related knee pain.
- Trial name
- CETI-KNEE (NCT07745387)
- Testing
- Cetilar® Cream
- Where
- 4 sites in Georgia
- Volunteers
- 156 people
- Sponsor
- Pharmanutra S.p.a.
Knee Osteoarthristis
geniculaR Artery eMBolization for Knee Osteoarthritis (RAMBO) Registry
The goal of this observational study (prospective registry) is to collect long-term real-world data on the effectiveness and safety of genicular artery embolization (GAE) for knee osteoarthritis in adults aged 18 years or older…
- Trial name
- RAMBO (NCT07380906)
- Testing
- Genicular Artery Embolization
- Where
- United States
- Volunteers
- 1,200 people
- Sponsor
- Joint & Vascular Institute
Knee Osteoarthritis
Effects of Steroid, Dextrose Prolotherapy, and Platelet-Rich Plasma Injections in Knee Joint OA Patients
The novelty of thisstudy lies in its comparative assessment of three latest intra-articular injection therapies including steroid injections, dextrose prolotherapy, and PRP, for knee OA associated impairments, with a focus on…
- Trial name
- NCT07243392
- Testing
- Intra articular steroid injection, Intra articular PRP, Intra articular dextrose prolotherapy
- Where
- Pakistan
- Volunteers
- 72 people
- Sponsor
- Lincoln University College
Knee OA, Knee Osteoarthristis
TcPRF for Knee Osteoarthritis
Objectives Primary Objective: To evaluate the efficacy of transcutaneous PRF treatment in reducing knee pain compared to a sham intervention Secondary Objectives: To assess the improvement in functional outcomes and patient…
- Trial name
- NCT07351981
- Testing
- Transcutaneous Pulsed Radiofrequency (PRF) Treatment for Knee Pain
- Where
- Greece
- Volunteers
- 50 people
- Sponsor
- National and Kapodistrian University of Athens
Knee Osteoarthristis, Arthroplasty Replacement, Knee
Return to Sports After Knee Arthroplasty
The ability to return to sports after joint arthroplasty is increasingly becoming an important factor for patients in terms of their perceived quality of life.
- Trial name
- RTS (NCT07183475)
- Testing
- Return to sports test
- Where
- Germany
- Volunteers
- 50 people
- Sponsor
- Technical University of Munich
Knee Osteoarthristis
Gender Based Comparison of the Effects of Sensory Modulated Graded Weight Bearing Physiotherapy In Adults With Knee Osteoarthritis
This comparative experimental study aims to evaluate the effectiveness of Sensory-Modulated Graded Weight-Bearing Physiotherapy (SMGWBP) in patients with knee osteoarthritis and compare treatment outcomes between male and female…
- Trial name
- GSMGWBP (NCT07784998)
- Testing
- Sensory-Modulated Graded Weight-Bearing Physiotherapy
- Where
- Pakistan
- Volunteers
- 52 people
- Sponsor
- Shifa Tameer-e-Millat University
Knee Osteoarthristis
Efficacy of Virtual Reality Based Exercise Regimes on Kinesiophobia, Pain and Functional Disability in Patients With Knee Osteoarthritis
Knee Osteoarthritis is one of the most prevalent degenerative conditions in Pakistan. Although a variety of Physical therapy treatments have been proven to be beneficial in patients with early stages of knee Osteoarthritis.
- Trial name
- NCT05777421
- Testing
- Conventional Physical Therapy for Knee Osteoarthriths, Virtual Reality-Based Therapeutic Exercise regimes
- Where
- Pakistan
- Volunteers
- 24 people
- Sponsor
- Foundation University Islamabad