Clinical trials: Knee Osteoarthritis
Knee Osteoarthrosis
Use of Wharton Jelly Derived Mesenchymal Stem Cells for Knee Osteoarthrosis
Wharton Jelly derived Mesenchymal Stem Cells (WJMSC) will be injected in patients diagnosed with Knee osteoarthrosis
- Trial name
- NCT02963727
- Testing
- Wharton Jelly derived mesenchymal stem cell
- Where
- Jordan
- Volunteers
- 10 people
- Sponsor
- Hanan Jafar
Osteoarthritis, Knee, Pain, Joint
Assessment of the Effect of Spa Treatment on Rheumatological Conditions
1. Primary outcome measure: measuring the effect of spa treatment in patients suffering from lower limb osteoarthritis or any other lower limb rheumatological condition.
- Conditions
- Osteoarthritis, Knee, Pain, Joint, Lower Back Pain, Rheumatic Diseases
- Trial name
- CONTREXEVILLE (NCT03538470)
- Testing
- Spa Treatment
- Where
- 4 sites in France
- Volunteers
- 150 people
- Sponsor
- SAEML Contrexéville
Bone Diseases, Infectious, Musculoskeletal Diseases
Multi-Vendor Multi-Site Novel Accelerated MRI Relaxometry
Currently the diagnosis of OA is based on radiographs and clinical findings, which is limited to detecting late-stage disease. There is a pressing, unmet clinical need for robust assessment of early changes in cartilage health.
- Conditions
- Bone Diseases, Infectious, Musculoskeletal Diseases, Joint Diseases, Osteoarthritis
- Trial name
- MVMS_MRI (NCT04536103)
- Testing
- MRI
- Where
- United States
- Volunteers
- 88 people
- Sponsor
- Xiaojuan Li
Osteoarthritis
TKR With and Without the Use of Intra-operative Sensing
The purpose of this study is to determine if there is a difference in clinical outcomes after total knee replacement (TKR) performed with traditional ligament balancing compared to use of intraoperative sensing technology (IOS)…
- Trial name
- NCT04251442
- Testing
- OrthoSensor Verasense Technology
- Where
- United States
- Sponsor
- Hospital for Special Surgery, New York
Osteoarthritis of the Knee
LOW LOAD RESISTANCE BLOOD FLOW RESTRICTION TRAINING VERSUS NEUROMUSCULAR TRAINING IN KNEE OSTEOARTHRITIS
This study will be conducted to compare the effect of BFR with LLRT versus neuromuscular training on quadriceps muscle strength, knee joint function and proprioception accuracy.
- Trial name
- NCT04600661
- Testing
- Traditional exercise therapy
- Volunteers
- 63 people
- Sponsor
- Mai Mohamed Abdelkader Abdallah
Knee Osteoarthritis
Reliability and Validity Study of Urdu Version of Oxford Knee Score in Patients With Knee Osteoarthritis
To translate the Oxford knee score into Urdu language To evaluate the reliability and validity of Urdu Version of Oxford knee score for accessing pain and physical function in patients with knee osteoarthritis.
- Trial name
- NCT05440461
- Where
- Pakistan
- Volunteers
- 100 people
- Sponsor
- Riphah International University
Knee Osteoarthritis, Joint Diseases
Robotic Total Knee Arthroplasty Anesthesia Management
Robotic arthroplasty is increasing in acceptance on a global scale as a result of advancements in orthopedic surgery technology.
- Conditions
- Knee Osteoarthritis, Joint Diseases, Anesthesia
- Trial name
- NCT05791773
- Testing
- the robot assisted total knee arthroplasty, the conventional jig-based total knee arthroplasty
- Volunteers
- 150 people
- Sponsor
- Saglik Bilimleri Universitesi Gulhane Tip Fakultesi
Osteoarthritis, Knee
Oxford Partial Knee Comparative Instrument Pilot Study
The purpose of this prospective clinical data-collection is to document the performance and clinical outcomes of the Oxford Partial Knee System using Signature Custom Guides and Conventional Instrumentation.
- Trial name
- NCT01410786
- Testing
- Conventional Instrumentation, Signature Custom Guides
- Where
- New Zealand
- Volunteers
- 35 people
- Sponsor
- Zimmer Biomet
Gonarthrosis, Serum Albumin Low
PROGNOSTIC ROLE OF SERUM ALBUMIN LEVEL IN RADIOLOGICAL PROGRESSION OF GONARTHROSIS: IS IT A BIOMARKER IN ITSELF? A BIOMARKER ASSOCIATED WITH SYSTEMIC INFLAMMATION?
The aim of our study is to evaluate the prognostic roles of serum albumin level and systemic inflammation-related indices, including and not including serum albumin level, in the radiological progression of gonarthrosis.
- Trial name
- NCT06159751
- Testing
- serum albumin level
- Where
- Turkey (Türkiye)
- Volunteers
- 375 people, healthy volunteers welcome
- Sponsor
- Ufuk University
Knee Osteoarthritis, Hip Osteoarthritis
The Kaia Hip and Knee Pain Intervention for Self-management of the Pain in Patients With Osteoarthritis.
The study intervention provides an innovative way of making exercise training and other recommended lifestyle modifications as accessible as possible for knee and hip OA participants by introducing a home-based exercise training…
- Trial name
- PIVOT (NCT04615377)
- Testing
- Kaia hip and knee pain application, Treatment as usual
- Where
- United States
- Volunteers
- 192 people
- Sponsor
- Kaia Health Software
Osteoarthritis of the Hip
Physical Therapy Prior to Total Knee Replacement
In this study, the investigators are investigating the effects of physical therapy (PT) for treating high grade knee osteoarthritis (OA) in patients that are candidates for total knee replacement.
- Trial name
- NCT02279277
- Testing
- Supervised physical therapy program prior to total knee replacement surgery
- Volunteers
- 148 people
- Sponsor
- Rothman Institute Orthopaedics
Osteo Arthritis of the Knees
Effect of Interventions on the Progression of Knee Osteoarthritis
There has been intensive search for a substance that can have disease-modifying activity for osteoarthritis. A number of medications have been reported to be of benefit on slowing progression of knee OA.
- Trial name
- KAPS (NCT02178137)
- Testing
- Diacerien, Glucosamine/Chondroitin
- Where
- Pakistan
- Volunteers
- 322 people
- Sponsor
- Indus Hospital and Health Network
Knee Osteoarthritis (Mild to Moderate, Medial Compartment)
Enhancing Medial Knee Pain Rehabilitation : A Clinical Trial On The Effectiveness Of Blood Flow Restriction In Combination With Targeted Exercises For Adult With Varus Deformity
Medial knee pain is common in active adults with varus knee alignment and can limit daily and sports activities. Standard physiotherapy can reduce pain and improve function, but strength gains may be suboptimal when patients…
- Trial name
- NCT07283237
- Testing
- Targeted Exercise Program, Blood Flow Restriction (BFR) Training with Targeted Exercise Program
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Assiut University
Osteoarthritis, Knee
The Inclination of the Proximal Tibiofibular Joint Surface and Medial Compartment Knee Osteoarthritis
This study aims to research on the association between the inclination of the proximal tibiofibular joint surface and medial compartment knee osteoarthritis.
- Trial name
- NCT03147495
- Testing
- Standing anteroposterior knee radiographs and special proximal tibiofibular joint radiograph.
- Where
- China
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- 113th Hospital of Chinese People's Liberation Army
Inflammation, Osteoarthritis
Photobiomodulation Therapy in Patients Receiving Total Knee Arthroplasty
Photobiomdoulation is the use of near-infrared light to relieve pain, stimulate healing and reduce inflammation. Swelling and inflammation is a common condition after orthopedics surgeries over extremity and spine.
- Conditions
- Inflammation, Osteoarthritis, Post Operative Pain
- Trial name
- NCT06426251
- Testing
- Photobiomodulation
- Where
- Taiwan
- Volunteers
- 15 people
- Sponsor
- National Taiwan University Hospital Hsin-Chu Branch
Osteoarthritis (OA) of the Knee
Impact of Blood-Flow-Restriction Prehabilitation on Pre- and Postoperative Rehabilitation After Total Knee Arthroplasty
Degenerative and traumatic diseases of the musculoskeletal system lead to increased immobility of a patient, which in turn results in muscle atrophy.
- Trial name
- NCT06964022
- Testing
- BFR
- Where
- Germany
- Volunteers
- 19 people
- Sponsor
- University Hospital, Bonn
Osteoarthritis of the Knees
Determining the Optimal Dose of AD-211 in Patients With Osteoarthritis of the Knee
The purpose of this study is to determine the optimal dose of AD-211 in patients with osteoarthritis of the knee.
- Trial name
- NCT07550231
- Testing
- AD-211-L, AD-211-M, AD-211-H
- Volunteers
- 200 people
- Sponsor
- Addpharma Inc.
Osteoarthritis, Knee
JOURNEY™ II CR Total Knee System
The purpose of this study is to evaluate the safety and effectiveness of the JOURNEY™ II CR Total Knee System in subjects with degenerative joint disease (DJD) requiring primary total knee replacement.
- Trial name
- NCT02440672
- Testing
- JOURNEY™ II CR Total Knee System (J II CR TKS)
- Where
- 9 sites in United States, Spain and 1 more
- Volunteers
- 170 people, healthy volunteers welcome
- Sponsor
- Smith & Nephew, Inc.
Mild to Moderate Acne, Stiffness of Joint, Nec, Involving Ankle and Foot in MDR24_1
A Proof of Science, Dose-Response Study to Evaluate the Safety, Efficacy of Different Dosages of Test Treatments
A proof of science clinical study with randomized, four-arm, comparative, single-blind, within the arm - Dose-Response Study to evaluate the safety and efficacy of different collagen peptide-containing test treatments in adult…
- Conditions
- Mild to Moderate Acne, Stiffness of Joint, Nec, Involving Ankle and Foot in MDR24_1, Other Specified Diseases of Hair and Hair Follicles, Brittle Nails
- Trial name
- NCT05613660
- Testing
- Veg Collagen Peptide, Bovine Collagen Peptide, Fish | Marine Collagen Peptide
- Where
- India
- Volunteers
- 264 people
- Sponsor
- NovoBliss Research Pvt Ltd
Knee Osteoarthritis, Knee Arthritis
Maximal Rate of Force Development of Ankle Muscles and Functional Ability in Patients With Knee Osteoarthritis
This study is a detailed assessment of the maximal rate of force development of ankle muscles and its association with functional ability in patients with knee osteoarthritis (OA).
- Trial name
- NCT06063889
- Testing
- Maximal Rate of Force Development Test for Ankle Muscles
- Where
- Egypt
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Ahram Canadian University
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