Clinical trials: Knee Osteoarthritis
Knee Osteoarthritis (Knee OA)
High-Intensity Laser Therapy (HILT) in Patients With Knee Osteoarthritis
This randomized placebo-controlled trial aims to evaluate the effectiveness of High-Intensity Laser Therapy (HILT) as an adjunct to standard outpatient physiotherapy in patients with knee osteoarthritis.
- Trial name
- NCT07661407
- Testing
- Conventional Physiotherapy, High-Intensity Laser Therapy (HILT)
- Volunteers
- 72 people
- Sponsor
- University of Rzeszow
Osteoarthritis, Chronic Pain
Mindfulness for Osteoarthritis-related Knee Pain
The purpose of this project is to investigate the feasibility and acceptability of a Mindfulness based intervention for people who are attending secondary care with Osteoarthritis (OA)-related knee pain.
- Trial name
- NCT02595099
- Testing
- Mindfulness training
- Volunteers
- 15 people
- Sponsor
- University of Nottingham
Knee Osteoarthritis
Metformin as Adjuvant Therapy in Obese Knee Osteoarthritis Patients
This study aims to evaluate the possible efficacy and safety of addition of metformin to celecoxib in patients with knee osteoarthritis.
- Trial name
- NCT05638893
- Testing
- Metformin Hcl 500Mg Tab
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Tanta University
Osteoarthritis, Knee, Osteoarthritis Knees Both
Astaxanthin for Management of Inflammation in Knee Osteoarthritis
Over 30 million Americans are currently affected by osteoarthritis (OA), with prevalence expected to increase 40% by 2025 as a result of the aging population and obesity epidemic.
- Conditions
- Osteoarthritis, Knee, Osteoarthritis Knees Both, Joint Inflammation
- Trial name
- NCT05138549
- Testing
- Astaxanthin
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Prisma Health-Midlands
Osteoarthritis, Knee
Safety and Feasibility of Umbilical Cord Wharton's Jelly Allograft Injections for Knee Osteoarthritis
This is a Pilot Study which is randomized, prospective, open label, dose escalation, non-controlled evaluating safety and feasibility of intra-articular Wharton's Jelly (WJ) allograft will be evaluated in patients suffering with…
- Trial name
- NCT06608134
- Testing
- Umbilical Cord Wharton's Jelly Allograft Intra-articular Knee Injection
- Where
- 5 sites in United States
- Volunteers
- 120 people
- Sponsor
- R3 Medical Research
Osteoarthritis of Knee
Robot-Aided Off-Axis Neuromuscular Training for Knee OA
Although the primary knee motion occurs in flexion/extension, the frontal and transverse (off-axis) knee motions are smaller but crucial for maintaining joint stability and normal knee loading.
- Trial name
- NCT07014098
- Testing
- Robot-Aided Off-Axis Neuromuscular Training, Traditional elliptical regular stepping
- Volunteers
- 36 people
- Sponsor
- University of Maryland, Baltimore
Osteoarthritis of Knee
The Recovery Time of Quadriceps Strength After Total Knee Arthroplasty (TKA): The Effect of Quadriceps Incision Length
Minimally invasive total knee arthroplasty (MIS-TKA) became the popular technique. It had the less postoperative pain and shorter recovery time compared to the conventional technique.
- Trial name
- NCT01450904
- Testing
- Quadriceps incision < 2 cm, Quadriceps incision 2-4 cm, Quadriceps incision > 4 cm
- Volunteers
- 60 people
- Sponsor
- Mahidol University
Knee Osteoarthritis
AposTherapy for Singaporean Patients With Knee Osteoarthritis (OA)
Osteoarthritis (OA) is the most prevalent form of arthritis in the elderly. It is estimated that 7% of men and 11% of women over the age of 65 have KOA.
- Trial name
- NCT01562652
- Testing
- AposTherapy (All Phases of Step-cycle {APOS} system, APOS-Medical and Sports Technologies Ltd. Herzliya, Israel)
- Where
- Singapore
- Volunteers
- 60 people
- Sponsor
- Apos Medical and Sports Technology Ltd.
Osteoarthritis
An Investigation of ReNu™ Knee Injection in Patients With Osteoarthritis
This is a Prospective, Randomized study evaluating the efficacy of ReNu for the treatment of Kellgren-Lawrence grade 2 or 3 osteoarthritis.
- Trial name
- NCT02318511
- Testing
- Knee injection, ReNu amniotic allograft, Hyaluronic Acid
- Where
- 12 sites in United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- NuTech Medical, Inc
Unilateral Primary Osteoarthritis of Knee
Bone Mineral Density Changes Under Two Tibial Components in Total Knee Arthroplasty
Osteoarthritis is a progressive disease afflicting to two thirds of Americans. Today, an estimated 43 million individuals have arthritis. By 2020, more than 59.4 million Americans will be affected by the disease.
- Trial name
- NCT01764984
- Testing
- Total knee arthroplasty
- Where
- 3 sites in Canada
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- CHU de Quebec-Universite Laval
Knee Osteoarthritis
Cemented vs Cementless TKA
The purpose of this study is to compare cemented and cementless versions of the Triathlon total knee arthroplasty/replacement (TKA) in terms of clinical outcomes, perioperative course, and outcome scores including function and…
- Trial name
- NCT03683992
- Testing
- Triathlon total knee system
- Where
- United States
- Volunteers
- 147 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Synovitis of Knee, Osteoarthritis, Knee
The Role of Synovitis in Osteoarthritis
To determine whether platelet-rich-plasma (PRP) or HA (hyaluronic acid)injection into synovitis in osteoarthritis(OA) knee can achieve improvement in knee function and reduce synovitis.
- Trial name
- NCT03167333
- Testing
- platelet rich plasma, Hyaluronic acid
- Where
- Taiwan
- Volunteers
- 100 people
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Anxiety, Pain
The Effect of Aromatherapy on Anxiety in Patients
Preoperative anxiety is considered a potential and preventable risk factor for postoperative complications.
- Trial name
- NCT05500664
- Testing
- Lavender Oil
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Assiut University
Severity of OA Knee, Difference of Joint Space Width Between One-leg and Both-leg Standing Radiograph
One-Leg Standing Radiograph: A Novel Technique to Evaluate the Severity of OA Knee
The purpose of this study is assess the severity of osteoarthritic knee between one-leg and both-leg standing radiograph in primary OA knee
- Trial name
- OA knee (NCT02051699)
- Testing
- radiographic of standing knee
- Where
- Thailand
- Volunteers
- 50 people
- Sponsor
- Thammasat University
Knee Osteoarthritis, Hip Osteoarthritis
Comparison of Knotless Barbed Suture and Standard Suture in Knee Replacement Patients
Barbed suture use has been gaining increased acceptance and has been reported to offer potential advantages in wound closure of hip and knee replacement surgeries.
- Trial name
- NCT03031314
- Testing
- barbed suture, standard suture
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Washington Hospital Healthcare System
Osteoarthritis, Knee, Postoperative Edema
Effect of Tergase Injection on Reducing Edema After Bilateral Total Knee Arthroplasty
This clinical trial is conducted to compare and evaluate the efficacy and safety of Tergase injection (4,500 IU) in reducing postoperative edema between treated and untreated knees in patients undergoing bilateral total knee…
- Conditions
- Osteoarthritis, Knee, Postoperative Edema, Bilateral Total Knee Arthroplasty
- Trial name
- ALT-TKA (NCT07705165)
- Testing
- Berahyaluronidase alfa
- Volunteers
- 30 people
- Sponsor
- Man Soo Kim
Osteoarthritis
Do We Need Computer Assistance To Improve the Survival of Primary Total Knee Arthroplasty. A Minimum Ten Years Follow-up
The investigators asked: (1) Do computer-assisted total knee arthroplasty (TKAs) provide better alignment and clinical function? (2) Do computer-assisted TKAs provide better survivorship of implants and less complication? and (3)…
- Trial name
- NCT01520571
- Testing
- Non-Computer Assistance TKA, Computer Assistance TKA
- Where
- South Korea
- Volunteers
- 520 people
- Sponsor
- Ewha Womans University
Arthritis, Osteoarthritis
Tanezumab In Osteoarthritis Of The Knee (2)
The purpose of this study is to test the efficacy and safety of 2 doses of tanezumab compared with naproxen and placebo in patients with osteoarthritis.
- Trial name
- NCT00830063
- Testing
- tanezumab 10 mg, tanezumab 5 mg, naproxen
- Where
- 94 sites in United States
- Volunteers
- 832 people
- Sponsor
- Pfizer
Osteoarthritis Knees Both
Efficacy of Corticosteroid and Local Anesthetic Injections Patients With Concomitant Pes Anserine Bursitis
To evaluate the efficiencies of local corticosteroid injections and local anesthetics in patients with concomitant pes anserine bursitis and osteoarthritis.
- Trial name
- NCT04887844
- Testing
- Lidocaine injection, Corticosteroid injection, Conventional Physical therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 102 people
- Sponsor
- Abant Izzet Baysal University
ACL Injury, Knee Osteoarthritis
The Efficiency and Safety of PRP Treatment After Anterior Cruciate Ligament Reconstruction.
The anterior cruciate ligament (ACL) is the main stabilizer of the knee joint, as it controls anteroposterior and rotatory knee laxity.
- Conditions
- ACL Injury, Knee Osteoarthritis, Knee Injuries
- Trial name
- NCT06442319
- Testing
- Platelet-rich plasma
- Where
- Poland
- Volunteers
- 60 people
- Sponsor
- Nicolaus Copernicus University in Toruń, Collegium Medicum in Bydgoszcz
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.