Clinical trials: Knee Osteoarthritis
Knee Osteoarthritis (OA), Postoperative Pain
Effect of Adding a Biceps Femoris Short Head Block to Adductor Canal Block for Analgesia After Total Knee Arthroplasty
Total knee arthroplasty (TKA) is frequently associated with moderate to severe postoperative pain, which may delay mobilization, increase opioid consumption, and impair functional recovery.
- Trial name
- BiFeS-TKA (NCT07803887)
- Testing
- Ultrasound-Guided Adductor Canal Block, Ultrasound-Guided Biceps Femoris Short Head Block
- Where
- Turkey (Türkiye)
- Volunteers
- 122 people
- Sponsor
- Antalya Training and Research Hospital
Osteoarthritis, Knee
Determination of the Effectiveness of Certain Physical Methods in the Treatment of Knee Osteoarthritis
Osteoarthritis (OA) is a chronic joint disease that involves the entire joint, causing cartilage damage, bone remodeling, osteophyte formation and loss of normal joint function.
- Trial name
- BFBOA (NCT04197284)
- Testing
- Biofeedback, Myomed 632, device for electrical stimulation, BTL 4000 Smart, kinesitherapy
- Where
- Croatia
- Volunteers
- 93 people
- Sponsor
- Clinical Hospital Centre Zagreb
Osteoarthritis
JOINTS Study - Joint Replacement Outcome in Inpatient Rehabilitation Facilities and Nursing Treatment Sites
1. What are the characteristics of joint replacement patients (DRGs 209 \& 210) served in IRFs and SNFs? How are they similar or different? 2.
- Trial name
- JOINTS (NCT00499278)
- Testing
- Rehabilitation after joint replacement surgery
- Where
- United States
- Volunteers
- 2,384 people
- Sponsor
- MedStar National Rehabilitation Network
Osteoarthritis
Adductor Canal Block Versus Periarticular Bupivicaine Injection in Total Knee Arthroplasty
The objective of the study is to compare the efficacy of adductor canal blocks versus periarticular bupivacaine injections for pain management in total knee arthroplasty.
- Trial name
- NCT02777749
- Testing
- Bupivacaine
- Where
- United States
- Volunteers
- 155 people
- Sponsor
- Columbia University
Osteoarthritis
Time-dependent Improvement of Functional Outcome Following Oxford Medial Unicondylar Knee Replacement
The objective of this prospective study is to determine (1) the time course of patient-relevant functional outcome evaluated by the Knee injury and Osteoarthritis Outcome Score (KOOS) and (2) the time course of range of motion…
- Trial name
- NCT01032538
- Where
- 3 sites in Norway
- Volunteers
- 99 people
- Sponsor
- Vestre Viken Hospital Trust
Falls, Total Knee Arthroplasty (TKA)
Risk of Falling After CFNB Versus ACB
Blocking sensation from the femoral nerve by injecting local anesthetic around the nerve plays an important role in pain control after total knee replacement.
- Conditions
- Falls, Total Knee Arthroplasty (TKA), Osteoarthritis
- Trial name
- NCT02314832
- Testing
- adductor canal block, femoral nerve block
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- University of Pennsylvania
Knee Osteoarthritis, Fall
Community-based Rehabilitation and Fall Prevention Program After Total Knee Arthroplasty
Knee osteoarthritis (OA) is a common musculoskeletal disorder among older people. Since the prevalence of knee OA increases with age, it is anticipated that the prevalence and burden of knee OA will increase significantly given…
- Trial name
- NCT03615638
- Testing
- Fall prevention program
- Where
- 2 sites in Hong Kong
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Knee Injuries, Knee Osteoarthritis
Blood-Flow Restriction Exercise Following a Knee Replacement
This study will determine the safety and efficacy of using blood-flow restriction exercise enhancement (B-FREE) to overcome persistent quadriceps muscle weakness that occurs following a total knee replacement (TKR).
- Conditions
- Knee Injuries, Knee Osteoarthritis, Knee Arthritis
- Trial name
- NCT04018638
- Testing
- B-FREE
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Michigan Technological University
Knee Osteoarthritis, Knee Osteoarthritis (Knee OA)
Genicular Artery Embolization for Reducing Pain in Medically Refractory Symptomatic Knee Osteoarthritis
Genicular Artery Embolization for Reducing Pain in Symptomatic Knee Osteoarthritis: A Pilot Randomized Sham-Controlled Study (SHAM-PAIN) is a NIH-NIAMS funded project designed to assess enrollment feasibility and detect any…
- Conditions
- Knee Osteoarthritis, Knee Osteoarthritis (Knee OA), Knee Osteoarthritis (OA)
- Trial name
- SHAM-PAIN (NCT06859164)
- Testing
- Genicular Artery Embolization, Lipiodol, Simple angiogram
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Utah
Knee Osteoarthritis
Footwear and Exercise for Knee Osteoarthritis (FiREwORK Trial)
Osteoarthritis (OA) is a chronic degenerative joint disease and leading cause of musculoskeletal pain and disability worldwide. The high rates of knee replacement surgery worldwide emphasize the need for more effective…
- Trial name
- FiREwORK (NCT03796832)
- Testing
- Flat Flexible Shoes, Stable Supportive Shoes, Exercise Therapy
- Where
- Belgium
- Volunteers
- 97 people
- Sponsor
- University Ghent
Sedentary Lifestyle, Knee Osteoarthritis
NEAT!2 Sedentary Behavior Reduction for Individuals With Past or Present Knee Symptoms, Injuries, or Surgeries
This study will evaluate the effectiveness of an mHealth sedentary reduction program over a 6-month period of time in adults with past or present knee symptoms, injuries, or surgeries.
- Conditions
- Sedentary Lifestyle, Knee Osteoarthritis, Knee Injuries, Knee Pain Chronic
- Trial name
- NCT03987932
- Testing
- NEAT!2, NEAT!2+Calls, Delayed NEAT!2
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- University of South Carolina
Knee Osteoarthritis
Effects of Low-Load Blood Flow Restriction Resistance Training With and Without Hip Abductor Strengthening in Patients With Knee Osteoarthritis.(BFR)
This study aims to compare the effects of low-load Blood Flow Restriction (BFR) resistance training with and without hip abductor strengthening in patients with knee osteoarthritis.
- Trial name
- yes (NCT07892144)
- Testing
- Hip Abductor Strength Training followed by Low-Load BFR Resistance Training, Low-Load Blood Flow Restriction (BFR) Resistance Training
- Where
- Pakistan
- Volunteers
- 44 people
- Sponsor
- University of Management and Technology Lahore
Osteoarthritis
A Study to Determine the Difference in Low Contact Stress (LCS) Duofix Versus Low LCS Porocoat Knee Systems
The primary objective of this investigation is to test the hypothesis that the Duofix Tibial component results in a reduction of immediate postoperative pain compared to the LCS Porocoat version.
- Trial name
- NCT00733499
- Testing
- LCS Complete Duofix, LCS Complete Porocoat
- Where
- Ireland
- Volunteers
- 206 people
- Sponsor
- DePuy International
Bilateral Knee Osteoarthritis, Autologous Adipose Tissue
Bilateral Knee Osteoarthritis: Intra-articular Injection of Filtered Autologous Adipose Tissue Versus Placebo
The purpose of the study is to assess the radiological and clinical outcomes comparing two different treatments (Filtered Autologous Adipose Tissue versus Placebo) in patients affecting bilateral knee osteoarthritis.
- Trial name
- NCT04567732
- Testing
- injection of Filtered Autologous Adipose Tissue
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- Istituto Ortopedico Rizzoli
Knee Osteoarthritis
Total Knee Arthroplasty: Functional and Clinical Outcomes
The purpose of this study is to assess the differences in functional and patient reported outcomes between total knee replacement (TKA) implants.
- Trial name
- NCT01811563
- Testing
- Zimmer, Stryker
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Duke University
Osteoarthritis, TKA
Comparing Articular Noise and Its Perception Between Two Different Types of Individualized Total Knee Arthroplasty
Knee osteoarthritis is a degenerative joint disorder leading to pain and limited movement. Total knee arthroplasty (TKA) has transformed the treatment of knee osteoarthritis, resulting in long-term outcomes that enhance the…
- Trial name
- ANIKA (NCT07030049)
- Testing
- Postero-stabilized total knee replacement for knee osteoarthritis, Cruciate-retaining total knee replacement for knee osteoarthritis
- Volunteers
- 210 people
- Sponsor
- Clinique Trenel
Knee Osteoarthritis
Treatment of Knee Osteoarthritis With Bone Marrow Aspirate Matrix: Prospective, Randomized Trial
Knee osteoarthritis (KOA) first manifests itself as a molecular derangement followed by anatomical and/or physiological changes. Conservative treatment of osteoarthritis should be the first approach to patients with this disease.
- Trial name
- NCT06238934
- Testing
- Bone marrow aspirate matrix, Bone marrow aspirate, Hyaluronic acid
- Where
- Brazil
- Volunteers
- 90 people
- Sponsor
- Instituto Nacional de Traumatologia e Ortopedia
Knee Osteoarthritis, Laser Therapy
Evaluation of the Effect of High-intensity Laser Therapy in Knee Osteoarthritis
The aim of this study is to evaluate the effects of high intensity laser therapy (HILT) on range of motion, pain, quality of life, muscle strength and femoral cartilage thickness in patients with knee osteoarthritis.
- Conditions
- Knee Osteoarthritis, Laser Therapy, Muscle Strength
- Trial name
- NCT05510648
- Testing
- high-intensity laser therapy
- Volunteers
- 60 people
- Sponsor
- Necmettin Erbakan University
Osteoarthritis, Hip, Osteoarthritis, Knee
Spinal Anaesthesia vs. General Anaesthesia for THA, TKA and UKA
The goal of this randomized clinical trial is to investigate the postoperative recovery following hip and knee arthroplasty procedures depending on the use of either spinal anaesthesia (SA) or general anaesthesia (GA).
- Trial name
- RCT SAGA (NCT05706844)
- Testing
- Spinal anesthesia, General anaesthesia
- Where
- 2 sites in Denmark
- Volunteers
- 222 people
- Sponsor
- Anders Troelsen
Knee Osteoarthritis
Effectiveness of Muscle Energy Techniques and Mulligan Mobilization Along With Conventional Physical Therapy in Knee Joint Osteoarthritis Patients
This study aims to evaluate the effectiveness of integrating Muscle Energy Technique (MET) and Mulligan Mobilization with conventional physical therapy in the management of knee osteoarthritis (OA), with a specific focus on…
- Trial name
- NCT06954363
- Testing
- Mulligan Mobilization, Muscle Energy Technique (MET)
- Where
- 3 sites in Pakistan
- Volunteers
- 24 people
- Sponsor
- Khyber Medical University Peshawar
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