Clinical trials: Knee Osteoarthritis
Baker Cyst, Fenestration
"The Importance of Adding Fenestration to Ultrasound-Guided Baker's Cyst Aspiration"
This study aims to evaluate whether adding a fenestration procedure to standard ultrasound-guided aspiration and corticosteroid-lidocaine injection provides additional clinical benefits for patients with symptomatic Baker's cyst…
- Conditions
- Baker Cyst, Fenestration, Musculoskeletal Ultrasound, Steroid Injection
- Trial name
- NCT07385560
- Testing
- Baker's Cyst Aspiration, Steroid-Lidocaine Injection, Ultrasound-Guided Fenestration
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people
- Sponsor
- Istanbul University - Cerrahpasa
Osteoarthritis, Knee
Comparing Manipulation, Rehabilitation and Combination of the Two in the Treatment of Knee Osteoarthritis
Common medical therapies for knee osteoarthritis are patient education, drug and physical therapy, exercise and surgery. These modalities may offer improvement but drugs and surgery carry significant risk.
- Trial name
- NCT01188837
- Testing
- Full Kinetic Chain Manipulative Therapy, Full Kinetic Chain Rehabilitation, Full Kinetic Chain Manipulative Therapy with Rehabilitation
- Where
- 2 sites in United States, South Africa
- Volunteers
- 144 people
- Sponsor
- Cleveland Chiropractic College
Osteoarthritis of the Knee
Targeted Rehabilitation to Improve Outcome After Knee Replacement- A Physiotherapy Study
The TRIO-physio study is looking at how well patients with osteoarthritis recover after knee replacement surgery (also known as Total Knee Arthroplasty (TKA)). Currently around 20% of patients are not satisfied after TKA.
- Trial name
- TRIO-Physio (NCT01849445)
- Testing
- Intensive physiotherapy, Home physiotherapy exercises
- Where
- 6 sites in United Kingdom
- Volunteers
- 334 people
- Sponsor
- University of Edinburgh
Osteoarthritis, Knee, Arthroplasty
Comparison of Three Knee Replacements
The present randomized controlled trial is designed to compare one novel total knee replacement (TKR) design and two conventional TKR designs in terms of functional outcome.
- Conditions
- Osteoarthritis, Knee, Arthroplasty, Total Knee Replacement
- Trial name
- NCT03339557
- Testing
- NexGen, Persona, PFC
- Where
- Finland
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Coxa, Hospital for Joint Replacement
Knee Osteoarthritis
Comparison of the Efficacy of Phenol Block and Corticosteroid-Local Anesthetic Block Applied to the Genicular Nerve
There are different neurolysis methods. Aim of this study is to compare two different methods, phenol block and corticosteroid local anesthetic block.
- Trial name
- NCT06265675
- Testing
- Phenol, Celestone, Lidocain
- Where
- Turkey (Türkiye)
- Volunteers
- 88 people
- Sponsor
- Gaziler Physical Medicine and Rehabilitation Education and Research Hospital
Osteoarthritis, Hip, Osteo Arthritis Knee
Health Coaching for Patients Waiting for Hip or Knee Replacements
A randomised controlled feasibility study of a health coaching intervention targeting people on the waitlist for hip or knee replacement surgery with low patient activation.
- Trial name
- NCT06101875
- Testing
- Health Coach (Health coaching), Digital Toolkit (Control)
- Where
- United Kingdom
- Volunteers
- 50 people
- Sponsor
- Sheffield Hallam University
Meniscus Injury, Knee Osteoarthritis
Knee Arthroscopy Cohort Southern Denmark (KACS)
PURPOSE: To investigate the natural time course of patient-reported outcomes after meniscus surgery and identify factors associated with good and bad outcome after surgery.
- Trial name
- KACS (NCT01871272)
- Testing
- Arthroscopic Meniscus Surgery
- Where
- 4 sites in Denmark
- Volunteers
- 491 people
- Sponsor
- University of Southern Denmark
Knee Osteoarthritis, Sarcopenia
The Effects of Pulsed Electromagnetic Field Therapy on Patients With End-stage of Knee Osteoarthritis
A double-blinded, randomizepd controlled trial to investigate the treatment effects of pulsed electromagnetic field (PEMF) on end stage of knee osteoarthritis patients with sarcopenia will be carried out.
- Trial name
- NCT05550428
- Testing
- home-based-exercise, active pulsed electromagnetic field（PEMF）therapy
- Where
- Hong Kong
- Volunteers
- 60 people
- Sponsor
- Chinese University of Hong Kong
Hip Osteoarthritis, Knee Osteoarthritis
Hip and Knee Scores
Patient-reported outcome measures (PROMs) are currently used for evaluating orthopaedic procedures. Nevertheless, there is no consensus in the different studies, making them difficult to compare .
- Trial name
- HIP-KNEE (NCT04057651)
- Where
- France
- Volunteers
- 800 people
- Sponsor
- University Hospital, Lille
OSTEOARTHRITIS OF THE KNEE
Analgesic Effects of a Treatment With Cannabis Sativa Extract in Patients With Knee Osteoarthritis - CANOA (Cannabis for Osteoarthritis)
Osteoarthritis (OA) is the most prevalent joint disease in humans, often causing disability in affected individuals, especially the elderly.
- Trial name
- NCT06588972
- Testing
- Medium Chain Triglyceride solution, Cannabis Sativa
- Where
- Brazil
- Volunteers
- 45 people
- Sponsor
- Federal University of Latin American Integration
Obesity, Osteoarthritis
Surgical Weight-Loss to Improve Functional Status Trajectories Following Total Knee Arthroplasty (SWIFT Trial)
The purpose of the SWIFT Trial is to answer two research questions. 1. Does bariatric surgery before total knee arthroplasty (TKA) improve both perioperative and long-term outcomes of TKA in extreme obesity? 2.
- Trial name
- SWIFT (NCT02598531)
- Where
- United States
- Volunteers
- 289 people
- Sponsor
- Geisinger Clinic
Knee Arthritis, Osteoarthritis
Daily Knee Sleeve Use Versus No Use in Older Adults With Chronic Knee Pain
The purpose of this superiority randomized controlled trial is to evaluate the effect of daily knee sleeve use on 5-year radiographic knee osteoarthritis progression and knee-related symptoms in older adults with chronic knee…
- Trial name
- NCT07674901
- Testing
- Knee sleeve
- Where
- United States
- Volunteers
- 235 people
- Sponsor
- Margaret L Gourlay, MD, MPH
Osteoarthritis, Knee
Warm Needle Acupuncture vs Needle Acupuncture
This is a two-armed randomised controlled pilot study that investigates the component efficacy of moxibustion for osteoarthritis of the knee.
- Trial name
- NCT02680912
- Testing
- Warm needle acupuncture, Needle acupuncture
- Where
- United Kingdom
- Volunteers
- 14 people
- Sponsor
- London South Bank University
Osteoarthritis
Minimally Invasive Total Knee Replacement - Navigated Versus Non-navigated Study
The primary objective of this investigation is to compare the precision of long leg alignment achieved by the two types of procedure.
- Trial name
- NCT00733330
- Testing
- Either P.F.C. Sigma or L.C.S. Complete knee replacement using the conventional surgical approach and manual surgical technique, Either P.F.C. Sigma or L.C.S. Complete knee replacement using minimally invasive surgical approach and computer navigation
- Where
- 5 sites in United States, Australia and 1 more
- Volunteers
- 86 people
- Sponsor
- DePuy International
Knee Osteoarthristis
Feasibility of a Self-management App for People With Knee Osteoarthritis (OA-AID Feasibility Study)
In this feasibility trial, an 8-week digital intervention including remote monitoring in patients with knee osteoarthritis (OA) will be tested.
- Trial name
- NCT06656845
- Testing
- Genus, a self-management app for patients with knee osteoarthritis
- Where
- Norway
- Volunteers
- 20 people
- Sponsor
- Diakonhjemmet Hospital
Knee Pain, Osteoarthritis
The Effects of the Electro, Heat and Cold -Therapy During Physiotherapy Treatment in Osteoarthritis(OA) of KNEE
The objective of this clinical trial is to evaluate the pain relief and daily functioning improve, in patients suffering of Osteoarthritis of knee, with HOT/COLD/ Electro therapy during physiotherapy treatment
- Trial name
- NCT01112319
- Testing
- Elf care, control group
- Where
- Israel
- Sponsor
- Meir Medical Center
Knee Osteoarthritis, Knee Osteoarthritis (Knee OA)
Efficacy of Platelet-Rich Plasma Combined With Hyaluronic Acid in Knee Osteoarthritis
This prospective, randomized, open-label, single-centre post-market clinical follow-up (PMCF) study evaluates the clinical performance and safety of a single intra-articular injection of hyaluronic acid (HA) combined with…
- Conditions
- Knee Osteoarthritis, Knee Osteoarthritis (Knee OA), Knee Osteoarthritis (OA), Osteoarthritis (OA) of the Knee
- Trial name
- NCT07784907
- Testing
- Hyaluronic Acid (HA) and Platelet rich plasma (PRP), Hyaluronic Acid (HA)
- Where
- Poland
- Volunteers
- 100 people
- Sponsor
- Implai Sp z o.o
Osteoarthritis
Clinical Trial of Allogenic Adipose Tissue-Derived Mesenchymal Progenitor Cells Therapy for Knee Osteoarthritis
Evaluate the safety and efficacy of Allogenic Adipose Tissue-Derived Mesenchymal Progenitor Cells Therapy for Knee Osteoarthritis.
- Trial name
- NCT02641860
- Testing
- Mesenchymal progenitor cells
- Where
- China
- Volunteers
- 22 people
- Sponsor
- Shanghai AbelZeta Ltd.
Knee Osteoarthritis
The Effectiveness of Ultrasound Guided Ozone (O2-O3) Injection With Knee Osteoarthritis
Knee ostheoarthritis (KOA) is a common disabling and degenerative disease leading to painful joints, articular stiffness, and decreased function.
- Trial name
- NCT04830423
- Testing
- Medical ozone injection, steroid injection group
- Where
- Turkey (Türkiye)
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Gaziler Physical Medicine and Rehabilitation Education and Research Hospital
Osteoarthritis, Osteo Arthritis Knee
An Study to Evaluate Safety and Tolerability of OA-SYS in Subjects With Moderate to Severe Osteoarthritis of the Knee Joint
This study is being conducted to evaluate the safety and tolerability of OA-SYS in patients with moderate to severe OA of the knee joint.
- Trial name
- OA-SYS-01 (NCT06485843)
- Testing
- OA-SYS
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- Ageless Biotech, Inc.
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.