Clinical trials: Knee Pain Chronic
Knee Osteoarthritis, Knee Pain Chronic
Evaluation of NMES for Reducing Pain and Improving Functional Outcomes in Knee OA Patients
The present prospective trial is designed to evaluate the efficacy of CyMedica Orthopedics e-vive™ system, a multifunctional electrotherapy device providing neuromuscular electrical stimulation (NMES) for reducing pain and…
- Conditions
- Knee Osteoarthritis, Knee Pain Chronic, Knee Arthritis
- Trial name
- NMES (NCT03980964)
- Testing
- Active NMES
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- CyMedica Orthopedics, Inc
Osteo Arthritis Knee, Pain, Chronic
Study of the Effects of Photobiomodulation in Patients With Osteoarthritis
PhotoBioModulation (PBM) is a mature science with therapeutic efficacy in humans and animals, and with excellent results in different medical specialties without side effects.
- Conditions
- Osteo Arthritis Knee, Pain, Chronic, Inflammation
- Trial name
- NCT03924128
- Testing
- Photobiomodulation
- Where
- Brazil
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Chronic Pain, Osteoarthritis, Knee
Generate and Test the Reliability of a PD Model of OXT on Pupillary Hippus as a Measure of CNS Activity
The purpose of this research is to evaluate the effects of oxytocin (naturally occurring hormone) given by an intramuscular (IM; into the muscle) injection, has on your parasympathetic nervous system.
- Trial name
- NCT04427709
- Testing
- Oxytocin
- Where
- United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Chronic Low-back Pain
Muscle Energy Technique and Foam Roller Self Myofascial Release in Two-wheeler Riders With Chronic Low Back Pain
Pain in the lower back is a major concern in today's era due to prolonged sitting in two-wheeler riders, mainly due to hamstring tightness. It also creates physical disability and impairment in activities of daily living.
- Trial name
- NCT06017804
- Testing
- Muscle energy technique, Self-myofascial release technique
- Where
- Saudi Arabia
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- King Saud University
Inflammation, Knee Pain Chronic
Effects of UC-II, Glucosamine and Curcumin Supplementation on Knee Pain and Inflammation.
This research evaluated the effects of UCII, glucosamine and curcumin supplementation on knee pain and inflammation.
- Trial name
- NCT06581094
- Testing
- UCII, glucosamine and curcumin
- Where
- Taiwan
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Taipei Medical University
Knee Pain Chronic
Adolescent Anterior Knee Pain: ARP Wave Therapy vs. Physical Therapy
Accelerated Recovery Performance (ARP) Wave therapy is an electromyostimulation therapy designed to enhance neuromuscular control in order to rehabilitate patients with musculoskeletal pathology.
- Trial name
- NCT03225014
- Testing
- Accelerated Recovery Performance Wave Therapy, Physical therapy
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Rady Children's Hospital, San Diego
Hip Pain Chronic, Knee Pain Chronic
Effect of Buglossoides Oil on Recent Chronic Non-injurious Hip and Knee Pain
The effect of Buglossoides oil emulsion on the intensity of recent chronic knee and hip pain, on plasma and mononuclear blood cells fatty acid profiles and on whole blood Eicosapentaenoic acid production will be investigated.
- Trial name
- NCT03576625
- Testing
- High Oleic Sunflower Oil, Buglossoides Oil
- Where
- Canada
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Réseau de Santé Vitalité Health Network
Osteoarthritis, Knee
The Effect of Therapeutic Methods for Chronic Knee Osteoarthritis Pain
Chronic osteoarthritis (OA) pain of the knee is not effectively abrogated by the available non-pharmacologic or pharmacologic treatments. Radiofrequency (RF) neurotomy is a therapeutic alternative for chronic pain.
- Trial name
- NCT00924677
- Testing
- radiofrequency neurotomy for genicular nerve
- Where
- South Korea
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Asan Medical Center
Electromyography, Knee Injuries
Vastus Medialis Activation During McMurray's Test
This study will use electromyography to evaluate activation patterns of the vastus medialis and vastus lateralis muscles during the McMurray's knee examination test in different knee positions.
- Conditions
- Electromyography, Knee Injuries, Knee Pain Chronic
- Trial name
- NCT05965804
- Testing
- McMurray knee examination test
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Ahram Canadian University
Osteoarthritis of the Knee, Degenerative Osteoarthritis
Platelet-Rich Plasma and the Effects of NSAIDs on Pain and Functional Scores in Knee Osteoarthritis
The primary research purpose is to determine if the use of a drug therapy intervention (each study participant will be randomly assigned to receive one of 3 study medications which will be blinded from everyone, including the…
- Conditions
- Osteoarthritis of the Knee, Degenerative Osteoarthritis, Knee Pain Chronic
- Trial name
- PRPNSAIDsKOA (NCT05742763)
- Testing
- Ibuprofen and PRP, Acetaminophen and PRP
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- QC Kinetix LLC
Knee Pain Chronic, Knee Injuries
Treatment of Knee Pain With Topical Diclofenac Cream 8% or Diclofenac Gel 1%
Non-steroidal anti-inflammatory medication (NSAID) therapy is a mainstay treatment for joint pain and painful musculoskeletal disorders.
- Trial name
- NCT02068859
- Testing
- Diclofenac Cream 8%, Diclofenac Gel 1%
- Where
- United States
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- FPR Specialty Pharmacy
Knee Osteoarthritis, Knee Pain Chronic
The Effect of PEMF for Patients With Knee OA
Health care costs are increasing alarmingly, which will impose an overwhelming economic burden to an aging society like that of Hong Kong.
- Trial name
- NCT05548712
- Testing
- Pulse Electromagnetic Field
- Where
- Hong Kong
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Chronic Pain, Knee Pain Chronic
Cognitive Flexibility Training for Persistent Pain: Neuroimaging Pilot (COFLEX-i)
To determine whether a 5-week computer-based cognitive training intervention results in changes in resting-state functional connectivity (rsFC) within the brain networks.
- Conditions
- Chronic Pain, Knee Pain Chronic, Hip Pain Chronic, Back Pain
- Trial name
- COFLEX-i (NCT03720821)
- Testing
- Cognitive Training + fMRI
- Where
- United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Analgesia
Radiofrequency in Knee Osteoarthritis
Knee osteoarthritis is one of the most common causes of chronic pain and disability worldwide, particularly in middle-aged and elderly populations.
- Trial name
- NCT07700784
- Testing
- Laser genicular nerve ablation, Conventional radiofrequency genicular nerve ablation
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Musculoskeletal Pain, Musculoskeletal Pain Disorder
Dutch Version Fear-Avoidance Component Scale (FACS)
Chronic musculoskeletal disorders such as low back and neck pain are responsible for an enormous global burden. Fear-avoidance (FA) can be a predictor for the transition from subacute to chronic low back pain.
- Conditions
- Musculoskeletal Pain, Musculoskeletal Pain Disorder, Fear of Pain, Fear of Injury
- Trial name
- NCT03994861
- Testing
- Assessment of disability and behavior (by questionnaires)
- Where
- Belgium
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Hasselt University
Knee Osteoarthritis
Chronic Knee Pain Study
Specific Aims: 1) To examine differences between AA and white patients with knee OA in willingness to consider knee joint replacement.
- Trial name
- JRPIT (NCT00776932)
- Where
- United States
- Volunteers
- 852 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Chronic Pain
Intra-Articular 0.5 % Lidocaine Injection for Osteoarthritis
In this study, investigators compared the efficacy of intra-articular 0.5% lidocaine and saline injection on pain, stiffness and physical function in patients with osteoarthritis.
- Trial name
- NCT02632565
- Testing
- Lidocaine, Saline
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- H. Evren Eker
Postoperative Delirium, Chronic Postsurgical Pain
Peripheral Blood Single Cell Sequencing Analysis of POD and CPSP in Elderly Patients After Total Knee Arthroplasty
Single-celled sequencing for evaluating differences in gene expression patterns in different cell types of the dynamics of a means of this research as a starting point, to study the postoperative delirium and chronic pain at the…
- Trial name
- NCT05572307
- Where
- China
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Xuzhou Central Hospital
Acute Pain, Chronic Pain
The Use of Venlafaxine in Reducing Pain in Primary Total Knee Replacement
Patients experience pain after their knee replacement surgery - and some may continue to experience persistent pain long after their knee replacement surgery.
- Conditions
- Acute Pain, Chronic Pain, Knee Pain Chronic, Neuropathic Pain
- Trial name
- NCT05023278
- Testing
- Venlafaxine 37.5 MG
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Chronic Pain, Osteoarthritis, Knee
Embo Registry; National Registry for Artery Embolization
Embo Registry is a retrospective and prospective observational study to evaluate real world effectiveness and the use of Artery Embolization as a treatment for chronic pain with patients that have osteoarthritis and localized…
- Conditions
- Chronic Pain, Osteoarthritis, Knee, Osteoarthritis Thumb, Osteoarthritis Shoulder
- Trial name
- NCT06477965
- Testing
- Artery Embolization
- Where
- 2 sites in United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Vascular Solutions of North Carolina