Clinical trials: L-PRF
Periodontitis
Efficacy of PRF With M-MIST in the Treatment of Intrabony Defects
This study evaluates the efficacy of M-MIST with or without PRF in the treatment of intrabony defects.Taking into consideration of advantages of PRF and M-MIST it was hypothesised that this combination (PRF+M-MIST) would be more…
- Trial name
- NCT03169920
- Testing
- Modified-Minimally Invasive Surgical Technique + PRF, Modified-Minimally Invasive Surgical Technique
- Where
- India
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Thin Gingival Biotype
Comparative Evaluation of Vitamin C and Injectable-platelet Rich Fibrin in the Management of Thin Gingival Phenotype
The goal is to compare between the effect of vitamin C and Injectable-platelet rich fibrin in the management of thin gingival phenotype.
- Trial name
- NCT05841303
- Testing
- Vit C, injectable PRF
- Where
- Egypt
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Cairo University
Gingival Recession
Cytokine and MMP Levels in Gingival Crevicular Fluid in the Treatment of Localized Gingival Recessions
The main objective of this study was to evaluate the matrix metalloproteinase (MMP)-8, and -9, tissue inhibitor of matrix metalloproteinase and interleukin-1beta levels in gingival crevicular fluid during the early and late…
- Trial name
- NCT02380872
- Testing
- Connective tissue graft, Platelet Rich Fibrin
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Ege University
Gingival Recession
Effect of Dose-dependent Platelet Rich Fibrin(PRF)
Miller Class I Gingival Recessions (GR) have been treated by using Coronally Advanced Flap (CAF) with Platelet Rich Fibrin membrane (PRF membrane) or Connective Tissue Graft (CTG).
- Trial name
- PRF (NCT02882464)
- Testing
- PC-02 Centrifuge device,2PRF+CAF, PC-02 Centrifuge device, 4 PRF+CAF, CTG+CAF
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Gazi University
Temporomandibular Joint Disorders
Evaluation of Anterior Repositioning Guided Splint Combined With or Without I Platelet-rich Fibrin
The study aims to evaluate clinically and radiographically the effectiveness of arthrocentesis and injection of I-PRF with wearing ARS in comparison to arthrocentesis and ARS only.
- Trial name
- NCT06132802
- Testing
- Patients who received treatment involving ARS and arthrocentesis only, Patients who received treatment involving ARS, arthrocentesis, and an I-PRF injection
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Mahmoud Mohammed Mahmoud Nasef
Bone Loss
Release Kinetics of rhBMP-2 Using E-PRF as an Autologous Carrier: An In Vitro Analysis
This study is seeking to evaluate the binding of a commercially-available, recombinant human osteoinductive growth factor, rhBMP-2, to a human blood derived product scaffold, enhanced Platelet-rich fibrin (E-PRF), and the release…
- Trial name
- NCT04670965
- Testing
- E-PRF/rhBMP-2 (similar ratios), E-PRF/ACS/rhBMP-2, rhBMP-2/E-PRF
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Platelet-Rich Fibrin
Titanium-prepared Platelet-rich Fibrin in Periodontal Regeneration
In this study, the possible effect of blood group distribution on the content of blood biomaterial was investigated. 64 volunteers were included in the study. Various parameters were evaluated.
- Trial name
- NCT05409495
- Testing
- periodontal surgical procedure (open flap debridement), periodontal surgical procedure (OFD +autogenous Titanium-prepared platelet-rich fibrin (OFD+ T-PRF))
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Ataturk University
Pain, Wound Healing
Effect of PRF Palatal Bandage on Pain Scores and Wound Healing After Free Gingival Graft
Background: Free gingival graft (FGG) is used to increase keratinized tissue dimensions. This prospective clinical trial was conducted aiming to determine whether the addition of an autologous platelet-rich fibrin (PRF) would…
- Trial name
- NCT02797899
- Testing
- Platelet Rich Fibrin
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- King Abdulaziz University
Extraction, Tooth, Tooth Fracture
Platelet-Rich Fibrin (PRF) vs Bone Graft With Membrane for Ridge Preservation After Tooth Extraction
This study uses a natural material called Platelet-Rich Fibrin (PRF) to help improve healing after tooth removal. PRF is made from your own blood.
- Conditions
- Extraction, Tooth, Tooth Fracture, Tooth Crown Fracture, Root; Fracture
- Trial name
- NCT07595198
- Testing
- Platelet-rich fibrin (PRF), Freeze-dried bone allograft, Collagen barrier membrane
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Alveolar Ridge Enlargement
Leukocyte-platelet Rich Fibrin for Alveolar Ridge Preservation
After tooth extraction, there is a subsequent bone loss as a part of the natural healing of the tissue. Up to 50% of bone loss occurs during the first three months after extraction, jeopardizing a possible implant treatment.
- Trial name
- L-PRF (NCT05572242)
- Testing
- Premolar extraction and socked preservation with L-PRF, Premolar extraction and socked preservation with Xenogenic bone and collagen membrane.
- Where
- Chile
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Universidad de los Andes, Chile
Furcation Defects
Platelet Rich Fibrin+1% Alendronate in Treatment of Mandibular Degree II Furcation Defects
The present study was designed to evaluate the combined efficacy of PRF and 1% ALN in the treatment of mandibular degree II furcation defects when compared with PRF and open flap debridement (OFD) alone.
- Trial name
- NCT02609061
- Testing
- Open flap debridement (OFD), OFD with Platelet rich fibrin (PRF), OFD with Platelet rich fibrin (PRF)+1% Alendronate (Drug) in gel form
- Where
- India
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Government Dental College and Research Institute, Bangalore
Bone Loss
Using of Injectable Platelet Rich Fibrin on Filling the Gap of Immediate Dental Implant
The effect of using of i-PRF (injectable platelet rich fibrin) on filling the gap of immediate dental implant in the esthetic zone
- Trial name
- NCT04298294
- Testing
- injectable platelet rich fibrin
- Where
- Egypt
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Periodontitis Chronic Generalized Severe, Periodontitis Chronic Generalized Moderate
Scaling and Root Planning With Localized Delivery of Autogenous Growth Factors- Platelet Rich Fibrin (PRF)
The purpose of this research study is to find out about the effect of growth factors extracted from blood on improving healing of periodontal pockets (Gum pockets) after deep gum cleaning.
- Trial name
- NCT04978324
- Testing
- leukocyte platelet rich fibrin (L-PRF), Scaling and Root Planing
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Virginia Commonwealth University
Effect of Piezocision and Injectable Platelets Rich Fibrin on Tooth Movement
Evaluation of Piezocision Versus Injectable Platelet-rich Fibrin During Orthodontic Canine Retraction Orthodontic Canine Retraction: A Comparative Clinical Study
Comparison of piezocisin and injectable platelets rich fibrin during canine retraction
- Trial name
- NCT07239024
- Testing
- Iprf and piezocision
- Where
- Egypt
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Bone Resorption
Guided Bone Regeneration Using Bovine-derived Xenograft in Combination With or Without Injectable Platelet-rich Fibrin
The aim of the study was to compare the change in augmentation thickness after guided bone regeneration (GBR) using bovine-derived xenograft in combination with or without injectable platelet-rich fibrin (i-PRF).
- Trial name
- NCT04709523
- Testing
- bovine-derived xenograft with i-PRF, bovine-derived xenograft alone
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Ege University
Implant or Graft; Rejection
Effect Of PRF Versus Xenograft In Closed Sinus Lift.
Indirect sinus lift with used PRF as a graft material versus xenograft
- Trial name
- NCT03684954
- Testing
- Prf
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Mahmoud adel shaaban
Periodontitis
Effects of PRF and i-PRF on Clinical and Biochemical Parameters in Non-Surgical Periodontal Therapy
The goal of this clinical trial is to learn if adding platelet-rich fibrin (PRF) or injectable platelet-rich fibrin (i-PRF), obtained from the participant's own blood, to standard non-surgical periodontal treatment helps improve…
- Trial name
- PRF-NSPT (NCT07525531)
- Testing
- Non-surgical periodontal therapy (NSPT), Platelet-rich fibrin (PRF), Injectable platelet-rich fibrin (i-PRF)
- Where
- Turkey (Türkiye)
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Ondokuz Mayıs University
Periodontitis, Adult
Advanced Platelet-rich Fibrin Combined With Open Debridement in Management of Suprabony Periodontal Defects
in this clinical trial, patients with periodontal defects will be treated with advanced platelet-rich fibrin in conjunction with open debridement
- Trial name
- NCT05730153
- Testing
- advanced PRF
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- October University for Modern Sciences and Arts
Gingival Recession
Treatment of Gingival Recession Defects Using Platelet-Rich Fibrin With an Allogenic Dermal Matrix
The study aims to test the non-inferiority of an Allogenic Dermal Matrix with Platelet-Rich Fibrin for treatment of gingival recessions in comparison to the Connective Tissue Graft.
- Trial name
- NCT05819515
- Testing
- Tunneled coronally advanced flap
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Michigan
L-PRF, Surgery
Root Coverage for Gingival Recessions: a Randomized Clinical Trial Using Coronally Advanced Tunnel Technique and Novomatrix®
A randomized clinical trial comparing the modified tunnel technique with the use of acellular xenogeneic matrix and connective tissue with the use leucocyte platlet rich fibrin (L-PRF)
- Trial name
- NCT06719648
- Testing
- Acellular dermal matrix + L-Prf, Connective Tissue graft + L-Prf
- Where
- Spain
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Universitat Internacional de Catalunya