Clinical trials: Labor, Obstetric
Abnormal Labor, Failed Induction of Labor
Enhanced vs. Routine Clear Liquid Intake in Labor
The goal of the study is to see if the addition of a carbohydrate- and protein-enhanced gel during labor speeds labor and reduces the rate of cesarean delivery.
- Conditions
- Abnormal Labor, Failed Induction of Labor, Ketosis
- Trial name
- NCT02524002
- Testing
- Accel Gel, Usual clear diet
- Where
- United States
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Temple University
Preterm, Nutritional Deficiency
An Exploratory Study of Increased Preterm Arginine INTake (PAINT18)
PAINT18 is a nutrition study focusing on the effect of arginine supplementation on immune function in preterm infants. The investigators will explore the effect of current intravenous feeding (parenteral nutrition (PN)…
- Conditions
- Preterm, Nutritional Deficiency, Immune System and Related Disorders
- Trial name
- PAINT18 (NCT05299112)
- Testing
- Arginine
- Where
- United Kingdom
- Volunteers
- 24 people
- Sponsor
- Liverpool Women's NHS Foundation Trust
Premature Birth, Premature Labor
Trial of Magnesium Sulfate Tocolysis Versus Nifedipine Tocolysis in Women With Preterm Labor
Primary Hypothesis: Acute tocolysis (48 hours) using oral nifedipine is more effective than intravenous magnesium sulfate in prolonging pregnancy in women with preterm labor with intact membranes between 24 and 32 6/7 weeks'…
- Trial name
- NCT00306462
- Testing
- Magnesium sulfate
- Where
- United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- University of Cincinnati
Neonatal Respiratory Distress Syndrome
Impact of Neurophysiological Facilitation of Respiration in Preterm Neonates
Background: Respiratory distress syndrome (RDS) or Neonatal respiratory distress syndrome (NRDS) is characterized by pulmonary insufficiency, in preterm neonates and is the major cause of death in preterm.
- Trial name
- NCT04019886
- Testing
- Neurophysiological Facilitation of Respiration
- Where
- India
- Volunteers
- 30 people
- Sponsor
- Asir John Samuel
Respiratory Morbidity, Preterm Labor
Low Dose Antenatal Corticosteroids for Late Preterm Delivery
This is a study proposal for a clinical trial to evaluate the effectiveness of a reduced dose of antenatal betamethasone (a steroid medication) in preventing respiratory problems in late preterm infants (born between 34 and 36…
- Trial name
- LoDAC (NCT05698966)
- Testing
- we will use reduced dose of acceptable corticosteroids treatment for preterm birth
- Where
- 16 sites in Israel
- Volunteers
- 1,510 people
- Sponsor
- Rambam Health Care Campus
Labor, First Stage, Labor, Second Stage
Effect of Dianatal Obstetric Gel (Cross-linked Polyacrylic Acid) on Outcomes in Vaginal Delivery
Perineal massage at the end of labor stage 2 has been investigated in 2 randomized controlled trials using a water soluble lubricant.
- Trial name
- NCT01546129
- Testing
- Dianatal Obstetric Gel (Cross-linked polyacrylic acid)
- Where
- Israel
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Rabin Medical Center
Vitamin B-12 Deficiency
THE B-BABIES STUDY: An Observational Study of Group B Vitamins in Preterm Infants
Infancy may be associated with a risk of micronutrient depletion due to the high demands of rapid growth. This is particularly true when preterm birth occurs, as the period before term exhibits the highest rate of bodily growth…
- Trial name
- B-BABIES (NCT07163962)
- Where
- United Kingdom
- Volunteers
- 40 people
- Sponsor
- Norfolk and Norwich University Hospitals NHS Foundation Trust
Retinopathy of Prematurity (ROP)
The Effect of Two Non-Pharmacological Methods on Pain During Retinopathy Examination
The goal of this randomized controlled trial is to determine the effect of reverse kangaroo care position and ROP (Retinopathy of Prematurity) position applied during ROP examination in premature infants on pain.
- Trial name
- NCT06694103
- Testing
- Reverse Kangaroo Care Position, ROP Position
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Sinem Basdemir
Preterm Birth
Philadelphia Preterm Prevention Project
This is a randomized clinical trial in which all Philadelphia resident women experiencing a pre-term birth (PTB) at <34 weeks of gestation (GA) over an 18 month period will be approached at the time of the postpartum hospital…
- Trial name
- PPP (NCT01117922)
- Testing
- Psychological intervention, Usual Care Group
- Where
- United States
- Volunteers
- 1,136 people
- Sponsor
- Children's Hospital of Philadelphia
Premature
Effect of Docosahexaenoic Acid (DHA)-Enriched Human Milk in Premature Newborns
Several recent publications showed a reduction in the level of DHA and/or an increase in the arachidonic acid (AA)/DHA ratio in the milk of mother.
- Trial name
- DHARMA (NCT01062373)
- Testing
- Supplementation of lactating mothers who has delivered prematurely with DHA
- Where
- France
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Preterm Birth, Low; Birthweight, Extremely (999 Grams or Less)
Clinical Evaluation of the "NICU Clinical Decision Support Dashboard" - CHMCO
This study evaluates the use of a NICU clinical integration system (Dashboard and accessories) in improving the quality of care delivered, patient health outcomes, and parent and clinician satisfaction.
- Conditions
- Preterm Birth, Low; Birthweight, Extremely (999 Grams or Less), Neonatal Infection, Satisfaction
- Trial name
- NCT03673566
- Testing
- NICU Dashboard
- Where
- United States
- Sponsor
- Philips Healthcare
Respiratory Syncytial Virus Infection, Premature Birth
Palivizumab for Prevention of Severe Respiratory Syncytial Virus Infection in Russian Children
100 Russian children of 2 years of age and less in high-risk populations (preterm, and/or with heart and lung problems) will receive palivizumab (Synagis) 15 mg/kg intramuscularly as prophylaxis to severe respiratory syncytial…
- Conditions
- Respiratory Syncytial Virus Infection, Premature Birth, Bronchopulmonary Dysplasia, Congenital Heart Disease
- Trial name
- NCT01006629
- Testing
- palivizumab
- Where
- 19 sites in Russia
- Volunteers
- 100 people
- Sponsor
- Abbott
Infant, Premature, Diseases
The Effect of Diaper Change Position on Preterm Infants
The purpose of this study is to determine the effect of diaper change position on neonatal comfort and heart rate, respiratory rate and oxygen saturation in preterm infants.
- Trial name
- NCT04528602
- Testing
- Control (Extended leg position) Group, Experimental (Legs are flexed toward abdomen) Group
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Acibadem University
Premature (Early) Ejaculation
Comparative Evaluation of Safety and Efficacy of Dapoxetine, Silodosin, and Citalopram in the Management of Premature Ejaculation
This randomized controlled trial evaluated the comparative effectiveness and safety of four pharmacological treatments-Citalopram 20mg, Silodosin 4 mg, Dapoxetine 30 mg on demand, and Dapoxetine 30 mg daily-in men with premature…
- Trial name
- NCT07113145
- Testing
- Oral intake of medication
- Where
- Egypt
- Volunteers
- 450 people
- Sponsor
- Beni-Suef University
Placenta Accreta
Placenta Accreta Spectrum Management: Uterine Preservation Using JSICA Technique - Retrospective Cross-Sectional Study
The goal of this study is to present the Jakarta Surgical Uterine Conservation (JSICA) technique and its perioperative outcomes in Placenta Accreta Spectrum patients.
- Trial name
- NCT05871645
- Testing
- Jakarta Surgical Uterine Conservation (JSICA) Technique, Standard Hysterectomy
- Where
- Indonesia
- Volunteers
- 323 people
- Sponsor
- Dr Cipto Mangunkusumo General Hospital
Hemorrhage Postpartum, Fertility Disorders
Fertility After Intrauterine Tamponing Balloon: Where Are we
Today, few data are available on the patient's fertility following intrauterine tamponade balloon (BTIU) used for postpartum hemorrhage (PPH) after vaginal delivery (AVB).
- Trial name
- FERTIBTIU (NCT04133402)
- Where
- France
- Volunteers
- 59 people
- Sponsor
- University Hospital, Lille
Preterm Birth
Activity Restriction for Women With Arrested Preterm Labor
to test the hypothesis that activity restriction in women with singleton gestations and with arrested PTL would reduce the rate of PTB.
- Trial name
- NCT03501030
- Testing
- Activity restriction
- Where
- Italy
- Volunteers
- 120 people
- Sponsor
- Federico II University
Premature Labor, Pregnancy
Indomethacin PK and PD Therapy in Pregnancy
This study will follow pregnant women who are taking indomethacin as Standard of Care (SOC) for the indications of preterm labor (PTL), short cervix, or other indications, to evaluate the pharmacokinetics (PK), what the body does…
- Conditions
- Premature Labor, Pregnancy, Premature Birth
- Trial name
- NCT02451228
- Testing
- Serial blood collection
- Where
- 6 sites in United States
- Volunteers
- 62 people
- Sponsor
- The University of Texas Medical Branch, Galveston
Placenta Accreta Spectrum
New Conservative Technique for Placenta Accreta Spectrum
participants diagnosed as placenta accreta spectrum were subjected to cesarean delivery. Investigators manually detected a plan of cleavage through which the placenta was separated followed by closure of defective placental bed.
- Trial name
- percreta (NCT04427592)
- Testing
- ultrasound, closure of uterine wall defect
- Where
- Egypt
- Volunteers
- 159 people
- Sponsor
- Alexandria University
Preterm Birth, Low Birth Weight
Diagnostic Accuracy of Foot Length in Predicting Preterm and Low Birth Weight Using Ultrasound Dating as The Gold Standard in a Rural District of Pakistan
Background: The burden of preterm and low birth weight babies (LBW) is high in low- and middle-income countries (LMICs). Therefore, assessment of gestational age (GA) and birth weight is important.
- Trial name
- NCT05515211
- Testing
- Foot length
- Where
- Pakistan
- Volunteers
- 336 people
- Sponsor
- Aga Khan University
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