Clinical trials: Labor Analgesia
Labor Pain and to Reduce Pain
Investigation of the Analgesic Effects of Intradermal and Subdermal Sterile Water Injection on Active Labor Pain
Labour pain has different locations, intensity, quality and meaning for each woman, and the experience of pain changes throughout the delivery process.
- Trial name
- NCT06214663
- Testing
- 0.9 NaCl solution
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Ankara City Hospital Bilkent
Complication of Labor and/or Delivery
Efficacy and Satisfaction With Remifentanil Analgesia in Parturients During the Childbirth
Retrospective observational study to determine the efficacy of remifentanil during the delivery. Authors will search the data in period between 2010 and 2014 in cohort of 100 parturients and obtain data of analgesic efficacy (VAS…
- Trial name
- NCT02447757
- Testing
- remifentanil
- Where
- 2 sites in Czechia
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Brno University Hospital
Labor Pain
Changes in Velocimetric Indices of Uterine and Umbilical Arteries Before and After Combined Spinal-epidural Analgesia in Laboring Women
Combined spinal-epidural (CSE) for labor analgesia has been used for many years and is practiced commonly at our institution, especially when the patient requests immediate pain relief.
- Trial name
- NCT05512065
- Testing
- Ultrasound
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Post-dural Puncture Headache, Post-dural Puncture Backache
Long-term Effects of Accidental Dural Puncture in Patients Having Had an Epidural Blood Patch (LEAP)
Accidental dural puncture (ADP) during placement of an epidural catheter for anesthesia and analgesia is a well known complication. Previous studies have found audiometric deterioration following ADP.
- Trial name
- LEAP (NCT02149680)
- Where
- 2 sites in Sweden
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Örebro University, Sweden
Midwifery, Pregnancy
Evaluation of the Effectiveness of Transcutaneous Electrical Nerve Stimulation During Labor.
This study evaluates the effectiveness of the Transcutaneus Electric Nerve Stimulation (TENS) during the labour. TENS is a low frequency electrotherapy technique, analgesic type, generally used in musculoskeletal pathology.
- Trial name
- NCT03137251
- Testing
- TENS 1, TENS 2
- Where
- Spain
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- University of Las Palmas de Gran Canaria
Obesity, Labor Onset and Length Abnormalities
Ambulation With Labor Epidural in Obese Women
The purpose of this study is to determine if ambulation with a labor epidural in place is associated with decreased rate of cesarean delivery in obese patients.
- Trial name
- NCT04504682
- Testing
- Ambulation
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Labor Pain
Programmed Intermittent Epidural Bolus for Labor Analgesia During First Stage of Labor 2
Brief Summary: Until recently, at Mount Sinai Hospital, epidural analgesia for labor pain was delivered with a pump that could only provide continuous infusion of the freezing medication in combination of pushes of medication…
- Trial name
- NCT02758405
- Testing
- Bupivacaine, Fentanyl, Infusion pump
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Breech Presentation, Pregnancy
Remifentanil Versus Paracetamol for Pain Treatment External Cephalic Versions.
BACKGROUND: Between 3-4% of pregnancies carried to term, the fetuses are in breech presentation. The external version is a maneuver gynecological used to turn a breech in cephalic presentation.
- Trial name
- NCT01048398
- Testing
- remifentanil, paracetamol
- Where
- Spain
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Basque Health Service
Labor Pain
Does Ultrasound Scanning of the Lumbar Spine Improve Patient Satisfaction and the Ease of Insertion Epidurals?
Ultrasound scanning of the back has been shown to increase success when used to guide epidural catheter insertion. However, this technique is not applied widely in clinical practice.
- Trial name
- NCT00996905
- Testing
- Portable ultrasound machine
- Where
- Canada
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Labor Pain
CSE for Labour Analgesia: A Comparison of Two Intrathecal Regimens
Analgesia in labour is not readily available in many parts of Sub-Saharan Africa. The overall cost of Epidural services in terms of human personnel and financial implication makes this inaccessible to many women in labour.
- Trial name
- SSS (NCT03117595)
- Testing
- Bupivacaine-fentanyl, Bupivacaine-fentanyl morphine
- Where
- Nigeria
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Sarah Beckley
Analgesia, Obstetrical
Paracetamol for Intrapartum Analgesia
The aim of this study is to assess whether paracetamol is as effective as pethidine for analgesia during the first stage of labor.
- Trial name
- NCT02578251
- Testing
- Paracetamol, Pethidine
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Ain Shams Maternity Hospital
Labor Pain, Analgesia
Optimal Bupivacaine Dose for Initiation of Labor Epidural Techniques
To estimate the dose of bupivacaine required to achieve initial effective comfort in 90% of patients (ED90) via the epidural (DPE or EPL) technique in women undergoing labor.
- Trial name
- NCT04814537
- Testing
- Bupivacaine Hydrochloride
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Labor Pain, Pregnancy
Neuraxial Versus Systemic Analgesia for Latent Phase Labor Effect on Rate of Operative Delivery
The purpose of this study in nulliparous women undergoing induction of labor is to determine whether initiation of neuraxial analgesia compared to systemic opioid analgesia early in labor (< 4 cm cervical dilation)affects the…
- Trial name
- NCT00380978
- Testing
- combined spinal epidural analgesia, late analgesia (systemic)
- Where
- United States
- Volunteers
- 1,026 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Labor Pain
Inhaled Nitrous Oxide and Labor Analgesia
Hypothesis: The administration of nitrous oxide for labor analgesia will decrease the labor epidural anesthesia rate by 15%. Specific Aim: To determine if nitrous oxide can be an effective alternative technique for the provision…
- Trial name
- NCT01738672
- Testing
- Inhaled nitrous oxide
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Ya'aqov Abrams
Childbirth, Aromatherapy
Comparison Of The Effects Of Swedish Massage With Natural Oils
Aim: This study aimed to evaluate the effects of Swedish massage combined with lavender and chamomile oils on childbirth outcomes during the first and second stages of labor.
- Conditions
- Childbirth, Aromatherapy, Pain Management, Fear
- Trial name
- Comparison (NCT07652957)
- Testing
- Aromatherapy and Massage Care for labor pain management
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Kutahya Health Sciences University
Analgesia, Obstetrical
Hyoscine ButylBromide for Intrapartum Analgesia
The aim of this study is to assess whether hyoscine butylbromide is as effective as pethidine for analgesia during the first stage of labor.
- Trial name
- NCT02557087
- Testing
- Hyoscine, Pethidine
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Ain Shams Maternity Hospital
Epidural, Labor Pain
Improving Labour Induction Analgesia: Epidural Fentanyl Bolus at Epidural Initiation for Induction of Labour
Labour pain can be intensified for labour inductions and women undergoing inductions often have earlier and more frequent requests for analgesia.
- Conditions
- Epidural, Labor Pain, Induction of Labor Affected Fetus / Newborn, Obstetric Anesthesia Problems
- Trial name
- NCT04011098
- Testing
- Epidural Fentanyl Bolus, Standard Epidural Group
- Where
- Canada
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- University of Saskatchewan
Pregnancy, Vaginal Delivery
The Impact of an Epidural Ropivacaine-Neostigmine Injection for Perineal Analgesia at the End of Labor.
Perineal pain after childbirth occurs in the majority of women (with or without episiotomy). Perineal pain can become source of chronic pain in 9%-12% of the cases.
- Trial name
- NCT00407290
- Testing
- neostigmine
- Where
- Belgium
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Labor Pain
Programmed Intermittent Epidural Bolus for Labor Analgesia During First Stage of Labor: A Sequential Allocation Trial to Determine the Optimum Interval Time Between Boluses of a Fixed Volume of 2.5ml of Bupivacaine 0.25% Plus Fentanyl 8 mcg/ml
Programmed intermittent epidural bolus (PIEB) is a technique of epidural analgesia in which boluses of local anesthetic solutions are injected into the epidural space at a fixed time interval.
- Trial name
- NCT03735771
- Testing
- Bupivacaine
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Vaginal Delivery, Normal Labor
Comparative Analysis of Analgesic Efficacy: by Single Shot Intrathecal Analgesia (SSSA) in Normal Labor
the goal of this randomized control trial is to compare the effect of adding fentanyl v.s dexmedetomidine to bupivacaine in single shot spinal analgesia in achievement of analgesia by decreasing visual analogue scale, onset and…
- Trial name
- SSSA (NCT06823349)
- Testing
- Dexmedetomidine, fentanyl, Saline 0.9%
- Where
- Egypt
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Jehan George Sadek