Clinical trials: Labor Augmentation
Labor Onset and Length Abnormalities, Uterine Rupture
Breast Stimulation vs. Low Dose Oxytocin Augmentation for Labor Induction
To find the preferred method of labor induction (birth augmentation) for women with a history of one prior cesarean section scar and in grandmultiparas, the difference in time interval from augmentation to delivery will be…
- Conditions
- Labor Onset and Length Abnormalities, Uterine Rupture, Birth; Induced
- Trial name
- NCT05510310
- Testing
- Breast stimulation, Oxytocin
- Where
- Israel
- Volunteers
- 200 people
- Sponsor
- Western Galilee Hospital-Nahariya
Prolonged Labor, Labor Dystocia
Efficacy of Bicarbonate on the Risk of Assisted Delivery in Nulliparous Women With Prolonged Labour
The goal of this clinical trial is to learn if oral bicarbonate can treat prolonged labour in nulliparous women with prolonged labour.
- Trial name
- ProLabour (NCT07321379)
- Testing
- Sodium bicarbonate
- Where
- 3 sites in Denmark
- Volunteers
- 1,520 people
- Sponsor
- Copenhagen University Hospital, Hvidovre
Labor Fast
Safety Study of Hyoscine N Butyl Bromide in Active Management of Labor
Although Hyoscine N butyl bromide (HBB) is used liberally to facilitate cervical dilatation, there is little and inconclusive data about its efficacy.
- Trial name
- HBB (NCT02098889)
- Testing
- hyoscine-N-butyl bromide(HBB), Saline
- Where
- Turkey (Türkiye)
- Volunteers
- 382 people, healthy volunteers welcome
- Sponsor
- Sisli Hamidiye Etfal Training and Research Hospital
Augmentation, Induction
The Effect of Consumption of Date Fruit and Nipple Stimulation in Late Pregnancy
The study was conducted to determine the effect of consumption of date fruit and nipple stimulation on labor. The samples were applied to pregnant women satisfying the research criteria in a state hospital in Istanbul between…
- Conditions
- Augmentation, Induction, Labor, Stimulation, Self
- Trial name
- NCT06280911
- Testing
- Date Fruit group, Nipple group
- Where
- Turkey (Türkiye)
- Volunteers
- 198 people, healthy volunteers welcome
- Sponsor
- Selcuk University
Labor Augmentation
A Trial of Oral Misoprostol for Labor Augmentation
This is a prospective, randomized, controlled trial designed to examine the efficacy of oral misoprostol for labor augmentation compared to a standard regimen of intravenous oxytocin.
- Trial name
- NCT00906347
- Testing
- Misoprostol, Oxytocin
- Where
- United States
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Labor Progression, Pregnancy
Effects of Sleep Quality, Anxiety, and Digital Behavior on Labor Progression in Term Primiparous Women: A Prospective Observational Study
This prospective observational study evaluates whether maternal sleep quality, anxiety levels, and nighttime digital behavior are associated with labor progression among term primiparous women.
- Trial name
- SAD-LABOR (NCT07299708)
- Testing
- No Intervention: Observational Cohort
- Where
- Turkey (Türkiye)
- Volunteers
- 127 people, healthy volunteers welcome
- Sponsor
- Tepecik Training and Research Hospital
Prolonged Labor
Amniotomy and Oxytocin for Augmentation of Labour
Prolonged labour is a cause of maternal mortality and morbidity and perinatal mortality and morbidity. Prolonged labour is most often defined as onset of regular , rhythmical painful contractions accompanied by cervical…
- Trial name
- AOAL (NCT02318121)
- Testing
- Amniotomy first, Oxytocin first, Amniotomy and oxytocin
- Volunteers
- 150 people
- Sponsor
- Assiut University
Birth; Delayed
High Dose Versus Low Dose Oxytocin for Augmentation of Delayed Labour
In a randomized control trial conducted in six study centers/labour wards in Sweden, consenting nulliparous women in active phase of labour and with a defined delayed labour progress will be randomized to receive a regimen of…
- Trial name
- OxyHighLow (NCT01587625)
- Testing
- Oxytocin
- Where
- 2 sites in Sweden
- Volunteers
- 1,376 people
- Sponsor
- Göteborg University
Arrest of Dilation in Labor
Oral Misoprostol for Labor Augmentation: A Pilot Study
A phase I, open-label trial to determine a safe dose of oral misoprostol required to augment labor in nulliparous women diagnosed with arrest of dilation.
- Trial name
- NCT00906126
- Testing
- Misoprostol
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- University of Texas Southwestern Medical Center
Schizophrenia
Pharmacologically-augmented Cognitive Therapies (PACTs) for Schizophrenia.
This application seeks renewed support for MH59803, "Dopaminergic substrates of startle gating across species," to extend a clear path of "bench-to-bedside" progress towards a critical paradigm shift in therapeutic models for…
- Trial name
- NCT02634684
- Testing
- Dextroamphetamine
- Where
- United States
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Slow Labour Progress
Labour Augmentation by Means of Oxytocin - Obstetric Outcome and Women's Experiences
Slow labour progress is common in nulliparous women and is associated with childbirth complications and negative birth experiences. Oxytocin augmentation is widely used to treat slow labour despite associated risks for the fetus.
- Trial name
- NCT01263158
- Testing
- Expectancy of standard oxytocin treatment
- Where
- Sweden
- Volunteers
- 2,072 people
- Sponsor
- Göteborg University
Instrumental Vaginal Births, Oxytocin Augmentation for Labor
The Swedish Birth Seat Trial
The purpose of this study is to determine whether birth on a birthing seat will effect numbers of instrumentally assisted vaginal births, vaginal traumas, blood loss,use of artificial oxytocin for labour augmentation and fetal…
- Conditions
- Instrumental Vaginal Births, Oxytocin Augmentation for Labor, Maternal Blood Loss, Perineal Outcomes
- Trial name
- NCT01182038
- Testing
- BirthRite birthing seat
- Where
- Sweden
- Volunteers
- 1,002 people, healthy volunteers welcome
- Sponsor
- Helsingborgs Hospital
Injury of the Anterior Cruciate Ligament (ACL)
Clinical and Functional Outcomes 2 Years After ACL Repair and InternalBrace Ligament Augmentation in Comparison With ACL Reconstruction
The aim of this study is to assess the clinical, biomechanical and functional outcome 2 years after anterior cruciate ligament (ACL) repair and InternalBraceTM augmentation now in direct comparison to ACL reconstruction and to…
- Trial name
- RetroBRACE II (NCT04429165)
- Testing
- collection of Patient Reported Outcome (PRO) data, collection of anthropometric and clinical functional data, gait analysis
- Where
- Switzerland
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Dystocia
Comparison of Low-dose and High-dose Oxytocin Regimens for Labor Augmentation
Oxytocin is a medication that is often used to strengthen contractions to overcome delayed labor progress. The primary aim of this study is to determine whether receiving a higher dose of oxytocin lowers the chance of needing a…
- Trial name
- NCT02487797
- Testing
- Oxytocin, Sodium Chloride 0.9%
- Where
- United States
- Volunteers
- 1,003 people
- Sponsor
- Northwestern University
Pregnancy, Labor Pain
Association Between Fluid Administration, Oxytocin Administration, and Fetal Heart Rate Changes
Fetal heart rate patterns are an important parameter in the diagnosis of non-reassuring fetal status. Combined-spinal epidural analgesia is a method of initiating labor analgesia used by approximately 90% of the parturients at…
- Trial name
- NCT02121184
- Testing
- Routine oxytocin, Half-dose oxytocin
- Where
- United States
- Volunteers
- 172 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Vaginal Delivery
Effect of Intravenous Hyoscine Butylbromide Injection on First Stage Labour in Primigavidae
A case control study conducted on 120 women coming to Cairo University Maternity Hospital .Patients who meet the inclusion criteria were asked to participate in the study and a verbal consent was obtained from each patient.
- Trial name
- NCT02824679
- Testing
- hyoscine butylbromide, saline
- Volunteers
- 200 people
- Sponsor
- Ahmed M Maged, MD
Labor
Efficacy and Safety Study of Titrated Oral Misoprostol Solution for Labor Augmentation
The purpose of this study is to compare the efficacy and safety of titrated oral misoprostol solution with intravenous oxytocin for labor augmentation in women without adequate uterine contractions.
- Trial name
- NCT00695331
- Testing
- Misoprostol, Oxytocin
- Where
- Taiwan
- Volunteers
- 143 people
- Sponsor
- China Medical University Hospital
Duration of Labor
Does Oral Propranolol Accelerate Labor Induction/Augmentation With Oxytocin in Nulliparous Women in Abakaliki?
Labour is usually physiologic, spontaneous and progressive, but occasionally, there may be the need for induction or augmentation of labour especially in nulliparous women, who are at increased risk of dysfunctional labour.
- Trial name
- NCT05251610
- Testing
- 20mg oral propranolol and oxytocin, Oxytocin only
- Where
- Nigeria
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Darlington-Peter Chibuzor Ugoji
Induction of Labor, Augmentation of Labor
Comparing High Versus Low Dose of Oxytocin, in Gravida Women With BMI 30 and Above Which Are Undergoing Induction of Labor
The goal of this clinical trial is to compare between higher and lower dose of oxytocin to induce delivery in obese women. Researches will compare between low and high doses of oxytocin.
- Trial name
- NCT06990217
- Testing
- Oxytocin Grindeks 10 IU/ml- solution for injection
- Where
- Israel
- Volunteers
- 130 people
- Sponsor
- HaEmek Medical Center, Israel
Schizophrenia, Cognitive Deficits
Augmentation of Working Memory Training With Transcranial Direct Current Stimulation in Patients With Schizophrenia
Cognitive impairment is a core symptom of schizophrenia and is in a large part responsible for the poor psychosocial outcome of the disorder.
- Trial name
- NCT03621540
- Testing
- active tDCS, Adaptive working memory training
- Where
- 2 sites in Germany
- Volunteers
- 37 people
- Sponsor
- University Hospital Tuebingen