Clinical trials: Labor Complication
Anti-Mullerian Hormone Deficiency, Post Partum Hemorrhage
Anti-Mullerian Hormone (AMH) is a Marker for Ovarian Reserve. There Are Many Studies About AMH Changes in Ovarian Surgery, But Little is Known for Other Surgeries. We Seek to Investigate the Hormone Variations Before and After Uterine Artey Ligation for Postpartum Hemorrage (PPH)
Anti-Mullerian hormone (AMH) is a marker for ovarian reserve. There are many studies about AMH changes in ovarian surgery, but little is known for other surgeries.
- Trial name
- NCT03907605
- Testing
- anti- mullerian hormone
- Where
- Turkey (Türkiye)
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Cerebral Palsy, Prematurity
Best Practices Fo Early Diagnosis of Cerebral Palsy
In this research, the investigators are using an implementation science approach to enhance the uptake of a clinical practice guideline for earlier diagnosis of cerebral palsy (i.e.
- Trial name
- CP (NCT06537622)
- Testing
- Implementation group, Standard of care
- Where
- Canada
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- St. Justine's Hospital
Cesarean Delivery, Postpartum Hemorrhage (PPH)
Topical Tranexamic Acid to Reduce Blood Loss During Cesarean Delivery
The goal of this clinical trial is to learn whether applying topical tranexamic acid (TXA) directly to the uterine incision during cesarean delivery can reduce surgical bleeding compared to placebo.
- Conditions
- Cesarean Delivery, Postpartum Hemorrhage (PPH), Intraoperative Blood Loss, Hemostasis
- Trial name
- NCT07362992
- Testing
- Tranexamic Acid (Topical)
- Where
- 4 sites in Israel
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Wolfson Medical Center
Obstetric Labour, Premature
Study to Investigate the Pharmacokinetics (PK), Safety and Tolerability of Retosiban in Healthy Japanese Women
This study in healthy, adult Japanese women will characterize the PK, safety and tolerability of retosiban at the therapeutic doses planned to be evaluated in Phase 3.
- Trial name
- NCT02377414
- Testing
- Retosiban solution for Infusion
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Depression, Postpartum, Pregnancy
Labor Pain and Postpartum Behavioral Health Outcomes Study
In this pilot prospective longitudinal observational study, women who are pregnant and who will be experiencing childbirth for the first time will be recruited at the third trimester and observed longitudinally for psychiatric…
- Conditions
- Depression, Postpartum, Pregnancy, Child Development, Pain
- Trial name
- LPPD (NCT02692404)
- Where
- 2 sites in United States
- Volunteers
- 199 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Hypertension, Premature Birth
Trial of Exercise to Prevent HypeRtension in Young Adults
TEPHRA investigates the effect of exercise on blood pressure and other cardiovascular factors in young adults with different birth histories.
- Trial name
- TEPHRA (NCT02723552)
- Testing
- Aerobic Exercise
- Where
- United Kingdom
- Volunteers
- 203 people, healthy volunteers welcome
- Sponsor
- University of Oxford
Preterm Birth
Preventing Preterm Birth With a Pessary
The primary objective of this study, is to determine the effect of a Cup pessary, a device that is currently readily available in the USA and similar in design to the Arabin pessary, on the incidence of delivery prior to 37 weeks…
- Trial name
- PrePPy (NCT01380158)
- Testing
- Cup pessary (Bioteque America, Inc)
- Where
- 3 sites in United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Medstar Health Research Institute
Sleep
Sleep-wakefulness Status in Preterm Infants
This study was conducted to compare the effectiveness of three stair positioning pillows and positioning materials on the sleep-wakefulness status of preterm infants.
- Trial name
- NCT06664749
- Testing
- Three stair position pillow group, Positioning material group
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Harran University
Breast Milk, Digestion
The Effect of Breast Milk Smell on Nutrition in Preterms
The study was planned to determine the effect of breast milk odor applied during gavage feeding on early feeding cues of preterm newborns, the transition time to oral feeding and abdominal perfusion.
- Conditions
- Breast Milk, Digestion, Nutrition, Smell Stimulation
- Trial name
- NCT04843293
- Testing
- Olfactory stimulation
- Where
- Turkey (Türkiye)
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Selcuk University
Preterm Labor
Preterm Labor Prediction by Cervical Contour in Ultrasound
Cervical length is a already known predictor for preterm labor. In this study the investigators want to examining the hypothesis that cervical curvature is also a predictor for preterm labor and that moderate transducer pressure…
- Trial name
- NCT01912508
- Where
- Israel
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Meir Medical Center
Post Partum Haemorrhage
Compare Efficacy of Oxytocin Administrations on Postpartum Uterine Contractility
This is a Phase I open-label, parallel-group clinical study in healthy term pregnant females undergoing a caesarean section. Two administrations of oxytocin will be tested, after which uterine contractility will be assessed.
- Trial name
- NCT02908126
- Testing
- Oxytocin
- Where
- Sweden
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- Oxytone Bioscience BV
Management of Delivery
Effectiveness of Placental Drainage in the Third Stage of Labor: a Randomized Clinical Trial
The purpose of this study is to determine if placental drainage shortens third period of labor and reduces postpartum blood lost.
- Trial name
- PLADRAINAGE (NCT01655576)
- Testing
- Placental drainage
- Where
- Brazil
- Volunteers
- 226 people, healthy volunteers welcome
- Sponsor
- Instituto Materno Infantil Prof. Fernando Figueira
Preterm Premature Rupture of Fetal Membranes, Induction of Labor Affected Fetus / Newborn
A Randomized Trial of Induction Methods in Premature Rupture of Membranes
This study evaluates the addition of transcervical Foley catheter balloon and vaginal prostaglandin E2 induction in premature rupture of membranes.
- Trial name
- NCT03744078
- Testing
- Foley balloon catheter
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Zeynep Kamil Maternity and Pediatric Research and Training Hospital
Postpartum Hemorrhage, Twin
Oxytocin at Elective Cesarean Deliveries: A Dose-finding Study in Women With Twin Pregnancy
Postpartum hemorrhage (PPH) due to uterine atony is a major cause of maternal morbidity and mortality. Uterotonic drugs are used to improve the muscle tone of the uterus after birth and these are effective at reducing the…
- Trial name
- NCT04025658
- Testing
- Oxytocin
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Language Development
Language Development in Preterm Children
This research investigates the ways in which preterm birth affects how very young children learn to speak and understand language, and how older children gain efficiency in language processing.
- Trial name
- NCT01599780
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Stanford University
Vitamin d Deficiency, Preeclampsia
25- Hydroxyvitamin D Levels in Pregnancy and Effects on Pregnancy Related Disorders
Evaluation of 25- Hydroxyvitamin D levels in pregnant women in Austria and potential related disorders Hypothesis: Austrian pregnant women are Vitamin D deficient Present vitamin D supplementation in pregnancy is insufficient…
- Conditions
- Vitamin d Deficiency, Preeclampsia, Preterm Delivery, Gestational Hypertension
- Trial name
- VIDIS (NCT04637880)
- Where
- Austria
- Volunteers
- 249 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Labor Complication
Traditional WHO Partograph and Korle-Bu Modified WHO Partograph for Uncomplicated Labour
Brief Background: The partograph is a graphical representation of the events in the first stage of labour. It is an instrument used in monitoring the well being of both the pregnant woman and her fetus (es) as they go through the…
- Trial name
- NCT05837559
- Testing
- Korle-Bu Modified WHO Partograph for Uncomplicated Labour
- Where
- Ghana
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- University of Ghana Medical School
Feeding Intolerance, Necrotizing Enterocolitis
Evaluation of Feeding Intolerance in Premature Infants Using Near Infrared Spectroscopy
Nowadays feeding intolerance (FI) is a common condition among preterm infants. It has been estimated that 16%-29% of premature infants admitted to neonatal intensive care units (NICUs) develop feeding intolerance at some point…
- Conditions
- Feeding Intolerance, Necrotizing Enterocolitis, Premature Infant
- Trial name
- NIRS/NICU2 (NCT02534090)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Neonatal İntensive Care, Nutrition With A Chronobiological Approach
The Effect of PIOMI and Chronobiological Nutrition on Readiness for Feeding, Full Transition to Oral Feeding and Body Weight
This is a randomized controlled experimental study evaluating the effects of oral motor intervention and chronobiological approach to feeding model applied to preterm infants on feeding readiness, transition to total oral feeding…
- Conditions
- Neonatal İntensive Care, Nutrition With A Chronobiological Approach, Readiness For Feding, Body Weight
- Trial name
- PIOMI (NCT07306793)
- Testing
- PIOMI study group, Nutrition Study Group with a Chronobiological Approach, Control group
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Aydin Adnan Menderes University
Shoulder Dystocia, Simulation Based Medical Education
Simulation in Shoulder Dystocia Management
Shoulder dystocia is an unpredictable and unpredictable emergency obstetric condition that causes serious maternal and neonatal complications. Therefore, it requires immediate and effective intervention.
- Conditions
- Shoulder Dystocia, Simulation Based Medical Education, Midwifery
- Trial name
- NCT07009626
- Testing
- Computer-based high-validity birth simulator
- Where
- Turkey (Türkiye)
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- Sakarya University
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