Clinical trials: Labor Pain, open to volunteers
Labor Pain
Analgesic Efficacy and Obstetric Effects of Tramadol, Paracetamol and Placebo in Active Labor
This randomized, double-blind, placebo-controlled trial aims to compare the analgesic efficacy and obstetric effects of tramadol (100 mg IV) versus paracetamol (1 g IV) versus placebo (saline solution) in nulliparous women during…
- Trial name
- TRAMPA (NCT07440069)
- Testing
- Tramadol Hydrochloride, Paracetamol (acetaminophen)
- Where
- 2 sites in Honduras
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Universidad Nacional Autonoma de Honduras
Labor Induction
Pain Control for Cervical Ripening Balloon
No standard of care exists for pain management during cervical ripening balloon placement. The purpose of this study is to evaluate if vaginal topical lidocaine reduces pain related to cervical ripening balloon placement during…
- Trial name
- NCT07268118
- Testing
- topical vaginal application lidocaine gel
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- Beth Israel Deaconess Medical Center
Labor Pain
Changes in Velocimetric Indices of Uterine and Umbilical Arteries Before and After Combined Spinal-epidural Analgesia in Laboring Women (PART II)
Combined spinal-epidural (CSE) for labor analgesia has been used for many years and is practiced commonly at our institution, especially when the patient requests immediate pain relief.
- Trial name
- NCT06655675
- Testing
- Ultrasound
- Where
- Canada
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Pregnancy, Labor Pain
Storytelling for Provider Empathy & Patient Trust in Obstetric Care
Aim 3 is a provider-focused pilot randomized controlled trial evaluating a digital storytelling intervention to increase obstetric care providers' empathy and to examine associations with postpartum patient trust.
- Trial name
- NCT07588308
- Testing
- Digital storytelling video + written reflection, General culturally sensitive care materials
- Volunteers
- 120 people
- Sponsor
- Duke University
Back Pain, Neck Pain
Workplace Exercise Therapy With or Without Manual Therapy in Chronic Spinal Pain
Implementing workplace strategies to manage symptoms in office workers with chronic nonspecific spinal pain (CNSP) may improve both health- and work-related outcomes, as adherence to these interventions is more feasible in this…
- Conditions
- Back Pain, Neck Pain, Low Back Pain
- Trial name
- NCT07251959
- Testing
- Exercise therapy, Manual Therapy
- Where
- Spain
- Volunteers
- 60 people
- Sponsor
- Catholic University of Murcia
Labor Pain, Labor Anxiety
Effectiveness of Sacral Massage on Labor Pain, Depression, Stress, and Anxiety
to identify the effectiveness of sacral massage on labor pain, depression, stress, and anxiety: A randomized clinical trial
- Conditions
- Labor Pain, Labor Anxiety, Labor Stress, Labor Depression
- Trial name
- ESMLPDAS (NCT07501598)
- Testing
- Sacral Massage
- Volunteers
- 193 people, healthy volunteers welcome
- Sponsor
- University of Basrah
Labor Pain
Continuous Remote Vital Sign Monitoring During Labour Analgesia With Remifentanil
Continuous remote vital sign monitoring during labour analgesia with remifentanil - a prospective observational study Remifentanil PCA represents a well-tolerated, effective and valuable option for labour analgesia, yet its wider…
- Trial name
- NCT07167498
- Testing
- Intermittent midwife absence during remote monitoring of remifentanil PCA in labour
- Where
- Denmark
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Nordsjaellands Hospital
MSK Conditions
Feasibility and Acceptability of an Evidence-Informed Virtual Intervention to Reduce Perceptions of Injustice Following Work Injury
Many individuals who have sustained disabling injuries in the workplace react to their situation with a sense of 'injustice'. Research over the past 20 years has revealed that, interpreting one's post-injury life situation as…
- Trial name
- NCT07072702
- Testing
- Managing Post-Injury Challenges (MPIC)
- Where
- Canada
- Volunteers
- 75 people
- Sponsor
- McGill University
Rotator Cuff-related Shoulder Pain, Shoulder Osteoarthritis
Could a Feedback Device Help Manage Work-related Shoulder Disorders?
Work-related shoulder pain is a common problem with significant socio-economic repercussions. The impact of these disorders on workers is considerable, particularly in terms of pain, disability and reduced quality of life.
- Conditions
- Rotator Cuff-related Shoulder Pain, Shoulder Osteoarthritis, Rheumatoid Arthritis (RA)
- Trial name
- NCT06693479
- Testing
- Shoulder watch load (SWL) feedback, Education
- Where
- Canada
- Volunteers
- 42 people
- Sponsor
- Laval University
Gynecological; Surgery (Previous), Causing Obstructed Labor
Impact of Early Physiotherapy on Pain, Quality of Life, Pelvic Floor Function, and Sexual Health Post-Episiotomy
Surgical incision of the perineum and the posterior vaginal wall during a vaginal delivery (episiotomy) is among the most common surgical procedures performed in obstetrics.
- Trial name
- NCT06568406
- Testing
- Physiotherapy, Urogynaecology
- Where
- Czechia
- Volunteers
- 250 people
- Sponsor
- Brno University Hospital
Anxiety
Pre-Examination Reflexology for Anxiety and Pain During Pelvic Examination
The purpose of this study is to evaluate whether a brief standardized reflexology session administered before the first pelvic examination reduces maternal state anxiety among term pregnant women admitted for induction of labor.
- Trial name
- NCT07910136
- Testing
- Pre-Examination Reflexology
- Where
- Israel
- Volunteers
- 120 people
- Sponsor
- Goni Sintov
Labor, Induced
Topical Anesthesia During Catheter Insertion for Cervical Ripening (TOLERANCE)
The goal of this RCT is to learn if application of topical anesthetic cream to the perineum and posterior wall of vagina prior to balloon catheter insertion as part of labor induction will reduce pain levels experienced by…
- Trial name
- TOLERANCE (NCT07288021)
- Testing
- Topical Analgesia with Lidocaine-Prilocaine cream
- Where
- Israel
- Volunteers
- 200 people
- Sponsor
- Bnai Zion Medical Center
Pregnant Women, Labor Pain
Neuraxial Labor Analgesia and Offspring Neurodevelopment
How perinatal factors affect the long-term development of children has always been an issue of much concern. This study is designed to explore the potential impact of maternal neuraxial labor analgesia exposure on offspring…
- Conditions
- Pregnant Women, Labor Pain, Analgesia, Epidural, Infants
- Trial name
- NCT04964206
- Testing
- Neuraxial labor analgesia, No neuraxial labor analgesia
- Where
- 2 sites in China
- Volunteers
- 4,645 people
- Sponsor
- Dong-Xin Wang
18 Years and Older, Term Pregnancy
The Effect of the World Health Organisation-Based Intrapartum Care Model on Labour Pain, Comfort, Satisfaction and Postpartum Depression
This randomized controlled trial aims to evaluate the effects of the World Health Organization-based intrapartum care model on labour pain, labour comfort, childbirth satisfaction, and postpartum depression.
- Trial name
- WHO-ICARE Tria (NCT07451691)
- Testing
- WHO-ICARE Trial
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Kahramanmaras Sutcu Imam University
Retinopathy of Prematurity (ROP)
The Effect of Two Non-Pharmacological Methods on Pain During Retinopathy Examination
The goal of this randomized controlled trial is to determine the effect of reverse kangaroo care position and ROP (Retinopathy of Prematurity) position applied during ROP examination in premature infants on pain.
- Trial name
- NCT06694103
- Testing
- Reverse Kangaroo Care Position, ROP Position
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Sinem Basdemir
Injection Fear, Injection Pain Prevention
Does Ethyl Chloride Spray Work?
A procedure frequently performed by orthopaedic providers is the administration of corticosteroid injections for the management of various soft tissues and joint-related conditions, such as osteoarthritis, tendinitis, carpal…
- Conditions
- Injection Fear, Injection Pain Prevention, Injection Complication
- Trial name
- NCT06651788
- Testing
- Ethyl Chloride, Cold Saline Spray
- Where
- United States
- Volunteers
- 246 people
- Sponsor
- University of Chicago
Obstetric Pain
Quality of Postoperative Analgesia and Functional Recovery After Elective Cesarean Delivery
Based on randomization, patients will receive a mixture for spinal anesthesia and will be followed in the following hours for the various outcomes and for functional recovery
- Trial name
- MoFe (NCT06355271)
- Testing
- Fentanyl 1, Fentanyl2, Fentanyl 3
- Where
- Switzerland
- Volunteers
- 63 people
- Sponsor
- Ente Ospedaliero Cantonale, Bellinzona
Chronic Non-Cancer Pain, Opioid Use Disorder
Long-Term Opioid Therapy in Chronic Non-Cancer Pain: Risks and Benefits
The study investigates long-term opioid treatment in patients with chronic non-cancer pain (CNCP). The study aims to prospectively identify predictive factors for work ability and for developing opioid use disorder (according to…
- Trial name
- NCT06063902
- Where
- Sweden
- Volunteers
- 1,000 people
- Sponsor
- Uppsala University
Labor Pain, Satisfaction
Effects of Pilates Ball and Sacral Massage Applications on Labor Pain, Labor Duration and Childbirth Satisfaction
As researchers, we believe that Pilates ball and manual sacral massage applications can be easily and cost-free applied in maternity clinics in our country.
- Trial name
- NCT06927531
- Testing
- sacral massage, pilates ball
- Where
- Turkey (Türkiye)
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Ege University
Pain Management, C Section
Pain After Scheduled Cesarean Delivery: Spinal Morphine With or Without Levobupivacaine Wound Infiltration
The goal of this observational study is to learn whether injecting a numbing medicine (levobupivacaine, a local anesthetic) into the surgical wound at the end of a cesarean delivery improves pain control in women who also receive…
- Conditions
- Pain Management, C Section, Obstetric Pain, Levobupivacaine
- Trial name
- LEVO-CS (NCT07859956)
- Testing
- Levobupivacaine, Intrathecal Morphine
- Where
- Colombia
- Volunteers
- 336 people
- Sponsor
- Fundación Santa Fe de Bogota